Mef2‐mediated transcription of the miR379–410 cluster regulates activity‐dependent dendritogenesis by fine‐tuning Pumilio2 protein levels
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A few miRNAs within the 14q32 cluster have been implicated in regulating synapse-specific genes and shown to exhibit neuronal-activity-dependent expression.
“Interestingly, a few miRNAs within this cluster have been implicated in regulating synapse-specific genes (Schratt et al., 2006) and shown to exhibit neuronal-activitydependent expression (Fiore et al., 2009).”
From Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes (2013) · cites this paper as Fiore et al., 2009
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Wayman, G. A., Impey, S., Marks, D., Saneyoshi, T., Grant, W. F., Derkach, V., & Soderling, T. R. (2006) · Neuron · doi:10.1016/j.neuron.2006.05.008 · Cited by 466 · cited 2× · see citing works
“To mimic activity-dependent dendritogenesis in vitro , cultured hippocampal neurons (DIV7) were treated for 6 h with KCl or BDNF and analysed by Sholl analysis (see Materials and methods) at DIV10 (Wayman et al , 2006).”
MethodCocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity
Pulipparacharuvil, S., Renthal, W., Hale, C. F., Taniguchi, M., Xiao, G., Kumar, A., Russo, S. J., Sikder, D., Dewey, C. M., Davis, M. M., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.020 · Cited by 281 · see citing works
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Research works printed but not linked: 46
- Bagni C, Greenough WT (2005) From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat Rev Neurosci 6: 376– 387 15861180
- Calabresi P, Picconi B, Tozzi A, Di Filippo M (2007) Dopamine-mediated regulation of corticostriatal synaptic plasticity. Trends Neurosci 30: 211– 219 17367873
- Chen G, Li W, Zhang QS, Regulski M, Sinha N, Barditch J, Tully T, Krainer AR, Zhang MQ, Dubnau J (2008) Identification of synaptic targets of Drosophila pumilio. PLoS Comput Biol 4: e1000026 18463699 PMC2265480
- Chen Y, Ghosh A (2005) Regulation of dendritic development by neuronal activity. J Neurobiol 64: 4– 10 15884010
- Cheng HY, Papp JW, Varlamova O, Dziema H, Russell B, Curfman JP, Nakazawa T, Shimizu K, Okamura H, Impey S, Obrietan K (2007) MicroRNA modulation of circadian-clock period and entrainment. Neuron 54: 813– 829 17553428 PMC2590749
- Fiore R, Siegel G, Schratt G (2008) MicroRNA function in neuronal development, plasticity and disease. Biochim Biophys Acta 1779: 471– 478 18194678
- Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME (2006) Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311: 1008– 1012 16484497
- Flavell SW, Greenberg ME (2008) Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system. Annu Rev Neurosci 31: 563– 590 18558867 PMC2728073
- Glazov EA, McWilliam S, Barris WC, Dalrymple BP (2008) Origin, evolution, and biological role of miRNA cluster in DLK-DIO3 genomic region in placental mammals. Mol Biol Evol 25: 939– 948 18281269
- Guo X, Lin Y, Horbinski C, Drahushuk KM, Kim IJ, Kaplan PL, Lein P, Wang T, Higgins D (2001) Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity. J Neurobiol 48: 120– 130 11438941
- He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, Powers S, Cordon-Cardo C, Lowe SW, Hannon GJ, Hammond SM (2005) A microRNA polycistron as a potential human oncogene. Nature 435: 828– 833 15944707 PMC4599349
- Hobert O (2007) miRNAs play a tune. Cell 131: 22– 24 17923083
- Hong EJ, West AE, Greenberg ME (2005) Transcriptional control of cognitive development. Curr Opin Neurobiol 15: 21– 28 15721740
- Kandel ER (2001) The molecular biology of memory storage: a dialogue between genes and synapses. Science 294: 1030– 1038 11691980
- Karres JS, Hilgers V, Carrera I, Treisman J, Cohen SM (2007) The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila. Cell 131: 136– 145 17923093
- Kiebler MA, Bassell GJ (2006) Neuronal RNA granules: movers and makers. Neuron 51: 685– 690 16982415
- Kosik KS (2006) The neuronal microRNA system. Nat Rev Neurosci 7: 911– 920 17115073
- Lonze BE, Ginty DD (2002) Function and regulation of CREB family transcription factors in the nervous system. Neuron 35: 605– 623 12194863
- Loots GG, Ovcharenko I (2004) rVISTA 2.0: evolutionary analysis of transcription factor binding sites. Nucleic Acids Res 32: W217– W221 15215384 PMC441521
- Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkun G, Sharp PA, Tabin CJ, McManus MT (2004) MicroRNA-responsive ‘sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet 36: 1079– 1083 15361871
- Marinescu VD, Kohane IS, Riva A (2005) The MAPPER database: a multi-genome catalog of putative transcription factor binding sites. Nucleic Acids Res 33: D91– D97 15608292 PMC540057
- Mee CJ, Pym EC, Moffat KG, Baines RA (2004) Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene. J Neurosci 24: 8695– 8703 15470135 PMC6729971
- Menon KP, Sanyal S, Habara Y, Sanchez R, Wharton RP, Ramaswami M, Zinn K (2004) The translational repressor Pumilio regulates presynaptic morphology and controls postsynaptic accumulation of translation factor eIF-4E. Neuron 44: 663– 676 15541314
- Redmond L, Kashani AH, Ghosh A (2002) Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription. Neuron 34: 999– 1010 12086646
- Richter JD (2007) CPEB: a life in translation. Trends Biochem Sci 32: 279– 285 17481902
- Sandelin A, Alkema W, Engstrom P, Wasserman WW, Lenhard B (2004) JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res 32: D91– D94 14681366 PMC308747
- Satoh D, Sato D, Tsuyama T, Saito M, Ohkura H, Rolls MM, Ishikawa F, Uemura T (2008) Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. Nat Cell Biol 10: 1164– 1171 18758452
- Schratt GM, Nigh EA, Chen WG, Hu L, Greenberg ME (2004) BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development. J Neurosci 24: 9366– 9377 PMC6729778 15317862
- Schratt GM, Tuebing F, Nigh EA, Kane CG, Sabatini ME, Kiebler M, Greenberg ME (2006) A brain-specific microRNA regulates dendritic spine development. Nature 439: 283– 289 16421561
- Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J (2004) A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res 14: 1741– 1748 15310658 PMC515320
- Shalizi A, Gaudilliere B, Yuan Z, Stegmuller J, Shirogane T, Ge Q, Tan Y, Schulman B, Harper JW, Bonni A (2006) A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. Science 311: 1012– 1017 16484498
- Shalizi AK, Bonni A (2005) Brawn for brains: the role of MEF2 proteins in the developing nervous system. Curr Top Dev Biol 69: 239– 266 16243602
- Shevtsova Z, Malik JM, Michel U, Bahr M, Kugler S (2005) Promoters and serotypes: targeting of adeno-associated virus vectors for gene transfer in the rat central nervous system in vitro and in vivo. Exp Physiol 90: 53– 59 15542619
- Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, Khudayberdiev S, Leuschner PF, Busch CJL, Kane C, Hübel K, Rengarajan B, Drepper C, Waldmann H, Kauppinen S, Greenberg ME, Draguhn A, Rehmsmeier M, Martinez J, Schratt G (2009) A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol (in press) PMC3595613 19465924
- Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, Wan X, Pavlidis P, Mills AA, Karayiorgou M, Gogos JA (2008) Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet 40: 751– 760 18469815
- Steward O (2002) mRNA at synapses, synaptic plasticity, and memory consolidation. Neuron 36: 338– 340 12408837
- Sutton MA, Schuman EM (2006) Dendritic protein synthesis, synaptic plasticity, and memory. Cell 127: 49– 58 17018276
- Tsang J, Zhu J, van Oudenaarden A (2007) MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell 26: 753– 767 17560377 PMC2072999
- Turrigiano G (2007) Homeostatic signaling: the positive side of negative feedback. Curr Opin Neurobiol 17: 318– 324 17451937
- Vessey JP, Vaccani A, Xie Y, Dahm R, Karra D, Kiebler MA, Macchi P (2006) Dendritic localization of the translational repressor Pumilio 2 and its contribution to dendritic stress granules. J Neurosci 26: 6496– 6508 16775137 PMC6674044
- Vo N, Klein ME, Varlamova O, Keller DM, Yamamoto T, Goodman RH, Impey S (2005) A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A 102: 16426– 16431 16260724 PMC1283476
- Waites CL, Craig AM, Garner CC (2005) Mechanisms of vertebrate synaptogenesis. Annu Rev Neurosci 28: 251– 274 16022596
- Wayman GA, Davare M, Ando H, Fortin D, Varlamova O, Cheng HY, Marks D, Obrietan K, Soderling TR, Goodman RH, Impey S (2008) An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc Natl Acad Sci USA 105: 9093– 9098 18577589 PMC2449370
- Whitford KL, Dijkhuizen P, Polleux F, Ghosh A (2002) Molecular control of cortical dendrite development. Annu Rev Neurosci 25: 127– 149 12052906
- Ye B, Petritsch C, Clark IE, Gavis ER, Jan LY, Jan YN (2004) Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr Biol 14: 314– 321 14972682
- Zhong J, Zhang T, Bloch LM (2006) Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neurons. BMC Neurosci 7: 17 16503994 PMC1386695
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Self-citation
- Authors
- Fiore, R., Khudayberdiev, S., Christensen, M., Siegel, G., Flavell, S. W., Kim, T., Greenberg, M. E., & Schratt, G.
- Venue
- The EMBO Journal
- Published
- 2009-02-05
- Volume
- 28
- Issue
- 6
- Pages
- 697-710
- ISSN
- 0261-4189
- 1460-2075
- PMC
- PMC2647767
- Cited by
- 348
- References
- 2
- Language
- en
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