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Diversity, stability and resilience of the human gut microbiota
Open accessAbstract
Trillions of microbes inhabit the human intestine, forming a complex ecological community that influences normal physiology and susceptibility to disease through its collective metabolic activities and host interactions. Understanding the factors that underlie changes in the composition and function of the gut microbiota will aid in the design of therapies that target it. This goal is formidable. The gut microbiota is immensely diverse, varies between individuals and can fluctuate over time - especially during disease and early development. Viewing the microbiota from an ecological perspective could provide insight into how to promote health by targeting this microbial community in clinical treatments.
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“However, the composition of the remaining gut microbiota is remarkably diverse and dynamic, with both acute and chronic dietary exposures significantly affecting the overall microbial community (8,11).”
From The contributory role of gut microbiota in cardiovascular disease (2014) · cites this paper as [8]
In the citing paper
“We now know that the human gut harbors more than 100 trillion microbial cells, far outnumbering the human host cells of the body (8).”
From The contributory role of gut microbiota in cardiovascular disease (2014) · cites this paper as [8]
In the citing paper
“In spite of a consistency in the global composition, the intestinal microbiota seems to be highly variable among individuals at species-level phylotypes; usually Faecalibacterium prausnitzii (F.prausnitzii), Roseburia intestinalis, Bacteroides uniformis, and species of bifidobacteria and lactobacilli are present in most people [6] .”
From Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis (2014) · cites this paper as [6]
In the citing paper
“Inter-individual variation in the gut microbiota composition and gene content is known to be vast (Lozupone et al., 2012).”
From Six-Week Endurance Exercise Alters Gut Metagenome That Is not Reflected in Systemic Metabolism in Over-weight Women (2018) · cites this paper as Lozupone et al., 2012
In the citing paper
“In both a human-associated microbiota43-45 and macroecological46,47 context, higher phylogenetic diversity is associated with greater ecosystem resilience and productivity.”
From Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions (2013) · cites this paper as [45]
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“Host biology and environmental cues are both substantial contributors toward shaping gut-associated bacterial communities.3,56,57”
From Using Corticosteroids to Reshape the Gut Microbiome: Implications for Inflammatory Bowel Diseases (2015) · cites this paper as [56]
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Cites
An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
Self-citationStructure, function and diversity of the healthy human microbiome
The Human Microbiome Project Consortium (2012) · Nature · doi:10.1038/nature11234 · Cited by 11,726
Self-citationA human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624
Human gut microbes associated with obesity
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785
Self-citationDiversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913
A core gut microbiome in obese and lean twins
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823
Self-citationResilience, Adaptability and Transformability in Social–ecological Systems
Walker, B., Holling, C. S., Carpenter, S. R., & Kinzig, A. P. (2004) · Ecology and Society · doi:10.5751/es-00650-090205 · Cited by 7,821
Human gut microbiome viewed across age and geography
Yatsunenko, T., Rey, F. E., Manary, M. J., Trehan, I., Dominguez-Bello, M. G., Contreras, M., Magris, M., Hidalgo, G., Baldassano, R. N., Anokhin, A. P., et al. (2012) · Nature · doi:10.1038/nature11053 · Cited by 7,815
Self-citationEnterotypes of the human gut microbiome
MetaHIT Consortium (additional members), Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., et al. (2011) · Nature · doi:10.1038/nature09944 · Cited by 7,548
Linking long-term dietary patterns with gut microbial enterotypes
Wu, G. D., Chen, J., Hoffmann, C., Bittinger, K., Chen, Y.-Y., Keilbaugh, S. A., Bewtra, M., Knights, D., Walters, W. A., Knight, R., et al. (2011) · Science · doi:10.1126/science.1208344 · Cited by 6,513
Self-citation
Cited by
Sorted by citations
Items 801–900 of 1,040
Sex-dependent impact of Roundup on the rat gut microbiome
Lozano, V. L., Defarge, N., Rocque, L.-M., Mesnage, R., Hennequin, D., Cassier, R., de Vendômois, J. S., Panoff, J.-M., Séralini, G., & Amiel, C. (2017) · Toxicology Reports · doi:10.1016/j.toxrep.2017.12.005 · Cited by 116
Genetic risk factors for eating disorders: an update and insights into pathophysiology
Himmerich, H., Bentley, J., Kan, C., & Treasure, J. L. (2019) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125318814734 · Cited by 116
HumGut: a comprehensive human gut prokaryotic genomes collection filtered by metagenome data
Hiseni, P., Rudi, K., Wilson, R. C., Hegge, F. T., & Snipen, L. G. (2021) · Microbiome · doi:10.1186/s40168-021-01114-w · Cited by 116
Hu, B., Das, P., Lv, X., Shi, M., Aa, J., Wang, K., Duan, L., Gilbert, J. A., Nie, Y., & Wu, X. (2022) · mSystems · doi:10.1128/msystems.00218-22 · Cited by 116
High intensity perturbations induce an abrupt shift in soil microbial state
Cordero, I., Leizeaga, A., Hicks, L. C., Rousk, J., & Bardgett, R. D. (2023) · The ISME Journal · doi:10.1038/s41396-023-01512-y · Cited by 116
Kalkan, A. E., BinMowyna, M. N., Raposo, A., Ahmad, M. F., Ahmed, F., Otayf, A. Y., Carrascosa, C., Saraiva, A., & Karav, S. (2025) · Nutrients · doi:10.3390/nu17081305 · Cited by 116
Gut feelings about smoking and coffee in Parkinson's disease
Derkinderen, P., Shannon, K. M., & Brundin, P. (2014) · Movement Disorders · doi:10.1002/mds.25882 · Cited by 115
Kabbani, T. A., Pallav, K., Dowd, S. E., Villafuerte-Galvez, J., Vanga, R. R., Castillo, N. E., Hansen, J., Dennis, M., Leffler, D. A., & Kelly, C. P. (2017) · Gut Microbes · doi:10.1080/19490976.2016.1267890 · Cited by 115
Antibiotic and acid-suppression medications during early childhood are associated with obesity
Stark, C. M., Susi, A., Emerick, J., & Nylund, C. M. (2019) · Gut · doi:10.1136/gutjnl-2017-314971 · Cited by 115
Patel, S., Behara, R., Swanson, G. B., Forsyth, C. B., Voigt, R. M., & Keshavarzian, A. (2015) · Biomolecules · doi:10.3390/biom5042573 · Cited by 115
The human microbiome, asthma, and allergy
Riiser, A. (2015) · Allergy Asthma and Clinical Immunology · doi:10.1186/s13223-015-0102-0 · Cited by 115
Calcium supplementation modulates gut microbiota in a prebiotic manner in dietary obese mice
Chaplin, A. M. L., Parra, P., Laraichi, S., Serra, F. A., & Palou, A. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500480 · Cited by 115
Hamada, T., Keum, N., Nishihara, R., & Ogino, S. (2016) · Journal of Gastroenterology · doi:10.1007/s00535-016-1272-3 · Cited by 115
Bacteria isolated from lung modulate asthma susceptibility in mice
Rémot, A., Descamps, D., Noordine, M.-L., Boukadiri, A., Mathieu, E., Robert, V., Riffault, S., Lambrecht, B. N., Langella, P., Hammad, H., et al. (2017) · The ISME Journal · doi:10.1038/ismej.2016.181 · Cited by 115
Exploring the science of resilience: critical review and bibliometric analysis
Xue, X., Wang, L., & Yang, R. J. (2017) · Natural Hazards · doi:10.1007/s11069-017-3040-y · Cited by 115
Phylogenetic and Metabolic Tracking of Gut Microbiota during Perinatal Development
CHIERICO, F. D., Vernocchi, P., Petrucca, A., Paci, P., Fuentes, S., Praticò, G., Capuani, G., Masotti, A., Reddel, S., Russo, A., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0137347 · Cited by 114
Antibiotics reduce genetic diversity of core species in the honeybee gut microbiome
Raymann, K., Bobay, L., & Moran, N. A. (2017) · Molecular Ecology · doi:10.1111/mec.14434 · Cited by 114
Healthy soils for healthy plants for healthy humans
Hirt, H. (2020) · EMBO Reports · doi:10.15252/embr.202051069 · Cited by 114
Sewage reflects the distribution of human faecal L achnospiraceae
McLellan, S. L., Newton, R. J., VandeWalle, J. L., Shanks, O. C., Huse, S. M., Eren, A. M., & Sogin, M. L. (2013) · Environmental Microbiology · doi:10.1111/1462-2920.12092 · Cited by 113
Stenuit, B. A., & Agathos, S. N. (2015) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2015.03.012 · Cited by 113
Rajilić-Stojanović, M. D. (2013) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2013.03.006 · Cited by 113
Oriá, R. B., Murray‐Kolb, L. E., Scharf, R. J., Pendergast, L. L., Lang, D., Kolling, G. L., & Guerrant, R. L. (2016) · Nutrition Reviews · doi:10.1093/nutrit/nuw008 · Cited by 113
The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future
Andermann, T. M., Peled, J. U., Ho, C. M., Reddy, P. R., Riches, M., Storb, R. F., Teshima, T., van den Brink, M. R. M., Alousi, A. M., Balderman, S., et al. (2018) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2018.02.009 · Cited by 113
de la Cuesta‐Zuluaga, J., Corrales-Agudelo, V., Velásquez-Mejía, E. P., Carmona, J. A., Abad, J. M., & Escobar, J. S. (2018) · Scientific Reports · doi:10.1038/s41598-018-29687-x · Cited by 113
Valguarnera, E., Scott, N. E., Azimzadeh, P. N., & Feldman, M. F. (2018) · mSphere · doi:10.1128/msphere.00559-18 · Cited by 113
Ahlawat, S., Kumar, P., Mohan, H., Goyal, S., & Sharma, K. K. (2021) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2021.1876631 · Cited by 113
Weinstein, S. B., Martínez‐Mota, R., Stapleton, T. E., Klure, D. M., Greenhalgh, R., Orr, T. J., Dale, C., Kohl, K. D., & Dearing, M. D. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2108787118 · Cited by 113
Zhang, Y., Cao, M., Li, Y., Dai, G.-C., Lu, P., Zhang, M., Bai, L., Chen, X.-X., Zhang, C., Shi, L., et al. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2047005 · Cited by 113
Factors shaping the abundance and diversity of the gut archaeome across the animal kingdom
Thomas, C. M., Quéméner, E. D., Gribaldo, S., & Borrel, G. (2022) · Nature Communications · doi:10.1038/s41467-022-31038-4 · Cited by 113
Roles of the gut microbiome in weight management
Carmody, R. N., & Bisanz, J. E. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-023-00888-0 · Cited by 113
The gut microbiota–brain axis in neurological disorders
You, M., Chen, N., Yang, Y., Cheng, L., He, H., Cai, Y., Liu, Y., Liu, H., & Hong, G. (2024) · MedComm · doi:10.1002/mco2.656 · Cited by 113
Masanta, W. O., Heimesaat, M. M., Bereswill, S., Tareen, A. M., Lugert, R., Groß, U., & Zautner, A. E. (2013) · Clinical and Developmental Immunology · doi:10.1155/2013/526860 · Cited by 112
Xie, X., Yang, C., Guan, L. L., Wang, J., Xue, M., & Liu, J. X. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01363 · Cited by 112
Brunse, A., Martin, L., Rasmussen, T. S., Christensen, L. H., Cilieborg, M. S., Wiese, M., Khakimov, B., Pieper, R., Nielsen, D. S., Sangild, P. T., et al. (2018) · The ISME Journal · doi:10.1038/s41396-018-0301-z · Cited by 112
Nie, J., Zhang, L., Zhao, G., & Du, X. (2019) · Journal of Applied Microbiology · doi:10.1111/jam.14441 · Cited by 112
Piazzon, M. C., Naya-Català, F., Simó‐Mirabet, P., Picard‐Sánchez, A., Roig, F. J., Calduch-Giner, J. À., Sitjà‐Bobadilla, A., & Pérez‐Sánchez, J. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02512 · Cited by 112
Massimino, L., Lamparelli, L. A., Houshyar, Y., D’Alessio, S., Peyrin‐Biroulet, L., Vetrano, S., Danese, S., & Ungaro, F. (2021) · Nature Computational Science · doi:10.1038/s43588-021-00114-y · Cited by 112
The oral cavity microbiota: between health, oral disease, and cancers of the aerodigestive tract
Bars, P. L., Matamoros, S., Montassier, E., Vacon, F. L., Potel, G., Soueidan, A., Jordana, F., & de la Cochetière, M.-F. (2017) · Canadian Journal of Microbiology · doi:10.1139/cjm-2016-0603 · Cited by 111
Impact of delivery mode on the colostrum microbiota composition
Toscano, M., Grandi, R. D., Peroni, D. G., Grossi, E., Facchin, V., Comberiati, P., & Drago, L. (2017) · BMC Microbiology · doi:10.1186/s12866-017-1109-0 · Cited by 111
Li, H., Qu, J., Li, T., Wirth, S. J., Zhang, Y., Zhao, X., & Li, X. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-9097-z · Cited by 111
Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity
Zhang, X., Li, J., Krautkramer, K. A., Badri, M. H., Battaglia, T., Borbet, T. C., Koh, H., Ng, S., Sibley, R. A., Li, Y., et al. (2018) · eLife · doi:10.7554/elife.37816 · Cited by 111
Bogatyrev, S. R., Rolando, J. C., & Ismagilov, R. F. (2020) · Microbiome · doi:10.1186/s40168-020-0785-4 · Cited by 111
Kong, G., Ellul, S., Narayana, V. K., Kanojia, K., Tran, H., Li, S., Renoir, T., Cao, K. L., & Hannan, A. J. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105199 · Cited by 111
Borrego-Ruiz, A., & Borrego, J. J. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110861 · Cited by 111
Population structure of human gut bacteria in a diverse cohort from rural Tanzania and Botswana
Hansen, M. E. B., Rubel, M. A., Bailey, A. G., Ranciaro, A., Thompson, S. R., Campbell, M. C., Beggs, W., Dave, J. R., Mokone, G. G., Mpoloka, S. W., et al. (2019) · Genome Biology · doi:10.1186/s13059-018-1616-9 · Cited by 110
Alterations in Intestinal Permeability: The Role of the “Leaky Gut” in Health and Disease
Stewart, A. S., Pratt-Phillips, S. E., & Gonzalez, L. M. (2017) · Journal of Equine Veterinary Science · doi:10.1016/j.jevs.2017.02.009 · Cited by 110
Eid, H. M., Wright, M. L., Kumar, N. V. A., Qawasmeh, A., Hassan, S. T. S., Mocan, A., Nabavi, S. M., Rastrelli, L., Atanasov, A. G., & Haddad, P. S. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00387 · Cited by 110
Dopkins, N., Nagarkatti, P. S., & Nagarkatti, M. (2018) · Immunology · doi:10.1111/imm.12903 · Cited by 110
Ülker, İ., & Yıldıran, H. (2018) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.18-018 · Cited by 110
Gut Microbiota Has a Widespread and Modifiable Effect on Host Gene Regulation
Richards, A. L., Muehlbauer, A. L., Alazizi, A., Burns, M. B., Findley, A. S., Messina, F., Gould, T. J., Cascardo, C. A., Piqué-Regi, R., Blekhman, R., et al. (2019) · mSystems · doi:10.1128/msystems.00323-18 · Cited by 110
Interactions between Intestinal Microflora/Probiotics and the Immune System
Zhang, C., Wang, H., & Chen, T. (2019) · BioMed Research International · doi:10.1155/2019/6764919 · Cited by 110
The Mouse Gut Microbial Biobank expands the coverage of cultured bacteria
Liu, C., Zhou, N., Du, M., Sun, Y., Wang, K., Wang, Y., Li, D., Yu, H., Song, Y., Bai, B.-B., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13836-5 · Cited by 110
Characteristics and Dysbiosis of the Gut Microbiome in Renal Transplant Recipients
Swarte, J. C., Douwes, R. M., Hu, S., Vila, A. V., Eisenga, M. F., van Londen, M., Neto, A. W. G., Weersma, R. K., Harmsen, H. J. M., & Bakker, S. J. L. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020386 · Cited by 110
The Role of the Microbiome-Brain-Gut Axis in the Pathogenesis of Depressive Disorder
Młynarska, E., Gadzinowska, J., Tokarek, J., Forycka, J., Szuman, A., Franczyk, B., & Rysz, J. (2022) · Nutrients · doi:10.3390/nu14091921 · Cited by 109
Stothart, M. R., Bobbie, C. B., Schulte‐Hostedde, A. I., Boonstra, R., Palme, R., Mykytczuk, N., & Newman, A. E. M. (2016) · Biology Letters · doi:10.1098/rsbl.2015.0875 · Cited by 109
Deep Metaproteomics Approach for the Study of Human Microbiomes
Zhang, X., Chen, W., Ning, Z., Mayne, J., Mack, D. R., Stintzi, A., Tian, R., & Figeys, D. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b02224 · Cited by 109
Seo, D.-O., & Holtzman, D. M. (2019) · The Journals of Gerontology Series A · doi:10.1093/gerona/glz262 · Cited by 109
Depression and Obesity: Analysis of Common Biomarkers
Milano, W., Ambrosio, P., Carizzone, F., Biasio, V. D., Munzio, W. D., Foia, M. G., & Capasso, A. (2020) · Diseases · doi:10.3390/diseases8020023 · Cited by 109
Zebrafish: an efficient vertebrate model for understanding role of gut microbiota
Xia, H., Chen, H., Cheng, X., Yin, M., Yao, X., Ma, J., Huang, M., Chen, G., & Liu, H. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00579-1 · Cited by 109
Circadian regulation of liver function: from molecular mechanisms to disease pathophysiology
Bolshette, N. B., Ibrahim, H., Reinke, H., & Asher, G. (2023) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-023-00792-1 · Cited by 109
Zhong, D., Brower–Sinning, R., Firek, B., & Morowitz, M. J. (2014) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2013.06.026 · Cited by 109
The microbiome of urban waters.
McLellan, S. L., Fisher, J. C., & Newton, R. J. (2015) · PubMed · doi:10.2436/20.1501.01.244 · Cited by 109
Is there a role for gut microbiota in type 1 diabetes pathogenesis?
Bibbò, S., Dore, M. P., Pes, G. M., Delitala, G., & Delitala, A. (2016) · Annals of Medicine · doi:10.1080/07853890.2016.1222449 · Cited by 109
Brown, J. M., & Hazen, S. L. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.r116.765388 · Cited by 108
Rogier, E. W., Frantz, A. L., Bruno, M. E. C., Wedlund, L., Cohen, D. A., Stromberg, A. J., & Kaetzel, C. S. (2014) · Gut Microbes · doi:10.4161/19490976.2014.969984 · Cited by 108
Bifidobacterial Dominance of the Gut in Early Life and Acquisition of Antimicrobial Resistance
Taft, D. H., Liu, J., Maldonado-Gómez, M. X., Akre, S., Huda, M. N., Ahmad, S. M., Stephensen, C. B., & Mills, D. A. (2018) · mSphere · doi:10.1128/msphere.00441-18 · Cited by 108
Onal, E. M., Afşar, B., Covic, A. C., Vaziri, N. D., & Kanbay, M. (2018) · Hypertension Research · doi:10.1038/s41440-018-0144-z · Cited by 108
The role of diet in the prevention and treatment of Inflammatory Bowel Diseases.
Reddavide, R., Rotolo, O., Caruso, M. G., Stasi, E., Notarnicola, M., Miraglia, C., Nouvenne, A., Meschi, T., Angelis, G. L. D., Mario, F. D., et al. (2018) · Acta bio-medica dell'Ateneo parmense/Acta biomedica · doi:10.23750/abm.v89i9-s.7952 · Cited by 108
The gut microbiome in Parkinson's disease: A culprit or a bystander?
Keshavarzian, A., Engen, P. A., Bonvegna, S., & Cilia, R. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2020.01.004 · Cited by 108
Gut microbiota characteristics in mice with antibiotic-associated diarrhea
Shao, H., Zhang, C., Xiao, N., & Tan, Z. (2020) · BMC Microbiology · doi:10.1186/s12866-020-01999-x · Cited by 108
The Human Gut Phageome: Origins and Roles in the Human Gut Microbiome
Townsend, E. M., Kelly, L., Muscatt, G., Box, J. D., Hargraves, N., Lilley, D., & Jameson, E. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.643214 · Cited by 108
Giacomin, P., Zakrzewski, M., Croese, J., Su, X., Sotillo, J., McCann, L., Navarro, S., Mitreva, M., Krause, L., Loukas, A. C., et al. (2015) · Scientific Reports · doi:10.1038/srep13797 · Cited by 107
Sadabad, M. S., von Martels, J. Z. H., Khan, M. T., Blokzijl, T., Paglia, G., Dijkstra, G. D. H., Harmsen, H. J. M., & Faber, K. N. (2015) · Scientific Reports · doi:10.1038/srep17906 · Cited by 107
Lokesh, J., Kiron, V., Sipkema, D., Fernandes, J. M. O., & Moum, T. B. (2018) · MicrobiologyOpen · doi:10.1002/mbo3.672 · Cited by 107
Xenosiderophore Utilization Promotes Bacteroides thetaiotaomicron Resilience during Colitis
Zhu, W., Winter, M. G., Spiga, L., Hughes, E. R., Chanin, R. B., Mulgaonkar, A., Pennington, J., Maas, M., Behrendt, C. L., Kim, J., et al. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.01.010 · Cited by 107
Communal living: glycan utilization by the human gut microbiota
Briggs, J. A., Grondin, J. M., & Brumer, H. (2020) · Environmental Microbiology · doi:10.1111/1462-2920.15317 · Cited by 107
The Gut Microbiome of 54 Mammalian Species
de Jonge, N., Carlsen, B., Christensen, M. H., Pertoldi, C., & Nielsen, J. L. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.886252 · Cited by 107
Gut microbial DL-endopeptidase alleviates Crohn’s disease via the NOD2 pathway
Gao, J., Zhao, X., Hu, S., Huang, Z., Hu, M., Jin, S., Lu, B., Sun, K., Wang, Z., Fu, J., et al. (2022) · Cell Host & Microbe · doi:10.1016/j.chom.2022.08.002 · Cited by 107
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Bosch, J. A., Nieuwdorp, M., Zwinderman, A. H., Deschasaux, M., Radjabzadeh, D., Kraaij, R., Davids, M., de Rooij, S. R., & Lok, A. (2022) · Nature Communications · doi:10.1038/s41467-022-34504-1 · Cited by 107
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Praveen, P., Jordán, F., Priami, C., & Morine, M. J. (2015) · Microbiome · doi:10.1186/s40168-015-0104-7 · Cited by 103
Metadata
- Authors
- Lozupone, C. A., Stombaugh, J. I., Gordon, J. I., Jansson, J. K., & Knight, R.
- Affiliations
- University of Colorado Boulder (US)
- Washington University in St. Louis (US)
- Lawrence Berkeley National Laboratory (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Knight, Rob
- Venue
- Nature
- Published
- 2012-09
- Volume
- 489
- Issue
- 7415
- Pages
- 220-230
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC3577372
- OpenAlex
- W2116846792
- Cited by
- 5,533
- References
- 78
- Citations by year
- 2026: 367 · 2025: 457 · 2024: 504 · 2023: 425 · 2022: 511 · 2021: 515 · 2020: 571 · 2019: 425 · 2018: 459 · 2017: 368 · 2016: 329 · 2015: 217 · 2014: 220 · 2013: 155 · 2012: 7
- FWCI
- 17.47
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R37DK030292, K01DK090285)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Physical Sciences › Environmental Science › Ecology › Microbial Community Ecology and Physiology
- Keywords
- gut microbiota, microbial diversity, microbial community stability, microbial resilience, host-microbe interactions, microbiota composition, microbiota dynamics, disease susceptibility, early development, microbiota-targeted therapy, ecological perspective
- MeSH terms
- Diet, Environment, Health, Humans, Intestinal Mucosa, Intestines, Biodiversity, Metagenome
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