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Cited by 625

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Nitric Oxide Measured by a Porphyrinic Micro Sensor in Rat Brain after Transient Middle Cerebral Artery Occlusion

Malinski, T., Bailey, F., Zhang, Z. G., Chopp, M.·1993·Journal of Cerebral Blood Flow & Metabolism

Abstract

We measured, in vivo, the local concentration of nitric oxide (NO) in cerebral tissue, during and after transient middle cerebral artery occlusion in the rat (n = 8). Baseline concentration of NO was <10−8 M; upon initiation of ischemia, NO concentration increased to ∼10−6 M and then declined. Reperfusion likewise stimulated an increase in NO concentration to above baseline level. Administration of N-nitro-l-arginine methyl ester (n = 4), an inhibitor of nitric oxide synthase, before onset of ischemia, maintained NO at basal levels. Our data indicate that large increases in NO occur at onset of ischemia, which may affect tissue response to an ischemic insult.

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Crossref · 10.1038/jcbfm.1993.48

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Metadata

Authors
Malinski, T., Bailey, F., Zhang, Z. G., & Chopp, M.
Venue
Journal of Cerebral Blood Flow & Metabolism
Published
1993-05
Volume
13
Issue
3
Pages
355-358
ISSN
  • 0271-678X (ISSN-L)
  • 1559-7016
OpenAlex
W2085935168
Cited by
625
References
2
FWCI
29.33
Type
journal article
Language
en
Open access
closed

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.