The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes
Open accessAbstract
Polyploidization has provided much genetic variation for plant adaptive evolution, but the mechanisms by which the molecular evolution of polyploid genomes establishes genetic architecture underlying species differentiation are unclear. Brassica is an ideal model to increase knowledge of polyploid evolution. Here we describe a draft genome sequence of Brassica oleracea, comparing it with that of its sister species B. rapa to reveal numerous chromosome rearrangements and asymmetrical gene loss in duplicated genomic blocks, asymmetrical amplification of transposable elements, differential gene co-retention for specific pathways and variation in gene expression, including alternative splicing, among a large number of paralogous and orthologous genes. Genes related to the production of anticancer phytochemicals and morphological variations illustrate consequences of genome duplication and gene divergence, imparting biochemical and morphological variation to B. oleracea. This study provides insights into Brassica genome evolution and will underpin research into the many important crops in this genus. Brassica oleracea is plant species comprising economically important vegetable crops. Here, the authors report the draft genome sequence of B. oleracea and, through a comparative analysis with the closely related B. rapa, reveal insights into Brassicaevolution and divergence of interspecific genomes and intraspecific subgenomes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482
Tamura, K., Peterson, D., Peterson, N., Stecher, G., Nei, M., & Kumar, S. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr121 · Cited by 39,969
Kimura, M. (1980) · Journal of Molecular Evolution · doi:10.1007/bf01731581 · Cited by 29,778
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
Tamura, K., Dudley, J., Nei, M., & Kumar, S. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msm092 · Cited by 28,730
Clustal W and Clustal X version 2.0
Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A., Lopez, R., et al. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btm404 · Cited by 28,358
Trapnell, C., Roberts, A., Goff, L., Pertea, G., Kim, D., Kelley, D. R., Pimentel, H., Salzberg, S. L., Rinn, J. L., & Pachter, L. (2012) · Nature Protocols · doi:10.1038/nprot.2012.016 · Cited by 12,116
tRNAscan-SE: A Program for Improved Detection of Transfer RNA Genes in Genomic Sequence
Lowe, T. M., & Eddy, S. R. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.5.955 · Cited by 10,905
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
Initiative, T. A. G. (2000) · Nature · doi:10.1038/35048692 · Cited by 9,301
OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes
Li, L., Stoeckert, C. J., & Roos, D. S. (2003) · Genome Research · doi:10.1101/gr.1224503 · Cited by 5,707
The tomato genome sequence provides insights into fleshy fruit evolution
The Tomato Genome Consortium (2012) · Nature · doi:10.1038/nature11119 · Cited by 3,289
A unified classification system for eukaryotic transposable elements
Wicker, T., Sabot, F., Hua-Van, A., Bennetzen, J. L., Capy, P., Chalhoub, B., Flavell, A., Leroy, P., Morgante, M., Panaud, O., et al. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2165 · Cited by 3,054
Self-citationBirney, E., Clamp, M., & Durbin, R. (2004) · Genome Research · doi:10.1101/gr.1865504 · Cited by 2,542
BIOLOGY AND BIOCHEMISTRY OF GLUCOSINOLATES
Halkier, B. A., & Gershenzon, J. (2006) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105228 · Cited by 2,271
Ancestral polyploidy in seed plants and angiosperms
Jiao, Y., Wickett, N. J., Ayyampalayam, S., Chanderbali, A. S., Landherr, L., Ralph, P. E., Tomsho, L. P., Hu, Y., Liang, H., Soltis, P. S., et al. (2011) · Nature · doi:10.1038/nature09916 · Cited by 2,226
The genome of the mesopolyploid crop species Brassica rapa
The Brassica rapa Genome Sequencing Project Consortium, Wang, X., Wang, H., Wang, J., Sun, R., Wu, J., Liu, S., Bai, Y., Mun, J.-H., Bancroft, I., et al. (2011) · Nature Genetics · doi:10.1038/ng.919 · Cited by 2,074
Self-citationTigrScan and GlimmerHMM: two open source ab initio eukaryotic gene-finders
Majoros, W. H., Pertea, M., & Salzberg, S. L. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth315 · Cited by 1,934
Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events
Bowers, J. E., Chapman, B. A., Rong, J., & Paterson, A. H. (2003) · Nature · doi:10.1038/nature01521 · Cited by 1,599
Self-citationInfernal 1.0: inference of RNA alignments
Nawrocki, E. P., Kolbe, D. L., & Eddy, S. R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp157 · Cited by 1,436
AUGUSTUS: a web server for gene finding in eukaryotes
Stanke, M., Steinkamp, R., Waack, S., & Morgenstern, B. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh379 · Cited by 1,334
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
HIGDON, J., DELAGE, B., WILLIAMS, D., & DASHWOOD, R. (2007) · Pharmacological Research · doi:10.1016/j.phrs.2007.01.009 · Cited by 1,039
The genome of the pear (Pyrus bretschneideri Rehd.)
Wu, J., Wang, Z., Shi, Z., Zhang, S., Ming, R., Zhu, S., Khan, M. A., Tao, S., Korban, S. S., Wang, H., et al. (2013) · Genome Research · doi:10.1101/gr.144311.112 · Cited by 1,037
Self-citationFreeling, M. (2009) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.043008.092122 · Cited by 1,015
Genome-wide mapping of alternative splicing in Arabidopsis thaliana
Filichkin, S. A., Priest, H. D., Givan, S. A., Shen, R., Bryant, D. W., Fox, S. E., Wong, W.-K., & Mockler, T. C. (2010) · Genome Research · doi:10.1101/gr.093302.109 · Cited by 905
Estimating Maximum Likelihood Phylogenies with PhyML
Guindon, S., Delsuc, F., Dufayard, J.-F., & Gascuel, O. (2009) · Methods in Molecular Biology · doi:10.1007/978-1-59745-251-9_6 · Cited by 820
Differentiation of the maize subgenomes by genome dominance and both ancient and ongoing gene loss
Schnable, J. C., Springer, N. M., & Freeling, M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101368108 · Cited by 708
Genome Size Reduction through Illegitimate Recombination Counteracts Genome Expansion in Arabidopsis
Devos, K. M., Brown, J. K. M., & Bennetzen, J. L. (2002) · Genome Research · doi:10.1101/gr.132102 · Cited by 685
Evolutionary Genetics of Genome Merger and Doubling in Plants
Doyle, J. J., Flagel, L. E., Paterson, A. H., Rapp, R. A., Soltis, D. E., Soltis, P. S., & Wendel, J. F. (2008) · Annual Review of Genetics · doi:10.1146/annurev.genet.42.110807.091524 · Cited by 684
Self-citationChromosome triplication found across the tribe Brassiceae
Lysak, M. A., Koch, M. A., Pecinka, A., & Schubert, I. (2005) · Genome Research · doi:10.1101/gr.3531105 · Cited by 672
Molecular mechanisms of polyploidy and hybrid vigor
Chen, Z. J. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2009.12.003 · Cited by 609
The ABC’s of comparative genomics in the Brassicaceae: building blocks of crucifer genomes
Schranz, M. E., Lysak, M. A., & Mitchell-Olds, T. (2006) · Trends in Plant Science · doi:10.1016/j.tplants.2006.09.002 · Cited by 575
Parkin, I. A. P., Gulden, S. M., Sharpe, A. G., Lukens, L., Trick, M., Osborn, T. C., & Lydiate, D. J. (2005) · Genetics · doi:10.1534/genetics.105.042093 · Cited by 571
Self-citationSulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells
Li, Y., Zhang, T., Korkaya, H., Liu, S., Lee, H.-F., Newman, B., Yu, Y., Clouthier, S. G., Schwartz, S. J., Wicha, M. S., et al. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-2937 · Cited by 559
Self-citationAnalyses of LTR-Retrotransposon Structures Reveal Recent and Rapid Genomic DNA Loss in Rice
Ma, J., Devos, K. M., & Bennetzen, J. L. (2004) · Genome Research · doi:10.1101/gr.1466204 · Cited by 548
Self-citationAlternative splicing in plants – coming of age
Syed, N. H., Kalyna, M., Marquez, Y., Barta, A., & Brown, J. W. S. (2012) · Trends in Plant Science · doi:10.1016/j.tplants.2012.06.001 · Cited by 509
Town, C. D., Cheung, F., Maiti, R., Crabtree, J., Haas, B. J., Wortman, J. R., Hine, E. E., Althoff, R., Arbogast, T. S., Tallon, L. J., et al. (2006) · The Plant Cell · doi:10.1105/tpc.106.041665 · Cited by 421
Self-citationAn Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming
Gabut, M., Samavarchi-Tehrani, P., Wang, X., Slobodeniuc, V., O'Hanlon, D., Sung, H.-K., Alvarez, M., Talukder, S., Pan, Q., Mazzoni, E. O., et al. (2011) · Cell · doi:10.1016/j.cell.2011.08.023 · Cited by 373
Self-citationDeciphering the Diploid Ancestral Genome of the Mesohexaploid Brassica rapa
Cheng, F., Mandáková, T., Wu, J., Xie, Q., Lysak, M. A., & Wang, X. (2013) · The Plant Cell · doi:10.1105/tpc.113.110486 · Cited by 353
Self-citationLTR_STRUC: a novel search and identification program for LTR retrotransposons
McCarthy, E. M., & McDonald, J. F. (2003) · Bioinformatics · doi:10.1093/bioinformatics/btf878 · Cited by 336
Creating a honey bee consensus gene set
Elsik, C. G., Mackey, A. J., Reese, J. T., Milshina, N. V., Roos, D. S., & Weinstock, G. M. (2007) · Genome Biology · doi:10.1186/gb-2007-8-1-r13 · Cited by 326
Woodhouse, M. R., Schnable, J. C., Pedersen, B. S., Lyons, E., Lisch, D., Subramaniam, S., & Freeling, M. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000409 · Cited by 325
The fate of duplicated genes in a polyploid plant genome
Roulin, A., Auer, P. L., Libault, M., Schlueter, J., Farmer, A., May, G., Stacey, G., Doerge, R. W., & Jackson, S. A. (2013) · The Plant Journal · doi:10.1111/tpj.12026 · Cited by 302
Positive selection driving diversification in plant secondary metabolism
Benderoth, M., Textor, S., Windsor, A. J., Mitchell-Olds, T., Gershenzon, J., & Kroymann, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601738103 · Cited by 227
Mun, J.-H., Kwon, S.-J., Yang, T.-J., Seol, Y.-J., Jin, M., Kim, J.-A., Lim, M.-H., Kim, J. S., Baek, S., Choi, B.-S., et al. (2009) · Genome Biology · doi:10.1186/gb-2009-10-10-r111 · Cited by 224
Self-citationDissecting the genome of the polyploid crop oilseed rape by transcriptome sequencing
Bancroft, I., Morgan, C., Fraser, F., Higgins, J., Wells, R., Clissold, L., Baker, D., Long, Y., Meng, J., Wang, X., et al. (2011) · Nature Biotechnology · doi:10.1038/nbt.1926 · Cited by 214
Self-citationPanjabi, P., Jagannath, A., Bisht, N. C., Padmaja, K. L., Sharma, S., Gupta, V., Pradhan, A. K., & Pental, D. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-113 · Cited by 211
Cheung, F., Trick, M., Drou, N., Lim, Y. P., Park, J.-Y., Kwon, S.-J., Kim, J.-A., Scott, R., Pires, J. C., Paterson, A. H., et al. (2009) · The Plant Cell · doi:10.1105/tpc.108.060376 · Cited by 184
Self-citationAccumulation and bioavailability of dietary carotenoids in vegetable crops
KOPSELL, D., & KOPSELL, D. (2006) · Trends in Plant Science · doi:10.1016/j.tplants.2006.08.006 · Cited by 182
Lysak, M. A., Cheung, K., Kitschke, M., & Bureš, P. (2007) · Plant Physiology · doi:10.1104/pp.107.104380 · Cited by 177
Glucosinolate biosynthetic genes in Brassica rapa
Wang, H., Wu, J., Sun, S., Liu, B., Cheng, F., Sun, R., & Wang, X. (2011) · Gene · doi:10.1016/j.gene.2011.07.021 · Cited by 155
Self-citationVolden, J., Borge, G. I. A., Hansen, M. K., Wicklund, T., & Bengtsson, G. (2008) · LWT · doi:10.1016/j.lwt.2008.05.018 · Cited by 140
The collapse of gene complement following whole genome duplication
Sankoff, D., Zheng, C., & Zhu, Q. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-313 · Cited by 124
Structure-based discovery and description of plant and animal Helitrons
Yang, L., & Bennetzen, J. L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905563106 · Cited by 120
Self-citationTesting the Ratio of Two Poisson Rates
Gu, K., Ng, H. K. T., Tang, M., & Schucany, W. R. (2008) · Biometrical Journal · doi:10.1002/bimj.200710403 · Cited by 112
Lou, P., Wu, J., Cheng, F., et al. (2012) · The Plant Cell · doi:10.1105/tpc.112.099499 · Cited by 111
Self-citationWang, X., Tang, H., & Paterson, A. H. (2011) · The Plant Cell · doi:10.1105/tpc.110.080622 · Cited by 91
Self-citationThe Transposable Element Landscape of the Model LegumeLotus japonicus
Nagel, D. H., Zhang, X., Jiang, N., Pritham, E. J., & Wessler, S. R. (2006) · Genetics · doi:10.1534/genetics.106.062752 · Cited by 90
Wang, W., Huang, S., Liu, Y., Fang, Z., Yang, L., Hua, W., Yuan, S., Liu, S., Sun, J., Zhuang, M., et al. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-523 · Cited by 82
Self-citationZhang, P. G. Y., Huang, S. Z., Pin, A.-L., & Adams, K. L. (2010) · Molecular Biology and Evolution · doi:10.1093/molbev/msq054 · Cited by 67
Self-citationMethylthioalkylmalate synthases: genetics, ecology and evolution
Benderoth, M., Pfalz, M., & Kroymann, J. (2008) · Phytochemistry Reviews · doi:10.1007/s11101-008-9097-1 · Cited by 56
Khwaja, F. S., Wynne, S., Posey, I., et al. (2009) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-08-0202 · Cited by 28
Wang, X., Torres, M. J., Pierce, G. J., Lemke, C., Nelson, L. K., Yüksel, B., Bowers, J., Marler, B. S., Xiao, Y., Lin, L., et al. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-470 · Cited by 24
Self-citation
Cited by
Albalat, R., & Cañestro, C. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2016.39 · Cited by 775
Yang, J., Liu, D., Wang, X., Ji, C., Cheng, F., Liu, B., Hu, Z., Chen, S., Pental, D., Ju, Y., et al. (2016) · Nature Genetics · doi:10.1038/ng.3657 · Cited by 580
Self-citationWhole-genome resequencing reveals Brassica napus origin and genetic loci involved in its improvement
Lu, K., Wei, L., Li, X., Wang, Y., Wu, J., Liu, M., Zhang, C., Chen, Z., Xiao, Z., Jian, H., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09134-9 · Cited by 417
Self-citationGene retention, fractionation and subgenome differences in polyploid plants
Cheng, F., Wu, J., Cai, X., Liang, J., Freeling, M., & Wang, X. (2018) · Nature Plants · doi:10.1038/s41477-018-0136-7 · Cited by 398
Self-citationCheng, F., Sun, R., Hou, X., Zheng, H., Zhang, F., Zhang, Y., Liu, B., Liang, J., Zhuang, M., Liu, Y., et al. (2016) · Nature Genetics · doi:10.1038/ng.3634 · Cited by 382
Self-citation
Metadata
- Authors
- Liu, S., Liu, Y., Yang, X., Tong, C., Edwards, D., Parkin, I. A. P., Zhao, M., Ma, J., Yu, J., Huang, S., Wang, X., Wang, J., Lu, K., Fang, Z., Bancroft, I., Yang, T.-J., Hu, Q., Wang, X., Yue, Z., Li, H., Yang, L., Wu, J., Zhou, Q., Wang, W., King, G. J., Pires, J. C., Lu, C., Wu, Z., Sampath, P., Wang, Z., Guo, H., Pan, S., Yang, L., Min, J., Zhang, D., Jin, D., Li, W., Belcram, H., Tu, J., Guan, M., Qi, C., Du, D., Li, J., Jiang, L., Batley, J., Sharpe, A. G., Park, B.-S., Ruperao, P., Cheng, F., Waminal, N. E., Huang, Y., Dong, C., Wang, L., Li, J., Hu, Z., Zhuang, M., Huang, Y., Huang, J., Shi, J., Mei, D., Liu, J., Lee, T.-H., Wang, J., Jin, H., Li, Z., Li, X., Zhang, J., Xiao, L., Zhou, Y., Liu, Z., Liu, X., Qin, R., Tang, X., Liu, W., Wang, Y., Zhang, Y., Lee, J., Kim, H. H., Denoeud, F., Xu, X., Liang, X., Hua, W., Wang, X., Wang, J., Chalhoub, B., & Paterson, A. H.
- Venue
- Nature Communications
- Published
- 2014-05-23
- Volume
- 5
- Issue
- 1
- Pages
- 3930-3930
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W1991552254
- Cited by
- 1,161
- References
- 62
- FWCI
- 106.68
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.