The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Reticulon family members modulate BACE1 activity and amyloid-β peptide generation
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., et al. (1999) · Science · doi:10.1126/science.286.5440.735 · Cited by 3,876
Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
Yang, L.-B., Lindholm, K., Yan, R., Citron, M., Xia, W., Yang, X.-L., Beach, T., Sue, L., Wong, P., Price, D., et al. (2003) · Nature Medicine · doi:10.1038/nm0103-3 · Cited by 729
Self-citationDifferentiation and death of premyelinating oligodendrocytes in developing rodent brain
Trapp, B. D., Nishiyama, A., Cheng, D., & Macklin, W. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.2.459 · Cited by 395
Cited by
APP processing in Alzheimer’s disease.
Zhang, Y.-W., Thompson, R., Zhang, H., & Xu, H. (2011) · Molecular Brain · doi:10.1186/1756-6606-4-3 · Cited by 983
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
Sun, X., He, G., Qing, H., Zhou, W., Dobie, F., Cai, F., Staufenbiel, M., Huang, L. E., & Song, W. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606298103 · Cited by 605
Bace1 modulates myelination in the central and peripheral nervous system
Hu, X., Hicks, C. W., He, W., Wong, P., Macklin, W. B., Trapp, B. D., & Yan, R. (2006) · Nature Neuroscience · doi:10.1038/nn1797 · Cited by 608
Self-citationVassar, R., Kovacs, D. M., Yan, R., & Wong, P. C. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3657-09.2009 · Cited by 577
Self-citationThe Alzheimer's disease Beta-secretase enzyme, BACE1
Cole, S. L., & Vassar, R. (2007) · Molecular Neurodegeneration · doi:10.1186/1750-1326-2-22 · Cited by 550
Activation of Necroptosis in Multiple Sclerosis
Ofengeim, D., Ito, Y., Najafov, A., Zhang, Y., Shan, B., DeWitt, J. P., Ye, J., Zhang, X., Chang, A., Vakifahmetoglu-Norberg, H., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.02.051 · Cited by 526
Self-citationBACE1 activity is modulated by cell-associated sphingosine-1-phosphate
Takasugi, N., Sasaki, T., Suzuki, K., Osawa, S., Isshiki, H., Hori, Y., Shimada, N., Higo, T., Yokoshima, S., Fukuyama, T., et al. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.6467-10.2011 · Cited by 181
BACE1 Deficiency Causes Altered Neuronal Activity and Neurodegeneration
Hu, X., Zhou, X., He, W., Yang, J., Xiong, W., Wong, P., Wilson, C. G., & Yan, R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1334-10.2010 · Cited by 162
Self-citationGenetic deletion of BACE1 in mice affects remyelination of sciatic nerves
Hu, X., He, W., Diaconu, C., Tang, X., Kidd, G. J., Macklin, W. B., Trapp, B. D., & Yan, R. (2008) · The FASEB Journal · doi:10.1096/fj.08-106666 · Cited by 155
Self-citationMatsuzaki, F., Shirane, M., Matsumoto, M., & Nakayama, K. I. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-01-0068 · Cited by 118
Ubiquitin Regulates GGA3-mediated Degradation of BACE1
Kang, E. L., Cameron, A. N., Piazza, F., Walker, K. R., & Tesco, G. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.092742 · Cited by 111
Sequential formation of different layers of dystrophic neurites in Alzheimer’s brains
Sharoar, M. G., Hu, X., Ma, X.-M., Zhu, X., & Yan, R. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0396-2 · Cited by 87
Self-citationThe Basic Biology of BACE1: A Key Therapeutic Target for Alzheimers Disease
Vassar, R., & Cole, S. (2007) · Current Genomics · doi:10.2174/138920207783769512 · Cited by 84
BACE1 Regulates Hippocampal Astrogenesis via the Jagged1-Notch Pathway
Hu, X., He, W., Luo, X., Tsubota, K. E., & Yan, R. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.06.005 · Cited by 81
Self-citationβ-Secretase: its biology as a therapeutic target in diseases
Wang, H., Li, R., & Shen, Y. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.01.008 · Cited by 69
Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing
Zhao, Y., Wang, Y., Yang, J., Wang, X., Zhao, Y., Zhang, X., & Zhang, Y.-W. (2012) · Molecular Neurodegeneration · doi:10.1186/1750-1326-7-30 · Cited by 63
Kang, E. L., Biscaro, B., Piazza, F., & Tesco, G. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.407072 · Cited by 55
BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer’s disease
Bao, J., Qin, M., Mahaman, Y. A. R., Zhang, B., Huang, F., Zeng, K., Xia, Y., Ke, D., Wang, Q., Liu, R., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800498115 · Cited by 50
Tang, F.-L., Zhao, L., Zhao, Y., Sun, D., Zhu, X.-J., Mei, L., & Xiong, W.-C. (2020) · Cell Death & Differentiation · doi:10.1038/s41418-019-0487-2 · Cited by 47
He, W., Hu, J., Xia, Y., & Yan, R. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.579862 · Cited by 41
Self-citationProtein-Protein Interactions and Aggregation Inhibitors in Alzheimer’s Disease
Ganeshpurkar, A., Swetha, R., Kumar, D., Gangaram, G. P., Singh, R., Gutti, G., Jana, S., Kumar, D., Kumar, A., & Singh, S. K. (2019) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026619666190304153353 · Cited by 30
Zhao, Y., Wang, Y., Hu, J., Zhang, X., & Zhang, Y.-W. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.330209 · Cited by 28
Post-translational regulation of the β-secretase BACE1
Araki, W. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.04.009 · Cited by 26
Development and characterization of a novel membrane assay for full-length BACE-1 at pH 6.0.
Saric, A., Brügge, L. Z., Müller-Pompalla, D., Rysiok, T., Ousson, S., Permanne, B., Quattropani, A., Busch, M., Beher, D., & Hussain, I. (2013) · SLAS Discovery · doi:10.1177/1087057112462237 · Cited by 4
Metadata
- Authors
- He, W., Lu, Y., Qahwash, I., Hu, X.-Y., Chang, A., & Yan, R.
- Venue
- Nature Medicine
- Published
- 2004-08-01
- Volume
- 10
- Issue
- 9
- Pages
- 959-965
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1983751614
- Cited by
- 257
- References
- 3
- FWCI
- 11.40
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
