α-Synuclein in Lewy bodies
Spillantini, Maria Grazia, Schmidt, Marie Luise, Lee, Virginia M.-Y., Trojanowski, John Q., Jakes, Ross, Goedert, Michel·1997·Nature
DOI 10.1038/42166
Cited by (225)
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- Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodiesErskine, Daniel, Ding, Jinhui, Thomas, Alan J., Kaganovich, Alice, Khundakar, Ahmad A., Hanson, Peter S., Taylor, John‐Paul, McKeith, Ian G., Attems, Johannes, Cookson, Mark R. et al. · 2018 · Movement Disorders
- Dose- and time-dependent α-synuclein aggregation induced by ferric iron in SK-N-SH cellsLi, Wen-Jing, Jiang, Hong, Song, Ning, Xie, Jun-Xia · 2010 · Neuroscience Bulletin
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- Neuroprotective Effects of Trehalose and Sodium Butyrate on Preformed Fibrillar Form of α-Synuclein-Induced Rat Model of Parkinson’s DiseaseKakoty, Violina, K C, Sarathlal, Dubey, Sunil Kumar, Yang, Chih-Hao, Taliyan, Rajeev · 2021 · ACS Chemical Neuroscience
- Differential seeding and propagating efficiency of α-synuclein strains generated in different conditionsLiu, Di, Guo, Jian-Jun, Su, Ji-Hui, Svanbergsson, Alexander, Yuan, Lin, Haikal, Caroline, Li, Wen, Gouras, Gunnar, Li, Jia-Yi · 2021 · Translational Neurodegeneration
- Peripheral administration of the Class-IIa HDAC inhibitor MC1568 partially protects against nigrostriatal neurodegeneration in the striatal 6-OHDA rat model of Parkinson’s diseaseMazzocchi, Martina, Goulding, Susan R., Morales-Prieto, Noelia, Foley, Tara, Collins, Louise M., Sullivan, Aideen M., O'Keeffe, Gerard W. · 2022 · Brain, Behavior, and Immunity
- Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin-proteasome system in PC12D cellsKawahata, Ichiro, Tokuoka, Hirofumi, Parvez, Hasan, Ichinose, Hiroshi · 2009 · Journal of Neural Transmission
- Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseasesSokratian, Arpine, Zhou, Ye, Tatli, Meltem, Burbidge, Kevin J., Xu, Enquan, Viverette, Elizabeth, Donzelli, Sonia, Duda, Addison M., Yuan, Yuan, Li, Huizhong et al. · 2024 · Science Advances
- A short dasatinib and quercetin treatment is sufficient to reinstate potent adult neuroregenesis in the aged killifishVan houcke, Jolien, Mariën, Valerie, Zandecki, Caroline, Ayana, Rajagopal, Pepermans, Elise, Boonen, Kurt, Seuntjens, Eve, Baggerman, Geert, Arckens, Lutgarde · 2023 · npj Regenerative Medicine
- Sleep disturbances in Parkinson's disease patients and management optionsClaassen, Daniel · 2011 · Nature and Science of Sleep
- Dysfunction of serotonergic neurons in Parkinson’s disease and dyskinesiaVegas-Suarez, Sergio, Paredes-Rodriguez, Elena, Aristieta, Asier, Lafuente, Jose V., Miguelez, Cristina, Ugedo, Luisa · 2019 · International Review of Neurobiology
- The N Terminus of α‐Synuclein Forms Cu
<sup>II</sup>
‐Bridged OligomersDrew, Simon C. · 2015 · Chemistry – A European Journal
- Exploring the connection between the gut microbiome and parkinson's disease symptom progression and pathology: implications for supplementary treatment optionsChan, Dennis G., Ventura, Katelyn, Villeneuve, Ally, Du Bois, Paul, Holahan, Matthew R. · 2022 · Journal of Parkinson's Disease
- Molecular Communication Between Neuronal Networks and Intestinal Epithelial Cells in Gut Inflammation and Parkinson’s DiseaseDrobny, Alice, Ngo, Phuong A., Neurath, Markus F., Zunke, Friederike, López-Posadas, Rocío · 2021 · Frontiers in Medicine
- In vivo imaging of synaptic density with [11C]UCB-J PET in two mouse models of neurodegenerative diseaseXiong, Mengfei, Roshanbin, Sahar, Rokka, Johanna, Schlein, Eva, Ingelsson, Martin, Sehlin, Dag, Eriksson, Jonas, Syvänen, Stina · 2021 · NeuroImage
- A comprehensive genetic study of the proteasomal subunit S6 ATPase in German Parkinson’s disease patients.Wahl, Claudia, Kautzmann, Sabine, Krebiehl, Guido, Strauss, Karsten, Woitalla, Dirk, Müller, Thomas, Bauer, Peter, Riess, Olaf, Krüger, Rejko · 2008 · Journal of Neural Transmission
- Comparison of the 3D structures of mouse and human α-synuclein fibrils by solid-state NMR and STEMHwang, Songhwan, Fricke, Pascal, Zinke, Maximilian, Giller, Karin, Wall, Joseph S., Riedel, Dietmar, Becker, Stefan, Lange, Adam · 2019 · Journal of Structural Biology
- AlphaFold Prediction of Structural Ensembles of Disordered ProteinsBrotzakis, Z. Faidon, Zhang, Shengyu, Vendruscolo, Michele · 2023
- A review of proposed mechanisms for neurodegenerative diseaseKelser, Benjamin M., Teichner, Eric M., Subtirelu, Robert C., Hoss, Kevin N. · 2024 · Frontiers in Aging Neuroscience
- Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosomeIqbal, Anila, Baldrighi, Marta, Murdoch, Jennifer N., Fleming, Angeleen, Wilkinson, Christopher J. · 2020 · Biology Open
- Engineered Extracellular Vesicles/Exosomes as a New Tool against Neurodegenerative DiseasesFerrantelli, Flavia, Chiozzini, Chiara, Leone, Patrizia, Manfredi, Francesco, Federico, Maurizio · 2020 · Pharmaceutics
- Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synucleinHowe, Jacob W., Sortwell, Caryl E., Duffy, Megan F., Kemp, Christopher J., Russell, Christopher P., Kubik, Michael, Patel, Pooja, Luk, Kelvin C., El-Agnaf, Omar M.A., Patterson, Joseph R. · 2021 · Parkinsonism & Related Disorders
- Disruption of α-Synuclein Proteostasis in the Striatum and Midbrain of Long-term Ovariectomized Female MiceZhou, Linfeng, Li, Yun, Wang, Min, Han, Wenjing, Chen, Qiang, Zhang, Ji, Sun, Bo, Fan, Yi · 2023 · Neuroscience
- Fluid markers of synapse degeneration in synucleinopathiesCervantes González, Alba, Belbin, Olivia · 2022 · Journal of Neural Transmission