Clustering of perirhinal neurons with similar properties following visual experience in adult monkeys
Abstract
The functional organization of early visual areas seems to be largely determined during development. However, the organization of areas important for learning and memory, such as perirhinal cortex, may be modifiable in adults. To test this hypothesis, we recorded from pairs of neurons in perirhinal cortex of macaques while they viewed multiple complex stimuli. For novel stimuli, neuronal response preferences for pairs of nearby neurons and far-apart neurons were uncorrelated. However, after one day of experience with the stimuli, response preferences of nearby neurons became more similar. We conclude that specific visual experience induces development of clusters of perirhinal neurons with similar stimulus preferences.
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In the macaque perirhinal cortex, specific visual experience induces development of clusters of neurons with similar stimulus preferences.
“In the macaque perirhinal cortex, specific visual experience induces development of clusters of neurons with similar stimulus preferences (Erickson et al., 2000).”
From Specialization within the ventral stream: the case for the visual word form area (2004) · cites this paper as Erickson et al., 2000
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Specialization within the ventral stream: the case for the visual word form area
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- Authors
- Erickson, C. A., Jagadeesh, B., & Desimone, R.
- Affiliations
- University of Washington (US)
- Corresponding author
- Erickson, Cynthia A.
- Venue
- Nature Neuroscience
- Published
- 2000-11
- Volume
- 3
- Issue
- 11
- Pages
- 1143-1148
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W1495713168
- Cited by
- 115
- References
- 52
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 1 · 2020: 1 · 2019: 6 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 6 · 2014: 1 · 2013: 3 · 2012: 4
- FWCI
- 3.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- perirhinal cortex, neuronal clustering, visual experience, adult plasticity, macaque, stimulus preference, learning, single-unit recording
- MeSH terms
- Action Potentials, Animals, Discrimination Learning, Macaca mulatta, Male, Neurons, Pattern Recognition, Visual, Photic Stimulation, Visual Cortex
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