The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Polycomb complexes repress developmental regulators in murine embryonic stem cells
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Citations
Cites
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
Li, E., Bestor, T. H., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90611-f · Cited by 3,984
Self-citationRole of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing
Cao, R., Wang, L., Wang, H., Xia, L., Erdjument-Bromage, H., Tempst, P., Jones, R. S., & Zhang, Y. (2002) · Science · doi:10.1126/science.1076997 · Cited by 3,775
Kuzmichev, A., Nishioka, K., Erdjument-Bromage, H., Tempst, P., & Reinberg, D. (2002) · Genes & Development · doi:10.1101/gad.1035902 · Cited by 1,596
Cited by
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Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA
Jadhav, U., Cavazza, A., Banerjee, K. K., Xie, H., O’Neill, N. K., Saenz-Vash, V., Herbert, Z., Madha, S., Orkin, S. H., Zhai, H., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.02.024 · Cited by 86
Woodhouse, S., Pugazhendhi, D., Brien, P., & Pell, J. M. (2013) · Journal of Cell Science · doi:10.1242/jcs.114843 · Cited by 84
Rush, M., Appanah, R., Lee, S., Lam, L. L., Goyal, P., & Lorincz, M. C. (2009) · Epigenetics · doi:10.4161/epi.4.6.9392 · Cited by 83
Lu, R., Yang, A., & Jin, Y. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.202150 · Cited by 80
De Novo DNA Methylation Is Required to Restrict T Helper Lineage Plasticity
Thomas, R. M., Gamper, C. J., Ladle, B. H., Powell, J. D., & Wells, A. D. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.312785 · Cited by 79
The dual roles of homeobox genes in vascularization and wound healing
Kachgal, S., Mace, K. A., & Boudreau, N. J. (2012) · Cell Adhesion & Migration · doi:10.4161/cam.22164 · Cited by 72
Kyzar, E. J., Zhang, H., & Pandey, S. C. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.12.021 · Cited by 75
“The Polycomb repressive complex 2 (PRC2) adds methyl groups to H3K27, while lysine demethylase 6A (KDM6A) and KDM6B are responsible for H3K27me2/3 demethylation (27, 28).”
BackgroundHematopoietic stem cell self-renewal
Akala, O. O., & Clarke, M. F. (2006) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2006.08.011 · Cited by 75
Huseyin, M. K., & Klose, R. J. (2021) · Nature Communications · doi:10.1038/s41467-021-21130-6 · Cited by 69
Yen, A., & Kellis, M. (2015) · Nature Communications · doi:10.1038/ncomms8973 · Cited by 67
Polycomb proteins in hematologic malignancies
Martin-Perez, D., Piris, M. A., & Sanchez-Beato, M. (2010) · Blood · doi:10.1182/blood-2010-05-267096 · Cited by 65
Anterior-posterior differences in HoxD chromatin topology in limb development
Williamson, I., Eskeland, R., Lettice, L. A., Hill, A. E., Boyle, S., Grimes, G. R., Hill, R. E., & Bickmore, W. A. (2012) · Development · doi:10.1242/dev.081174 · Cited by 62
TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
Seruggia, D., Oti, M., Tripathi, P., Canver, M. C., LeBlanc, L., Di Giammartino, D. C., Bullen, M. J., Nefzger, C. M., Sun, Y. B. Y., Farouni, R., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.03.025 · Cited by 51
Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization
Tommasi, S., Zheng, A., Weninger, A., Bates, S. E., Li, X. A., Wu, X., Hollstein, M., & Besaratinia, A. (2013) · Nucleic Acids Research · doi:10.1093/nar/gks1051 · Cited by 45
Polycomb complexes redundantly maintain epidermal stem cell identity during development
Cohen, I., Bar, C., Liu, H., Valdes, V. J., Zhao, D., Galbo, P. M., Silva, J. M., Koseki, H., Zheng, D., & Ezhkova, E. (2021) · Genes & Development · doi:10.1101/gad.345363.120 · Cited by 45
Chromatin plasticity in pluripotent cells
Melcer, S., & Meshorer, E. (2010) · Essays in Biochemistry · doi:10.1042/bse0480245 · Cited by 40
Yang, L., Ma, Z., Wang, H., Niu, K., Cao, Y., Sun, L., Geng, Y., Yang, B., Gao, F., Chen, Z., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10136-w · Cited by 40
The function of chromatin modifiers in lineage commitment and cell fate specification
Signolet, J., & Hendrich, B. (2015) · The FEBS Journal · doi:10.1111/febs.13132 · Cited by 40
Grindheim, J. M., Nicetto, D., Donahue, G., & Zaret, K. S. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.01.041 · Cited by 35
Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals
Yang, J.-H., Griffin, P. T., Vera, D. L., Apostolides, J. K., Hayano, M., Meer, M. V., Salfati, E. L., Su, Q., Munding, E. M., Blanchette, M., et al. (2019) · doi:10.1101/808642 · Cited by 38
Zhu, Y., Dong, L., Wang, C., Hao, K., Wang, J., Zhao, L., Xu, L., Xia, Y., Jiang, Q., & Qin, J. (2022) · Stem Cell Reports · doi:10.1016/j.stemcr.2022.02.020 · Cited by 24
Epigenetic regulation during melanocyte development and homeostasis
Dilshat, R., Vu, H. N., & Steingrímsson, E. (2021) · Experimental Dermatology · doi:10.1111/exd.14391 · Cited by 23
Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes
Teslenko, A., & Fierz, B. (2025) · Science Advances · doi:10.1126/sciadv.adt7013 · Cited by 4
Metadata
- Authors
- Boyer, L. A., Plath, K., Zeitlinger, J., Brambrink, T., Medeiros, L. A., Lee, T. I., Levine, S. S., Wernig, M., Tajonar, A., Ray, M. K., Bell, G. W., Otte, A. P., Vidal, M., Gifford, D. K., Young, R. A., & Jaenisch, R.
- Venue
- Nature
- Published
- 2006-04-19
- Volume
- 441
- Issue
- 7091
- Pages
- 349-353
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2158610627
- Cited by
- 2,514
- References
- 3
- FWCI
- 69.37
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.