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The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions

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The Vitamin D Sterol–Vitamin D Receptor Ensemble Model Offers Unique Insights into Both Genomic and Rapid-Response Signaling

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A pathway for the metabolism of vitamin D ₃ : Unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1)

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1 , 25-dihydroxyvitamin D3 suppresses interleukin-8-mediated prostate cancer cell angiogenesis

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Vitamin D: an ancient hormone

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Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism

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Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, l-tyrosine and l-dopa

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Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1α,25(OH) 2 -vitamin D 3 signaling

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Dietary habits and stomach cancer in Shanghai, China

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1,25-DIHYDROXYVITAMIN-D RECEPTOR IN BREAST CANCER CELLS

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Melanocytes as "Sensory" and Regulatory Cells in the Epidermis

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Association between serum 25(OH)D and death from prostate cancer

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The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism

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25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis

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Molecular diagnostics in melanoma

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Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity

Slominski, A. T., Janjetovic, Z., Fuller, B. E., Zmijewski, M. A., Tuckey, R. C., Nguyen, M. N., Sweatman, T., Li, W., Zjawiony, J., Miller, D., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009907 · Cited by 149 · see citing works

Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case–control comparisons and a meta-analysis of published VDR data

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Endogenously produced nonclassical vitamin D hydroxy-metabolites act as “biased” agonists on VDR and inverse agonists on RORα and RORγ

Slominski, A. T., Kim, T.-K., Hobrath, J. V., Oak, A. S. W., Tang, E. K. Y., Tieu, E. W., Li, W., Tuckey, R. C., & Jetten, A. M. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2016.09.024 · Cited by 143 · see citing works

Growth inhibition of both MCF-7 and Hs578T human breast cancer cell lines by vitamin D analogues is associated with increased expression of insulin-like growth factor binding protein-3

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Dual functions of autophagy in the response of breast tumor cells to radiation

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Cytotoxic Autophagy in Cancer Therapy

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20-Hydroxycholecalciferol, Product of Vitamin D3 Hydroxylation by P450scc, Decreases NF-κB Activity by Increasing IκBα Levels in Human Keratinocytes

Janjetovic, Z., Zmijewski, M. A., Tuckey, R. C., DeLeon, D. A., Nguyen, M. N., Pfeffer, L. M., & Slominski, A. T. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005988 · Cited by 130 · see citing works

Melanoma Resistance: A Bright Future for Academicians and a Challenge for Patient Advocates

Slominski, A. T., & Carlson, J. A. (2014) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2014.02.009 · Cited by 128 · see citing works

CRH functions as a growth factor/cytokine in the skin

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Neuroendocrine activity of the melanocyte

Slominski, A. T. (2009) · Experimental Dermatology · doi:10.1111/j.1600-0625.2009.00892.x · Cited by 125 · see citing works

Targeted therapy for melanoma: rational combinatorial approaches

Kwong, L. N., & Davies, M. A. (2013) · Oncogene · doi:10.1038/onc.2013.34 · Cited by 123 · see citing works

Expression of vitamin D receptor decreases during progression of pigmented skin lesions

Brożyna, A. A., Jozwicki, W., Janjetovic, Z., & Slominski, A. T. (2011) · Human Pathology · doi:10.1016/j.humpath.2010.09.014 · Cited by 120 · see citing works

Melanocytes are deficient in repair of oxidative DNA damage and UV-induced photoproducts

Wang, H.-T., Choi, B., & Tang, M.-S. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005244107 · Cited by 119 · see citing works

Increased Levels of 25 Hydroxyvitamin D and 1,25-Dihydroxyvitamin D After Rosuvastatin Treatment: A Novel Pleiotropic Effect of Statins?

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Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc

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20-Hydroxyvitamin D3, a product of vitamin D3 hydroxylation by cytochrome P450scc, stimulates keratinocyte differentiation

Zbytek, B., Janjetovic, Z., Tuckey, R. C., Zmijewski, M. A., Sweatman, T. W., Jones, E., Nguyen, M. N., & Slominski, A. T. (2008) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.62 · Cited by 118 · see citing works

Vitamin D and melanoma and non-melanoma skin cancer risk and prognosis: A comprehensive review and meta-analysis

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20-Hydroxyvitamin D₂ is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells

Slominski, A. T., Kim, T.-K., Janjetovic, Z., Tuckey, R. C., Bieniek, R., Yue, J., Li, W., Chen, J., Nguyen, M. N., Tang, E. K. Y., et al. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00203.2010 · Cited by 113 · see citing works

1α,25(OH)2-Vitamin D and a Nongenomic Vitamin D Analogue Inhibit Ultraviolet Radiation–Induced Skin Carcinogenesis

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A Switch Between Cytoprotective and Cytotoxic Autophagy in the Radiosensitization of Breast Tumor Cells by Chloroquine and Vitamin D

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The Contributions of Solar Ultraviolet Radiation Exposure and Other Determinants to Serum 25-Hydroxyvitamin D Concentrations in Australian Adults: The AusD Study

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Inhibition of melanogenesis as an adjuvant strategy in the treatment of melanotic melanomas: selective review and hypothesis.

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Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling

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1alpha,25-(OH)(2)-D(3) and its synthetic analogue decrease tumor load in the Apc(min) Mouse.

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The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

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VDR activation of intracellular signaling pathways in skeletal muscle

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20,23‐dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF‐κB activity in human keratinocytes

Janjetovic, Z., Tuckey, R. C., Nguyen, M. N., Thorpe, E. M., & Slominski, A. T. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.21992 · Cited by 103 · see citing works

Conditional ablation of Ikkb inhibits melanoma tumor development in mice

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Vitamin D receptor, a tumor suppressor in skin

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In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes Caco-2 colon cells and the adrenal gland

Slominski, A. T., Kim, T.-K., Shehabi, H. Z., Tang, E. K. Y., Benson, H. A. E., Semak, I., Lin, Z., Yates, C. R., Wang, J., Li, W., et al. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.12.012 · Cited by 100 · see citing works

Cancer Incidence and Mortality and Vitamin D in Black and White Male Health Professionals

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Melatonin and vitamin D3 synergistically down‐regulate Akt and MDM2 leading to TGFβ‐1‐dependent growth inhibition of breast cancer cells

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Sunlight Vitamin D and Skin Cancer

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An alternative pathway of vitamin D₂ metabolism: Cytochrome P450scc (CYP11A1)‐mediated conversion to 20‐hydroxyvitamin D₂ and 17,20‐dihydroxyvitamin D₂

Slominski, A., Semak, I., Wortsman, J., Zjawiony, J., Li, W., Zbytek, B., & Tuckey, R. C. (2006) · The FEBS Journal · doi:10.1111/j.1742-4658.2006.05302.x · Cited by 98 · see citing works

Latest Advances in Chemotherapeutic, Targeted, and Immune Approaches in the Treatment of Metastatic Melanoma

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Regulation of insulin-like growth factor (IGF) II and IGF binding protein 3 autocrine loop in human PC-3 prostate cancer cells by vitamin D metabolite 1,25(OH)2D3 and its analog EB1089.

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Targeting autophagy as a potential therapeutic approach for melanoma therapy

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High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives

Janjetovic, Z., Brozyna, A. A., Tuckey, R. C., Kim, T.-K., Nguyen, M. N., Jozwicki, W., Pfeffer, S. R., Pfeffer, L. M., & Slominski, A. T. (2011) · British Journal of Cancer · doi:10.1038/bjc.2011.458 · Cited by 91 · see citing works

Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways

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Vitamin D Receptor and Growth Inhibition by 1,25-Dihydroxyvitamin D3in Human Malignant Melanoma Cell Lines

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Sequential metabolism of 7-dehydrocholesterol to steroidal 5, 7-dienes in adrenal glands and its biological implication in the skin

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1,25(OH)2Vitamin D3Induces Elevated Expression of the Cell Cycle-regulating Genes P21 and P27 in Squamous Carcinoma Cell Lines of the Head and Neck

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Production of 22-hydroxy metabolites of vitamin D3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cells

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The Role of the Vitamin D Receptor and ERp57 in Photoprotection by 1α,25-Dihydroxyvitamin D3

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Differential apoptotic response of human melanoma cells to 1α,25-dihydroxyvitamin D3 and its analogues

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Convergence of vitamin D and retinoic acid signalling at a common hormone response element

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Decreased VDR expression in cutaneous melanomas as marker of tumor progression: new data and analyses.

Brożyna, A. A., Jóźwicki, W., & Slominski, A. T. (2014) · PubMed · Cited by 87 · see citing works

CYP24A1 and CYP27B1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells

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High incidence of T-cell lymphomas in mice deficient in the retinoid-related orphan receptor RORgamma.

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L‐Tyrosine, L‐DOPA, and Tyrosinase as Positive Regulators of the Subcellular Apparatus of Melanogenesis in Bomirski Ab Amelanotic Melanoma Cells

Slominski, A. T., Moellmann, G. E., & Kuklinska, E. (1989) · Pigment Cell Research · doi:10.1111/j.1600-0749.1989.tb00170.x · Cited by 85 · see citing works

Melanoma—the run of success continues

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Malignant Transformation of DMBA/TPA-Induced Papillomas and Nevi in the Skin of Mice Selectively Lacking Retinoid-X-Receptor α in Epidermal Keratinocytes

Indra, A. K., Castañeda-Saucedo, E., Antal, M. C., Jiang, M., Messaddeq, N., Meng, X., Löhr, C. V., Gariglio, P., Kato, S., Wahli, W., et al. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700672 · Cited by 84 · see citing works

Novel vitamin D hydroxyderivatives inhibit melanoma growth and show differential effects on normal melanocytes.

Slominski, A. T., Janjetović, Z., Kim, T., Wright, A. C., Grese, L., Riney, S. J., Nguyen, M. N., & Tuckey, R. C. (2012) · PubMed · Cited by 84 · see citing works

1Alpha,25-dihydroxyvitamin D3 induces de novo E-cadherin expression in triple-negative breast cancer cells by CDH1-promoter demethylation.

Lopes, N., Carvalho, J., Durães, C., Sousa, B., Gomes, M., Costa, J. L., Oliveíra, C., Paredes, J., & Schmitt, F. C. (2012) · PubMed · Cited by 82 · see citing works

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes

Slominski, A. T., Kim, T.-K., Chen, J., Nguyen, M. N., Li, W., Yates, C. R., Sweatman, T., Janjetovic, Z., & Tuckey, R. C. (2012) · The International Journal of Biochemistry &amp; Cell Biology · doi:10.1016/j.biocel.2012.07.027 · Cited by 81 · see citing works

In vitro comparison of the vitamin D endocrine system in 1,25(OH)2D3-responsive and –Resistant melanoma cells

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Sunlight Vitamin D and Skin Cancer

Mason, R. S., & Reichrath, J. (2012) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152013804487272 · Cited by 81 · see citing works

Membrane Receptors for Vitamin D Metabolites

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Antitumoral Effects of Calcitriol in Basal Cell Carcinomas Involve Inhibition of Hedgehog Signaling and Induction of Vitamin D Receptor Signaling and Differentiation

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Genetic disorders of Vitamin D biosynthesis and degradation

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Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation

Slominski, A. T., Janjetovic, Z., Kim, T.-K., Wasilewski, P., Rosas, S., Hanna, S., Sayre, R. M., Dowdy, J. C., Li, W., & Tuckey, R. C. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.01.014 · Cited by 77 · see citing works

Novel vitamin D photoproducts and their precursors in the skin

Slominski, A., Kim, T.-K., Zmijewski, M. A., Janjetovic, Z., Li, W., Chen, J., Kusniatsova, E. I., Semak, I., Postlethwaite, A., Miller, D. D., et al. (2013) · Dermato-Endocrinology · doi:10.4161/derm.23938 · Cited by 76 · see citing works

Statins, Fibrates, and Melanoma Risk: a Systematic Review and Meta-analysis

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25‐Hydroxyvitamin D2/D3 levels and factors associated with systemic inflammation and melanoma survival in the Leeds Melanoma Cohort

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Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer

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20-hydroxyvitamin D₃ inhibits proliferation of cancer cells with high efficacy while being non-toxic.

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Association of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein

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Are L-tyrosine and L-dopa hormone-like bioregulators?

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Expression of the vitamin D–activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progression

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Joint Effects of Dietary Vitamin D and Sun Exposure on Breast Cancer Risk: Results from the French E3N Cohort

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RORα and RORγ expression inversely correlates with human melanoma progression

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Ultraviolet Damage, DNA Repair and Vitamin D in Nonmelanoma Skin Cancer and in Malignant Melanoma

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Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity

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Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non‐Hispanic whites in Texas: A case–control study

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Vitamin D receptor polymorphisms in patients with cutaneous melanoma

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1α,25-Dihydroxyvitamin D3 reduces several types of UV-induced DNA damage and contributes to photoprotection

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Emerging role of alternative splicing of CRF1 receptor in CRF signaling.

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Vitamin D Deficiency at Melanoma Diagnosis Is Associated with Higher Breslow Thickness

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Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view

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Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesis

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Calcitriol and Genistein Actions to Inhibit the Prostaglandin Pathway: Potential Combination Therapy to Treat Prostate Cancer ,3

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Classical and non‐classical metabolic transformation of vitamin D in dermal fibroblasts

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PRMT2 and RORγ Expression Are Associated With Breast Cancer Survival Outcomes

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Genetic Variants of the Vitamin D Receptor Gene Alter Risk of Cutaneous Melanoma

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Biologically active noncalcemic analogs of 1α,25-dihydroxyvitamin D with an abbreviated side chain containing no hydroxyl

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An Update on Vitamin D Metabolism

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Melanoma, Melanin, and Melanogenesis: The Yin and Yang Relationship

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The serum vitamin D metabolome: what we know and what is still to discover

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Photoprotective Properties of Vitamin D and Lumisterol Hydroxyderivatives

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Protective Effects of Novel Derivatives of Vitamin D3 and Lumisterol Against UVB-Induced Damage in Human Keratinocytes Involve Activation of Nrf2 and P53 Defense Mechanisms

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Differential and Overlapping Effects of 20,23(OH)2D3 and 1,25(OH)2D3 on Gene Expression in Human Epidermal Keratinocytes: Identification of AhR as an Alternative Receptor for 20,23(OH)2D3

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Vitamin D–VDR Signaling Inhibits Wnt/β-Catenin–Mediated Melanoma Progression and Promotes Antitumor Immunity

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Biological Effects of CYP11A1-Derived Vitamin D and Lumisterol Metabolites in the Skin

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On the role of classical and novel forms of vitamin D in melanoma progression and management

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Participation of keratinocyte‐ and fibroblast‐derived factors in melanocyte homeostasis, the response to UV, and pigmentary disorders

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Vitamin D Status and the Host Resistance to Infections: What It Is Currently (Not) Understood

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25-Hydroxyvitamin D and Total Cancer Incidence and Mortality: A Meta-Analysis of Prospective Cohort Studies

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Current Molecular Markers of Melanoma and Treatment Targets

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Malignant Melanoma: An Overview, New Perspectives, and Vitamin D Signaling

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Retinoic Acid Receptor-Related Orphan Receptors: Critical Roles in Tumorigenesis

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Association Between Parkinson’s Disease and Melanoma: Putting the Pieces Together

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Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention

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Relevance of Vitamin D in Melanoma Development, Progression and Therapy

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Immune Modulation by Vitamin D: Special Emphasis on Its Role in Prevention and Treatment of Cancer

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Gender Differences and Outcomes in Melanoma Patients

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Dysregulation of tyrosinase activity: a potential link between skin disorders and neurodegeneration

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The Role of Classical and Novel Forms of Vitamin D in the Pathogenesis and Progression of Nonmelanoma Skin Cancers

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Melanoma-Bearing Libechov Minipig (MeLiM): The Unique Swine Model of Hereditary Metastatic Melanoma

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Parkinson's disease and skin

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Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models

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MicroRNA-21-Enriched Exosomes as Epigenetic Regulators in Melanomagenesis and Melanoma Progression: The Impact of Western Lifestyle Factors

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Vitamin D in melanoma: Controversies and potential role in combination with immune check-point inhibitors

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Vitamina D y la piel. Una revisión para dermatólogos

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The Role of Calcium Signaling in Melanoma

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Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models

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Hydroxylumisterols, Photoproducts of Pre-Vitamin D3, Protect Human Keratinocytes against UVB-Induced Damage

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CYP11A1‑derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomas

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Vitamin D and the Skin: A Review for Dermatologists

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Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels

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The association between serum vitamin D level and risk and prognosis of melanoma: a systematic review and meta‐analysis

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Detection of 7-Dehydrocholesterol and Vitamin D3 Derivatives in Honey

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Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell line

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Vitamin�D derivatives potentiate the anticancer and anti-angiogenic activity of tyrosine kinase inhibitors in combination with cytostatic drugs in an A549 non-small cell lung cancer model

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Antiproliferative Activity of Non-Calcemic Vitamin D Analogs on Human Melanoma Lines in Relation to VDR and PDIA3 Receptors

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Role of vitamin D3 in selected malignant neoplasms

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Vitamin D and Other Differentiation‐promoting Agents as Neoadjuvants for Photodynamic Therapy of Cancer

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Metabolic Alterations and Therapeutic Opportunities in Rare Forms of Melanoma

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Vitamin D as therapeutic modulator in cerebrovascular diseases: a mechanistic perspectives

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QTL mapping for orange shell color and sex in the Pacific oyster (Crassostrea gigas)

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The Role of the Vitamin D Receptor in the Pathogenesis, Prognosis, and Treatment of Cutaneous Melanoma

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Knocking out the Vitamin D Receptor Enhances Malignancy and Decreases Responsiveness to Vitamin D3 Hydroxyderivatives in Human Melanoma Cells

Podgórska, E., Kim, T., Janjetović, Z., Urbańska, K., Tuckey, R. C., Bae, S., & Slominski, A. T. (2021) · Cancers · doi:10.3390/cancers13133111 · Cited by 26 · see citing works

Is Vitamin D Deficiency Related to Increased Cancer Risk in Patients with Type 2 Diabetes Mellitus?

Gabryanczyk, A., Klimczak, S., Szymczak-Pajor, I., & Śliwińska, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126444 · Cited by 25 · see citing works

On the relationship between VDR, RORα and RORγ receptors expression and HIF1‐α levels in human melanomas

Brożyna, A. A., Jóźwicki, W., Jetten, A. M., & Slominski, A. T. (2019) · Experimental Dermatology · doi:10.1111/exd.14002 · Cited by 25 · see citing works

Sex Disparity in Skin Carcinogenesis and Potential Influence of Sex Hormones

Collier, V. C., Musicante, M., Patel, T., & Liu, F. (2021) · Skin Health and Disease · doi:10.1002/ski2.27 · Cited by 24 · see citing works

Differential response of lung cancer cell lines to vitamin D derivatives depending on EGFR, KRAS, p53 mutation status and VDR polymorphism

Maj, E., Trynda, J., Maj, B., Gębura, K., Bogunia‐Kubik, K., Chodyński, M., Kutner, A., & Wietrzyk, J. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105431 · Cited by 23 · see citing works

Biology of Melanocytes and Primary Melanoma

Zaidi, M. R., Fisher, D. E., & Rizos, H. (2020) · Springer eBooks · doi:10.1007/978-3-030-05070-2_42 · Cited by 22 · see citing works

Photobiology of vitamin D

Holick, M. F., & Slominski, A. T. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91386-7.00006-4 · Cited by 22 · see citing works

Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low–LET Proton Beam Irradiation

Podgórska, E., Drzał, A., Matuszak, Z., Swakoń, J., Slominski, A. T., Elas, M., & Urbańska, K. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19082236 · Cited by 23 · see citing works

Understanding the Biological Activities of Vitamin D in Type 1 Neurofibromatosis: New Insights into Disease Pathogenesis and Therapeutic Design

Riccardi, C., Perrone, L., Napolitano, F., Sampaolo, S., & Melone, M. A. B. (2020) · Cancers · doi:10.3390/cancers12102965 · Cited by 21 · see citing works

Mitochondrial potassium channels: A novel calcitriol target

Olszewska, A., Sieradzan, A. K., Bednarczyk, P., Szewczyk, A. M., & Zmijewski, M. A. (2022) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-021-00299-0 · Cited by 21 · see citing works

Consideration of possible effects of vitamin D on established cancer, with reference to malignant melanoma

Hutchinson, P. E., & Pringle, J. H. (2022) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.13040 · Cited by 19 · see citing works

The burgeoning role of cytochrome P450-mediated vitamin D metabolites against colorectal cancer

Wang, P., Qin, X., Liu, M., & Wang, X. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.04.022 · Cited by 20 · see citing works

Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3

Brzeminski, P., Fabisiak, A., Slominski, R. M., Kim, T., Janjetović, Z., Podgórska, E., Song, Y., Saleem, M., Reddy, S. B., Qayyum, S., et al. (2022) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2022.105660 · Cited by 20 · see citing works

Increased Expression of T-Box Transcription Factor Protein 21 (TBX21) in Skin Cutaneous Melanoma Predicts Better Prognosis: A Study Based on The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) Databases

Zhang, X., Wen, X., Feng, N., Chen, A., Yao, S., Ding, X., & Zhang, L. (2020) · Medical Science Monitor · doi:10.12659/msm.923087 · Cited by 18 · see citing works

The vitamin D receptor Taq I polymorphism is associated with reduced VDR and increased PDIA3 protein levels in human intestinal fibroblasts

Gisbert-Ferrándiz, L., Cosín‐Roger, J., Hernández, C., Macias-Ceja, D. C., Ortiz‐Masiá, D., Salvador, P., Wildenberg, M. E., Esplugues, J. V., Alós, R., Navarro, F., et al. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2020.105720 · Cited by 18 · see citing works

Vitamin D and the aging skin: insights into oxidative stress, inflammation, and barrier function

Gao, H., Xie, T., Zhang, Y., Zhao, S., Su, L., Chen, Z., & Wang, G. (2025) · Immunity & Ageing · doi:10.1186/s12979-025-00536-6 · Cited by 23 · see citing works

Innate Lymphoid Cells in Skin Homeostasis and Malignancy

Wagner, M., & Koyasu, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.758522 · Cited by 17 · see citing works

The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism

Yang, J., Zhang, Y., Pan, Y., Sun, C., Liu, Z., Liu, N., Fu, Y., Li, X., Li, Y., & Kong, J. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.627135 · Cited by 16 · see citing works

Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy

Adamiak, K., Gaida, V. A., Schäfer, J. A., Bosse, L., Diemer, C., Reiter, R. J., Slominski, A. T., Steinbrink, K., Sionkowska, A., & Kleszczyński, K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25094858 · Cited by 16 · see citing works

Low Vitamin D Status Predicts Poor Clinical Outcome in Advanced Melanoma Treated With Immune Checkpoint or BRAF/MEK Inhibitors: A Prospective Non-Interventional Side-by-Side Analysis

Reichrath, J., Biersack, F., Wagenpfeil, S., Schöpe, J., Pföhler, C., Saternus, R., & VOGT, T. M. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.839816 · Cited by 16 · see citing works

Properties of purified CYP2R1 in a reconstituted membrane environment and its 25-hydroxylation of 20-hydroxyvitamin D3

Cheng, C. Y. S., Kim, T., Jeayeng, S., Slominski, A. T., & Tuckey, R. C. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2017.07.011 · Cited by 15 · see citing works

Vitamin D Modulates the Response of Patient-Derived Metastatic Melanoma Cells to Anticancer Drugs

Piotrowska, A., Zaucha, R., Król, O., & Zmijewski, M. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098037 · Cited by 15 · see citing works

Immunohistochemical expression of vitamin D receptor in melanocytic naevi and cutaneous melanoma: a case-control study

Puerto, C. D., Navarrete‐Dechent, C., Molgó, M., Camargo, C. A., Borzutzky, A., & González, S. (2017) · British Journal of Dermatology · doi:10.1111/bjd.16103 · Cited by 15 · see citing works

Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data

Betancourt, L. H., Pawłowski, K., Eriksson, J. O., Szász, A. M., Mitra, S., Plá, I., Welinder, C., Ekedahl, H., Broberg, P., Appelqvist, R., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-41625-z · Cited by 14 · see citing works

Analysis of local recurrence causes in uveal melanoma patients treated with 125I brachytherapy – a single institution study

Kowal, J., Markiewicz, A., Dębicka-Kumela, M., Bogdali, A. M., Jakubowska, B., Karska‐Basta, I., & Romanowska‐Dixon, B. (2019) · Journal of Contemporary Brachytherapy · doi:10.5114/jcb.2019.90985 · Cited by 14 · see citing works

Role of vitamin D serum levels in prevention of primary and recurrent melanoma

Lombardo, M., Vigezzi, A., Ietto, G., Franchi, C., Iori, V., Masci, F., Scorza, A., Macchi, S., Iovino, D., Parise, C., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-85294-3 · Cited by 13 · see citing works

Efecto de los niveles séricos de vitamina D en el pronóstico del melanoma cutáneo

Moro, R., Sánchez-Silva, A., Aguerralde‐Martin, M., González‐Cuevas, R., Peruilh‐Bagolini, L., Traves, V., Manrique‐Silva, E., Requena, C., & Nagore, E. (2021) · Actas Dermo-Sifiliográficas · doi:10.1016/j.ad.2021.11.001 · Cited by 13 · see citing works

Calcitriol Inhibits Proliferation and Potentially Induces Apoptosis in B16-F10 Cells

Sutedja, E. K., Amarassaphira, D., Goenawan, H., Pratiwi, Y. S., Sylviana, N., Setiabudiawan, B., Suwarsa, O., Judistiani, R. T. D., Supratman, U., & Lesmana, R. (2022) · Medical science monitor basic research/Medical science monitor. Basic research · doi:10.12659/msmbr.935139 · Cited by 13 · see citing works

Dissection of an impact of VDR and RXRA on the genomic activity of 1,25(OH)2D3 in A431 squamous cell carcinoma

Olszewska, A., Nowak, J. I., Myszczyński, K., Slominski, A. T., & Zmijewski, M. A. (2023) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2023.112124 · Cited by 12 · see citing works

Bufadienolides induce apoptosis and autophagy by inhibiting the AKT signaling pathway in melanoma A‑375 cells

Li, H., Cao, X., Chen, X., Yi, X., Xia, J., Chen, J., & Yang, L. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10452 · Cited by 12 · see citing works

Vitamin D Enhances Anticancer Properties of Cediranib, a VEGFR Inhibitor, by Modulation of VEGFR2 Expression in Melanoma Cells

Piotrowska, A., Beserra, F. P., Wierzbicka, J., Nowak, J. I., & Zmijewski, M. A. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.763895 · Cited by 12 · see citing works

Vitamin D insufficiency and serum levels related to the incidence and stage of cutaneous melanoma: a systematic review and meta-analysis

Shellenberger, R. A., Gowda, S., Kurn, H. A., Albright, J., & Mayo, M. (2023) · Melanoma Research · doi:10.1097/cmr.0000000000000897 · Cited by 11 · see citing works

Causal association between serum 25-Hydroxyvitamin D levels and cutaneous melanoma: a two-sample Mendelian randomization study

Cai, B., Lin, Q., Ke, R., Shan, X., Yu, J., Ni, X., Lin, X., & Wang, B. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1154107 · Cited by 11 · see citing works

Vitamin D and melanoma: state of the art and possible therapeutic uses

Paolino, G., Moliterni, E., Corsetti, P., Didona, D., Bottoni, U., Calvieri, S., & Mattozzi, C. (2019) · Giornale Italiano di Dermatologia e Venereologia · doi:10.23736/s0392-0488.17.05801-1 · Cited by 11 · see citing works

Decreased vitamin D receptor protein expression is associated with progression and poor prognosis of colorectal cancer patients.

Shi, Q., Han, X., Yu, J., Peng, H., Chen, Y., Li, F., & Cui, X. (2020) · PubMed Central · Cited by 11 · see citing works

Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria

Olszewska, A. M., & Zmijewski, M. A. (2024) · Mitochondrion · doi:10.1016/j.mito.2024.101891 · Cited by 10 · see citing works

Higher serum vitamin D concentration and supplementation were associated with improved survival outcomes and treatment response in cancer patients receiving immunotherapy: A systematic review and meta-analysis

Yang, Q., Shu, C., Li, H., Xie, X., Wu, H., Zhou, Y., Hu, H., Zhao, J., Xu, C., & He, Y. (2025) · Nutrition Research · doi:10.1016/j.nutres.2025.08.003 · Cited by 12 · see citing works

Different impact of vitamin D on mitochondrial activity and morphology in normal and malignant keratinocytes, the role of genomic pathway

Olszewska, A., Nowak, J. I., Król, O., Flis, D. J., & Zmijewski, M. A. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.11.033 · Cited by 10 · see citing works

Vitamin D resistant genes – promising therapeutic targets of chronic diseases

Milan, K. L., Jayasuriya, R., Harithpriya, K., Murugesan, A., Sarada, D. V. L., Nadhiroh, S. R., & Ramkumar, K. M. (2022) · Food & Function · doi:10.1039/d2fo00822j · Cited by 10 · see citing works

Exploring recent advances in signaling pathways and hallmarks of uveal melanoma: a comprehensive review

Banimohammad, M., Khalafi, P., Gholamin, D., Bangaleh, Z., Akhtar, N., Solomon, A. D., Prabhakar, P. K., Sanami, S., Prakash, A., & Pazoki–Toroudi, H. (2025) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2025.1002306 · Cited by 9 · see citing works

Vitamin D‐induced mechanisms in cancer prevention and therapy: Recent advances and future opportunities

Prasanth, D., Khan, P. A., Jamal‐E‐Fatima, Durgawale, T. P., Siddique, F. A., Khan, S. L., Farhana, A., Panigrahy, U. P., shahid, M. A. A., Sayeed, M., et al. (2025) · Animal Models and Experimental Medicine · doi:10.1002/ame2.70087 · Cited by 9 · see citing works

Inhibition of calcitriol inactivating enzyme CYP24A1 gene expression by flavonoids in hepatocellular carcinoma cells under normoxia and hypoxia

Angeli‐Terzidou, A., Gkotinakou, I., Pazaitou‐Panayiotou, K., & Tsakalof, A. K. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2021.108889 · Cited by 10 · see citing works

Vitamin D endocrine system in breast cancer

Linowiecka, K., Wolnicka-Głubisz, A., & Brożyna, A. A. (2021) · Acta Biochimica Polonica · doi:10.18388/abp.2020_5961 · Cited by 9 · see citing works

Antiproliferative activity of side-chain truncated vitamin D analogs (PRI-1203 and PRI-1204) against human malignant melanoma cell lines

Piotrowska, A., Wierzbicka, J., Kwiatkowska, K., Chodyński, M., Kutner, A., & Zmijewski, M. A. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173170 · Cited by 8 · see citing works

Serum Vitamin D Levels Explored in the Latvian Cohort of Patients with Basal Cell Carcinoma Linked to the Sonic Hedgehog and Vitamin D Binding Protein Cutaneous Tissue Indices

Moisejenko-Goluboviča, J., Groma, V., Svirskis, Š., & Ivanova, A. (2022) · Nutrients · doi:10.3390/nu14163359 · Cited by 8 · see citing works

Acute hepatologic and nephrologic effects of calcitriol in Syrian golden hamster (Mesocricetus auratus)

Podgórska, E., Śniegocka, M., Mycinska, M., Trybus, W., Trybus, E., Kopacz-Bednarska, A., Wiecheć-Cudak, O., Krzykawska-Serda, M., Elas, M., Król, T., et al. (2018) · Acta Biochimica Polonica · doi:10.18388/abp.2018_2626 · Cited by 8 · see citing works

Determinants of 25-hydroxyvitamin D Status in a Cutaneous Melanoma Population

Smedt, J. D., Kelst, S. V., Janssen, L., Marasigan, V., Boecxstaens, V., Stas, M., Vanderschueren, D., Guler, I., Bogaerts, K., Vandenberghe, K., et al. (2022) · Acta Dermato Venereologica · doi:10.2340/actadv.v102.262 · Cited by 7 · see citing works

Vitamin D in Melanoma: Potential Role of Cytochrome P450 Enzymes

Ben‐Eltriki, M., Gayle, E. J., Paras, J. M., Nyame-Addo, L., Chhabra, M., & Deb, S. (2024) · Life · doi:10.3390/life14040510 · Cited by 7 · see citing works

Nutrition and melanoma prevention

DeWane, M. E., Shahriari, N., & Grant-Kels, J. M. (2021) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2021.10.012 · Cited by 7 · see citing works

Exploring 2-mercapto- N -arylacetamide analogs as promising anti-melanogenic agents: in vitro and in vivo evaluation

Jung, H. J., Park, H. S., Kim, H. J., Park, H. S., Kim, Y. E., Jeong, D. E., Noh, S. G., Park, Y., Chun, P., Chung, H. Y., et al. (2024) · Organic & Biomolecular Chemistry · doi:10.1039/d4ob01225a · Cited by 6 · see citing works

The Multi-Dimensional Role of Vitamin D in the Pathophysiology and Treatment of Diabetic Foot Ulcers: From Molecular Mechanisms to Clinical Translation

Tang, W., Chen, S., Zhang, S., & Ran, X. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26125719 · Cited by 6 · see citing works

Assessment of the effect of serum and follicular fluid vitamin D and glucose on assisted reproductive technique outcome: A cross-sectional study

Hosseinisadat, R., Saeed, L., Ghasemirad, A., Habibzadeh, V., & Heidari, S. S. (2022) · International Journal of Reproductive BioMedicine (IJRM) · doi:10.18502/ijrm.v20i3.10714 · Cited by 6 · see citing works

Mechanism-based understanding of the potential cellular targets of triclosan in zebrafish larvae

Wang, F., & Liu, F. (2023) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2023.104255 · Cited by 5 · see citing works

Communication between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin

Mehrani, Y., Morovati, S., Tajik, T., Sarmadi, S., Bitaraf, A., Sourani, Z., Shahverdi, M. H., Javadi, H., Kakish, J. E., Bridle, B. W., et al. (2024) · Cells · doi:10.3390/cells13050462 · Cited by 5 · see citing works

On the role of classical and novel forms of vitamin D in melanoma progression and management

Slominski, A. T., Brożyna, A. A., Skobowiat, C., Zmijewski, M. A., Kim, T., Janjetović, Z., Oak, A. S. W., Jóźwicki, W., Jetten, A. M., Mason, R. S., et al. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2017.06.013 · Cited by 99 · see citing works

Highlights from the 20th Workshop on Vitamin D in Orlando, Mar. 28–31, 2017

Hewison, M., Fleet, J. C., Demay, M. B., Christakos, S., Bouillon, R., Welsh, J., & White, J. H. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2017.11.010 · Cited by 1 · see citing works

Relevance of Vitamin D in Melanoma Development, Progression and Therapy

Brożyna, A. A., Hoffman, R. M., & Slominski, A. T. (2019) · Anticancer Research · doi:10.21873/anticanres.13976 · Cited by 61 · see citing works

Vitamin D in Melanoma: Potential Role of Cytochrome P450 Enzymes

Ben‐Eltriki, M., Gayle, E. J., Paras, J. M., Nyame-Addo, L., Chhabra, M., & Deb, S. (2024) · Life · doi:10.3390/life14040510 · Cited by 7 · see citing works

Vitamin D–VDR Signaling Inhibits Wnt/β-Catenin–Mediated Melanoma Progression and Promotes Antitumor Immunity

Muralidhar, S., Filia, A., Nsengimana, J., Poźniak, J., O'Shea, S. J., Diaz, J. M. S., Harland, M., Randerson‐Moor, J. A., Reichrath, J., Laye, J. P., et al. (2019) · Cancer Research · doi:10.1158/0008-5472.can-18-3927 · Cited by 113 · see citing works