Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007) · Cell · doi:10.1016/j.cell.2007.11.019 · Cited by 20,221

Human DNA methylomes at base resolution show widespread epigenomic differences

Lister, R., Pelizzola, M., Dowen, R. H., Hawkins, R. D., Hon, G., Tonti-Filippini, J., Nery, J. R., Lee, L., Ye, Z., Ngo, Q.-M., et al. (2009) · Nature · doi:10.1038/nature08514 · Cited by 4,673

Reprogramming of human somatic cells to pluripotency with defined factors

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Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

FUSAKI, N., BAN, H., NISHIYAMA, A., SAEKI, K., & HASEGAWA, M. (2009) · Proceedings of the Japan Academy Series B · doi:10.2183/pjab.85.348 · Cited by 1,411

Generation of human induced pluripotent stem cells from dermal fibroblasts

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Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

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The tumorigenicity of human embryonic and induced pluripotent stem cells

Ben-David, U., & Benvenisty, N. (2011) · Nature Reviews Cancer · doi:10.1038/nrc3034 · Cited by 889

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

Oskarsson, T., Acharyya, S., Zhang, X. H.-F., Vanharanta, S., Tavazoie, S. F., Morris, P. G., Downey, R. J., Manova-Todorova, K., Brogi, E., & Massagué, J. (2011) · Nature Medicine · doi:10.1038/nm.2379 · Cited by 869

Pluripotent stem cells in disease modelling and drug discovery

Avior, Y., Sagi, I., & Benvenisty, N. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2015.27 · Cited by 592

Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

Merkle, F. T., Ghosh, S., Kamitaki, N., Mitchell, J., Avior, Y., Mello, C., Kashin, S., Mekhoubad, S., Ilic, D., Charlton, M., et al. (2017) · Nature · doi:10.1038/nature22312 · Cited by 506

Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics

Chen, K. G., Mallon, B. S., McKay, R. D. G., & Robey, P. G. (2014) · Cell Stem Cell · doi:10.1016/j.stem.2013.12.005 · Cited by 358

Regulatory networks define phenotypic classes of human stem cell lines

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Genetic variability overrides the impact of parental cell type and determines iPSC differentiation potential

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Assessing the Safety of Stem Cell Therapeutics

Goldring, C. E. P., Duffy, P. A., Benvenisty, N., Andrews, P. W., Ben-David, U., Eakins, R., French, N., Hanley, N. A., Kelly, L., Kitteringham, N. R., et al. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.05.012 · Cited by 245

Teratomas from pluripotent stem cells: A clinical hurdle

Fong, C., Gauthaman, K., & Bongso, A. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22775 · Cited by 222

Histone H3 Lysine 56 Acetylation Is Linked to the Core Transcriptional Network in Human Embryonic Stem Cells

Xie, W., Song, C., Young, N. L., Sperling, A. S., Xu, F., Sridharan, R., Conway, A. E., Garcia, B. A., Plath, K., Clark, A. T., et al. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.02.004 · Cited by 197

Good Cell Culture Practice for stem cells and stem-cell-derived models

Pamies, D. (2016) · ALTEX · doi:10.14573/altex.1607121 · Cited by 160

Linking a cell-division gene and a suicide gene to define and improve cell therapy safety

Liang, Q., Monetti, C., Shutova, M. V., Neely, E. J., Hacibekiroglu, S., Yang, H., Kim, C., Zhang, P., Li, C., Nagy, K., et al. (2018) · Nature · doi:10.1038/s41586-018-0733-7 · Cited by 158

Increased Risk of Genetic and Epigenetic Instability in Human Embryonic Stem Cells Associated with Specific Culture Conditions

Garitaonandia, I., Amir, H., Boscolo, F. S., Wambua, G. K., Schultheisz, H. L., Sabatini, K., Morey, R., Waltz, S., Wang, Y.-C., Tran, H., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0118307 · Cited by 150

Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models

Wnorowski, A., Yang, H., & Wu, J. C. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.06.001 · Cited by 124

Overview: An iPS cell stock at CiRA

Umekage, M., Sato, Y., & Takasu, N. (2019) · Inflammation and Regeneration · doi:10.1186/s41232-019-0106-0 · Cited by 122

Points to Consider in the Development of Seed Stocks of Pluripotent Stem Cells for Clinical Applications: International Stem Cell Banking Initiative (ISCBI)

Andrews, P., Baker, D., Benvinisty, N., Miranda, B., Bruce, K., Br…#x00FC;stle, O., Choi, M., Choi, Y.-M., Crook, J., de Sousa, P., et al. (2015) · Regenerative Medicine · doi:10.2217/rme.14.93 · Cited by 113

Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery

Braam, S. R., Passier, R., & Mummery, C. L. (2009) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2009.07.001 · Cited by 86

OCT4 and SOX2 Work as Transcriptional Activators in Reprogramming Human Fibroblasts

Narayan, S., Bryant, G., Shah, S., Berrozpe, G., & Ptashne, M. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.07.071 · Cited by 43

In‐a‐dish: Induced pluripotent stem cells as a novel model for human diseases

Beltrão‐Braga, P. C. B., Pignatari, G. C., Russo, F. B., Fernandes, I. R., & Muotri, A. R. (2013) · Cytometry Part A · doi:10.1002/cyto.a.22231 · Cited by 30

Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture

Geens, M., Seriola, A., Barbé, L., Santalo, J., Veiga, A., Dée, K., Van Haute, L., Sermon, K., & Spits, C. (2016) · Molecular Human Reproduction · doi:10.1093/molehr/gaw004 · Cited by 26

Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells

Pistollato, F., Bal-Price, A., Coecke, S., Parvatam, S., Pamies, D., Czysz, K., Hao, J., Kee, K., Teo, A. K. K., Niu, S., et al. (2022) · Reproductive Toxicology · doi:10.1016/j.reprotox.2022.06.003 · Cited by 10