Emerging role of microRNAs in major depressive disorder: diagnosis and therapeutic implications

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Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714 · see citing works

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States: Results From the National Comorbidity Survey

Kessler, R. C. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010008002 · Cited by 12,370 · see citing works

The functions of animal microRNAs

Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728 · see citing works

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., Guo, J., Zhang, Y., Chen, J., Guo, X., et al. (2008) · Cell Research · doi:10.1038/cr.2008.282 · Cited by 4,560 · see citing works

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing

Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., Pfeffer, S., Rice, A., Kamphorst, A. O., Landthaler, M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.04.040 · Cited by 3,626 · see citing works

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

Arroyo, J. D., Chevillet, J. R., Kroh, E. M., Ruf, I. K., Pritchard, C. C., Gibson, D. F., Mitchell, P. S., Bennett, C. F., Pogosova-Agadjanyan, E. L., Stirewalt, D. L., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019055108 · Cited by 3,294 · see citing works

Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00809-6 · Cited by 2,859 · see citing works

Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation

Vasudevan, S., Tong, Y., & STEITZ, J. A. (2007) · Science · doi:10.1126/science.1149460 · Cited by 2,806 · see citing works

The MicroRNA Spectrum in 12 Body Fluids

Weber, J. A., Baxter, D. H., Zhang, S., Huang, D. Y. C., Huang, K., Lee, M., Galas, D. J., & Wang, K. (2010) · Clinical Chemistry · doi:10.1373/clinchem.2010.147405 · Cited by 2,754 · see citing works

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

Vickers, K. C., Palmisano, B. T., Shoucri, B. M., Shamburek, R. D., & Remaley, A. T. (2011) · Nature Cell Biology · doi:10.1038/ncb2210 · Cited by 2,741 · see citing works

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

Chendrimada, T. P., Gregory, R. I., Kumaraswamy, E., Norman, J. A., Cooch, N. S., Nishikura, K., & Shiekhattar, R. (2005) · Nature · doi:10.1038/nature03868 · Cited by 2,103 · see citing works

A brain-specific microRNA regulates dendritic spine development

Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., & Greenberg, M. E. (2006) · Nature · doi:10.1038/nature04367 · Cited by 1,786 · see citing works

MicroRNAs in Stress Signaling and Human Disease

Mendell, J. T., & Olson, E. N. (2012) · Cell · doi:10.1016/j.cell.2012.02.005 · Cited by 1,673 · see citing works

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., & Ambros, V. (2004) · Genome Biology · doi:10.1186/gb-2004-5-3-r13 · Cited by 1,578 · see citing works

Glial reduction in the subgenual prefrontal cortex in mood disorders

Öngür, D., Drevets, W. C., & Price, J. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13290 · Cited by 1,525 · see citing works

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

Snyder, J. S., Soumier, A., Brewer, M., Pickel, J., & Cameron, H. A. (2011) · Nature · doi:10.1038/nature10287 · Cited by 1,473 · see citing works

MicroRNAs in body fluids—the mix of hormones and biomarkers

Cortez, M. A., Bueso-Ramos, C., Ferdin, J., Lopez‐Berestein, G., Sood, A. K., & Călin, G. A. (2011) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2011.76 · Cited by 1,471 · see citing works

Depression, Disability Days, and Days Lost From Work in a Prospective Epidemiologic Survey

Broadhead, W. E. (1990) · JAMA · doi:10.1001/jama.1990.03450190056028 · Cited by 1,232 · see citing works

Circulating MicroRNAs in Patients With Coronary Artery Disease

Fichtlscherer, S., Rosa, S. D., Fox, H., Schwietz, T., Fischer, A., Liebetrau, C., Weber, M. A., Hamm, C. W., Roexe, T., Müller-Ardogan, M., et al. (2010) · Circulation Research · doi:10.1161/circresaha.109.215566 · Cited by 1,222 · see citing works

Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment

Pariante, C. M., & Miller, A. H. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01088-x · Cited by 1,147 · see citing works

MicroRNAs direct rapid deadenylation of mRNA

Wu, L., Fan, J., & Belasco, J. G. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510928103 · Cited by 1,135 · see citing works

The majority of microRNAs detectable in serum and saliva is concentrated in exosomes

Gallo, A., Tandon, M., Alevizos, I., & Illei, G. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030679 · Cited by 1,060 · see citing works

Export of microRNAs and microRNA-protective protein by mammalian cells

Wang, K., Zhang, S., Weber, J., Baxter, D., & Galas, D. J. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq601 · Cited by 1,002 · see citing works

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

Gao, J., Wang, W.-Y., Mao, Y.-W., Gräff, J., Guan, J.-S., Pan, L., Mak, G., Kim, D., Su, S. C., & Tsai, L.-H. (2010) · Nature · doi:10.1038/nature09271 · Cited by 975 · see citing works

LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite

Toni, N., Buchs, P.-A., Nikonenko, I., Bron, C. R., & Muller, D. (1999) · Nature · doi:10.1038/46574 · Cited by 949 · see citing works

Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways

Cogswell, J. P., Ward, J., Taylor, I. A., Waters, M., Shi, Y., Cannon, B., Kelnar, K., Kemppainen, J., Brown, D., Chen, C., et al. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-14103 · Cited by 943 · see citing works

Altered Gene Expression of Brain-Derived Neurotrophic Factor and Receptor Tyrosine Kinase B in Postmortem Brain of Suicide Subjects

Dwivedi, Y., Rizavi, H. S., Conley, R. R., Roberts, R. C., Tamminga, C. A., & Pandey, G. N. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.8.804 · Cited by 875 · see citing works

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

Cheng, L.-C., Pastrana, E., Tavazoie, M., & Doetsch, F. (2009) · Nature Neuroscience · doi:10.1038/nn.2294 · Cited by 865 · see citing works

The neuronal microRNA system

Kosik, K. S. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn2037 · Cited by 823 · see citing works

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

Vo, N., Klein, M. E., Varlamova, O., Keller, D. M., Yamamoto, T. S., Goodman, R. H., & Impey, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508448102 · Cited by 799 · see citing works

DEFINITION AND EPIDEMIOLOGY OF TREATMENT-RESISTANT DEPRESSION

Fava, M., & Davidson, K. G. (1996) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70283-5 · Cited by 797 · see citing works

Reduced Glial Cell Density and Neuronal Size in the Anterior Cingulate Cortex in Major Depressive Disorder

Cotter, D., Mackay, D., Landau, S., Kerwin, R., & Everall, I. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.6.545 · Cited by 766 · see citing works

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

Edbauer, D., Neilson, J. R., Foster, K. A., Wang, C.-F., Seeburg, D. P., Batterton, M. N., Tada, T., Dolan, B. M., Sharp, P. A., & Sheng, M. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.005 · Cited by 735 · see citing works

Regulation of miRNA expression during neural cell specification

Smirnova, L., Gräfe, A., Seiler, A., Schumacher, S., Nitsch, R., & Wulczyn, F. G. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03978.x · Cited by 707 · see citing works

Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol

Mullauer, F. B., Kessler, J. H., & Medema, J. P. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005361 · Cited by 688 · see citing works

Epigenetics and MicroRNAs

Chuang, J. C., & Jones, P. A. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e3180457684 · Cited by 674 · see citing works

Revisiting the principles of microRNA target recognition and mode of action

Brodersen, P., & Voinnet, O. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2619 · Cited by 657 · see citing works

Microarray analysis of microRNA expression in the developing mammalian brain

Miska, E. A., Alvarez-Saavedra, E., Townsend, M., Yoshii, A., Šestan, N., Rakic, P., Constantine-Paton, M., & Horvitz, H. R. (2004) · Genome Biology · doi:10.1186/gb-2004-5-9-r68 · Cited by 651 · see citing works

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

Stark, K. L., Xu, B., Bagchi, A., Lai, W.-S., Liu, H., Hsu, R., Wan, X., Pavlidis, P., Mills, A. A., Karayiorgou, M., et al. (2008) · Nature Genetics · doi:10.1038/ng.138 · Cited by 648 · see citing works

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

Weiler, I. J., Irwin, S. A., Klintsova, A. Y., Spencer, C. M., Brazelton, A. D., Miyashiro, K., Comery, T. A., Patel, B., Eberwine, J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5395 · Cited by 644 · see citing works

Reciprocal actions of REST and a microRNA promote neuronal identity

Conaco, C., Otto, S., Han, J.-J., & Mandel, G. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511041103 · Cited by 641 · see citing works

Effects of adverse experiences for brain structure and function

McEwen, B. S. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00964-1 · Cited by 639 · see citing works

A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer

Hanke, M., Hoefig, K. P., Merz, H., Feller, A. C., Kausch, I., Jocham, D., Warnecke, J. M., & Sczakiel, G. (2009) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2009.01.027 · Cited by 638 · see citing works

MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F

Mathonnet, G., Fabian, M., Svitkin, Y., Parsyan, A., Huck, L., Murata, T., Biffo, S., Merrick, W., Darżynkiewicz, E., Pillai, R., et al. (2007) · Science · doi:10.1126/science.1146067 · Cited by 636 · see citing works

Gliogenesis and Glial Pathology in Depression

Rajkowska, G., & Miguel-Hidalgo, J. J. (2007) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152707780619326 · Cited by 612 · see citing works

Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway

Jin, P., Zarnescu, D. C., Ceman, S., Nakamoto, M., Mowrey, J., Jongens, T. A., Nelson, D. L., Moses, K., & Warren, S. T. (2004) · Nature Neuroscience · doi:10.1038/nn1174 · Cited by 604 · see citing works

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

Dupret, D., Revest, J., Koehl, M., Ichas, F., Giorgi, F. D., Costet, P., Abrous, D. N., & Piazza, P. V. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001959 · Cited by 595 · see citing works

MicroRNAs and epigenetics

Sato, F., Tsuchiya, S., Meltzer, S. J., & Shimizu, K. (2011) · FEBS Journal · doi:10.1111/j.1742-4658.2011.08089.x · Cited by 586 · see citing works

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

Wayman, G. A., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, H.-Y. M., Marks, D., Obrietan, K., Soderling, T. R., Goodman, R. H., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803072105 · Cited by 559 · see citing works

The role of profilin complexes in cell motility and other cellular processes

Witke, W. (2004) · Trends in Cell Biology · doi:10.1016/j.tcb.2004.07.003 · Cited by 529 · see citing works

Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors

Ju, W. H., Morishita, W., Tsui, J., Gaietta, G. M., Deerinck, T. J., Adams, S., Garner, C. C., Tsien, R. Y., Ellisman, M. H., & Malenka, R. C. (2004) · Nature Neuroscience · doi:10.1038/nn1189 · Cited by 524 · see citing works

Antidepressants and neuroplasticity

D'Sa, C. M., & Duman, R. S. (2002) · Bipolar Disorders · doi:10.1034/j.1399-5618.2002.01203.x · Cited by 516 · see citing works

Depression and Hippocampal Neurogenesis: A Road to Remission?

Eisch, A. J., & Petrik, D. (2012) · Science · doi:10.1126/science.1222941 · Cited by 516 · see citing works

A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome

Dictenberg, J. B., Swanger, S. A., Antar, L. N., Singer, R. H., & Bassell, G. J. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.04.003 · Cited by 511 · see citing works

MicroRNA silencing through RISC recruitment of eIF6

Chendrimada, T. P., Finn, K. J., Ji, X., Baillat, D., Gregory, R. I., Liebhaber, S. A., Pasquinelli, A. E., & Shiekhattar, R. (2007) · Nature · doi:10.1038/nature05841 · Cited by 509 · see citing works

Fragile X-related protein and VIG associate with the RNA interference machinery

Caudy, A. A., Myers, M., Hannon, G. J., & Hammond, S. M. (2002) · Genes & Development · doi:10.1101/gad.1025202 · Cited by 499 · see citing works

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

Szulwach, K. E., Li, X., Smrt, R. D., Li, Y., Luo, Y., Lin, L., Santistevan, N. J., Li, W., Zhao, X., & Jin, P. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200908151 · Cited by 493 · see citing works

A <i>Drosophila</i> fragile X protein interacts with components of RNAi and ribosomal proteins

Ishizuka, A., Siomi, M. C., & Siomi, H. (2002) · Genes &amp; Development · doi:10.1101/gad.1022002 · Cited by 486 · see citing works

3D MRI studies of neuroanatomic changes in unipolar major depression: the role of stress and medical comorbidity

Sheline, Y. I. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00994-x · Cited by 485 · see citing works

MiR-16 Targets the Serotonin Transporter: A New Facet for Adaptive Responses to Antidepressants

Baudry, A., Mouillet-Richard, S., Schneider, B., Launay, J.-M., & Kellermann, O. (2010) · Science · doi:10.1126/science.1193692 · Cited by 480 · see citing works

MicroRNA expression in the adult mouse central nervous system

Bak, M., Silahtaroglu, A., Møller, M., Christensen, M., Rath, M. F., Skryabin, B., Tommerup, N., & Kauppinen, S. (2008) · RNA · doi:10.1261/rna.783108 · Cited by 463 · see citing works

Linking Mind and Brain in the Study of Mental Illnesses: A Project for a Scientific Psychopathology

Andreasen, N. C. (1997) · Science · doi:10.1126/science.275.5306.1586 · Cited by 451 · see citing works

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action☆

Lucassen, P. J., Meerlo, P., Naylor, A. S., van Dam, A. M., Dayer, A. G., Fuchs, E., Oomen, C. A., & Czéh, B. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2009.08.003 · Cited by 449 · see citing works

Synaptic Protein Synthesis Associated with Memory Is Regulated by the RISC Pathway in Drosophila

Ashraf, S. I., McLoon, A. L., Sclarsic, S. M., & Kunes, S. M. (2006) · Cell · doi:10.1016/j.cell.2005.12.017 · Cited by 446 · see citing works

The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members

Farazi, T. A., Juranek, S., & Tuschl, T. (2008) · Development · doi:10.1242/dev.005629 · Cited by 428 · see citing works

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

Siegel, G., Obernosterer, G., Fiore, R., Oehmen, M., Bicker, S., Christensen, M., Khudayberdiev, S., Leuschner, P. F., Busch, C. J. L., Kane, C., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1876 · Cited by 427 · see citing works

Cerebellar neurodegeneration in the absence of microRNAs

Schaefer, A., O'Carroll, D., Tan, C. L., Hillman, D., Sugimori, M., Llinas, R., & Greengard, P. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070823 · Cited by 426 · see citing works

Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB

Rajasethupathy, P., Fiumara, F., Sheridan, R., Betel, D., Puthanveettil, S. V., Russo, J. J., Sander, C., Tuschl, T., & Kandel, E. (2009) · Neuron · doi:10.1016/j.neuron.2009.05.029 · Cited by 406 · see citing works

MicroRNAs in neuronal function and dysfunction

Im, H.-I., & Kenny, P. J. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.01.004 · Cited by 399 · see citing works

Exosomes as Intercellular Signaling Organelles Involved in Health and Disease: Basic Science and Clinical Applications

Corrado, C., Raimondo, S., Chiesi, A., Ciccia, F., de Leo, G., & Alessandro, R. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms14035338 · Cited by 395 · see citing works

When neurogenesis encounters aging and disease

Lazarov, O., Mattson, M. P., Peterson, D. A., Pimplikar, S. W., & van Praag, H. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.09.003 · Cited by 389 · see citing works

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

Davis, T. H., Cuellar, T. L., Koch, S. M., Barker, A. J., Harfe, B. D., McManus, M. T., & Ullian, E. M. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4815-07.2008 · Cited by 384 · see citing works

Identification of forensically relevant body fluids using a panel of differentially expressed microRNAs

Hanson, E., Lubenow, H., & Ballantyne, J. (2009) · Analytical Biochemistry · doi:10.1016/j.ab.2009.01.037 · Cited by 379 · see citing works

MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system

Kapsimali, M., Kloosterman, W. P., de Bruijn, E., Rosa, F., Plasterk, R. H., & Wilson, S. W. (2007) · Genome Biology · doi:10.1186/gb-2007-8-8-r173 · Cited by 376 · see citing works

Mef2‐mediated transcription of the miR379–410 cluster regulates activity‐dependent dendritogenesis by fine‐tuning Pumilio2 protein levels

Fiore, R., Khudayberdiev, S., Christensen, M., Siegel, G., Flavell, S. W., Kim, T., Greenberg, M. E., & Schratt, G. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.10 · Cited by 348 · see citing works

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

De Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Hannon, G. J., & Huttner, W. B. (2008) · Development · doi:10.1242/dev.025080 · Cited by 343 · see citing works

Reduced activation and expression of ERK1/2 MAP kinase in the post‐mortem brain of depressed suicide subjects

Dwivedi, Y., Rizavi, H. S., Roberts, R. C., Conley, R. C., Tamminga, C. A., & Pandey, G. N. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00300.x · Cited by 333 · see citing works

Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics

Kalani, A., Tyagi, A. A., & Tyagi, N. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8544-1 · Cited by 333 · see citing works

MicroRNA Expression Is Down-Regulated and Reorganized in Prefrontal Cortex of Depressed Suicide Subjects

Smalheiser, N. R., Lugli, G., Rizavi, H. S., Torvik, V. I., Turecki, G., & Dwivedi, Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033201 · Cited by 324 · see citing works

Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents

Uchida, S., Hara, K., Kobayashi, A., Funato, H., Hobara, T., Otsuki, K., Yamagata, H., McEwen, B. S., & Watanabe, Y. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1436-10.2010 · Cited by 310 · see citing works

MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

Yu, J., Chung, K.-H., Deo, M., Thompson, R. C., & Turner, D. L. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.06.002 · Cited by 310 · see citing works

MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders

Kim, A. H., Reimers, M., Maher, B., Williamson, V., McMichael, O., McClay, J. L., van den Oord, E. J. C. G., Riley, B. P., Kendler, K. S., & Vladimirov, V. I. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.07.002 · Cited by 298 · see citing works

Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay

Bruno, I., Karam, R., Huang, L., Bhardwaj, A., Lou, C. H., Shum, E. Y., Song, H.-W., Corbett, M. A., Gifford, W. D., Gécz, J., et al. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.04.018 · Cited by 291 · see citing works

Depression, disability days, and days lost from work in a prospective epidemiologic survey

Broadhead, W. E. (1990) · JAMA · doi:10.1001/jama.264.19.2524 · Cited by 289 · see citing works

The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95

Todd, P. K., Mack, K. J., & Malter, J. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2336265100 · Cited by 280 · see citing works

Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain

He, M., Liu, Y., Wang, X., Zhang, M. Q., Hannon, G. J., & Huang, Z. J. (2012) · Neuron · doi:10.1016/j.neuron.2011.11.010 · Cited by 277 · see citing works

MiRNA–miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features

Xu, J., Li, C., Li, Y.-S., Lv, J., Ma, Y., Shao, T.-T., Xu, L., Wang, Y.-Y., Du, L., Zhang, Y. P., et al. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq832 · Cited by 275 · see citing works

An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling

Impey, S., Davare, M., Lasiek, A., Fortin, D., Ando, H., Varlamova, O., Obrietan, K., Soderling, T. R., Goodman, R. H., & Wayman, G. A. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2009.10.005 · Cited by 270 · see citing works

Differential coexpression analysis using microarray data and its application to human cancer

Choi, J. K., Yu, U., Yoo, O. J., & Kim, S. (2005) · Bioinformatics · doi:10.1093/bioinformatics/bti722 · Cited by 265 · see citing works

Olfactory Discrimination Learning Increases the Survival of Adult-Born Neurons in the Olfactory Bulb

Alonso, M., Viollet, C., Gabellec, M., Meas‐Yedid, V., Olivo‐Marín, J., & Lledo, P. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2633-06.2006 · Cited by 263 · see citing works

Dorsolateral prefrontal cortex dysfunction in the major psychoses; symptom or disease specificity?

Dolan, R. J., Bench, C. J., Liddle, P. F., Friston, K. J., Frith, C. D., Grasby, P. M., & Frackowiak, R. S. (1993) · Journal of Neurology, Neurosurgery &amp; Psychiatry · doi:10.1136/jnnp.56.12.1290 · Cited by 261 · see citing works

MicroRNA 18 and 124a Down-Regulate the Glucocorticoid Receptor: Implications for Glucocorticoid Responsiveness in the Brain

Vreugdenhil, E., Veríssimo, C. S., Mariman, R., Kamphorst, J. T., Barbosa, J. S., Zweers, T. J., Champagne, D. L., Schouten, T. G., Meijer, O. C., de Kloet, E. R., et al. (2009) · Endocrinology · doi:10.1210/en.2008-1335 · Cited by 260 · see citing works

Hippocampal neurogenesis as a target for the treatment of mental illness: A critical evaluation

DeCarolis, N. A., & Eisch, A. J. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.12.013 · Cited by 252 · see citing works

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing

Azuma-Mukai, A., Oguri, H., Mitsuyama, T., Qian, Z. R., Asai, K., Siomi, H., & Siomi, M. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800334105 · Cited by 249 · see citing works

Members of the miRNA-200 Family Regulate Olfactory Neurogenesis

Choi, P. S., Zakhary, L., Choi, W.-Y., Caron, S. J. C., Alvarez-Saavedra, E., Miska, E. A., McManus, M. T., Harfe, B. D., Giráldez, A. J., Horvitz, H. R., et al. (2008) · Neuron · doi:10.1016/j.neuron.2007.11.018 · Cited by 245 · see citing works

Short‐term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus

Hajszán, T., MacLusky, N. J., & Leranth, C. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03968.x · Cited by 239 · see citing works

Chapter 8 Synaptic plasticity in learning and memory: Stress effects in the hippocampus

Howland, J. G., & Wang, Y. T. (2008) · Progress in brain research · doi:10.1016/s0079-6123(07)00008-8 · Cited by 238 · see citing works

Blood microRNA changes in depressed patients during antidepressant treatment

Bocchio-Chiavetto, L., Maffioletti, E., Bettinsoli, P., Giovannini, C., Bignotti, S., Tardito, D., Corrada, D., Milanesi, L., & Gennarelli, M. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.06.013 · Cited by 238 · see citing works

Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain

Lugli, G., Torvik, V. I., Larson, J., & Smalheiser, N. R. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05413.x · Cited by 228 · see citing works

A Coordinated Local Translational Control Point at the Synapse Involving Relief from Silencing and MOV10 Degradation

Banerjee, S., Neveu, P. A., & Kosik, K. S. (2009) · Neuron · doi:10.1016/j.neuron.2009.11.023 · Cited by 227 · see citing works

A New Binding Motif for the Transcriptional Repressor REST Uncovers Large Gene Networks Devoted to Neuronal Functions

Otto, S. J., McCorkle, S., Hover, J., Conaco, C., Han, J., Impey, S., Yochum, G. S., Dunn, J. J., Goodman, R. H., & Mandel, G. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0091-07.2007 · Cited by 226 · see citing works

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

Zeng, Y., Sankala, H. M., Zhang, X., & Graves, P. R. (2008) · Biochemical Journal · doi:10.1042/bj20080599 · Cited by 225 · see citing works

Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner

Lugli, G., Larson, J., Martone, M. E., Jones, Y., & Smalheiser, N. R. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03224.x · Cited by 222 · see citing works

Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode

Belzeaux-R, R., Bergon, A., Jeanjean, V., Loriod, B., Formisano‐Tréziny, C., Verrier, L., Loundou, A., Baumstarck, K., Boyer, L., Gall, V., et al. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.112 · Cited by 222 · see citing works

Comparative sequence analysis reveals an intricate network among REST, CREBand miRNA in mediating neuronal gene expression

Wu, J., & Xie, X. (2006) · Genome Biology · doi:10.1186/gb-2006-7-9-r85 · Cited by 221 · see citing works

MicroRNA networks direct neuronal development and plasticity

Loohuis, N. F. M. O., Kos, A., Martens, G. J. M., van Bokhoven, H., Kasri, N. N., & Aschrafi, A. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0788-1 · Cited by 220 · see citing works

MicroRNA regulation of homeostatic synaptic plasticity

Cohen, J. E., Lee, P. R., Chen, S., Li, W., & Fields, R. D. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017576108 · Cited by 214 · see citing works

MicroRNA-124 is a subventricular zone neuronal fate determinant

Akerblom, M., Sachdeva, R., Barde, I., Verp, S., Gentner, B., Trono, D., & Jakobsson, J. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0558-12.2012 · Cited by 207 · see citing works

Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA‐mediated down‐regulation of the glucocorticoid receptor

Uchida, S., Nishida, A., Hara, K., Kamemoto, T., Suetsugi, M., Fujimoto, M., Watanuki, T., Wakabayashi, Y., Otsuki, K., McEwen, B. S., et al. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06218.x · Cited by 203 · see citing works

Changes in Brain MicroRNAs Contribute to Cholinergic Stress Reactions

Meerson, A., Cacheaux, L. P., Goosens, K. A., Sapolsky, R. M., Soreq, H., & Kaufer, D. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-009-9252-1 · Cited by 203 · see citing works

MicroRNA function in neuronal development, plasticity and disease

Fiore, R., Siegel, G., & Schratt, G. M. (2007) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2007.12.006 · Cited by 202 · see citing works

Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression

Kawashima, H., Numakawa, T., Kumamaru, E., Adachi, N., Mizuno, H., Ninomiya, M., Kunugi, H., & Hashido, K. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.11.057 · Cited by 200 · see citing works

Abnormal Hippocampal BDNF and miR-16 Expression Is Associated with Depression-Like Behaviors Induced by Stress during Early Life

Bai, M., Zhu, X., Zhang, Y., Zhang, S., Zhang, L., Xue, L., Yi, J., Yao, S., & Zhang, X. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046921 · Cited by 195 · see citing works

MicroRNA-134 plasma levels before and after treatment for bipolar mania

Rong, H., Liu, T. B., Yang, K. J., Yang, H. C., Wu, D., Liao, C.-P., Hong, F., Yang, H. Z., Wan, F., Ye, X. Y., et al. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.04.028 · Cited by 189 · see citing works

Local translational control in dendrites and its role in long‐term synaptic plasticity

Sutton, M. A., & Schuman, E. M. (2005) · Journal of Neurobiology · doi:10.1002/neu.20152 · Cited by 188 · see citing works

Identification and quantitative analyses of microRNAs located in the distal axons of sympathetic neurons

Natera-Naranjo, O., Aschrafi, A., Gioio, A. E., & Kaplan, B. B. (2010) · RNA · doi:10.1261/rna.1833310 · Cited by 180 · see citing works

Characterization of endogenous human argonautes and their miRNA partners in RNA silencing

向井, あ., & 東, あ. (2008) · Medical Entomology and Zoology · Cited by 179 · see citing works

Abnormal Expression and Functional Characteristics of Cyclic Adenosine Monophosphate Response Element Binding Protein in Postmortem Brain of Suicide Subjects

Dwivedi, Y., Rao, J. S., Rizavi, H. S., Kotowski, J., Conley, R. R., Roberts, R. C., Tamminga, C. A., & Pandey, G. N. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.3.273 · Cited by 177 · see citing works

Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease.

Gaughwin, P., Cieśla, M., Lahiri, N., Tabrizi, S., Brundin, P., & Björkqvist, M. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr111 · Cited by 174 · see citing works

Stress and hippocampal abnormalities in psychiatric disorders

Sala, M. (2004) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2003.12.005 · Cited by 169 · see citing works

Stress induces region specific alterations in microRNAs expression in mice

Rinaldi, A., Vincenti, S., Vito, F. D., Bozzoni, I., Oliverio, A., Presutti, C., Fragapane, P., & Mele, A. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.11.012 · Cited by 162 · see citing works

Patterns of memory impairment in bipolar disorder and unipolar major depression

Bearden, C. E., Glahn, D. C., Monkul, E. S., Barrett, J., Najt, P., Villarreal, V., & Soares, J. C. (2006) · Psychiatry Research · doi:10.1016/j.psychres.2005.08.010 · Cited by 162 · see citing works

miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

Mellios, N., Sugihara, H., Castro, J., Banerjee, A., Le, C., Kumar, A., Crawford, B., Strathmann, J., Tropea, D., Levine, S. S., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2909 · Cited by 161 · see citing works

Fine-tuning neural gene expression with microRNAs

Schratt, G. M. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.05.015 · Cited by 159 · see citing works

Reduced Adult Hippocampal Neurogenesis and Working Memory Deficits in the<i>Dgcr8</i>-Deficient Mouse Model of 22q11.2 Deletion-Associated Schizophrenia Can Be Rescued by IGF2

Ouchi, Y., Banno, Y., Shimizu, Y., Ando, S., Hasegawa, H., Adachi, K., & Iwamoto, T. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.2700-12.2013 · Cited by 155 · see citing works

Transcriptional control of the glucocorticoid receptor: CpG islands, epigenetics and more

Turner, J. D., Alt, S. R., Cao, L., Vernocchi, S., Trifonova, S. T., Battello, N., & Muller, C. P. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.06.037 · Cited by 145 · see citing works

Cingulate cortex synaptic terminal proteins and neural cell adhesion molecule in schizophrenia

Honer, W. G., Falkai, P., Young, C., Wang, T., Xie, J., Bonner, J., Hu, L., Boulianne, G. L., Luo, Z., & Trimble, W. S. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00489-7 · Cited by 144 · see citing works

Aberrant expression of serum miRNAs in schizophrenia

Shi, W., Du, J., Qi, Y., Liang, G., Wang, T., Li, S., Xie, S., Zeshan, B., & Xiao, Z. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.09.010 · Cited by 143 · see citing works

Micro-RNAs (miRNAs): genomic organisation, biogenesis and mode of action

Hussain, M. U. (2012) · Cell and Tissue Research · doi:10.1007/s00441-012-1438-0 · Cited by 133 · see citing works

From microRNA functions to microRNA therapeutics: Novel targets and novel drugs in breast cancer research and treatment

Piva, R., Spandidos, D. A., & Gambari, R. (2013) · International Journal of Oncology · doi:10.3892/ijo.2013.2059 · Cited by 129 · see citing works

MicroRNA‐132 regulates recognition memory and synaptic plasticity in the perirhinal cortex

Scott, H. L., Tamagnini, F., Narduzzo, K. E., Howarth, J. L., Lee, Y., Wong, L., Brown, M. W., Warburton, E. C., Bashir, Z. I., & Uney, J. B. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08220.x · Cited by 128 · see citing works

miR-132 Enhances Dendritic Morphogenesis, Spine Density, Synaptic Integration, and Survival of Newborn Olfactory Bulb Neurons

Pathania, M., Torres-Reveron, J., Yan, L. D., Kimura, T., Lin, T. V., Gordon, V., Teng, Z., Zhao, X., Fulga, T. A., Vactor, D. V., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038174 · Cited by 128 · see citing works

Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase

Meng, Y., Takahashi, H., Meng, J., Zhang, Y., Lu, G., Asrar, S., Nakamura, T., & Jia, Z. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.030 · Cited by 127 · see citing works

Brain Derived Neurotrophic Factor (BDNF) Expression Is Regulated by MicroRNAs miR-26a and miR-26b Allele-Specific Binding

Caputo, V., Sinibaldi, L., Fiorentino, A., Parisi, C., Catalanotto, C., Pasini, A., Cogoni, C., & Pizzuti, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028656 · Cited by 126 · see citing works

ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf

Dwivedi, Y., Rizavi, H. S., Conley, R. R., & Pandey, G. N. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001744 · Cited by 123 · see citing works

The emerging role of microRNAs in schizophrenia and autism spectrum disorders

Mellios, N., & Sur, M. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00039 · Cited by 120 · see citing works

Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16

Launay, J., Mouillet‐Richard, S., Baudry, A., Pietri, M., & Kellermann, O. (2011) · Translational Psychiatry · doi:10.1038/tp.2011.54 · Cited by 118 · see citing works

MicroRNA expression in rat brain exposed to repeated inescapable shock: differential alterations in learned helplessness vs. non-learned helplessness

Smalheiser, N. R., Lugli, G., Rizavi, H. S., Zhang, H., Torvik, V. I., Pandey, G. N., Davis, J. M., & Dwivedi, Y. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145710001628 · Cited by 115 · see citing works

The clinical potential of microRNAs

Budhu, A., Ji, J., & Wang, X. W. (2010) · Journal of Hematology & Oncology · doi:10.1186/1756-8722-3-37 · Cited by 110 · see citing works

Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders

Jun, H., Hussaini, S. M. Q., Rigby, M. J., & Jang, M. (2012) · Neural Plasticity · doi:10.1155/2012/854285 · Cited by 109 · see citing works

MicroRNAs Show Mutually Exclusive Expression Patterns in the Brain of Adult Male Rats

Olsen, L., Klausen, M., Helboe, L., Nielsen, F. C., & Werge, T. M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007225 · Cited by 107 · see citing works

Evidence demonstrating role of microRNAs in the etiopathology of major depression

Dwivedi, Y. (2011) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2011.04.002 · Cited by 107 · see citing works

Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway

Matigian, N., Windus, L. C. E., Smith, H., Filippich, C., Pantelis, C., McGrath, J. J., Mowry, B. J., & Hayward, N. K. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001998 · Cited by 106 · see citing works

Maternal separation and social isolation modulate the postnatal development of synaptic composition in the infralimbic cortex of Octodon degus

Ovtscharoff, W. A., & Braun, K. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00059-8 · Cited by 103 · see citing works

microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus

O'Connor, R. M., Grenham, S., Dinan, T. G., & Cryan, J. F. (2013) · International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000448 · Cited by 101 · see citing works

Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: Role of ERK kinase 1 (MEK1)

Dwivedi, Y., Rizavi, H. S., Zhang, H., Roberts, R. C., Conley, R. R., & Pandey, G. N. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709990575 · Cited by 101 · see citing works

Histopathology of the prefrontal cortex in major depression: what does it tell us about dysfunctional monoaminergic circuits?

Rajkowska, G. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)26026-3 · Cited by 99 · see citing works

Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders

Serafini, G., Pompili, M., Innamorati, M., Fusar‐Poli, P., Akiskal, H. S., Rihmer, Z., Lester, D., Romano, A., de Oliveira, I. R., Strusi, L., et al. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.07.020 · Cited by 98 · see citing works

Identification of forensically relevant body fluids using a panel of differentially expressed microRNAs

Hanson, E., Lubenow, H., & Ballantyne, J. (2009) · Forensic science international. Genetics supplement series · doi:10.1016/j.fsigss.2009.08.184 · Cited by 97 · see citing works

Epigenetic Risk Factors in PTSD and Depression

Raabe, F. J., & Spengler, D. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00080 · Cited by 94 · see citing works

Environmental and pharmacological modulations of cellular plasticity: Role in the pathophysiology and treatment of depression

Ota, K. T., & Duman, R. S. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.05.022 · Cited by 94 · see citing works

Psychometric properties of the Gotland Scale for Depression in Italian psychiatric inpatients and its utility in the prediction of suicide risk

Innamorati, M., Pompili, M., Gonda, X., Amore, M., Serafini, G., Niolu, C., Lester, D., Rutz, W., Rihmer, Z., & Girardi, P. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.02.003 · Cited by 93 · see citing works

Reduced glucose metabolism in the subgenual prefrontal cortex in unipolar depression

Drevets, W. C., Öngür, D., & Price, J. (1998) · Molecular Psychiatry · doi:10.1038/sj.mp.4000380 · Cited by 92 · see citing works

Cyclothymic–depressive–anxious temperament pattern is related to suicide risk in 346 patients with major mood disorders

Pompili, M., Innamorati, M., Rihmer, Z., Gonda, X., Serafini, G., Akiskal, H. H., Amore, M., Niolu, C., Sher, L., Tatarelli, R., et al. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.11.011 · Cited by 91 · see citing works

Dynamic Roles of microRNAs in Neurogenesis

Lang, M., & Shi, Y. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00071 · Cited by 90 · see citing works

MicroRNAs in Adult and Embryonic Neurogenesis

Liu, C., & Zhao, X. (2009) · NeuroMolecular Medicine · doi:10.1007/s12017-009-8077-y · Cited by 85 · see citing works

The role of microRNAs in synaptic plasticity, major affective disorders and suicidal behavior

Serafini, G., Pompili, M., Innamorati, M., Giordano, G., Montebovi, F., Sher, L., Dwivedi, Y., & Girardi, P. (2012) · Neuroscience Research · doi:10.1016/j.neures.2012.04.001 · Cited by 80 · see citing works

Circulating microRNAs in Alzheimer’s disease: the search for novel biomarkers

Dorval, V., Nelson, P. T., & Hébert, S. S. (2013) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2013.00024 · Cited by 80 · see citing works

Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients

Saus, E., Brunet‐Vega, A., Armengol, L., Alonso, P., Crespo, J. M., Fernández‐Aranda, F., Guitart, M., Martín‐Santos, R., Menchón, J. M., Navinés, R., et al. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.03.007 · Cited by 79 · see citing works

Major Depression: A Role for Hippocampal Neurogenesis?

Lee, M. M., Reif, A., & Schmitt, A. G. (2012) · Current topics in behavioral neurosciences · doi:10.1007/7854_2012_226 · Cited by 75 · see citing works

Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis

McLoughlin, H. S., Fineberg, S. K., Ghosh, L., Tecedor, L., & Davidson, B. L. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.08.009 · Cited by 72 · see citing works

Genome-Wide miRNA Expression Profiling of Human Lymphoblastoid Cell Lines Identifies Tentative SSRI Antidepressant Response Biomarkers

Oved, K., Morag, A., Pasmanik-Chor, M., Oron-Karni, V., Shomron, N., Rehavi, M., Stingl, J. C., & Gurwitz, D. (2012) · Pharmacogenomics · doi:10.2217/pgs.12.93 · Cited by 66 · see citing works

Morphological Brain Changes in Depression: Can Antidepressants Reverse Them?

Miguel-Hidalgo, J. J., & Rajkowska, G. (2002) · CNS Drugs · doi:10.2165/00023210-200216060-00001 · Cited by 64 · see citing works

New Neurons in Aging Brains: Molecular Control by Small Non-Coding RNAs

Schouten, M., Buijink, M. R., Lucassen, P. J., & Fitzsimons, C. P. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00025 · Cited by 64 · see citing works

Non coding RNA and brain

Presutti, C., Rosati, J. D., Vincenti, S., & Nasi, S. (2006) · BMC Neuroscience · doi:10.1186/1471-2202-7-s1-s5 · Cited by 62 · see citing works

MicroRNAs in cancers and neurodegenerative disorders

Saito, Y., & Saito, H. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00194 · Cited by 62 · see citing works

Brain, networks, depression, and more

Leistedt, S., & Linkowski, P. (2012) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.10.011 · Cited by 62 · see citing works

New Therapeutic Targets for Mood Disorders

Machado‐Vieira, R., Salvadore, G., Diazgranados, N., Ibrahim, L. A., Latov, D. R., Wheeler‐Castillo, C., Baumann, J., Henter, I. D., & Zarate, C. A. (2010) · The Scientific World JOURNAL · doi:10.1100/tsw.2010.65 · Cited by 61 · see citing works

Structural plasticity: cause, result, or correlate of depression

Gage, F. H. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01019-2 · Cited by 61 · see citing works

Genome-wide Expression Profiling of Human Lymphoblastoid Cell Lines Identifies CHL1 as a Putative SSRI Antidepressant Response Biomarker

Morag, A., Pasmanik, M., Oron‐Karni, V., Rehavi, M., Stingl, J., & Gurwitz, D. (2011) · Pharmacogenomics · doi:10.2217/pgs.10.185 · Cited by 59 · see citing works

Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder

Schmidt, U., Herrmann, L., Hagl, K., Novak, B., Huber, C., Holsboer, F., Wotjak, C., & Buell, D. R. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00066 · Cited by 58 · see citing works

Local synthesis of axonal and presynaptic RNA in squid model systems

Eyman, M., Cefaliello, C., Ferrara, E., Stefano, R. D., Lavina, Z. S., Crispino, M., Squillace, A., van Minnen, J., Kaplan, B. B., & Giuditta, A. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05304.x · Cited by 56 · see citing works

MicroRNAs: Meta-controllers of gene expression in synaptic activity emerge as genetic and diagnostic markers of human disease

Ceman, S., & Saugstad, J. A. (2011) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.01.004 · Cited by 56 · see citing works

Briefing in family characteristics of microRNAs and their applications in cancer research

Wang, Q., Wei, L., Guan, X., Wu, Y., Zou, Q., & Ji, Z. (2013) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2013.08.002 · Cited by 52 · see citing works

Genetic Variations in MicroRNA Processing Genes Are Associated with Susceptibility in Depression

He, Y., Zhou, Y., Xi, Q., Cui, H., Luo, T., Song, H., Nie, X., Wang, L., & Ying, B. (2012) · DNA and Cell Biology · doi:10.1089/dna.2012.1660 · Cited by 52 · see citing works

The Path to microRNA Therapeutics in Psychiatric and Neurodegenerative Disorders

Chan, A. W. S., & Kocerha, J. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00082 · Cited by 51 · see citing works

RNA world – the dark matter of evolutionary genomics

Michalak, P. (2006) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2006.01141.x · Cited by 50 · see citing works

Morphometric analysis of synaptic contacts in the anterior limbic cortex in the endogenous psychoses

Aganova, �. A., & Uranova, N. A. (1992) · Neuroscience and Behavioral Physiology · doi:10.1007/bf01186670 · Cited by 49 · see citing works

Estradiol alters transcription factor gene expression in primate prefrontal cortex

Wang, J., Cheng, C. M., Zhou, J., Smith, A., Weickert, C. S., Perlman, W. R., Becker, K. G., Powell, D., & Bondy, C. A. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20076 · Cited by 47 · see citing works

Adult hippocampal neurogenesis: An actor in the antidepressant-like action

Mendez‐David, I., Hen, R., Gardier, A. M., & David, D. J. P. (2013) · Annales Pharmaceutiques Françaises · doi:10.1016/j.pharma.2013.02.006 · Cited by 46 · see citing works

Biomarker investigations related to pathophysiological pathways in schizophrenia and psychosis

Chana, G., Bousman, C., Money, T., Gibbons, A. S., Gillett, P., Dean, B., & Everall, I. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00095 · Cited by 44 · see citing works

Electroconvulsive stimulation alters levels of BDNF-associated microRNAs

Ryan, K. M., O'Donovan, S. M., & McLoughlin, D. M. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.05.035 · Cited by 42 · see citing works

Functional Brain Circuits in Major Depression and Remission

Sackeïm, H. A. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.7.649 · Cited by 41 · see citing works

Lost in translation. New unexplored avenues for neuropsychopharmacology: epigenetics and microRNAs

Tardito, D., Mallei, A., & Popoli, M. (2012) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2013.749237 · Cited by 37 · see citing works

Fine-tuning the brain: MicroRNAs

Vreugdenhil, E., & Berezikov, E. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.08.001 · Cited by 36 · see citing works

Cloning and Identification of Novel MicroRNAs from Rat Hippocampus

He, X., Zhang, Q., Liu, Y., & Pan, X.-Y. (2007) · Acta Biochimica et Biophysica Sinica · doi:10.1111/j.1745-7270.2007.00324.x · Cited by 36 · see citing works

Screening of specific microRNA in hippocampus of depression model rats and intervention effect of Chaihu Shugan San

Cao, M.-Q., Chen, D.-H., Zhang, C., & Wu, Z. (2013) · China Journal of Chinese Materia Medica · doi:10.4268/cjcmm201301027 · Cited by 36 · see citing works

EARLY SOCIAL ISOLATION DECREASES THE EXPRESSION OF CALBINDIN D-28K AND DENDRITIC BRANCHING IN THE MEDIAL PREFRONTAL CORTEX OF THE RAT

Pascual, R., Zamora-León, S. P., Catalán-Ahumada, M., & Valero‐Cabré, A. (2007) · International Journal of Neuroscience · doi:10.1080/00207450600773459 · Cited by 34 · see citing works

Impact of RNA interference on gene networks

Malphettes, L., & Fussenegger, M. (2006) · Metabolic Engineering · doi:10.1016/j.ymben.2006.07.005 · Cited by 31 · see citing works

Early life stress causes FG-7142-induced corticolimbic dysfunction in adulthood

Stevenson, C. W., Marsden, C. A., & Mason, R. (2008) · Brain Research · doi:10.1016/j.brainres.2007.11.062 · Cited by 29 · see citing works

Assessing the machinery of mind: synapses in neuropsychiatric disorders.

Honer, W. G. (1999) · PubMed · Cited by 26 · see citing works

Whole miRNome-Wide Differential Co-Expression of MicroRNAs

Stähler, C., Keller, A., Leidinger, P., Backes, C., Chandran, A., Wischhusen, J., Meder, B., & Meese, E. U. (2012) · Genomics Proteomics & Bioinformatics · doi:10.1016/j.gpb.2012.08.003 · Cited by 22 · see citing works

Role of microRNA Pathway in Mental Retardation

Qurashi, A., Chang, S., & Jin, P. (2007) · The Scientific World JOURNAL · doi:10.1100/tsw.2007.208 · Cited by 21 · see citing works

Novel Cerebellum-Enriched miR-592 May Play a Role in Neural Progenitor Cell Differentiation and Neuronal Maturation Through Regulating Lrrc4c and Nfasc in Rat

Zhang, J., Zhang, J., Zhou, Y., Wu, Y., Ma, L., Wang, R., Huang, S., Gao, R., Liu, L., Shao, Z., et al. (2013) · Current Molecular Medicine · doi:10.2174/15665240113139990072 · Cited by 20 · see citing works

Synaptic enrichment of microRNAs in adult mouse forebrain is related to structural features of their precursors

Smalheiser, N. R. (2008) · Biology Direct · doi:10.1186/1745-6150-3-44 · Cited by 20 · see citing works

A stochastic model for identifying differential gene pair co-expression patterns in prostate cancer progression

Mo, W. J., Fu, X., Han, X., Yang, G. Y., Zhang, J. G., Guo, F., Huang, Y., Mao, Y. M., Li, Y., & Xie, Y. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-340 · Cited by 12 · see citing works

Neurotrophin Receptor Activation and Expression in Human Postmortem Brain: Effect of Suicide

Dwivedi, Y., Rizavi, H., Zhang, H., Mondal, A., Roberts, R. C., Conley, R. R., & Pandey, G. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.08.035 · Cited by 3 · see citing works

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

Brites, D., & Fernandes, A. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00476 · Cited by 599 · see citing works

Treatment resistant depression: A multi-scale, systems biology approach

Akil, H., Gordon, J. A., Hen, R., Javitch, J. A., Mayberg, H. S., McEwen, B. S., Meaney, M. J., & Nestler, E. J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.08.019 · Cited by 443 · see citing works

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

Luciano, M., Hagenaars, S. P., Davies, G., Hill, W. D., Clarke, T.-K., Shirali, M., Harris, S. E., Marioni, R. E., Liewald, D. C., Fawns-Ritchie, C., et al. (2018) · Nature Genetics · doi:10.1038/s41588-017-0013-8 · Cited by 391 · see citing works

Epigenetic mechanisms of major depression: Targeting neuronal plasticity

Uchida, S., Yamagata, H., Seki, T., & Watanabe, Y. (2018) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12621 · Cited by 181 · see citing works

Neuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression

Xian, X., Cai, L.-L., Li, Y., Wang, R.-C., Xu, Y.-H., Chen, Y.-J., Xie, Y.-H., Zhu, X.-L., & Li, Y.-F. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01332-w · Cited by 169 · see citing works

MicroRNAs and exosomes in depression: Potential diagnostic biomarkers

Tavakolizadeh, J., Roshanaei, K., Salmaninejad, A., Yari, R., Nahand, J. S., Khoshdel‐Sarkarizi, H., Mousavi, S. M., Salarinia, R., Rahmati, M., Mousavi, S. F., et al. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26599 · Cited by 160 · see citing works

Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice

Higuchi, F., Uchida, S., Yamagata, H., Abe-Higuchi, N., Hobara, T., Hara, K., Kobayashi, A., Shintaku, T., Itoh, Y., Suzuki, T., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0319-16.2016 · Cited by 158 · see citing works

Depressive disorders: treatment failures and poor prognosis over the last 50 years

Blackburn, T. P. (2019) · Pharmacology Research &amp; Perspectives · doi:10.1002/prp2.472 · Cited by 136 · see citing works

Omics-Based Biomarkers: Application of Metabolomics in Neuropsychiatric Disorders

Sethi, S., & Brietzke, E. M. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv096 · Cited by 122 · see citing works

Borderline personality disorder and childhood maltreatment: A genome-wide methylation analysis

Prados, J., Stenz, L., Courtet, P., Prada, P., Nicastro, R., Adouan, W., Guillaume, S., Olié, E., Aubry, J. ‐., Dayer, A., et al. (2015) · Genes, Brain and Behavior · doi:10.1111/gbb.12197 · Cited by 112 · see citing works

Biomarkers for major depressive disorder

Hacımusalar, Y., & Eşel, E. (2017) · Nöro Psikiyatri Arşivi · doi:10.5152/npa.2017.19482 · Cited by 120 · see citing works

Neuron-derived extracellular vesicles enriched from plasma show altered size and miRNA cargo as a function of antidepressant drug response

Saeedi, S., Nagy, C., Ibrahim, P., Théroux, J., Wakid, M., Fiori, L. M., Yang, J., Rotzinger, S., Foster, J. A., Mechawar, N., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01255-2 · Cited by 108 · see citing works

Novel drug developmental strategies for treatment‐resistant depression

Borbély, É., Simon, M., Fuchs, E., Wiborg, O., Czéh, B., & Helyes, Z. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15753 · Cited by 111 · see citing works

Circulating microRNA-144-5p is associated with depressive disorders

Wang, X., Sundquist, K., Hedelius, A., Palmér, K., Memon, A. A., & Sundquist, J. (2015) · Clinical Epigenetics · doi:10.1186/s13148-015-0099-8 · Cited by 102 · see citing works

Exploiting Circulating MicroRNAs as Biomarkers in Psychiatric Disorders

Roy, B., Yoshino, Y., McKibben, L. A., Prall, K., Schell, G., & Dwivedi, Y. (2020) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-020-00464-9 · Cited by 95 · see citing works

MeCP2 controls hippocampal brain-derived neurotrophic factor expression via homeostatic interactions with microRNA-132 in rats with depression

Su, M., HONG, J., ZHAO, Y., Liu, S., & XUE, X. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4104 · Cited by 89 · see citing works

Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes

Luarte, A., Cisternas, P., Caviedes, A., Bátiz, L. F., Lafourcade, C., Wyneken, Ú., & Henzi, R. (2017) · Stem Cells International · doi:10.1155/2017/1719050 · Cited by 87 · see citing works

Altered miRNA expression network in locus coeruleus of depressed suicide subjects

Roy, B., Wang, Q., Palkovits, M., Faludi, G., & Dwivedi, Y. (2017) · Scientific Reports · doi:10.1038/s41598-017-04300-9 · Cited by 86 · see citing works

Circulating microRNAs as biomarkers for depression: Many candidates, few finalists

Yuan, H., Mischoulon, D., Fava, M., & Otto, M. W. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.06.058 · Cited by 86 · see citing works

Non-Coding RNAs in Psychiatric Disorders and Suicidal Behavior

Yoshino, Y., & Dwivedi, Y. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.543893 · Cited by 82 · see citing works

The Missing Link: How Exosomes and miRNAs can Help in Bridging Psychiatry and Molecular Biology in the Context of Depression, Bipolar Disorder and Schizophrenia.

Gruzdev, S. K., Yakovlev, A. A., Druzhkova, T. A., Guekht, A. B., & Gulyaeva, N. V. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-019-00684-6 · Cited by 75 · see citing works

The Role of MicroRNAs in Environmental Risk Factors, Noise-Induced Hearing Loss, and Mental Stress

Miguel, V., Cui, J. Y., Daimiel, L., Espinosa‐Díez, C., Fernandez-Hernando, C. F., Kavanagh, T. J., & Lamas, S. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7175 · Cited by 77 · see citing works

Circulating Plasma Micro RNAs in Patients with Major Depressive Disorder Treated with Antidepressants: A Pilot Study

ENĂTESCU, V. R., Papavă, I., Enătescu, I., Antonescu, M., Anghel, A., Șeclăman, E. P., Sîrbu, I. O., & Marian, C. (2016) · Psychiatry Investigation · doi:10.4306/pi.2016.13.5.549 · Cited by 73 · see citing works

MicroRNA-451a, microRNA-34a-5p, and microRNA-221-3p as predictors of response to antidepressant treatment

Kuang, W.-H., Dong, Z.-Q., Tian, L.-T., & Li, J. (2018) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20187212 · Cited by 70 · see citing works

Understanding epigenetic architecture of suicide neurobiology: A critical perspective

Roy, B., & Dwivedi, Y. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.10.031 · Cited by 69 · see citing works

Microglia and HPA axis in depression: An overview of participation and relationship

Pereira, G. C., Piton, E., dos Santos, B. M., Ramanzini, L. G., Camargo, L. F. M., da Silva, R. M., & Bochi, G. V. (2021) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2021.1939154 · Cited by 69 · see citing works

Crosstalk Among NLRP3 Inflammasome, ETBR Signaling, and miRNAs in Stress-Induced Depression-Like Behavior: a Modulatory Role for SGLT2 Inhibitors

Muhammad, R. N., Ahmed, L. A., Abdelsalam, R. M., Ahmed, K. A., & Attia, A. S. (2021) · Neurotherapeutics · doi:10.1007/s13311-021-01140-4 · Cited by 68 · see citing works

MiR-134 modulates chronic stress-induced structural plasticity and depression-like behaviors via downregulation of Limk1/cofilin signaling in rats

Fan, C., Zhu, X., Song, Q., Wang, P., Liu, Z., & Yu, S. Y. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.01.009 · Cited by 63 · see citing works

Function of exosomes in neurological disorders and brain tumors

Xiao, L., Hareendran, S., & Loh, Y. P. (2021) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2021.04 · Cited by 62 · see citing works

Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats

Wan, Y.-Q., Feng, J.-G., Li, M., Wang, M.-Z., Liu, L., Liu, X., Duan, X.-X., Zhang, C.-X., & Wang, X.-B. (2018) · Experimental &amp; Molecular Medicine · doi:10.1038/s12276-018-0164-4 · Cited by 60 · see citing works

miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation

Lou, D., Wang, J., & Wang, X. (2019) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2019.101470 · Cited by 58 · see citing works

Differential serum exosome microRNA profile in a stress-induced depression rat model

Fang, K., Xu, J., Chen, X.-X., Gao, X., Huang, L.-L., Du, A.-Q., Jiang, C., & Ge, J. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.05.017 · Cited by 61 · see citing works

Altered expression of neuroplasticity-related genes in the brain of depressed suicides

Fuchsová, B., Juliá, A. A., Rizavi, H. S., Frasch, A. C. C., & Pandey, G. N. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.04.057 · Cited by 59 · see citing works

Identification of a MicroRNA Signature for the Diagnosis of Fibromyalgia

Cerdá‐Olmedo, G., Mena-Durán, A. V., Monsalve, V., & Oltra, E. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121903 · Cited by 58 · see citing works

Abnormal expression profile of plasma-derived exosomal microRNAs in patients with treatment-resistant depression

Li, L., Naveed, M., Du, Z., Ding, H., Gu, K., Wei, L., Zhou, Y., Meng, F. J., Wang, C., Han, F., et al. (2021) · Human Genomics · doi:10.1186/s40246-021-00354-z · Cited by 57 · see citing works

Two Chronic Stress Models Based on Movement Restriction in Rats Respond Selectively to Antidepressant Drugs: Aldolase C As a Potential Biomarker

Ampuero, E., Luarte, A., Santibáñez, M., Varas‐Godoy, M., Toledo, J. A., Díaz‐Véliz, G., Cavada, G., Rubio, F. J., & Wyneken, Ú. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv038 · Cited by 57 · see citing works

Anxiety-Related Behaviours Associated with microRNA-206-3p and BDNF Expression in Pregnant Female Mice Following Psychological Social Stress

Miao, Z., Mao, F., Liang, J., Szyf, M., Wang, Y., & Sun, Z. S. (2017) · Molecular Neurobiology · doi:10.1007/s12035-016-0378-1 · Cited by 57 · see citing works

MicroRNAs as critical biomarkers of major depressive disorder: a comprehensive perspective

Ortega, M. A., Alvarez-Mon, M. A., García-Montero, C., Fraile-Martinez, O., Lahera, G., Monserrat, J., Muñoz-Merida, L., Mora, F., Rodríguez-Jiménez, R., Fernandez-Rojo, S., et al. (2021) · Biomedicines · doi:10.3390/biomedicines9111659 · Cited by 57 · see citing works

Genome-wide microarray analysis of gene expression profiling in major depression and antidepressant therapy

Lin, E., & Tsai, S. (2015) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.02.008 · Cited by 55 · see citing works

Psychotherapy and Genetic Neuroscience: An Emerging Dialog

Jiménez, J. P., Botto, A., Herrera, L., Leighton, C., Rossi, J. L., Quevedo, Y., Silva, J. R., Martínez, F. I., Assar, R., Salazar, L. A., et al. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00257 · Cited by 58 · see citing works

Epigenetic alterations associated with childhood trauma and adult mental health outcomes: A systematic review

Nöthling, J., Malan-Müller, S., Abrahams, N., Hemmings, S. M. J., & Seedat, S. (2020) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2019.1583369 · Cited by 74 · see citing works

Deficiency in Androgen Receptor Aggravates the Depressive-Like Behaviors in Chronic Mild Stress Model of Depression

Hung, Y.-Y., Huang, Y., Chang, C., & Kang, H. (2019) · Cells · doi:10.3390/cells8091021 · Cited by 51 · see citing works

miR-30 Family miRNAs Mediate the Effect of Chronic Social Defeat Stress on Hippocampal Neurogenesis in Mouse Depression Model

Khandelwal, N., Dey, S. K., Chakravarty, S., & Kumar, A. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00188 · Cited by 49 · see citing works

Seeking an Objective Diagnosis of Depression

Bilello, J. A. (2016) · Biomarkers in Medicine · doi:10.2217/bmm-2016-0076 · Cited by 49 · see citing works

Anabolic Androgenic Steroids: Searching New Molecular Biomarkers

Sessa, F., Salerno, M., Mizio, G. D., Bertozzi, G., Messina, G., Tomaiuolo, B., Pisanelli, D., Maglietta, F., Ricci, P., & Pomara, C. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01321 · Cited by 49 · see citing works

Heterogeneity and Individuality: microRNAs in Mental Disorders

Hommers, L. G., Domschke, K., & Deckert, J. (2014) · Journal of Neural Transmission · doi:10.1007/s00702-014-1338-4 · Cited by 45 · see citing works

MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism

Miguel-Hidalgo, J. J., Hall, K. O., Bonner, H., Roller, A., Syed, M., Park, C. J., Ball, J. P., Rothenberg, M. E., Stockmeier, C. A., & Romero, D. G. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.08.009 · Cited by 45 · see citing works

MicroRNAs expressed in depression and their associated pathways: A systematic review and a bioinformatics analysis

Ferrúa, C. P., Giorgi, R., Camerini, L., do Amaral, C. C., Ghisleni, G., Pinheiro, R. T., & Nedel, F. (2019) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2019.101650 · Cited by 44 · see citing works

Epigenetic mechanisms of stress and depression

Chmielewska, N., Szyndler, J., Maciejak, P., & Płaźnik, A. (2019) · Psychiatria Polska · doi:10.12740/pp/94375 · Cited by 46 · see citing works

Precision pharmacotherapy: psychiatry&amp;rsquo;s future direction in preventing, diagnosing, and treating mental disorders

Menke, A. (2018) · Pharmacogenomics and Personalized Medicine · doi:10.2147/pgpm.s146110 · Cited by 41 · see citing works

Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's Disease, Depression, Schizophrenia and Ionizing Radiation Exposure

Segaran, R. C., Chan, L. Y., Wang, H., Sethi, G., & Tang, F. R. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666200121122910 · Cited by 42 · see citing works

Peripheral blood micro RNA and VEGFA mRNA changes following electroconvulsive therapy: implications for psychotic depression

Kolshus, E., Ryan, K. M., Blackshields, G., Smyth, P. C., Sheils, O. M., & McLoughlin, D. M. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12821 · Cited by 43 · see citing works

MicroRNAs, Multiple Sclerosis, and Depression

Wang, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157802 · Cited by 45 · see citing works

Gut microbiome-gut brain axis-depression: interconnection

Patel, R. A., Panche, A. N., & Harke, S. N. (2024) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2024.2436854 · Cited by 43 · see citing works

A Systematic Review of Circulatory microRNAs in Major Depressive Disorder: Potential Biomarkers for Disease Prognosis

Rasheed, M., Asghar, R., Firdoos, S., Ahmad, N., Nazir, A., Ullah, K. M., Li, N., Zhuang, F., Chen, Z., & Deng, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031294 · Cited by 41 · see citing works

Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress – An animal model of depression

Żurawek, D., Kuśmider, M., Faron‐Górecka, A., Gruca, P., Pabian, P., Kolasa, M., Solich, J., Szafran‐Pilch, K., Papp, M., & Dziedzicka‐Wasylewska, M. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.11.013 · Cited by 38 · see citing works

MicroRNA-26a-2 maintains stress resiliency and antidepressant efficacy by targeting the serotonergic autoreceptor HTR1A

Xie, L., Chen, J., Yong-min, D., Gui, X., Wu, L., Tian, S., & Wu, W. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.02.078 · Cited by 38 · see citing works

Therapeutic role of long non-coding RNA TCONS_00019174 in depressive disorders is dependent on Wnt/β-catenin signaling pathway

Ni, X., Liao, Y., Li, L., Zhang, X., & Wu, Z. (2018) · Journal of Integrative Neuroscience · doi:10.31083/jin-170052 · Cited by 37 · see citing works

Circulating Long Noncoding RNAs as Novel Biomarkers of Human Diseases

Jiang, X., Lei, R., & Ning, Q. (2016) · Biomarkers in Medicine · doi:10.2217/bmm-2016-0039 · Cited by 34 · see citing works

MicroRNAs in Psychological Stress Reactions and Their Use as Stress-Associated Biomarkers, Especially in Human Saliva

Wiegand, C., Savelsbergh, A., & Heusser, P. (2017) · Biomedicine Hub · doi:10.1159/000481126 · Cited by 34 · see citing works

Identification of key genes, pathways and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis

Ma, K., Zhang, H., Wei, G., Dong, Z., Zhao, H., Han, X., Song, X., Zhang, H., Zong, X., Baloch, Z., et al. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s200264 · Cited by 32 · see citing works

Potential of Circulating miRNAs as Molecular Markers in Mood Disorders and Associated Suicidal Behavior

Roy, B., Ochi, S., & Dwivedi, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054664 · Cited by 33 · see citing works

Expression and Biological Functions of miRNAs in Chronic Pain: A Review on Human Studies

Sabina, S., Panìco, A., Mincarone, P., Leo, C. G., Garbarino, S., Grassi, T., Bagordo, F., Donno, A. D., Scoditti, E., & Tumolo, M. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116016 · Cited by 34 · see citing works

miR-138 Increases Depressive-Like Behaviors by Targeting SIRT1 in Hippocampus

Li, C., Wang, F., Pei, M., Yan, L., Liu, S., Wang, X., Jin, Z., & Gu, Z. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s237558 · Cited by 31 · see citing works

Differential exosomal microRNA profile in the serum of a patient with depression

Zhang, Y., Zhao, Y., Tian, C., Wang, J., Li, W., & Zhong, C. (2017) · The European Journal of Psychiatry · doi:10.1016/j.ejpsy.2017.10.002 · Cited by 29 · see citing works

Genetic variants in the promoters of let-7 family are associated with an increased risk of major depressive disorder

Liang, Y., Zhao, G., Sun, R., Mao, Y., Li, G., Chen, X., Gao, L., & Hu, Z. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.04.035 · Cited by 28 · see citing works

Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy

McGrory, C. L., Ryan, K. M., Kolshus, E., Finnegan, M., & McLoughlin, D. M. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.06.007 · Cited by 28 · see citing works

Early life and adult stress promote sex dependent changes in hypothalamic miRNAs and environmental enrichment prevents stress-induced miRNA and gene expression changes in rats

McKibben, L. A., & Dwivedi, Y. (2021) · BMC Genomics · doi:10.1186/s12864-021-08003-4 · Cited by 27 · see citing works

Grape-Derived Polyphenols Ameliorate Stress-Induced Depression by Regulating Synaptic Plasticity

Caracci, F., Harary, J. M., Simkovic, S. J., & Pasinetti, G. M. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b01970 · Cited by 28 · see citing works

Physical exercise prevents mice from L-Kynurenine-induced depression-like behavior.

Su, C., Chuang, H., & Hong, C. (2019) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2019.101894 · Cited by 26 · see citing works

Therapeutic role of long non-coding RNA TCONS_00019174 in depressive disorders is dependent on Wnt/β-catenin signaling pathway

Ni, X., Liao, Y., Li, L., Zhang, X., & Wu, Z. (2018) · Journal of Integrative Neuroscience · doi:10.3233/jin-170052 · Cited by 26 · see citing works

M6A RNA Methylation-Based Epitranscriptomic Modifications in Plasticity-Related Genes via miR-124-C/EBPα-FTO-Transcriptional Axis in the Hippocampus of Learned Helplessness Rats

Roy, B., Ochi, S., & Dwivedi, Y. (2022) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyac068 · Cited by 25 · see citing works

MiR-186-5p Dysregulation Leads to Depression-like Behavior by De-repressing SERPINF1 in Hippocampus

Jiang, M., Gu, Y., Cai, J.-F., Wang, A., He, Y., & Feng, Y. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.10.005 · Cited by 26 · see citing works

Social stress in adolescents induces depression and brain-region-specific modulation of the transcription factor MAX

Resende, L. S., Amaral, C. E., Soares, R. B., Alves, A. S., Alves-dos-Santos, L., Britto, L. R. G., & Chiavegatto, S. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.202 · Cited by 26 · see citing works

Regulatory Role of MicroRNAs in Brain Development and Function

Yapijakis, C. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-32633-3_32 · Cited by 26 · see citing works

The Association between Depression and Gastroesophageal Reflux based on Phylogenetic Analysis of miRNA Biomarkers

Chen, Y., & Wang, H. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666200425214906 · Cited by 25 · see citing works

Sex-Dependent Changes in miRNA Expression in the Bed Nucleus of the Stria Terminalis Following Stress

Mavrikaki, M., Pantano, L., Potter, D. N., Rogers-Grazado, M., Anastasiadou, E., Slack, F. J., Amr, S. S., Ressler, K. J., Daskalakis, N. P., & Chartoff, E. H. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00236 · Cited by 24 · see citing works

Baiap3 regulates depressive behaviors in mice via attenuating dense core vesicle trafficking in subsets of prefrontal cortex neurons

Kim, H., Kim, J., Lee, H., Shin, E., Kang, H., Jeon, J., & Youn, B. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100423 · Cited by 24 · see citing works

Brain Regional and Temporal Changes in BDNF mRNA and microRNA-206 Expression in Mice Exposed to Repeated Cycles of Chronic Intermittent Ethanol and Forced Swim Stress

Solomon, M. G., Griffin, W. C., Lopez, M. F., & Becker, H. C. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.02.012 · Cited by 24 · see citing works

Drugs used to treat bipolar disorder act via microRNAs to regulate expression of genes involved in neurite outgrowth

Kidnapillai, S., Wade, B., Bortolasci, C. C., Panizzutti, B., Spolding, B., Connor, T., Crowley, T. M., Jamain, S., Gray, L. J., Leboyer, M., et al. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881119895534 · Cited by 23 · see citing works

Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus

Maulik, U., Sen, S., Mallik, S., & Bandyopadhyay, S. (2018) · BMC Genetics · doi:10.1186/s12863-017-0574-7 · Cited by 23 · see citing works

MiRNA‐199a‐5p targets WNT2 to regulate depression through the CREB/BDNF signaling in hippocampal neuron

Liu, Z., Yang, J., Fang, Q., Shao, H., Yang, D., Sun, J., & Gao, L. (2021) · Brain and Behavior · doi:10.1002/brb3.2107 · Cited by 22 · see citing works

Expression of miRNA-124a in CD4 Cells Reflects Response to a Multidisciplinary Treatment Program in Patients With Chronic Low Back Pain

Luchting, B., Heyn, J., Hinske, L. C., & Azad, S. C. (2016) · Spine · doi:10.1097/brs.0000000000001763 · Cited by 23 · see citing works

Prefrontal cortex miR‐874‐3p prevents lipopolysaccharide‐induced depression‐like behavior through inhibition of indoleamine 2,3‐dioxygenase 1 expression in mice

Suento, W. J., Kunisawa, K., Wulaer, B., Kosuge, A., Iida, T., Fujigaki, S., Fujigaki, H., Yamamoto, Y., Tanra, A. J., Saito, K., et al. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15222 · Cited by 22 · see citing works

Periodontal Pathogens and Neuropsychiatric Health

Wadhawan, A., Reynolds, M. A., Makkar, H., Scott, A. J., Potocki, E., Hoisington, A. J., Brenner, L. A., Dagdag, A., Lowry, C. A., Dwivedi, Y., et al. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666200110161105 · Cited by 22 · see citing works

Chronic stress induces behavioural changes through increased kynurenic acid by downregulation of kynurenine‐3‐monooxygenase with microglial decline

Hasegawa, M., Kunisawa, K., Wulaer, B., Kubota, H., Kurahashi, H., Sakata, T., Ando, H., Fujigaki, S., Fujigaki, H., Yamamoto, Y., et al. (2024) · British Journal of Pharmacology · doi:10.1111/bph.17407 · Cited by 20 · see citing works

Uncovering the Roles of MicroRNAs in Major Depressive Disorder: From Candidate Diagnostic Biomarkers to Treatment Response Indicators

Homorogan, C., Nițușcă, D., Șeclăman, E. P., ENĂTESCU, V. R., & Marian, C. (2021) · Life · doi:10.3390/life11101073 · Cited by 20 · see citing works

Understanding the Neuroepigenetic Constituents of Suicide Brain

Roy, B., & Dwivedi, Y. (2018) · Progress in Molecular Biology and Translational Science · doi:10.1016/bs.pmbts.2018.01.007 · Cited by 17 · see citing works

The role of circulating blood microRNA-374 and microRNA-10 levels in the pathogenesis and therapeutic mechanisms of major depressive disorder

Liu, W., Zhang, F., Zheng, Y., Shen, H., Zhang, T., Guo, Q., Xu, H. J., Chen, H., Liu, C., Yu, S., et al. (2021) · Neuroscience Letters · doi:10.1016/j.neulet.2021.136184 · Cited by 18 · see citing works

Therapeutic Implications of microRNAs in Depressive Disorders: A Review

Hassan, M., Amir, A., Shahzadi, S., & Kloczkowski, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113530 · Cited by 19 · see citing works

A Genome-Wide Association Study and Complex Network Identify Four Core Hub Genes in Bipolar Disorder

Xie, Z., Yang, X., Deng, X., Ma, M.-Y., & Shu, K. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18122763 · Cited by 15 · see citing works

Revision to psychopharmacology mRNA and microRNA profiles are associated with stress susceptibility and resilience induced by psychological stress in the prefrontal cortex

Yang, J., Sun, J., Lu, Y., An, T., Lu, W., & Wang, J. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05593-x · Cited by 16 · see citing works

MicroRNA-382-5p Targets Nuclear Receptor Subfamily 3 Group C Member 1 to Regulate Depressive-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Rats

Li, S., Ma, H., Yuan, X., Zhou, X., Wan, Y., & Chen, S. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s243920 · Cited by 17 · see citing works

miR-218: A Stress-Responsive Epigenetic Modifier

Schell, G., Roy, B., Prall, K., & Dwivedi, Y. (2022) · Non-Coding RNA · doi:10.3390/ncrna8040055 · Cited by 17 · see citing works

A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin

Mendez‐David, I., David, D. J., Deloménie, C., Tritschler, L., Beaulieu, J., Colle, R., Corruble, E., Gardier, A. M., & Hen, R. (2023) · Hippocampus · doi:10.1002/hipo.23568 · Cited by 15 · see citing works

Diagnostic value of MicroRNAs for depression: A systematic review and meta-analysis

Li, W., Li, X., Li, Y., Chen, Y., Zhu, L., & Guo, R. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.11.028 · Cited by 14 · see citing works

miRNAs in treatment-resistant depression: a systematic review

Cai, L., Xu, J., Liu, J., Luo, H., Yang, R., Gui, X., & Wei, L. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09554-x · Cited by 14 · see citing works

Effect of citalopram and sertraline on the expression of miRNA- 124, 132, and 16 and their protein targets in patients with depression.

Ahmadimanesh, M., Etemad, L., Rad, D. M., Ghahremani, M. H., Mohammadpour, A. H., Esfehani, R. J., Jowsey, P. A., Behdani, F., Moallem, S. A., & Abbaszadegan, M. R. (2023) · PubMed Central · doi:10.22038/ijbms.2023.66496.14595 · Cited by 13 · see citing works

mRNA and miRNA profiles in the nucleus accumbens are associated with psychological stress-induced susceptible and resilient mice

Lu, Y., Yang, J., Sun, J., Lu, W., & Wang, J. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173062 · Cited by 13 · see citing works

Elevated miR-34a expression and altered transcriptional profile are associated with adverse electromechanical remodeling in the heart of male rats exposed to social stress

Andolina, D., Savi, M., Ielpo, D., Barbetti, M., Bocchi, L., Stilli, D., Ventura, R., Iacono, L. L., Sgoifo, A., & Carnevali, L. (2021) · Stress · doi:10.1080/10253890.2021.1942830 · Cited by 13 · see citing works

Emerging role of microRNAs in major depressive disorder and its implication on diagnosis and therapeutic response

Zhou, L., Zhu, Y., Chen, W., & Tang, Y. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.02.063 · Cited by 49 · see citing works

MicroRNAs as Diagnostic and Therapeutic Biomarkers in Major Depressive Disorder

Maroufi, M., Asgharzadeh, M. R., Dahmardeh, N., Valipour, A. M., & Kardan, N. (2026) · IGI Global eBooks · doi:10.4018/979-8-2600-4270-0.ch003

microRNAs as Biomarker in Depression Pathogenesis.

Dwivedi, Y. (2013) · PubMed · Cited by 19 · see citing works

Uncovering the Roles of MicroRNAs in Major Depressive Disorder: From Candidate Diagnostic Biomarkers to Treatment Response Indicators

Homorogan, C., Nițușcă, D., Șeclăman, E. P., ENĂTESCU, V. R., & Marian, C. (2021) · Life · doi:10.3390/life11101073 · Cited by 20 · see citing works

Pathogenetic and therapeutic applications of microRNAs in major depressive disorder

Dwivedi, Y. (2015) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.02.003 · Cited by 70 · see citing works