The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size

Cited by (362)

Items 101–200 of 362

  1. The RSPO‐LGR4/5‐ZNRF3/RNF43 module in liver homeostasis, regeneration, and disease
    Annunziato, Stefano, Sun, Tianliang, Tchorz, Jan S. · 2022 · Hepatology
  2. Wnt/β-Catenin signaling pathway in hepatocellular carcinoma: pathogenic role and therapeutic target
    Zekun Zhao, Tenglu Cui, Fengxian Wei, Zhiming Zhou, Yuan Sun, Chaofeng Gao, Xiaodong Xu, Huihan Zhang · 2024 · Frontiers in Oncology
  3. Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation
    Trinh, Vincent Quoc-Huy, Lee, Ting-Fang, Lemoinne, Sara, Ray, Kevin C., Ybanez, Maria D., Tsuchida, Takuma, Carter, James K., Agudo, Judith, Brown, Brian D., Akat, Kemal M. et al. · 2023 · Science Signaling
  4. Wnt/-Catenin Signaling and Liver Regeneration: Circuit, Biology, and Opportunities
    Shikai Hu, Satdarshan P. Monga · 2021 · Gene Expression
  5. The Role of Liver Zonation in Physiology, Regeneration, and Disease
    Regeant Panday, Chase P. Monckton, Salman R. Khetani · 2022 · Seminars in Liver Disease
  6. Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood haematopoietic stem cells (CB-CD34+ cells)
    Simone Perucca, Andrea Di Palma, Pier Paolo Piccaluga, Claudia Gemelli, Elisa Zoratti, Giulio Bassi, Edoardo Giacopuzzi, Andrea Lojacono, Giuseppe Borsani, Enrico Tagliafico et al. · 2017 · PLoS ONE
  7. Wnt Signaling in Adult Epithelial Stem Cells and Cancer
    Si Hui Tan, Nick Barker · 2018 · Progress in molecular biology and translational science
  8. Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury.
    Wang, Shuyong, Wang, Xuan, Shan, Yiran, Tan, Zuolong, Su, Yuxin, Cao, Yannan, Wang, Shuang, Dong, Jiahong, Gu, Jin, Wang, Yunfang · 2024 · Cell Stem Cell
  9. NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
    Kenji Namoto, Clara Baader, Vanessa Orsini, Alexandro Landshammer, Eva Breuer, Kieu Trinh Dinh, Rosemarie Ungricht, Monika Pikiolek, Stephane Laurent, Bo Lu et al. · 2024 · Cell stem cell
  10. Pericentral hepatocytes produce insulin‐like growth factor‐2 to promote liver regeneration during selected injuries in mice
    Junlai Liu, Xiao Hu, Jie Chen, Xinqi Li, Lu Wang, Binbin Wang, Wenbo Peng, Cuiwei Yang, Zhijie Li, Yan Chen et al. · 2017 · Hepatology
  11. Cellular origins of regenerating liver and hepatocellular carcinoma
    Ágnes Holczbauer, Kirk J. Wangensteen, Soona Shin · 2021 · JHEP Reports
  12. The Canonical Wnt Pathway as a Key Regulator in Liver Development, Differentiation and Homeostatic Renewal
    Sebastian L. Wild, Aya Elghajiji, Carmen Grimaldos Rodriguez, Stephen D. Weston, Zoë D. Burke, David Tosh · 2020 · Genes
  13. Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3‐Lgr4 axis
    Jonas Wizenty, Stefanie Müllerke, Marina Kolesnichenko, Julian Heuberger, Manqiang Lin, Anne‐Sophie Fischer, Hans‐Joachim Mollenkopf, Hilmar Berger, Frank Tacke, Michael J. Sigal · 2022 · The EMBO Journal
  14. Transcriptomic Dissection of Hepatocyte Heterogeneity: Linking Ploidy, Zonation, and Stem/Progenitor Cell Characteristics
    Takeshi Katsuda, Kazunori Hosaka, Juntaro Matsuzaki, Wataru Usuba, Marta Prieto‐Vila, Tomoko Yamaguchi, Atsunori Tsuchiya, Shuji Terai, Takahiro Ochiya · 2019 · Cellular and Molecular Gastroenterology and Hepatology
  15. Wnt ligand presentation and reception: from the stem cell niche to tissue engineering
    Kate M. Mills, James L. A. Szczerkowski, Shukry James Habib · 2017 · Open Biology
  16. LGR4: A New Receptor Member in Endocrine and Metabolic Diseases
    Ningning Zhang, Mingyang Yuan, Jiqiu Wang · 2023 · Endocrine Reviews
  17. Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans
    Haichuan Wang, Xinhua Song, Haotian Liao, Pan Wang, Yi Zhang, Li Che, Jie Zhang, Yi Zhou, Antonio Cigliano, Cindy Eva Ament et al. · 2020 · Hepatology
  18. The Role of LGR4 (GPR48) in Normal and Cancer Processes
    Alejandro Ordaz-Ramos, Victor Hugo Rosales-Gallegos, Jorge Meléndez-Zajgla, Vilma Maldonado, Karla Vázquez-Santillán · 2021 · International Journal of Molecular Sciences
  19. Liver Regeneration: Different Sub-Populations of Parenchymal Cells at Play Choreographed by an Injury-Specific Microenvironment
    Manco, Rita, Leclercq, Isabelle A., Clerbaux, Laure-Alix · 2018 · International Journal of Molecular Sciences
  20. β-Catenin Activation in Hepatocellular Cancer: Implications in Biology and Therapy
    Yekaterina Krutsenko, Aatur Dilip Singhi, Satdarshan P. Monga · 2021 · Cancers
  21. A Comparative Perspective on Wnt/β-Catenin Signalling in Cell Fate Determination
    Clare L. Garcin, Shukry James Habib · 2017 · Results and problems in cell differentiation
  22. Hepatic sinusoids versus central veins: Structures, markers, angiocrines, and roles in liver regeneration and homeostasis
    Ki Mark Mak, Da Wi Shin · 2020 · The Anatomical Record
  23. Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites
    Atanu Paul, Stefano Annunziato, Bo Lu, Tianliang Sun, Olivera Evrova, Lara Planas‐Paz, Vanessa Orsini, Luigi Terracciano, Olga Charlat, Zinger Yang et al. · 2022 · Nature Communications
  24. Wnt/β-Catenin Signaling in Liver Pathobiology
    Matthew D. Carson, Kari Nichole Nejak‐Bowen · 2024 · Annual Review of Pathology Mechanisms of Disease
  25. Cell fate analysis of zone 3 hepatocytes in liver injury and tumorigenesis
    Kurosaki, Shigeyuki, Nakagawa, Hayato, Hayata, Yuki, Kawamura, Satoshi, Matsushita, Yuki, Yamada, Tomoharu, Uchino, Koji, Hayakawa, Yoku, Suzuki, Nobumi, Hata, Masahiro et al. · 2021 · JHEP Reports
  26. REGγ drives Lgr5+ stem cells to potentiate radiation induced intestinal regeneration
    Xiangzhan Zhu, Minglei Yang, Zaijun Lin, Solomon Kibreab, Ya Li, Lili Zhang, Yaqi Kong, Yaodong Zhang, Yuping Ren, Jianhui Li et al. · 2021 · Science China Life Sciences
  27. Effect of Hepatic Pathology on Liver Regeneration: The Main Metabolic Mechanisms Causing Impaired Hepatic Regeneration
    Svetlana A. Rodimova, Artem M. Mozherov, Vadim V. Elagin, Maria M. Karabut, Ilia D Shchechkin, Dmitry Kozlov, Dmitry P. Krylov, Alena I. Gavrina, Nikolai Bobrov, В. Е. Загайнов et al. · 2023 · International Journal of Molecular Sciences
  28. Graphene Oxide Causes Disordered Zonation Due to Differential Intralobular Localization in the Liver
    Yakun Wu, Wenya Feng, Rui Liu, Tian Xia, Sijin Liu · 2019 · ACS Nano
  29. A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling
    Ajun Geng, Ting Hua Wu, Cheguo Cai, Wenqian Song, Jiqiu Wang, Qing Cissy Yu, Yi Arial Zeng · 2020 · eLife
  30. Challenges for the Applications of Human Pluripotent Stem Cell-Derived Liver Organoids
    Mingyang Chang, Mariia S. Bogacheva, Yan‐Ru Lou · 2021 · Frontiers in Cell and Developmental Biology
  31. Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease
    Tianyi Chen, George D. Dalton, Seh‐Hoon Oh, Raquel Maeso‐Díaz, Kuo Du, Rachel A Meyers, Cynthia D. Guy, Manal F. Abdelmalek, Ricardo Henao, Paolo Guarnieri et al. · 2022 · Cellular and Molecular Gastroenterology and Hepatology
  32. Liver organoid culture methods
    Yiqing Hu, Xiaoyi Hu, Jia Cheng Luo, Jiacheng Huang, Yaohan Sun, Haoyu Li, Yinbiao Qiao, Hao Wu, Jianhui Li, Lin Zhou et al. · 2023 · Cell & Bioscience
  33. LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation
    Joanna Filipowska, Nagesha Guthalu Kondegowda, Nancy Leon-Rivera, Sangeeta Dhawan, Rupangi C. Vasavada · 2022 · Frontiers in Endocrinology
  34. Distinct hepatocyte identities in liver homeostasis and regeneration
    Chen, Feng, Schönberger, Katharina, Tchorz, Jan S. · 2023 · JHEP Reports
  35. Determination of key events in mouse hepatocyte maturation at the single-cell level
    Yang Li, Xin Wang, Jiaxi Zheng, Ziran Xu, Lin‐Chen Li, Yulong Xiong, Bi-Chen Zhou, Jie Gao, Cheng‐Ran Xu · 2023 · Developmental Cell
  36. Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models
    Xiao Fu, James Patrick Sluka, Sherry G. Clendenon, Kenneth W. Dunn, Zemin Wang, James E. Klaunig, James A. Glazier · 2018 · PLoS ONE
  37. Environmental exposures, stem cells, and cancer
    Tasha Thong, Chanese A. Forté, Evan M. Hill, Justin A. Colacino · 2019 · Pharmacology & Therapeutics
  38. Wnt-β-catenin in hepatobiliary homeostasis, injury, and repair
    Kari Nichole Nejak‐Bowen, Satdarshan P. Monga · 2023 · Hepatology
  39. Therapeutic Innovations for Targeting Hepatoblastoma.
    Agnès Garnier, M. Ilmer, R. Kappler, M. Berger · 2016 · Anticancer Research
  40. Hepatocyte generation in liver homeostasis, repair, and regeneration
    Wenjuan Pu, Bin Zhou · 2022 · Cell Regeneration
  41. LGR4 protects hepatocytes from injury in mouse
    Ziru Li, Shiying Liu, Jianing Lou, Michael T. Mulholland, Weizhen Zhang · 2018 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  42. Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade
    Jin, Yinhua, Anbarchian, Teni, Wu, Peng, Sarkar, Abby, Fish, Matt, Peng, Weng Chuan, Nusse, Roel · 2022 · Proceedings of the National Academy of Sciences
  43. Human assembloids recapitulate periportal liver tissue in vitro
    Lei Yuan, Sagarika Dawka, Yohan Kim, Anke Liebert, Fabian Rost, Robert Arnes‐Benito, Franziska Baenke, Christina Götz, David Tsang, Andrea Schuhmann et al. · 2025 · Nature
  44. Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway
    Zoë D. Burke, Karen R. Reed, Sheng-Wen Yeh, Valérie S. Méniel, Owen James Sansom, Alan Richard Clarke, David Tosh · 2018 · Scientific Reports
  45. Novel Insights Into the Mechanism of GVHD-Induced Tissue Damage
    Takahide Ara, Daigo Hashimoto · 2021 · Frontiers in Immunology
  46. The Hepatic Central Vein: Structure, Fibrosis, and Role in Liver Biology
    Ki Mark Mak, C.Y. Maximilian Png · 2019 · The Anatomical Record
  47. Perturbed liver gene zonation in a mouse model of non-alcoholic steatohepatitis
    Zhou, Ye, Zhao, Yuanqi, Carbonaro, Marisa, Chen, Helen, Germino, Mary, Adler, Christina, Ni, Min, Zhu, Yuan O., Kim, Sun Y., Altarejos, Judith et al. · 2024 · Metabolism
  48. Controversies Surrounding the Origin of Hepatocytes in Adult Livers and the in Vitro Generation or Propagation of Hepatocytes
    Nicole Min Qian Pek, Kevin J. Liu, Massimo Nichane, Lay Teng Ang · 2020 · Cellular and Molecular Gastroenterology and Hepatology
  49. Cell and Tissue Therapy for the Treatment of Chronic Liver Disease
    Yaron Bram, Duc-Huy T. Nguyen, Vikas Gupta, Jiwoon Park, Chanel Richardson, Vasuretha Chandar, Robert E. Schwartz · 2021 · Annual Review of Biomedical Engineering
  50. Wnt/β-catenin signaling pathway in liver biology and tumorigenesis
    Shinji Matsumoto, Akira Kikuchi · 2024 · In Vitro Cellular & Developmental Biology - Animal
  51. Molecular regulation of mammalian hepatic architecture
    Stacey S. Huppert, Makiko Iwafuchi · 2018 · Current topics in developmental biology/Current Topics in Developmental Biology
  52. The Wnt/β‐catenin pathway determines the predisposition and efficiency of liver‐to‐pancreas reprogramming
    Helit Cohen, Hila Barash, Irit Meivar‐Levy, Kfir Molakandov, Marina Ben Shimon, Michael Gurevich, Fatima Zoabi, Adi Har‐Zahav, Rolf Gebhardt, Frank Gaunitz et al. · 2018 · Hepatology
  53. International Union of Basic and Clinical Pharmacology CXV: The Class F of G Protein-Coupled Receptors
    Gunnar Schulte · 2024 · Pharmacological Reviews
  54. Liver stem cells: Plasticity of the liver epithelium
    Atsunori Tsuchiya, Wei‐Yu Lu · 2019 · World Journal of Gastroenterology
  55. Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human
    Kolbe, Erik, Aleithe, Susanne, Rennert, Christiane, Spormann, Luise, Ott, Fritzi, Meierhofer, David, Gajowski, Robert, Stöpel, Claus, Hoehme, Stefan, Kücken, Michael et al. · 2019 · Cell Reports
  56. Signalling pathways and transcriptional regulators orchestrating liver development and cancer
    Campbell, Stephanie A., Stephan, Tabea L., Lotto, Jeremy, Cullum, Rebecca, Drissler, Sibyl, Hoodless, Pamela A. · 2021 · Development
  57. A spatial atlas of the healthy human liver from live donors
    Oran Yakubovsky, Keren Bahar Halpern, Sapir Shir, Roy Novoselsky, Amichay Afriat, Adi Egozi, Tal Barkai, Yotam Harnik, Rouven Hoefflin, Yael Korem Kohanim et al. · 2026 · Nature
  58. Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease
    Saponara, Enrica, Penno, Carlos, Orsini, Vanessa, Wang, Zhong-Yi, Fischer, Audrey, Aebi, Alexandra, Matadamas-Guzman, Meztli L., Brun, Virginie, Fischer, Benoit, Brousseau, Margaret et al. · 2023 · The American Journal of Pathology
  59. Liver Regeneration
    George K. Michalopoulos · 2020 · Wiley eBooks
  60. Amphiregulin mediates the hormonal regulation on Rspondin-1 expression in the mammary gland
    Cheguo Cai, Ajun Geng, Mengran Wang, Li Chun Yang, Qing Cissy Yu, Yi Arial Zeng · 2019 · Developmental Biology
  61. Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice
    Yuan Yan Sin, Laurel L. Ballantyne, Christopher R. Richmond, Colin D. Funk · 2017 · Molecular Therapy — Nucleic Acids
  62. Chemical Modulation of WNT Signaling in Cancer
    Li-shu Zhang, Lawrence Lum · 2018 · Progress in molecular biology and translational science
  63. LGR5 constitutively activates NF‐κB signaling to regulate the growth of intestinal crypts
    Shanshan Lai, Ran Cheng, Dan Gao, Ye‐Guang Chen, Cheng Deng · 2020 · The FASEB Journal
  64. Nuclear Acly protects the liver from ischemia-reperfusion injury
    Wenbin Gao, Liping Zhang, Ziru Li, Tong Wu, Chunhui Lang, Michael W. Mulholland, Weizhen Zhang · 2023 · Hepatology
  65. Phosphorylated Ezrin (Thr567) Regulates Hippo Pathway and Yes-Associated Protein (Yap) in Liver
    Yuhua Xue, Bharat Bhushan, Wendy M. Mars, William C. Bowen, Junyan Tao, Anne V. Orr, John W. Stoops, Yanping Yu, Jianhua Luo, Andrew W. Duncan et al. · 2020 · American Journal Of Pathology
  66. Controlled Functional Zonation of Hepatocytes In Vitro by Engineering of Wnt Signaling
    Tom Wahlicht, Gabrielle Vièyres, Svenja A. Bruns, Nadja Meumann, Hildegard Büning, H. Häuser, Ingo Schmitz, Thomas Pietschmann, Dagmar Wirth · 2020 · ACS Synthetic Biology
  67. Liver Endothelial Heg Regulates Vascular/Biliary Network Patterning and Metabolic Zonation Via Wnt Signaling
    Shichao Zhu, Xiyun Rao, Yude Qian, Jinbiao Chen, Renhua Song, Huili Yan, Xi Yang, Junhao Hu, Xiaohong Wang, Zhiming Han et al. · 2022 · Cellular and Molecular Gastroenterology and Hepatology
  68. Rnf43
    Stefano Serra, Runjan Chetty · 2017 · Journal of Clinical Pathology
  69. Dual-ligand engineered exosome regulates WNT signaling activation to promote liver repair and regeneration
    Lingyan Yang, Shixiang Wang, Zhiping Qiao, Yue Liu, Xu Wang, Liying Liu, Chunfang Yang, Jiying Ding, Miao Lei, Jiayi Zheng et al. · 2025 · Nature Communications
  70. Zonation, Zonation, Zonation: The Real Estate of the Liver
    Tyler M. Yasaka, C. Kim, Vik Meadows, Satdarshan P. Monga · 2025 · Annual Review of Pathology Mechanisms of Disease
  71. RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis
    Chanyi Lu, Xiaoli Lin, Jumpei Yamashita, Ranhui Xi, Minliang Zhou, Yali V. Zhang, Hong Wang, Robert F. Margolskee, Bon‐Kyoung Koo, Hans C. Clevers et al. · 2022 · Stem Cell Reports
  72. Emerging Roles for LGR4 in Organ Development, Energy Metabolism and Carcinogenesis
    Linlin Yang, Jing Wang, Xiaodi Gong, Qiong Fan, Xiaoming Yang, Yunxia Cui, Xiaoyan Gao, Lijuan Li, Xiao‐Jian Sun, Yuhong Li et al. · 2022 · Frontiers in Genetics
  73. Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis
    Antonina V. Kurtova, Melanie Heinlein, Simon F. Haas, Lars Velten, Gerrit J.P. Dijkgraaf, Elaine E. Storm, Noelyn M. Kljavin, Soufiane Boumahdi, Patricia Himmels, Aurélie Hérault et al. · 2022 · Blood Advances
  74. Multiple Facets of Cellular Homeostasis and Regeneration of the Mammalian Liver
    Stacey S. Huppert, Robert E. Schwartz · 2022 · Annual Review of Physiology
  75. Cell competition in primary and metastatic colorectal cancer
    Merel Elise van Luyk, Ana Krotenberg García, Μαρία Λάμπρου, Saskia J.E. Suijkerbuijk · 2024 · Oncogenesis
  76. GDF2 and BMP10 coordinate liver cellular crosstalk to maintain liver health
    Zhao, Dianyuan, Huang, Ziwei, Li, Xiaoyu, Wang, Huan, Hou, Qingwei, Wang, Yuyao, Yan, Fang, Yang, Wenting, Liu, Di, Yi, Shaoqiong et al. · 2024 · eLife
  77. Cellular Plasticity in Liver Regeneration
    Janina E. E. Tirnitz‐Parker, Stuart John Forbes, John Kevin Olynyk, Grant A. Ramm · 2018 · Hepatology
  78. R‑spondin family members as novel biomarkers and prognostic factors in lung cancer
    Lingzhi Wu, Weili Zhang, Jin-Xian Qian, Jian Lin Wu, Liyang Jiang, Chunhua Ling · 2019 · Oncology Letters
  79. Clinical translation of liver regeneration therapies: A conceptual road map
    Linda E. Greenbaum, Chinweike Ukomadu, Jan S. Tchorz · 2020 · Biochemical Pharmacology
  80. Design principles and therapeutic applications of novel synthetic WNT signaling agonists
    Yorick Post, Chenggang Lu, Russell B. Fletcher, Wen‐Chen Yeh, Huy Nguyen, Sung‐Jin Lee, Yang Li · 2024 · iScience
  81. Spatial hepatocyte plasticity of gluconeogenesis during the metabolic transitions between fed, fasted and starvation states
    Junichi Okada, Austin Landgraf, Alus M. Xiaoli, Li Ping Liu, Maxwell Horton, Victor L. Schuster, Fajun Yang, Simone Sidoli, Yunping Qiu, Irwin J. Kurland et al. · 2025 · Nature Metabolism
  82. PTEN-mediated AKT/β-catenin signaling enhances the proliferation and expansion of Lgr5+ hepatocytes
    Jimin Han, Kaijun Lin, Xuezheng Zhang, Lingchen Yan, Jianjun Liu, Jia Liu · 2021 · International Journal of Biological Sciences
  83. Receptor control by membrane-tethered ubiquitin ligases in development and tissue homeostasis
    Andres M. Lebensohn, J. Fernando Bazán, Rajat Rohatgi · 2022 · Current topics in developmental biology/Current Topics in Developmental Biology
  84. Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver
    Plata-Gómez, Ana Belén, de Prado-Rivas, Lucía, Sanz, Alba, Deleyto-Seldas, Nerea, García, Fernando, de la Calle Arregui, Celia, Silva, Camila, Caleiras, Eduardo, Graña-Castro, Osvaldo, Piñeiro-Yáñez, Elena et al. · 2024 · Nature Communications
  85. Hepatic Zonation in MASLD: Old Question, New Challenge in the Era of Spatial Omics
    Erika Paolini, Miriam Longo, Marica Meroni, Paola Dongiovanni · 2025 · International Journal of Molecular Sciences
  86. Tissue regeneration: Unraveling strategies for resolving pathological fibrosis
    Jiao Li, Shuyong Wang, Jie Yuan, Xiaoxu Mao, Xuan Wang, Lincheng Zhang, Qiulin Dong, Ziye Chen, Yunfang Wang, Nan Tang · 2025 · Cell stem cell
  87. The tissue-specific transcriptional landscape underlines the involvement of endothelial cells in health and disease
    Sushant Parab, Elisa Setten, Elena Astanina, Federico Bussolino, Gabriella Doronzo · 2023 · Pharmacology & Therapeutics
  88. Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase
    Gabriella Darmasaputra, Cindy C. Geerlings, Susana M. Chuva de Sousa Lopes, Hans C. Clevers, Matilde Galli · 2024 · The Journal of Cell Biology
  89. Lgr5 + cell fate regulation by coordination of metabolic nuclear receptors during liver repair
    Dan Qin, Shenghui Liu, Yuanyuan Lu, Yi Lin Yan, Jing Zhang, Shiyao Cao, Mi Chen, Ning Chen, Wendong Huang, Liqiang Wang et al. · 2022 · Theranostics
  90. The logistics of Wnt production and delivery
    Ines Alvarez‐Rodrigo, David Willnow, Jean‐Paul Vincent · 2023 · Current topics in developmental biology/Current Topics in Developmental Biology
  91. Understanding liver regeneration to bring new insights to the mechanisms driving cholangiocarcinoma
    Rachel Victoria Guest, Luke Boulter, Benjamin J. Dwyer, Stuart John Forbes · 2017 · npj Regenerative Medicine
  92. Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration
    May, Stephanie, Müller, Miryam, Livingstone, Callum R., Skalka, George L., Walsh, Peter J., Nixon, Colin, Hedley, Ann, Shaw, Robin, Clark, William, Vande Voorde, Johan et al. · 2023 · Journal of Hepatology
  93. Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver
    Adam M. Passman, Magnus J. Haughey, Emanuela Carlotti, Marc J. Williams, Biancastella Cereser, Meng‐Lay Lin, Shruthi Devkumar, Jonathan P. Gabriel, Enrico Gringeri, Umberto Cillo et al. · 2023 · Journal of Hepatology
  94. Transforming growth factor‐β signaling confers hepatic stellate cells progenitor features after partial hepatectomy
    Zixin Chen, Li Wan, Xin Jin, Wei Wang, Dewei Li · 2019 · Journal of Cellular Physiology
  95. Targeting the Wnt signaling pathway: the challenge of reducing scarring without affecting repair
    Edward J. Jarman, Luke Boulter · 2020 · Expert Opinion on Investigational Drugs
  96. ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
    Rozenn Riou, Meriem Ladli, Sabine Gerbal‐Chaloin, Pascale Bossard, Angélique Gougèlet, Cécile Godard, Robin Loesch, Isabelle Lagoutte, Franck Lager, Julien Caldéraro et al. · 2020 · eLife
  97. Effects of watercress extract fraction on R‐spondin 1‐mediated growth of human hair
    Masakazu Hashimoto, Yuka Kawai, Teruaki Masutani, Kiyotaka Tanaka, Kenichi Ito, Arunasiri Iddamalgoda · 2022 · International Journal of Cosmetic Science
  98. Hear the sounds: the role of G protein-coupled receptors in the cochlea
    Zhong Zhang, Renjie Chai · 2022 · American Journal of Physiology-Cell Physiology
  99. In vivo partial reprogramming by bacteria promotes adult liver organ growth without fibrosis and tumorigenesis
    Samuel Hess, Timothy James Kendall, Maria T. Peña, Keitaro Yamane, Daniel Y. H. Soong, Linda B. Adams, Richard W. Truman, Anura Rambukkana · 2022 · Cell Reports Medicine
  100. Intrinsic disorder in spondins and some of their interacting partners
    Oluwole Alowolodu, Gbemisola Johnson, Lamis Alashwal, Iqbal Addou, Irina V. Zhdanova, Vladimir Nikolaevich Uversky · 2016 · Intrinsically Disordered Proteins