The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

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The Role of CARD9 in Metabolic Diseases

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AIM2 promotes TH17 cells differentiation by regulating RORγt transcription activity

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The roles of AIM2 in neurodegenerative diseases: insights and therapeutic implications

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Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV)

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Promiscuous Inflammasomes: The False Dichotomy of RNA/DNA Virus-Induced Inflammasome Activation and Pyroptosis

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The Role of Neutrophils in Lower Limb Peripheral Artery Disease: State of the Art and Future Perspectives

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Nonreceptor Tyrosine Kinase c-Abl– and Arg-Mediated IRF3 Phosphorylation Regulates Innate Immune Responses by Promoting Type I IFN Production

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The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct α2–α3 helix conformation from its human homologues

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PANoptosis as a drug discovery framework: integrating cell death architecture with clinical translation

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Viroporins Manipulate Cellular Powerhouses and Modulate Innate Immunity

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Identification and Validation of PKR as a Direct Target for the Novel Sulfonamide-Substituted Tetrahydroquinoline Nonselective Inhibitor of the NLRP3 Inflammasome

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AIM2 enhances Candida albicans infection through promoting macrophage apoptosis via AKT signaling

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DNA damage-induced AIM2 pyroptosis in high glucose-induced proximal tubular epithelial cell

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Inhibition of IFNAR-JAK signaling enhances tolerability and transgene expression of systemic non-viral DNA delivery

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Crystallographic characterization of mouse AIM2 HIN-200 domain bound to a 15 bp and an 18 bp double-stranded DNA

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AIM2 Inflammasome Is Critical for dsDNA-Induced IL-1β Secretion in Human Dental Pulp Cells

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Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model

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The cytosolic DNA sensor AIM2 promotes Helicobacter‐induced gastric pathology via the inflammasome

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Aging and the Inflammasomes

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Cell-Autonomous Responses in Listeria monocytogenes Infection

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Nucleic Acid Adjuvants

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Inflammation initiated by stressed organelles

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Optimized protocols for studying the NLRP3 inflammasome and assessment of potential targets of CP-453,773 in undifferentiated THP1 cells

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Activation of inflammasomes and mechanisms for intracellular recognition of Listeria monocytogenes

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Controlling viral inflammatory lesions by rebalancing immune response patterns

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Inflammasomes: emerging therapeutic targets in hidradenitis suppurativa?

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Shengmai-Yin resists myocardial ischemia reperfusion injury by inhibiting K27 ubiquitination of absent in melanoma 2

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A short history of the atrial NLRP3 inflammasome and its distinct role in atrial fibrillation

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LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules

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Targeting innate immune sensors for therapeutic strategies in infectious diseases

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Inflammasomes in antiviral immunity: clues for influenza vaccine development

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Monophosphoryl Lipid A Enhances Efficacy of a Francisella tularensis LVS-Catanionic Nanoparticle Subunit Vaccine against F. tularensis Schu S4 Challenge by Augmenting both Humoral and Cellular Immunity

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Significant difference of differential expression pyroptosis-related genes and their correlations with infiltrated immune cells in sepsis

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Elevated expression of the AIM2 gene in response to Helicobacter pylori along with the decrease of NLRC4 inflammasome is associated with peptic ulcer development

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Compromised NLRP 3 and AIM 2 inflammasome function in autoimmune NZB /W F1 mouse macrophages

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Herpesviruses and Inflammasomes: One Sensor Does Not Fit All

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Catenin' on to nucleic acid sensing

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Comparative analysis of absent in melanoma 2-inflammasome activation in Francisella tularensis and Francisella novicida

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Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection

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Microbial crosstalk along the oral–gut axis: organ-specific oncogenic adaptations of Porphyromonas gingivalis and Fusobacterium nucleatum

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The Comparative Effects of Schwann Cells and Wharton's Jelly Mesenchymal Stem Cells on the AIM2 Inflammasome Activity in an Experimental Model of Spinal Cord Injury

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Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases

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No Time to Die: How Cytomegaloviruses Suppress Apoptosis, Necroptosis, and Pyroptosis

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Innate Immunity

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Caspase-1 als Regulator der Autoinflammation bei rheumatischen Erkrankungen

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Protein interactions of the inflammasome adapter ASC by solution NMR

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Antiviral Response Induced by Toll-Like Receptor (TLR) 7/TLR8 Activation Inhibits Human Immunodeficiency Virus Type 1 Infection in Cord Blood Macrophages

Pietrobon, A. J., Yoshikawa, F. S. Y., de Oliveira, L. M., Pereira, N. Z., Matozo, T., de Alencar, B. C., Duarte, A. J. S., & Sato, M. N. (2021) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiab389 · Cited by 10

Inflammasome elements in epilepsy and seizures

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Recognition of Legionella pneumophila nucleic acids by innate immune receptors

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Ecology of Viruses Infecting Ectothermic Vertebrates—The Impact of Ranavirus Infections on Amphibians

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Cytomegalovirus Biology Viewed Through a Cell Death Suppression Lens

Mocarski, E. S. (2024) · Viruses · doi:10.3390/v16121820 · Cited by 9

Inflammasomes: potential therapeutic targets in hematopoietic stem cell transplantation

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Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity

Malik, H. S., & Bliska, J. B. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1012884 · Cited by 11

Role of inflammasomes in diabetes mellitus: mechanisms, complications, and therapeutic potential

Milan, K. L., Megha, B., & Ramkumar, K. M. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10719-5 · Cited by 9

Metal-doping engineering-driven STING-PANoptosis cascade for enhanced cancer sono-immunotherapy

Lei, H., Li, X., Liu, L., Chen, Y., Sun, S., Lu, S., Lian, L., Hou, G., & Cheng, L. (2025) · Cell Biomaterials · doi:10.1016/j.celbio.2025.100196 · Cited by 9

PANoptosis: A novel therapeutic target in kidney disease (Review)

Jiang, L., Zhao, L., Liu, Y., Fu, Z., Wu, M., Mou, Z., & Li, M. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5648 · Cited by 9

Epigenome-wide association analyses of active injection drug use

Shu, C., Jaffe, A. E., Sabunciyan, S., Ji, H., Astemborski, J. A., Sun, J., Bakulski, K. M., Sosnowski, D. W., Mehta, S. H., Kirk, G. D., et al. (2022) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2022.109431 · Cited by 10

A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome

Song, J., Wu, J., Robichaux, D. J., Li, T., Wang, S., Sancristobal, M. J. A., Dong, B., Dobrev, D., Karch, J. M., Thomas, S. S., et al. (2024) · Cells · doi:10.3390/cells13020108 · Cited by 9

Novel Insights into the Interaction between Enteropathogenic Bacteria, Pyroptosis and IBD

Bao, Z., Deng, Y., Qian, Z., & Zhuang, Y. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2907254 · Cited by 9

Intracellular sensors of immunity and allogeneic hematopoietic stem cell transplantation

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Cell biology and immunology lessons taught by Legionella pneumophila

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L’inflammasome NLRP3 : physiopathologie et application thérapeutique

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C. sakazakii activates AIM2 pathway accompanying with excessive ER stress response in mammalian mammary gland epithelium

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SON DNA‐binding protein mediates macrophage autophagy and responses to intracellular infection

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Absent in melanoma 2 suppresses gastric cancer cell proliferation and migration via inactivation of AKT signaling pathway

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The Inflammasome as a Target of Modulation by DNA Viruses

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A Proteomics Perspective on Viral DNA Sensors in Host Defense and Viral Immune Evasion Mechanisms

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AIM2 Joins the Gang of Microbial Sensors

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Immune Activation in the Liver by Nucleic Acids

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