Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy

Phosphorylation meets ubiquitination: the control of NF-κB activity

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Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin

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DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

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Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I

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Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

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HIV Entry and Its Inhibition

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A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

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Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells

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HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

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Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

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Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

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Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

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The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

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Functional Regions of the Envelope Glycoprotein of Human Immunodeficiency Virus Type 1

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Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1

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HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap

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A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

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Evidence for Budding of Human Immunodeficiency Virus Type 1 Selectively from Glycolipid-Enriched Membrane Lipid Rafts

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Specific incorporation of cyclophilin A into HIV-1 virions

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Generic Signals and Specific Outcomes

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HIV-1 Gag proteins: diverse functions in the virus life cycle

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Plasma membrane rafts play a critical role in HIV-1 assembly and release

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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

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P-TEFb, a Cyclin-Dependent Kinase Controlling Elongation by RNA Polymerase II

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A Novel Human WD Protein, h-βTrCP, that Interacts with HIV-1 Vpu Connects CD4 to the ER Degradation Pathway through an F-Box Motif

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Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

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In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression

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Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

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CONTROL OF RNA INITIATION AND ELONGATION AT THE HIV-1 PROMOTER

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Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55 Gag

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Global distribution of the CCR5 gene 32-basepair deletion

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The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle

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DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection

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HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo

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HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

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The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation

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Flavopiridol Inhibits P-TEFb and Blocks HIV-1 Replication

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Nef Harbors a Major Determinant of Pathogenicity for an AIDS-like Disease Induced by HIV-1 in Transgenic Mice

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NF-κB Binds P-TEFb to Stimulate Transcriptional Elongation by RNA Polymerase II

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The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein

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HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence

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Nef Interacts with the μ Subunit of Clathrin Adaptor Complexes and Reveals a Cryptic Sorting Signal in MHC I Molecules

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Structure–function relationships in HIV‐1 Nef

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Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes.

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Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

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Lipid Rafts and HIV Pathogenesis: Host Membrane Cholesterol Is Required for Infection by HIV Type 1

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Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest

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Selective Transcription and Modulation of Resting T Cell Activity by Preintegrated HIV DNA

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Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

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HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

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HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

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A role for ubiquitin ligase recruitment in retrovirus release

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HIV-1 Nef associated PAK and PI3-Kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

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HIV-1 nef leads to inhibition or activation of T cells depending on its intracellular localization

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Establishment of a Functional Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcription Complex Involves the Cytoskeleton

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Lipid rafts and HIV-1: from viral entry to assembly of progeny virions

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Evidence for a newly discovered cellular anti-HIV-1 phenotype

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The Nef protein of HIV-1 associates with rafts and primes T cells for activation

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Dynamic Disruptions in Nuclear Envelope Architecture and Integrity Induced by HIV-1 Vpr

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Nef Triggers a Transcriptional Program in T Cells Imitating Single-Signal T Cell Activation and Inducing HIV Virulence Mediators

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The plasma membrane as a combat zone in the HIV battlefield

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Identification of a host protein essential for assembly of immature HIV-1 capsids

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Induction of Fas Ligand Expression by HIV Involves the Interaction of Nef with the T Cell Receptor ζ Chain

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Interactions between HIV1 Nef and Vacuolar ATPase Facilitate the Internalization of CD4

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CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor

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Cytoplasmic Recruitment of INI1 and PML on Incoming HIV Preintegration Complexes

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CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef

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The barrier-to-autointegration protein is a host factor for HIV type 1 integration

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Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts.

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Multiple Blocks to Human Immunodeficiency Virus Type 1 Replication in Rodent Cells

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Organization of Immature Human Immunodeficiency Virus Type 1

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A Block to Human Immunodeficiency Virus Type 1 Assembly in Murine Cells

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Nef increases infectivity of HIV via lipid rafts

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CDK9 Autophosphorylation Regulates High-Affinity Binding of the Human Immunodeficiency Virus Type 1 Tat–P-TEFb Complex to TAR RNA

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Characterization of HIV Replication Complexes Early after Cell-to-Cell Infection

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Human Immunodeficiency Virus Type 1 Nef Functions at the Level of Virus Entry by Enhancing Cytoplasmic Delivery of Virions

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Human Immunodeficiency Virus Type 1 Nef Binds to Tumor Suppressor p53 and Protects Cells against p53-Mediated Apoptosis

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Cellular protein modulates effects of human immunodeficiency virus type 1 Rev

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Endocytic entry of HIV-1

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Tat Transactivation: A Model for the Regulation of Eukaryotic Transcriptional Elongation

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Retroviruses as Model Systems for the Study of Nuclear RNA Export Pathways

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A novel nuclear export activity in HIV-1 matrix protein required for viral replication

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HIV-1 Vpr Enhances Viral Burden by Facilitating Infection of Tissue Macrophages but Not Nondividing CD4+ T Cells

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Nucleocytoplasmic Shuttling by Human Immunodeficiency Virus Type 1 Vpr

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CD4 Down-Modulation by Human Immunodeficiency Virus Type 1 Nef Correlates with the Efficiency of Viral Replication and with CD4 + T-Cell Depletion in Human Lymphoid Tissue Ex Vivo

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Identification of Three Major Phosphorylation Sites within HIV-1 Capsid

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Role of Vif in Stability of the Human Immunodeficiency Virus Type 1 Core

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HIV Rev-dependent binding of SF2/ASF to the Rev response element: Possible role in Rev-mediated inhibition of HIV RNA splicing

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