The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Dissecting self-renewal in stem cells with RNA interference
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Spatial and temporal patterns of ERK signaling during mouse embryogenesis
Corson, L. B., Yamanaka, Y., Lai, K.-M. V., & Rossant, J. (2003) · Development · doi:10.1242/dev.00669 · Cited by 390
An essential function of the mitogen‐activated protein kinase Erk2 in mouse trophoblast development
Saba‐El‐Leil, M. K., Vella, F. D. J., Vernay, B., Voisin, L., Chen, L., Labrecque, N., Ang, S., & Meloche, S. (2003) · The EMBO Reports · doi:10.1038/sj.embor.embor939 · Cited by 366
Cited by
Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y. C., Laslo, P., Cheng, J. X., Murre, C., Singh, H., & Glass, C. K. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.05.004 · Cited by 13,382
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
Guttman, M., Amit, I., Garber, M., French, C., Lin, M. F., Feldser, D., Huarte, M., Zuk, O., Carey, B. W., Cassady, J. P., et al. (2009) · Nature · doi:10.1038/nature07672 · Cited by 4,098
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation
Malta, T. M., Sokolov, A., Gentles, A. J., Burzykowski, T., Poisson, L., Weinstein, J. N., Kamińska, B., Huelsken, J., Omberg, L., Gevaert, O., et al. (2018) · Cell · doi:10.1016/j.cell.2018.03.034 · Cited by 2,180
Ito, S., D’Alessio, A. C., Taranova, O. V., Hong, K., Sowers, L. C., & Zhang, Y. (2010) · Nature · doi:10.1038/nature09303 · Cited by 2,373
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
Gupta, P. B., Fillmore, C. M., Jiang, G., Shapira, S. D., Tao, K., Kuperwasser, C., & Lander, E. S. (2011) · Cell · doi:10.1016/j.cell.2011.07.026 · Cited by 1,475
Li, R., Liang, J., Ni, S., Zhou, T., Qing, X., Li, H., He, W., Chen, J., Li, F., Zhuang, Q., et al. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.04.014 · Cited by 1,072
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
Niwa, H., Ogawa, K., Shimosato, D., & Adachi, K. (2009) · Nature · doi:10.1038/nature08113 · Cited by 872
Koh, K. P., Yabuuchi, A., Rao, S., Huang, Y., Cunniff, K., Nardone, J., Laiho, A., Tahiliani, M., Sommer, C. A., Mostoslavsky, G., et al. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.01.008 · Cited by 776
Functional annotation of native enhancers with a Cas9–histone demethylase fusion
Kearns, N. A., Pham, H., Tabak, B., Genga, R. M., Silverstein, N. J., Garber, M., & Maehr, R. (2015) · Nature Methods · doi:10.1038/nmeth.3325 · Cited by 656
An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells
van den Berg, D. L. C., Snoek, T., Mullin, N. P., Yates, A., Bezstarosti, K., Demmers, J., Chambers, I., & Poot, R. A. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.02.014 · Cited by 542
Guenther, M. G., Frampton, G. M., Soldner, F., Hockemeyer, D., Mitalipova, M., Jaenisch, R., & Young, R. A. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.06.015 · Cited by 456
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
Loh, Y.-H., Zhang, W., Chen, X., George, J., & Ng, H.-H. (2007) · Genes & Development · doi:10.1101/gad.1588207 · Cited by 443
Defining an essential transcription factor program for naïve pluripotency
Dunn, S.-J., Martello, G., Yordanov, B., Emmott, S., & Smith, A. G. (2014) · Science · doi:10.1126/science.1248882 · Cited by 370
Tbx3 improves the germ-line competency of induced pluripotent stem cells
Han, J., Yuan, P., Yang, H., Zhang, J., Soh, B. S., Li, P., Lim, S. L., Cao, S., Tay, J., Orlov, Y. L., et al. (2010) · Nature · doi:10.1038/nature08735 · Cited by 285
Graumann, J., Hubner, N. C., Kim, J. B., Ko, K., Moser, M., Kumar, C., Cox, J., Schöler, H., & Mann, M. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700460-mcp200 · Cited by 275
Mason, M. J., Fan, G., Plath, K., Zhou, Q., & Horvath, S. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-327 · Cited by 243
“of the genes whose RNAi knock down induced ES cell differentiation in Ivanova et al [4] belong to the black module (Oct4, Nanog, Sox2, Esrrb, and Dppa4, Fisher's exact”
BackgroundMethodInfluentialLineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells
Soucie, E. L., Weng, Z., Geirsdóttir, L., Molawi, K., Maurizio, J., Fenouil, R., Mossadegh-Keller, N., Gimenez, G., VanHille, L., Beniazza, M., et al. (2016) · Science · doi:10.1126/science.aad5510 · Cited by 263
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
Engelen, E., Akinci, U., Bryne, J. C., Hou, J., Gontan, C., Moen, M., Szumska, D., Kockx, C., van IJcken, W., Dekkers, D. H. W., et al. (2011) · Nature Genetics · doi:10.1038/ng.825 · Cited by 255
Zfx Controls the Self-Renewal of Embryonic and Hematopoietic Stem Cells
Galan-Caridad, J. M., Harel, S., Arenzana, T. L., Hou, Z. E., Doetsch, F. K., Mirny, L. A., & Reizis, B. (2007) · Cell · doi:10.1016/j.cell.2007.03.014 · Cited by 244
A Precarious Balance: Pluripotency Factors as Lineage Specifiers
Loh, K. M., & Lim, B. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.03.013 · Cited by 240
Lim, C. Y., Tam, W.-L., Zhang, J., Ang, H. S., Jia, H., Lipovich, L., Ng, H.-H., Wei, C.-L., Sung, W. K., Robson, P., et al. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.08.004 · Cited by 224
Di Micco, R., Fontanals-Cirera, B., Low, V., Ntziachristos, P., Yuen, S. K., Lovell, C. D., Dolgalev, I., Yonekubo, Y., Zhang, G., Rusinova, E., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.055 · Cited by 217
Guallar, D., Bi, X., Pardavila, J. A., Huang, X., Saenz, C., Shi, X., Zhou, H., Faiola, F., Ding, J., Haruehanroengra, P., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0060-9 · Cited by 190
Differential roles of Sall4 isoforms in embryonic stem cell pluripotency
Rao, S., Zhen, S., Roumiantsev, S., McDonald, L. T., Yuan, G.-C., & Orkin, S. H. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00419-10 · Cited by 173
Oct4 links multiple epigenetic pathways to the pluripotency network
Ding, J., Xu, H., Faiola, F., Ma'ayan, A., & Wang, J. (2012) · Cell Research · doi:10.1038/cr.2011.179 · Cited by 162
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain
Fasano, C. A., Phoenix, T. N., Kokovay, E., Lowry, N., Elkabetz, Y., Dimos, J. T., Lemischka, I. R., Studer, L., & Temple, S. (2009) · Genes & Development · doi:10.1101/gad.1743709 · Cited by 146
Self-citationGenome-wide prediction of transcription factor binding sites using an integrated model
Won, K.-J., Ren, B., & Wang, W. (2010) · Genome Biology · doi:10.1186/gb-2010-11-1-r7 · Cited by 116
Primary cells and stem cells in drug discovery: emerging tools for high-throughput screening
Eglen, R., & Reisine, T. (2011) · ASSAY and Drug Development Technologies · doi:10.1089/adt.2010.0305 · Cited by 100
The roles and regulation of TBX3 in development and disease
Khan, S. F., Damerell, V., Omar, R., Du Toit, M., Khan, M., Maranyane, H. M., Mlaza, M., Bleloch, J., Bellis, C., Sahm, B. D. B., et al. (2020) · Gene · doi:10.1016/j.gene.2019.144223 · Cited by 99
Lu, R., Yang, A., & Jin, Y. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.202150 · Cited by 80
Self-citationFreimer, J. W., Hu, T., & Blelloch, R. (2018) · eLife · doi:10.7554/elife.38014 · Cited by 69
A Dynamic Role of TBX3 in the Pluripotency Circuitry
Russell, R., Ilg, M., Lin, Q., Wu, G., Lechel, A., Bergmann, W., Eiseler, T., Linta, L., Kumar P., P., Klingenstein, M., et al. (2015) · Stem Cell Reports · doi:10.1016/j.stemcr.2015.11.003 · Cited by 66
Mahdavi, A., Davey, R. E., Bhola, P., Yin, T., & Zandstra, P. W. (2007) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030130 · Cited by 65
Diverse functional networks of Tbx3 in development and disease
Washkowitz, A. J., Gavrilov, S., Begum, S., & Papaioannou, V. E. (2012) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1162 · Cited by 58
Esmailpour, T., & Huang, T. (2012) · Stem Cells · doi:10.1002/stem.1187 · Cited by 54
The T-Box transcription factor 3 in development and cancer
Willmer, T., Cooper, A., Peres, J., Omar, R., & Prince, S. (2017) · BioScience Trends · doi:10.5582/bst.2017.01043 · Cited by 44
The special stemness functions of Tbx3 in stem cells and cancer development
Dong, L., Lyu, X., Faleti, O. D., & He, M.-L. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2018.09.010 · Cited by 41
Li, D., Yang, J., Huang, X., Zhou, H., & Wang, J. (2022) · Science Advances · doi:10.1126/sciadv.abm0478 · Cited by 28
Effect of Bmi1 over-expression on gene expression in adult and embryonic murine neural stem cells
Ganapathi, M., Boles, N. C., Charniga, C., Lotz, S., Campbell, M., Temple, S., & Morse, R. H. (2018) · Scientific Reports · doi:10.1038/s41598-018-25921-8 · Cited by 24
csuWGCNA: a combination of signed and unsigned WGCNA to capture negative correlations
Dai, R., Xia, Y., Liu, C., & Chen, C. (2018) · doi:10.1101/288225 · Cited by 13
Ruan, Y., Wang, J., Yu, M., Wang, F., Wang, J., Xu, Y., Liu, L., Cheng, Y., Yang, R., Zhang, C., et al. (2023) · Communications Biology · doi:10.1038/s42003-023-04700-w · Cited by 11
Single‐cell pluripotency regulatory networks
Stumpf, P. S., Ewing, R., & MacArthur, B. D. (2016) · PROTEOMICS · doi:10.1002/pmic.201500528 · Cited by 4
TBX3 stimulates proliferation and stem cell self-renewal in bladder carcinoma.
(2023) · PubMed · doi:10.14670/hh-18-496 · Cited by 4
Metadata
- Authors
- Ivanova, N., Dobrin, R., Lu, R., Kotenko, I., Levorse, J., DeCoste, C., Schafer, X., Lun, Y., & Lemischka, I. R.
- Venue
- Nature
- Published
- 2006-06-11
- Volume
- 442
- Issue
- 7102
- Pages
- 533-538
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1975200987
- Cited by
- 959
- References
- 2
- FWCI
- 32.91
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.