The promise and challenge of high-throughput sequencing of the antibody repertoire

Antibody therapy of cancer

Scott, A. M., Wolchok, J. D., & Old, L. J. (2012) · Nature reviews. Cancer · doi:10.1038/nrc3236 · Cited by 2,244

Predominant Autoantibody Production by Early Human B Cell Precursors

Wardemann, H., Yurasov, S., Schaefer, A., Young, J. W., Meffre, E., & Nussenzweig, M. C. (2003) · Science · doi:10.1126/science.1086907 · Cited by 2,088

Germinal Centers

Victora, G. D., & Nussenzweig, M. C. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075032 · Cited by 1,878

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Walker, L., Phogat, S., Chan-hui, P., Wagner, D., Pham, P., Goss, J. L., Wrin, T., Simek, M., Fling, S., Mitcham, J., et al. (2009) · Science · doi:10.1126/science.1178746 · Cited by 1,849

Prevalence of monoclonal gammopathy of undetermined significance

Kyle, R. A., Therneau, T. M., Rajkumar, S. V., Larson, D. R., Plevak, M. F., Offord, J. R., Dispenzieri, A., Katzmann, J. A., & Melton, L. J. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054494 · Cited by 1,423

Performance comparison of benchtop high-throughput sequencing platforms

Loman, N. J., Misra, R., Dallman, T. J., Constantinidou, C., Gharbia, S. E., Wain, J. R., & Pallen, M. J. (2012) · Nature Biotechnology · doi:10.1038/nbt.2198 · Cited by 1,383

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

Corti, D., Voss, J., Gamblin, S. J., Codoni, G., Macagno, A., Jarrossay, D., Vachieri, S. G., Pinna, D., Minola, A., Vanzetta, F., et al. (2011) · Science · doi:10.1126/science.1205669 · Cited by 1,203

Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells

Klein, U., Rajewsky, K., & Küppers, R. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.9.1679 · Cited by 1,161

Detection and quantification of rare mutations with massively parallel sequencing

Kinde, I., Wu, J., Papadopoulos, N., Kinzler, K. W., & Vogelstein, B. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105422108 · Cited by 1,144

Mass spectrometry-based de novo sequencing of the anti-FLAG-M2 antibody using multiple proteases and a dual fragmentation schemePreprint

Peng, W., Pronker, M. F., & Snijder, J. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.07.425675 · Cited by 3

Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancersPreprint

Krasik, S. V., Bryushkova, E. A., Sharonov, G. V., Myalik, D. S., Shurganova, E. V., Komarov, D. V., Shagina, I. A., Shpudeiko, P. S., Turchaninova, M. A., Vakhitova, M. T., et al. (2024) · eLife · doi:10.7554/elife.89506 · Cited by 3

De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assembliesPreprint

Beaulaurier, J., Ly, L., Duty, J. A., Tyer, C., Stevens, C. S., Hung, C.-T., Sookdeo, A., Drong, A. W., Kowdle, S., Turner, D., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.26.586834 · Cited by 3

Inferring B cell specificity for vaccines using a mixture model

Fowler, A., Galson, J. D., Trück, J., Kelly, D. F., & Lunter, G. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/464792 · Cited by 12

Prediction of antigen-responding VHH antibodies by tracking the evolution of antibody along the time course of immunization

Matsuda, T., Ogawa, Y., Komaba, L.-K., Kiyose, N., Miyazaki, N., Mizuguchi, Y., Fukuta, T., Ito, Y., & Hagihara, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1335462 · Cited by 2

Characteristics and Genomic Localization of Nurse Shark (Ginglymostoma cirratum) IgNAR

Tang, W., Zheng, K., Sun, S., Zhong, B., Luo, Z., Yang, J., Jia, L., Yang, L., Shang, W., Jiang, X., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312879 · Cited by 2

5′RACE Method for RNA-Based Sequencing of the Mouse Immunoglobulin Repertoire

Hayek, S. A., Praité, A., Lambert, J.-M., Bender, S., & Delpy, L. (2025) · Methods in molecular biology · doi:10.1007/978-1-0716-4726-4_8 · Cited by 2

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Liang, J.-Z., Wang, Y., Sun, C., Liu, T., Wu, Z.-F., Chen, L.-P., Chen, L.-N., Li, P.-L., Li, Z.-K., Zhang, C.-G., et al. (2025) · Advancement of science · doi:10.1002/advs.202508896 · Cited by 3

Integrated single-cell analyses of affinity-tested B cells enable the identification of a gene signature to predict antibody affinity

Chirichella, M., Ratcliff, M., Gu, S., Miragaia, R. J., Sammito, M. D., Cutano, V., Cohen, S. E., Angeletti, D., Ros, X. R., & Schofield, D. J. (2026) · Cell Systems · doi:10.1016/j.cels.2025.101483 · Cited by 2

Efficient Discovery of Immunoglobulin Genes for Detecting Organophosphorus Pesticides Using a Reverse Virtual Screening Pipeline

Zou, R., Guo, Y., Wang, Z., Yang, P., Liu, C., Liu, Y., Zhu, G., & Guo, Y. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.5c06597 · Cited by 2

A Prototype timsOmni Platform Enables Confident Annotation of the Key Hypervariable CDR3 Regions of IgG Immunoglobulins Using Low- and High-Energy Electron-Based Fragmentation

Ollivier, S., Schuster, D., van Rijswijck, D. M. H., Stroganova, I., Smyrnakis, A., Fiala, J., Kosmopoulou, M., Suckau, D., Pengelley, S., Raether, O., et al. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.5c07288 · Cited by 2

FvFold: A model to predict antibody Fv structure using protein language model with residual network and Rosetta minimization

Sherpa, P., Chong, K. T., & Tayara, H. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.109128 · Cited by 2

Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases

Chernigovskaya, M., Quý, K. L., Stensland, M., Singh, S. K., Nelson, R., Yilmaz, M., Kalogeropoulos, K., Sinitcyn, P. G., Patel, A. D., Castellana, N. E., et al. (2025) · Cell Systems · doi:10.1016/j.cels.2025.101449 · Cited by 2

Single-cell screening using microfluidic systems

Nainys, J., Milkus, V., & Mažutis, L. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812659-2.00013-2 · Cited by 2

Paired VH:VL Analysis of Naïve B Cell Repertoires and Comparison to Antigen-Experienced B Cell Repertoires in Healthy Human Donors

DeKosky, B. J. (2017) · Springer theses · doi:10.1007/978-3-319-58518-5_4 · Cited by 2

Development of a Rapid Identification Method for a Variety of Antibody Candidates Using High-throughput Sequencing

Ito, Y. (2017) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.16-00252-2 · Cited by 2

Probing the Antigenicity of HCV Envelope Glycoproteins by Phage Display Antibody Technology

Giang, E., Alemán, F., & Law, M. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8976-8_26 · Cited by 2

High-throughput sequencing of murine immunoglobulin heavy chain repertoires using single side unique molecular identifiers on an Ion Torrent PGM

Bürckert, J.-P., Faison, W. J., Mustin, D. E., Dubois, A. R. S. X., Sinner, R., Hunewald, O. E., Wienecke-Baldacchino, A. K., Brieger, A., & Muller, C. P. (2018) · Oncotarget · doi:10.18632/oncotarget.25493 · Cited by 2

Technologies for Making New Vaccines

Pecetta, S., Ahmed, S., Ellis, R. W., & Rappuoli, R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-79058-1.00067-0 · Cited by 2

Current advancements in B-cell receptor sequencing fast-track the development of synthetic antibodies

Gallo, E. (2024) · Molecular Biology Reports · doi:10.1007/s11033-023-08941-0 · Cited by 2

Molecular-level Antibody Repertoire Profiling and Engineering: Implications for Developing Next-generation Diagnostics, Therapeutics, and Vaccines

Lee, J. (2019) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-019-0050-5 · Cited by 2

Selection of potential cytokeratin-18 monoclonal antibodies following IGH repertoire evaluation in mice

Li, X., Zhang, W., Huang, M. N., Ren, Z., Nie, C., Liu, X., Yang, S., Zhang, X., & Yang, N. (2019) · Journal of Immunological Methods · doi:10.1016/j.jim.2019.112647 · Cited by 2

RosettaCM for antibodies with very long HCDR3s and low template availability

Kodali, P., Schoeder, C. T., Schmitz, S., Crowe, J. E., & Meiler, J. (2021) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.26166 · Cited by 2

Identification of Mouse and Human Antibody Repertoires by Next-Generation Sequencing

Sun, L., Kono, N., Toh, H., Xue, H., Sano, K., Suzuki, T., Ainai, A., Orba, Y., Yamagishi, J., Hasegawa, H., et al. (2019) · Journal of Visualized Experiments · doi:10.3791/58804-v · Cited by 2

Targeted Capture and Sequencing of Immunoglobulin Rearrangements in Multiple Myeloma to Enable Detection of Minimal Residual Disease

Chow, S. (2017) · TSpace (University of Toronto) · Cited by 2

FDA to relax grip on at-home genetic tests, but concerns linger

Ratner, M. (2018) · Nature Biotechnology · doi:10.1038/nbt0118-10 · Cited by 2

Immunoglobulin Clonotype and Ontogeny Inference

Polak, P., Mehr, R., & Yaari, G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809633-8.20249-5 · Cited by 2

Ultra-Efficient Short Read Sequencing of T Cell Receptor RepertoiresPreprint

Montagne, J. M., Zheng, X. A., Pinal‐Fernandez, I., Milisenda, J. C., Christopher‐Stine, L., Lloyd, T. E., Mammen, A. L., & Larman, H. B. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/494062 · Cited by 2

The temporal behavior of the murine T cell receptor repertoire following Immunotherapy

Snir, T., Philip, H., Gordin, M., Zilberberg, A., & Efroni, S. (2023) · Scientific Data · doi:10.1038/s41597-023-01982-x · Cited by 2

Deep Coverage and Extended Sequence Reads Obtained with a Single Archaeal Protease Expedite de novo Protein Sequencing by Mass SpectrometryPreprint

Shamorkina, T. M., Pañeda, L. P., Kadavá, T., Schulte, D., Pribil, P. A., Heidelberger, S., Narlock-Brand, A. M., Yannone, S. M., Snijder, J., & Heck, A. J. R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.26.656138 · Cited by 2

Intestinal antibody repertoire is altered by diabetes and varies depending on the pathogenesis

Chikazawa, M., & Minato, K. (2025) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2025.101964 · Cited by 1

Significance and challenges of immunopharmacogenomics

Handzha, L. H., & Nakamura, Y. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1711887 · Cited by 1

Inter-individual variability in equine antibody responses to African snake venoms follows heavy-tailed distributions with implications for antivenom production

Sánchez, A., Sánchez, P., Sánchez, A., Durán, G., Solano, G., Villalta, M., Gómez, A., Gutiérrez, J. M., & León, G. (2026) · Toxicon · doi:10.1016/j.toxicon.2026.109145 · Cited by 1

Extending Serum IgG1 Antibody Repertoire Coverage Using DIA-PTCR

Leuvenink, R. W., Wollenweber, L., Bondt, A., Fort, K. L., & Heck, A. J. R. (2026) · Journal of the American Society for Mass Spectrometry · doi:10.1021/jasms.6c00051 · Cited by 1

Deep Sequencing of T-Cell and B-Cell Receptors with Next-Generation DNA Sequencers

Jang, M., & Yew, P. Y. (2015) · Springer eBooks · doi:10.1007/978-4-431-55726-5_1 · Cited by 1

DNA Demethylation and Epigenetics

Zhang, X., Witzig, T. E., & Wu, X. (2019) · Springer eBooks · doi:10.1007/978-3-319-55530-0_120 · Cited by 1

B-Cell Receptor Features and Database Establishment in Recovered COVID-19 Patients by Combining 5'-RACE with PacBio Sequencing

Zhu, Z., Wang, P., Jia, X., Yu, M., Yan, H., Liu, L., Liu, W., Zheng, Y., Kou, G., Wang, J., et al. (2023) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2802040 · Cited by 1

Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers

Krasik, S. V., Bryushkova, E. A., Sharonov, G. V., Myalik, D. S., Shurganova, E. V., Komarov, D. V., Shagina, I. A., Shpudeiko, P. S., Turchaninova, M. A., Vakhitova, M. T., et al. (2025) · eLife · doi:10.7554/elife.89506.4 · Cited by 1

Comprehensive characterization and database construction of immune repertoire in the largest Chinese glioma cohort

Wang, L., Xu, Z., Zhang, W., Li, L., Liu, X., & Zhang, J. (2023) · iScience · doi:10.1016/j.isci.2023.108661 · Cited by 1

T-cell receptor and B-cell receptor repertoires profiling in pleural tuberculosis

Du, F., Deng, Y., Deng, L., Du, B., Xing, A., Tao, H., Li, H., Xie, L., Zhang, X., Sun, T., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1473486 · Cited by 1

Molecular characterization and complexity of the immunoglobulin repertoire in the silver-black fox (Vulpes vulpes)

Yi, X., Qiu, Y., Xie, P., Wang, S., & Sun, X. (2025) · BMC Veterinary Research · doi:10.1186/s12917-025-04676-1 · Cited by 1

Tracking B-Cell Repertoires and Clonal Histories in Normal and Malignant Lymphocytes

Weston-Bell, N. J., Cowan, G. J. M., & Sahota, S. S. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7095-7_21 · Cited by 1

High Affinity Maturated Human Antibodies from Naïve and Synthetic Antibody Repertoires

Lim, C. C., Choong, Y. S., & Lim, T. S. (2018) · InTech eBooks · doi:10.5772/intechopen.71664 · Cited by 1

Proper Read Filtering Method to Adequately Analyze Whole-Transcriptome Sequencing and RNA Based Immune Repertoire Sequencing Data for Tumor Milieu Research

Lee, S., Song, S., Yoon, S., Koh, Y., & Yun, H. (2020) · Cancers · doi:10.3390/cancers12123693 · Cited by 1

New algorithmic challenges of adaptive immune repertoire constructionPreprint

Shlemov, A., Bankevich, S., Bzikadze, A. V., & Safonova, Y. (2016) · arXiv (Cornell University) · doi:10.48550/arxiv.1604.02193 · Cited by 1

The History of Therapeutic Monoclonal Antibodies

Sodoyer, R. (2016) · Wiley eBooks · doi:10.1002/9781118940648.ch1 · Cited by 1

High-throughput sequencing of murine immunoglobulin heavy chain transcripts using single side unique molecular identifiers on an Ion Torrent PGMPreprint

Bürckert, J.-P., Faison, W. J., Dubois, A. R. S. X., Sinner, R., Hunewald, O. E., Wienecke-Baldacchino, A. K., Brieger, A., & Muller, C. P. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/219568 · Cited by 1

Quantifying evolutionary constraints on B cell affinity maturationPreprint

McCoy, C. O., Bedford, T., Minin, V. N., Bradley, P. H., Robins, H. S., & Matsen, F. A., IV (2014) · arXiv (Cornell University) · doi:10.48550/arxiv.1403.3066 · Cited by 1

Seven chain adaptive immune receptor repertoire analysis in rheumatoid arthritis: association to disease and clinically relevant phenotypesPreprint

Aterido, A., Lasanta, M. L., Blanco, F. J., Juan-Mas, A., García-Vivar, M. L., Erra, A., Pérez-García, C., Fernández, S., Sanmartí, R., Fernández‐Nebro, A., et al. (2021) · medRxiv · doi:10.1101/2021.11.26.21266347 · Cited by 1

Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancersPreprint

Krasik, S. V., Bryushkova, E. A., Sharonov, G. V., Myalik, D. S., Shurganova, E. V., Komarov, D. V., Shagina, I. A., Shpudeiko, P. S., Turchaninova, M. A., Vakhitova, M. T., et al. (2024) · eLife · doi:10.7554/elife.89506.1 · Cited by 1

Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancersPreprint

Krasik, S. V., Bryushkova, E. A., Sharonov, G. V., Myalik, D. S., Shurganova, E. V., Komarov, D. V., Shagina, I. A., Shpudeiko, P. S., Turchaninova, M. A., Vakhitova, M. T., et al. (2025) · eLife · doi:10.7554/elife.89506.3 · Cited by 1

A prototype timsOmni platform enables confident annotation of key hypervariable regions of IgG immunoglobulins using low- and high-energy electron-based fragmentationPreprint

Ollivier, S., Schuster, D., van Rijswijck, D. M. H., Stroganova, I., Smyrnakis, A., Fiala, J., Kosmopoulou, M., Suckau, D., Pengelley, S., Raether, O., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.29.685408 · Cited by 1

Quantitative mapping of antigen specificity in adaptive immune repertoire embedding spacesPreprint

Frolenkova, M., Cardente, N., Zhong, J., Egorov, E. S., Isacchini, G., Limenitakis, J. P., Fleig, P., Rawat, P., Pavlović, M., Sanetti, C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.09.692930 · Cited by 5

MOLECULAR MECHANISMS OF ANTIBODY DIVERSIFICATION IN HUMAN B-CELLS

Björkman, A. (2015) · Figshare

METHOD Open Access

Maretty, L., Sibbesen, J. A., & Krogh, A. (2014)

Fast multiclonal clusterization of V(D)J recombinations from high-throughput

Salson, M., Duez, M., Villenet, C., Caillault, A., Grardel, N., Roumier, C., Preudhomme, C., & Figeac, M. (2014)

Substitution and site-specific selection driving B cell affinity maturation is consistent across individualsPreprint

McCoy, C. O., Bedford, T., Minin, V. N., Bradley, P. H., Robins, H. S., & Matsen, F. A., IV (2014) · arXiv (Cornell University)

Microscale Technologies for High-Throughput Analysis of Immune Cells

Pogson, M., Kelton, W., & Reddy, S. T. (2015) · Springer eBooks · doi:10.1007/978-3-319-20726-1_10

Translating genomic sequences into antibody efficacy and safety against influenza toward clinical trial outcomes: a case study

Yang, H., Yang, H., Chiang, J.-H., & Wang, S.-J. (2016) · Drug Discovery Today · doi:10.1016/j.drudis.2016.06.008

Stem Cells

Handral, H. K., Sriram, G., & Cao, T. (2016) · doi:10.1002/9781119135449.ch3

On the Origin of Sequences: Computational Analysis of Somatic Hypermutation for Probabilistic Immunoglobulin Predecessor Identification

Lengerich, B. J. (2015)

Epigenetic regulation of oncogenes and tumor suppressors in chronic lymphocytic leukemia

Kopparapu, P. K. (2017) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Microfluidic Probes for Single-Cell Proteomic Analysis

Sarkar, A., Wu, L., & Han, J. (2018) · Wiley-VCH eBooks · doi:10.1002/9783527696789.ch11

In Vitro Evolution of Antibody Affinity using Libraries with Insertions and Deletions

Skamaki, K. (2017) · Apollo (University of Cambridge) · doi:10.17863/cam.33748

Disease Interception in Autoimmune Diseases: From a Conceptual Framework to Practical Implementation

Suri, A. (2019) · Wiley eBooks · doi:10.1002/9781119289234.ch1

Hidden Treasures in Contemporary RNA Sequencing

Mangul, S., Yang, H. T., Eskin, E., & Zaitlen, N. (2019) · SpringerBriefs in computer science · doi:10.1007/978-3-030-13973-5_1

Factors regulating thymic dendritic cell homeostasis and function

Spidale, N. A. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/e7q3-1e92

Engineering immunity with quantitative tools

Jewell, C. M., & Gray, J. J. (2019) · Molecular Systems Design & Engineering · doi:10.1039/c9me90024a

Functional assessment on non-neutralizing binding antibodies in the blood and genital tracts of women with breakthrough HIV infection from the CAPRISA 004 1% tenofovir gel trial.

Fisher, K. L. (2017) · ResearchSpace (University of KwaZulu-Natal)

The influence of the phylogenetic inference pipeline on murine antibody repertoire sequencing data following viral infectionPreprint

Yermanos, A., Greiff, V., Stadler, T., Oxenius, A., & Reddy, S. T. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.20.000521

Mouse-specific but infection-unspecific IgM repertoire fingerprint following viral infectionPreprint

Yermanos, A., Kräutler, N. J., Pedrioli, A., Menzel, U., Greiff, V., Stadler, T., Oxenius, A., & Reddy, S. T. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.20.000471

Caracterização da expansão de plasmoblastos e dos anticorpos deles derivados após a vacinação com 17DD e infecção natural pelo vírus da febre amarela selvagem

Marmorato, M. P. (2020) · doi:10.11606/d.5.2020.tde-07012020-132454

Scalable Models of Antibody Evolution and Benchmarking of Clonal Tree Reconstruction MethodsPreprint

Zhang, C., Bzikadze, A. V., Safonova, Y., & Mirarab, S. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.17.302505

Malaria: pathology, immune response, and vaccine design: A mini review

Pan, H. S., & Tucker, H. O. (2020) · Neurology and Neuroscience · doi:10.33425/2692-7918.1001

Gating strategy for plasmablast enumeration after hepatitis B vaccination

Byazrova, M. G., Топтыгина, А. П., Mitina, T. A., & Filatov, A. V. (2021) · Medical Immunology (Russia) · doi:10.15789/1563-0625-gsf-2066

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches

Sible, E., Zheng, S., Choi, J. E., & Vuong, B. Q. (2021) · Journal of Visualized Experiments · doi:10.3791/61551

Statistical Methods for Adaptive Immune Receptor Repertoire Analysis and Comparison

Olson, B. J. (2020) · ResearchWorks at the University of Washington (University of Washington)

Lower Somatic Mutation Levels in the λ Light-Chain Repertoires with Chronic HBV Infection

Hong, B., Liu, Q., Li, Q., Su, L., & Wang, L. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/5525369

Prediction of antigen-responding VHH antibodies by tracking evolution of antibody along time course of immunizationPreprint

Matsuda, T., Ogawa, Y., Komaba, L.-K., Kiyose, N., Miyazaki, N., Mizuguchi, Y., Fukuta, T., Ito, Y., & Hagihara, Y. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.29.449501

Characterization of the tumor-infiltrating immune repertoire in Muscle Invasive Bladder Cancer

Dorta, R. B., Yu, K., Sirota, M., Malats, N., & Pineda, S. (2021) · European Urology · doi:10.1016/s0302-2838(21)00848-4

Immunogenetics: the developmental course

Muzaffer, U., Ali, S. I., Paul, V. I., & Sheikh, W. M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-90053-9.00002-6

Mining the Associations between V(D)J Gene Segments and COVID-19 Disease Characteristics

Zhao, Y., Zhang, Y., Huang, Z.-A., Yang, F., Duan, L., & Yao, J. (2021) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm52615.2021.9669824 · Cited by 1

The Diversity and Heterogeneity of TCR and BCR in Pan-CancerPreprint

Li, B., Zhang, J., Guo, J., Hui-xue, T. A. N. G., Hu, W., Xu, L., & Chen, Y. (2021) · Research Square · doi:10.21203/rs.3.rs-926802/v1

Peer Review #1 of "DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations (v0.1)"

(2016) · PeerJ · doi:10.7287/peerj.2074v0.1/reviews/1

Background

DeKosky, B. J. (2017) · Springer theses · doi:10.1007/978-3-319-58518-5_1

Peer Review #1 of "DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations (v0.2)"

(2016) · PeerJ · doi:10.7287/peerj.2074v0.2/reviews/1

Peer Review #2 of "DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations (v0.1)"

(2016) · PeerJ · doi:10.7287/peerj.2074v0.1/reviews/2

Novel Technologies for Antibody Drug Discovery in Japan (Vol. 20, No. 08, Full Issue)

(2016) · Asia-Pacific Biotech News · doi:10.1142/s0219030316001075

DNA Demethylation and Epigenetics

Zhang, X., Witzig, T. E., & Wu, X. (2018) · Springer eBooks · doi:10.1007/978-3-319-31143-2_120-1

Faculty Opinions recommendation of Antibody repertoire analysis of hepatitis C virus infections identifies immune signatures associated with spontaneous clearance.

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(2020) · PeerJ · doi:10.7287/peerj.8370v0.1/reviews/1

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(2020) · PeerJ · doi:10.7287/peerj.8370v0.1/reviews/2

FEATURES

(2016) · Asia-Pacific Biotech News · doi:10.1142/s0219030316000562

Faculty Opinions recommendation of Phylogenetic analysis of the human antibody repertoire reveals quantitative signatures of immune senescence and aging.

Valenzano, D. R. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.727215335.793555722

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(2020) · PeerJ · doi:10.7287/peerj.8370v0.2/reviews/2

FDA raps liquid biopsy firm

(2015) · Nature Biotechnology · doi:10.1038/nbt1115-1117

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(2022) · Nature Immunology · doi:10.1038/s41590-022-01240-z

Seven Chain Adaptive Immune Receptor Repertoire Analysis in Rheumatoid Arthritis: Association to Disease and Clinically Relevant PhenotypesPreprint

Aterido, A., Lasanta, M. L., Blanco, F. J., Juan-Mas, A., García-Vivar, M. L., Erra, A., Pérez-García, C., Fernández, S., Sanmartí, R., Fernández‐Nebro, A., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3992679

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Deep Mining of Human Antibody Repertoires: Concepts, Methodologies, and Applications

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Next-generation sequencing and protein mass spectrometry for the comprehensive analysis of human cellular and serum antibody repertoires

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High-Throughput DNA Sequencing Analysis of Antibody Repertoires

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