α-Synuclein in Lewy bodies

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Items 101–200 of 225

1. Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases
   Tsigelny, Igor F., Crews, Leslie, Desplats, Paula, Shaked, Gideon M., Sharikov, Yuriy, Mizuno, Hideya, Spencer, Brian, Rockenstein, Edward, Trejo, Margarita, Platoshyn, Oleksandr et al. · 2008 · PLoS ONE · Retracted
2. Reversible Inhibition of α-Synuclein Fibrillization by Dopaminochrome-mediated Conformational Alterations
   Norris, Erin H., Giasson, Benoit I., Hodara, Roberto, Xu, Shaohua, Trojanowski, John Q., Ischiropoulos, Harry, Lee, Virginia M.-Y. · 2005 · Journal of Biological Chemistry
3. Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype
   Minakaki, Georgia, Menges, Stefanie, Kittel, Agnes, Emmanouilidou, Evangelia, Schaeffner, Iris, Barkovits, Katalin, Bergmann, Anna, Rockenstein, Edward, Adame, Anthony, Marxreiter, Franz et al. · 2018 · Autophagy
4. Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo
   Angot, Elodie, Steiner, Jennifer A., Lema Tomé, Carla M., Ekström, Peter, Mattsson, Bengt, Björklund, Anders, Brundin, Patrik · 2012 · PLoS ONE
5. Cellular senescence and Alzheimer disease: the egg and the chicken scenario
   Saez-Atienzar, Sara, Masliah, Eliezer · 2020 · Nature Reviews Neuroscience
6. T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?
   Appel, Stanley H., Beers, David R., Henkel, Jenny S. · 2010 · Trends in Immunology
7. Neurological and Neurodegenerative Alterations in a Transgenic Mouse Model Expressing Human α-Synuclein under Oligodendrocyte Promoter: Implications for Multiple System Atrophy
   Shults, Clifford W., Rockenstein, Edward, Crews, Leslie, Adame, Anthony, Mante, Michael, Larrea, Gabriel, Hashimoto, Makoto, Song, David, Iwatsubo, Takeshi, Tsuboi, Kyoko et al. · 2005 · The Journal of Neuroscience
8. Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies
   Uchihara, Toshiki, Giasson, Benoit I. · 2016 · Acta Neuropathologica
9. Role of α-Synuclein in Inducing Innate and Adaptive Immunity in Parkinson Disease
   Allen Reish, Heather E., Standaert, David G. · 2015 · Journal of Parkinson’s Disease
10. STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy
    Hinkle, Jared T., Patel, Jaimin, Panicker, Nikhil, Karuppagounder, Senthilkumar S., Biswas, Devanik, Belingon, Bonn, Chen, Rong, Brahmachari, Saurav, Pletnikova, Olga, Troncoso, Juan C. et al. · 2022 · Proceedings of the National Academy of Sciences
11. Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage
    Lindström, Veronica, Gustafsson, Gabriel, Sanders, Laurie H., Howlett, Evan H., Sigvardson, Jessica, Kasrayan, Alex, Ingelsson, Martin, Bergström, Joakim, Erlandsson, Anna · 2017 · Molecular and Cellular Neuroscience
12. NACP/α-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy
    Arima, K., Uéda, Kenji, Sunohara, Nobuhiko, Arakawa, Kenji, Hirai, Shigeo, Nakamura, Minako, Tonozuka-Uehara, Haruko, Kawai, Mitsuru · 1998 · Acta Neuropathologica
13. Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression
    Henry, Anastasia G., Aghamohammadzadeh, Soheil, Samaroo, Harry, Chen, Yi, Mou, Kewa, Needle, Elie, Hirst, Warren D. · 2015 · Human Molecular Genetics
14. Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain
    Rostami, Jinar, Fotaki, Grammatiki, Sirois, Julien, Mzezewa, Ropafadzo, Bergström, Joakim, Essand, Magnus, Healy, Luke, Erlandsson, Anna · 2020 · Journal of Neuroinflammation
15. Inflammation is genetically implicated in Parkinson’s disease
    Dzamko, N., Geczy, C.L, Halliday, G.M · 2015 · Neuroscience
16. Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
    Grassi, Diego, Howard, Shannon, Zhou, Minghai, Diaz-Perez, Natalia, Urban, Nicolai T., Guerrero-Given, Debbie, Kamasawa, Naomi, Volpicelli-Daley, Laura A., LoGrasso, Philip, Lasmézas, Corinne Ida · 2018 · Proceedings of the National Academy of Sciences
17. In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells
    Dettmer, Ulf, Newman, Andrew J., Luth, Eric S., Bartels, Tim, Selkoe, Dennis · 2013 · Journal of Biological Chemistry
18. Interaction between Aβ Peptide and α Synuclein: Molecular Mechanisms in Overlapping Pathology of Alzheimer’s and Parkinson’s in Dementia with Lewy Body Disease
    Mandal, Pravat K., Pettegrew, Jay W., Masliah, Eliezer, Hamilton, Ronald L., Mandal, Ratna · 2006 · Neurochemical Research
19. Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology
    Manfredsson, Fredric P., Luk, Kelvin C., Benskey, Matthew J., Gezer, Aysegul, Garcia, Joanna, Kuhn, Nathan C., Sandoval, Ivette M., Patterson, Joseph R., O'Mara, Alana, Yonkers, Reid et al. · 2018 · Neurobiology of Disease
20. rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration
    Oliveras-Salvá, Marusela, Van der Perren, Anke, Casadei, Nicolas, Stroobants, Stijn, Nuber, Silke, D’Hooge, Rudi, Van den Haute, Chris, Baekelandt, Veerle · 2013 · Molecular Neurodegeneration
21. Circadian dysfunction in a mouse model of Parkinson's disease
    Kudo, Takashi, Loh, Dawn H., Truong, Danny, Wu, Yingfei, Colwell, Christopher S. · 2011 · Experimental Neurology
22. Exogenous α-synuclein induces toll-like receptor 4 dependent inflammatory responses in astrocytes
    Rannikko, Emmy H., Weber, Stephanie S., Kahle, Philipp J. · 2015 · BMC Neuroscience
23. Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease: A Phase 2 Randomized Clinical Trial
    Pagan, Fernando. L., Hebron, Michaeline L., Wilmarth, Barbara, Torres-Yaghi, Yasar, Lawler, Abigail, Mundel, Elizabeth E., Yusuf, Nadia, Starr, Nathan J., Anjum, Muhammad, Arellano, Joy et al. · 2020 · JAMA Neurology
24. Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives
    Huang, Bei, Chau, Steven W. H., Liu, Yaping, Chan, Joey W. Y., Wang, Jing, Ma, Suk Ling, Zhang, Jihui, Chan, Paul K. S., Yeoh, Yun Kit, Chen, Zigui et al. · 2023 · Nature Communications
25. Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
    Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D. · 2014 · Scientific Reports
26. Inflammation in Parkinson’s disease: role of glucocorticoids
    Herrero, María-Trinidad, Estrada, Cristina, Maatouk, Layal, Vyas, Sheela · 2015 · Frontiers in Neuroanatomy
27. Lewy Body Pathology in Alzheimer's Disease
    Kotzbauer, Paul T., Tojanowski, John Q., Lee, Virginia M. V. · 2001 · Journal of Molecular Neuroscience
28. α-Synuclein-positive structures in cases with sporadic Alzheimer’s disease: morphology and its relationship to tau aggregation
    Arai, Yasushi, Yamazaki, Mineo, Mori, Osamu, Muramatsu, Hiromi, Asano, Goro, Katayama, Yasuo · 2001 · Brain Research
29. α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration
    Abdelmotilib, Hisham, Maltbie, Tyler, Delic, Vedad, Liu, Zhiyong, Hu, Xianzhen, Fraser, Kyle B., Moehle, Mark S., Stoyka, Lindsay, Anabtawi, Nadia, Krendelchtchikova, Valentina et al. · 2017 · Neurobiology of Disease
30. α-Synuclein Reactive Antibodies as Diagnostic Biomarkers in Blood Sera of Parkinson's Disease Patients
    Yanamandra, Kiran, Gruden, Marina A., Casaite, Vida, Meskys, Rolandas, Forsgren, Lars, Morozova-Roche, Ludmilla A. · 2011 · PLoS ONE
31. Immune Dysregulation in Autism Spectrum Disorder: What Do We Know about It?
    Robinson-Agramonte, Maria de los Angeles, Noris García, Elena, Fraga Guerra, Jarasca, Vega Hurtado, Yamilé, Antonucci, Nicola, Semprún-Hernández, Neomar, Schultz, Stephen, Siniscalco, Dario · 2022 · International Journal of Molecular Sciences
32. Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease
    Dijkstra, Anke A., Ingrassia, Angela, de Menezes, Renee X., van Kesteren, Ronald E., Rozemuller, Annemieke J. M., Heutink, Peter, van de Berg, Wilma D. J. · 2015 · PLOS ONE
33. Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation
    Liu, Guoxiang, Yu, Jia, Ding, Jinhui, Xie, Chengsong, Sun, Lixin, Rudenko, Iakov, Zheng, Wang, Sastry, Namratha, Luo, Jing, Rudow, Gay et al. · 2014 · Journal of Clinical Investigation
34. A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila
    Zhang, Sheng, Binari, Richard, Zhou, Rui, Perrimon, Norbert · 2010 · Genetics
35. Toll-like receptor expression in the blood and brain of patients and a mouse model of Parkinson's disease
    Drouin-Ouellet, J., St-Amour, I., Saint-Pierre, M., Lamontagne-Proulx, J., Kriz, J., Barker, R. A., Cicchetti, F. · 2015 · International Journal of Neuropsychopharmacology
36. The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases
    Rodríguez-Rodríguez, Cristina, Telpoukhovskaia, Maria, Orvig, Chris · 2012 · Coordination Chemistry Reviews
37. Oxidative and nitrative alpha‐synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies
    Schildknecht, Stefan, Gerding, Hanne R., Karreman, Christiaan, Drescher, Malte, Lashuel, Hilal A., Outeiro, Tiago F., Di Monte, Donato A., Leist, Marcel · 2013 · Journal of Neurochemistry
38. Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease
    Tóth, Gergely, Gardai, Shyra J., Zago, Wagner, Bertoncini, Carlos W., Cremades, Nunilo, Roy, Susan L., Tambe, Mitali A., Rochet, Jean-Christophe, Galvagnion, Celine, Skibinski, Gaia et al. · 2014 · PLoS ONE
39. Extracellular α-synuclein levels are regulated by neuronal activity
    Yamada, Kaoru, Iwatsubo, Takeshi · 2018 · Molecular Neurodegeneration
40. Toll-like receptors and their therapeutic potential in Parkinson’s disease and α-synucleinopathies
    Kouli, Antonina, Horne, C.B., Williams-Gray, C.H. · 2019 · Brain Behavior and Immunity
41. A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptides
    Gallardo, Gilbert, Schlüter, Oliver M, Südhof, Thomas C · 2008 · Nature Neuroscience
42. Mutant α-Synuclein Overexpression Mediates Early Proinflammatory Activity
    Su, Xiaomin, Federoff, Howard J., Maguire-Zeiss, Kathleen A. · 2009 · Neurotoxicity Research
43. <i>In Vivo</i>Positron Emission Tomographic Imaging of Glial Responses to Amyloid-β and Tau Pathologies in Mouse Models of Alzheimer's Disease and Related Disorders
    Maeda, Jun, Zhang, Ming-Rong, Okauchi, Takashi, Ji, Bin, Ono, Maiko, Hattori, Satoko, Kumata, Katsushi, Iwata, Nobuhisa, Saido, Takaomi C., Trojanowski, John Q. et al. · 2011 · The Journal of Neuroscience
44. Healthspan Maintenance and Prevention of Parkinson's-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans
    Brunetti, Giovanni, Di Rosa, Gabriele, Scuto, Maria, Leri, Manuela, Stefani, Massimo, Schmitz-Linneweber, Christian, Calabrese, Vittorio, Saul, Nadine · 2020 · International Journal of Molecular Sciences
45. Low CSF Levels of Both α-Synuclein and the α-Synuclein Cleaving Enzyme Neurosin in Patients with Synucleinopathy
    Wennström, Malin, Surova, Yulia, Hall, Sara, Nilsson, Christer, Minthon, Lennart, Boström, Fredrik, Hansson, Oskar, Nielsen, Henrietta M. · 2013 · PLoS ONE
46. Intercellular Spread of Protein Aggregates in Neurodegenerative Disease
    Davis, Albert A., Leyns, Cheryl E.G., Holtzman, David M. · 2018 · Annual Review of Cell and Developmental Biology
47. Could a loss of α‐synuclein function put dopaminergic neurons at risk?
    Perez, Ruth G., Hastings, Teresa G. · 2004 · Journal of Neurochemistry
48. Tau filaments in neurodegenerative diseases
    Goedert, Michel · 2018 · FEBS Letters
49. Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice
    Sato, Shigeto, Uchihara, Toshiki, Fukuda, Takahiro, Noda, Sachiko, Kondo, Hiromi, Saiki, Shinji, Komatsu, Masaaki, Uchiyama, Yasuo, Tanaka, Keiji, Hattori, Nobutaka · 2018 · Scientific Reports
50. In vivo gastric detection of α-synuclein inclusions in Parkinson's disease
    Sánchez‐Ferro, Álvaro, Rábano, Alberto, Catalán, María José, Rodríguez‐Valcárcel, Fernando Canga, Díez, Servando Fernández, Herreros‐Rodríguez, Jaime, García‐Cobos, Elvira, Álvarez‐Santullano, Marina Mata, López‐Manzanares, Lydia, Mosqueira, Antonio J. et al. · 2015 · Movement Disorders
51. Microglial NLRP3 Inflammasome Activation Upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies
    Scheiblich, Hannah, Bousset, Luc, Schwartz, Stephanie, Griep, Angelika, Latz, Eicke, Melki, Ronald, Heneka, Michael T · 2021 · The Journal of Immunology
52. Repurposing Doxycycline for Synucleinopathies: Remodelling of α-Synuclein Oligomers towards Non-Toxic Parallel Beta-Sheet Structured Species
    González-Lizárraga, Florencia, Socías, Sergio B., Ávila, César L., Torres-Bugeau, Clarisa M., Barbosa, Leandro R. S., Binolfi, Andres, Sepúlveda-Díaz, Julia E., Del-Bel, Elaine, Fernandez, Claudio O., Papy-Garcia, Dulce et al. · 2017 · Scientific Reports
53. Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease
    Milanese, Chiara, Cerri, Silvia, Ulusoy, Ayse, Gornati, Simona V., Plat, Audrey, Gabriels, Sylvia, Blandini, Fabio, Di Monte, Donato A., Hoeijmakers, Jan H., Mastroberardino, Pier G. · 2018 · Cell Death &amp; Disease
54. Targeting dysregulated lipid metabolism for the treatment of Alzheimer's disease and Parkinson's disease: Current advancements and future prospects
    Tong, Bin, Ba, Yaoqi, Li, Zhengyang, Yang, Caidi, Su, Kangtai, Qi, Haodong, Zhang, Deju, Liu, Xiao, Wu, Yuting, Chen, Yixuan et al. · 2024 · Neurobiology of Disease
55. Pathogenic Mechanisms of Neurodegeneration in Parkinson Disease
    Mullin, Stephen, Schapira, Anthony H.V. · 2015 · Neurologic Clinics
56. Targeting receptor-ligand chemistry for drug delivery across blood-brain barrier in brain diseases
    Anthony, Danielle Paige, Hegde, Manasa, Shetty, Shreya S., Rafic, Thasneema, Mutalik, Srinivas, Rao, B.S. Satish · 2021 · Life Sciences
57. α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss
    Trudler, Dorit, Sanz-Blasco, Sara, Eisele, Yvonne S., Ghatak, Swagata, Bodhinathan, Karthik, Akhtar, Mohd Waseem, Lynch, William P., Piña-Crespo, Juan C., Talantova, Maria, Kelly, Jeffery W. et al. · 2021 · The Journal of Neuroscience
58. Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies
    Nelson, P. T., Kryscio, R. J., Jicha, G. A., Abner, E. L., Schmitt, F. A., Xu, L. O., Cooper, G., Smith, C. D., Markesbery, W. R. · 2009 · Neurology
59. Parkinsons Disease and other α-Synucleinopathies
    Goedert, Michel · 2001 · Clinical Chemistry and Laboratory Medicine
60. Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts
    Braidy, Nady, Gai, Wei-Ping, Xu, Ying Hua, Sachdev, Perminder, Guillemin, Gilles J, Jiang, Xing-Mai, Ballard, J William O, Horan, Martin P, Fang, Zhi Ming, Chong, Beng H et al. · 2013 · Translational Neurodegeneration
61. Striatal glutamatergic hyperactivity in Parkinson's disease
    Campanelli, F., Natale, G., Marino, G., Ghiglieri, V., Calabresi, P. · 2022 · Neurobiology of Disease
62. Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease
    Chu, Yaping, Bartus, Raymond T, Manfredsson, Fredric P, Olanow, C Warren, Kordower, Jeffrey H · 2020 · Brain
63. Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples
    Brenowitz, Willa D., Keene, C. Dirk, Hawes, Stephen E., Hubbard, Rebecca A., Longstreth, W.T., Woltjer, Randy L., Crane, Paul K., Larson, Eric B., Kukull, Walter A. · 2017 · Neurobiology of Aging
64. Endonuclease G mediates α‐synuclein cytotoxicity during Parkinson's disease
    Büttner, Sabrina, Habernig, Lukas, Broeskamp, Filomena, Ruli, Doris, Vögtle, F Nora, Vlachos, Manolis, Macchi, Francesca, Küttner, Victoria, Carmona‐Gutierrez, Didac, Eisenberg, Tobias et al. · 2013 · The EMBO Journal
65. Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration
    Zhang, Xiong, Xie, Wenjie, Qu, Shen, Pan, Tianhong, Wang, Xiaotong, Le, Weidong · 2005 · Biochemical and Biophysical Research Communications
66. Nigral overexpression of α-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome
    O’Donovan, Sarah M., Crowley, Erin K., Brown, Jillian R.‐M., O’Sullivan, Orla, O’Leary, Olivia F., Timmons, Suzanne, Nolan, Yvonne M., Clarke, David J., Hyland, Niall P., Joyce, Susan A. et al. · 2020 · Neurogastroenterology &amp; Motility
67. Parkinsonism: siblings share Helicobacter pylori seropositivity and facets of syndrome
    Charlett, A., Dobbs, R. J., Dobbs, S. M., Weller, C., Brady, P., Peterson, D.W. · 2009 · Acta Neurologica Scandinavica
68. C-terminal α-synuclein immunoreactivity in structures other than Lewy bodies in neurodegenerative disorders
    Takeda, A., Hashimoto, M., Mallory, M., Sundsumo, M., Hansen, L., Masliah, E. · 2000 · Acta Neuropathologica
69. The gut-brain axis and Parkinson disease: Clinical and pathogenetic relevance
    Menozzi, Elisa, Macnaughtan, Jane, Schapira, Anthony H. V. · 2021 · Annals of Medicine
70. Increased CSF α‐synuclein levels in Alzheimer's disease: Correlation with tau levels
    Slaets, Sylvie, Vanmechelen, Eugeen, Le Bastard, Nathalie, Decraemer, Hilde, Vandijck, Manu, Martin, Jean‐Jacques, De Deyn, Peter Paul, Engelborghs, Sebastiaan · 2014 · Alzheimer's &amp; Dementia
71. Calcium, Bioenergetics, and Parkinson’s Disease
    Zampese, Enrico, Surmeier, D. James · 2020 · Cells
72. Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration
    Peng, Wesley, Minakaki, Georgia, Nguyen, Maria, Krainc, Dimitri · 2019 · Neurotherapeutics
73. Long-term hyperglycemia aggravates α-synuclein aggregation and dopaminergic neuronal loss in a Parkinson’s disease mouse model
    Lv, Yi-Qing, Yuan, Lin, Sun, Yan, Dou, Hao-Wen, Su, Ji-Hui, Hou, Zhi-Pan, Li, Jia-Yi, Li, Wen · 2022 · Translational Neurodegeneration
74. Stimulatory effect of <b>α</b>‐synuclein on the tau‐phosphorylation by GSK‐3<b>β</b>
    Kawakami, Fumitaka, Suzuki, Minori, Shimada, Naoki, Kagiya, Go, Ohta, Etsuro, Tamura, Kei, Maruyama, Hiroko, Ichikawa, Takafumi · 2011 · The FEBS Journal
75. Quantitative neurohistological features of frontotemporal degeneration
    Arnold, Steven E., Han, Li-Ying, Clark, Christopher M., Grossman, Murray, Trojanowski, John Q. · 2000 · Neurobiology of Aging
76. O-GlcNAcase Inhibitor ASN90 is a Multimodal Drug Candidate for Tau and α-Synuclein Proteinopathies
    Permanne, Bruno, Sand, Astrid, Ousson, Solenne, Nény, Maud, Hantson, Jennifer, Schubert, Ryan, Wiessner, Christoph, Quattropani, Anna, Beher, Dirk · 2022 · ACS Chemical Neuroscience
77. Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease
    Pitcairn, Caleb, Wani, Willayat Yousuf, Mazzulli, Joseph R. · 2019 · Neurobiology of Disease
78. Cycles of Aberrant Synaptic Sprouting and Neurodegeneration in Alzheimer's and Dementia with Lewy Bodies
    Hashimoto, Makoto, Masliah, Eliezer · 2003 · Neurochemical Research
79. Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity
    Mohammad-Beigi, Hossein, Aliakbari, Farhang, Sahin, Cagla, Lomax, Charlotte, Tawfike, Ahmed, Schafer, Nicholas P., Amiri-Nowdijeh, Alireza, Eskandari, Hoda, Møller, Ian Max, Hosseini-Mazinani, Mehdi et al. · 2019 · Journal of Biological Chemistry
80. Gastrointestinal autonomic dysfunction in patients with Parkinson’s disease
    Kim, Joong-Seok, Sung, Hye-Young · 2015 · Journal of Movement Disorders
81. Microglia-mediated neuroinflammation and neurotrophic factor-induced protection in the MPTP mouse model of parkinson’s disease-lessons from transgenic mice
    Machado, Venissa, Zöller, Tanja, Attaai, Abdelraheim, Spittau, Björn · 2016 · International Journal of Molecular Sciences
82. α‐Synuclein promotes clathrin‐mediated NMDA receptor endocytosis and attenuates NMDA‐induced dopaminergic cell death
    Cheng, Furong, Li, Xin, Li, Yaohua, Wang, Chaodong, Wang, Tao, Liu, Guangwei, Baskys, Andrius, Uéda, Kenji, Chan, Piu, Yu, Shun · 2011 · Journal of Neurochemistry
83. Native Top-Down Mass Spectrometry and Ion Mobility MS for Characterizing the Cobalt and Manganese Metal Binding of α-Synuclein Protein
    Wongkongkathep, Piriya, Han, Jong Yoon, Choi, Tae Su, Yin, Sheng, Kim, Hugh I., Loo, Joseph A. · 2018 · Journal of the American Society for Mass Spectrometry
84. Early signs of colonic inflammation, intestinal dysfunction, and olfactory impairments in the rotenone-induced mouse model of Parkinson's disease
    Morais, Lívia H., Hara, Daniela B., Bicca, Maíra A., Poli, Anicleto, Takahashi, Reinaldo N. · 2018 · Behavioural Pharmacology
85. Ceftriaxone Blocks the Polymerization of α-Synuclein and Exerts Neuroprotective Effects in Vitro
    Ruzza, Paolo, Siligardi, Giuliano, Hussain, Rohanah, Marchiani, Anna, Islami, Mehmet, Bubacco, Luigi, Delogu, Giovanna, Fabbri, Davide, Dettori, Maria A., Sechi, Mario et al. · 2014 · ACS Chemical Neuroscience
86. Regulation of the neurodegenerative process associated to Parkinson's disease by CD4+ T-cells
    González, Hugo, Contreras, Francisco, Pacheco, Rodrigo · 2015 · Journal of Neuroimmune Pharmacology
87. Cholesterol homeostasis failure in the brain: Implications for synaptic dysfunction and cognitive decline
    Segatto, Marco, Leboffe, Loris, Trapani, Laura, Pallottini, Valentina · 2014 · Current Medicinal Chemistry
88. Neuroinflammation in Parkinson’s Disease Animal Models: A Cell Stress Response or a Step in Neurodegeneration?
    Cebrián, Carolina, Loike, John D., Sulzer, David · 2014 · Current Topics in Behavioral Neurosciences
89. Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease
    Eteleeb, Abdallah M., Novotny, Brenna C., Tarraga, Carolina Soriano, Sohn, Christopher, Dhungel, Eliza, Brase, Logan, Nallapu, Aasritha, Buss, Jared, Farias, Fabiana, Bergmann, Kristy et al. · 2024 · PLOS Biology
90. P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells
    Wilkaniec, Anna, Gąssowska, Magdalena, Czapski, Grzegorz A., Cieślik, Magdalena, Sulkowski, Grzegorz, Adamczyk, Agata · 2017 · Purinergic Signalling
91. The niche matters: Origin, function and fate of CNS-associated macrophages during health and disease
    Dalmau Gasull, Adrià, Glavan, Martina, Samawar, Sai K. Reddy, Kapupara, Kishan, Kelk, Joe, Rubio, Marina, Fumagalli, Stefano, Sorokin, Lydia, Vivien, Denis, Prinz, Marco · 2024 · Acta Neuropathologica
92. Rapid macropinocytic transfer of α-synuclein to lysosomes
    Bayati, Armin, Banks, Emily, Han, Chanshuai, Luo, Wen, Reintsch, Wolfgang E., Zorca, Cornelia E., Shlaifer, Irina, Del Cid Pellitero, Esther, Vanderperre, Benoit, McBride, Heidi M. et al. · 2022 · Cell Reports
93. The proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein—implications for Parkinson's disease.
    Marx, Frank P., Soehn, Anne S., Berg, Daniela, Melle, Christian, Schiesling, Carola, Lang, Mira, Kautzmann, Sabine, Strauss, Karsten M., Franck, Thomas, Engelender, Simone et al. · 2007 · The FASEB Journal
94. Upregulation of α‐synuclein by lipopolysaccharide and interleukin‐1 in human macrophages
    Tanji, Kunikazu, Mori, Fumiaki, Imaizumi, Tadaatsu, Yoshida, Hidemi, Matsumiya, Tomoh, Tamo, Wakako, Yoshimoto, Makoto, Odagiri, Hiroki, Sasaki, Mutsuo, Takahashi, Hitoshi et al. · 2002 · Pathology International
95. Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization
    Cheng, An, Shinoda, Yasuharu, Yamamoto, Tetsunori, Miyachi, Hiroyuki, Fukunaga, Kohji · 2019 · Brain Research
96. Peripheral insulin and amylin levels in Parkinson's disease
    Sánchez-Gómez, Almudena, Alcarraz-Vizán, Gema, Fernández, Manel, Fernández-Santiago, Rubén, Ezquerra, Mario, Cámara, Ana, Serrano, Mònica, Novials, Anna, Muñoz, Esteban, Valldeoriola, Francesc et al. · 2020 · Parkinsonism &amp; Related Disorders
97. Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway
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98. Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain
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