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THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

Tran, Pamela V, Haycraft, Courtney J, Besschetnova, Tatiana Y, Turbe-Doan, Annick, Stottmann, Rolf W, Herron, Bruce J, Chesebro, Allyson L, Qiu, Haiyan, Scherz, Paul J, Shah, Jagesh V, Yoder, Bradley K, Beier, David R·2008·Nature Genetics
DOI 10.1038/ng.105
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Research works printed but not linked: 39

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  3. Liu, A., Wang, B. & Niswander, L.A. Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132, 3103–3111 (2005). · DOI · Paper page
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  15. Zhang, X.M., Ramalho-Santos, M. & McMahon, A.P. Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell 106, 781–792 (2001). · DOI
  16. Mo, R. et al. Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development 124, 113–123 (1997). · DOI
  17. Ding, Q. et al. Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development 125, 2533–2543 (1998). · DOI
  18. Litingtung, Y., Dahn, R.D., Li, Y., Fallon, J.F. & Chiang, C. Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity. Nature 418, 979–983 (2002). · DOI
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  20. Wang, C., Ruther, U. & Wang, B. The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev. Biol. 305, 460–469 (2007). · DOI
  21. Follit, J.A., Tuft, R.A., Fogarty, K.E. & Pazour, G.J. The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly. Mol. Biol. Cell 17, 3781–3792 (2006). · DOI
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Metadata

Authors
Tran, P. V., Haycraft, C. J., Besschetnova, T. Y., Turbe-Doan, A., Stottmann, R. W., Herron, B. J., Chesebro, A. L., Qiu, H., Scherz, P. J., Shah, J. V., Yoder, B. K., & Beier, D. R.
Venue
Nature Genetics
Publisher
Springer Science and Business Media LLC
Published
2008-03-09
Volume
40
Issue
4
Pages
403-410
ISSN
  • 1061-4036
  • 1546-1718
DOI
10.1038/ng.105
Cited by
322
References
6
Language
en
Licence
www.springer.com/tdm (tdm)

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