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siRNA-directed inhibition of HIV-1 infection

Novina, Carl D., Murray, Michael F., Dykxhoorn, Derek M., Beresford, Paul J., Riess, Jonathan, Lee, Sang-Kyung, Collman, Ronald G., Lieberman, Judy, Shankar, Premlata, Sharp, Phillip A.·2002·Nature Medicine

DOI 10.1038/nm725

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Role for a bidentate ribonuclease in the initiation step of RNA interference
Bernstein, E., Caudy, A. A., Hammond, S. M., & Hannon, G. J. (2001) · Nature · doi:10.1038/35053110 · Cited by 4,892
A System for Stable Expression of Short Interfering RNAs in Mammalian Cells
Brummelkamp, T. R., Bernards, R., & Agami, R. (2002) · Science · doi:10.1126/science.1068999 · Cited by 4,291
HOW CELLS RESPOND TO INTERFERONS
Stark, G. R., Kerr, I. M., Williams, B. R. G., Silverman, R. H., & Schreiber, R. D. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.227 · Cited by 3,932
RNA interference is mediated by 21- and 22-nucleotide RNAs
Elbashir, S. M., Lendeckel, W., & Tuschl, T. (2001) · Genes & Development · doi:10.1101/gad.862301 · Cited by 3,310
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection
Liu, R., Paxton, W. A., Choe, S., Ceradini, D., Martin, S. R., Horuk, R., MacDonald, M. E., Stuhlmann, H., Koup, R. A., & Landau, N. R. (1996) · Cell · doi:10.1016/s0092-8674(00)80110-5 · Cited by 3,074
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
Hammond, S. M., Bernstein, E., Beach, D., & Hannon, G. J. (2000) · Nature · doi:10.1038/35005107 · Cited by 3,003
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
Samson, M., Libert, F., Doranz, B. J., Rucker, J., Liesnard, C., Farber, C.-M., Saragosti, S., Lapouméroulie, C., Cognaux, J., Forceille, C., et al. (1996) · Nature · doi:10.1038/382722a0 · Cited by 2,886
Self-citation
A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA
Hutvágner, G., McLachlan, J., Pasquinelli, A. E., Bálint, E., Tuschl, T., & Zamore, P. D. (2001) · Science · doi:10.1126/science.1062961 · Cited by 2,781
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
Klatzmann, D., Champagne, E., Chamaret, S., Gruest, J., Guetard, D., Hercend, T., Gluckman, J.-C., & Montagnier, L. (1984) · Nature · doi:10.1038/312767a0 · Cited by 2,436
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
Maddon, P. J., Dalgleish, A. G., McDougal, J. S., Clapham, P. R., Weiss, R. A., & Axel, R. (1986) · Cell · doi:10.1016/0092-8674(86)90590-8 · Cited by 2,002
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
Grishok, A., Pasquinelli, A. E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D. L., Fire, A., Ruvkun, G., & Mello, C. C. (2001) · Cell · doi:10.1016/s0092-8674(01)00431-7 · Cited by 1,908
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
Ketting, R. F., Fischer, S. E. J., Bernstein, E., Sijen, T., Hannon, G. J., & Plasterk, R. H. A. (2001) · Genes & Development · doi:10.1101/gad.927801 · Cited by 1,852
Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi
Hammond, S. M., Boettcher, S., Caudy, A. A., Kobayashi, R., & Hannon, G. J. (2001) · Science · doi:10.1126/science.1064023 · Cited by 1,580
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J., & Conklin, D. S. (2002) · Genes & Development · doi:10.1101/gad.981002 · Cited by 1,552
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
Elbashir, S. M. (2001) · The EMBO Journal · doi:10.1093/emboj/20.23.6877 · Cited by 1,449
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
Tabara, H., Sarkissian, M., Kelly, W. G., Fleenor, J., Grishok, A., Timmons, L., Fire, A., & Mello, C. C. (1999) · Cell · doi:10.1016/s0092-8674(00)81644-x · Cited by 1,282
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
Sui, G., Soohoo, C., Affar, E. B., Gay, F., Shi, Y., Forrester, W. C., & Shi, Y. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082117599 · Cited by 1,104
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
Yu, J.-Y., DeRuiter, S. L., & Turner, D. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092143499 · Cited by 1,039
Gene silencing as an adaptive defence against viruses
Waterhouse, P. M., Wang, M.-B., & Lough, T. (2001) · Nature · doi:10.1038/35081168 · Cited by 980
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
Lee, N. S., Dohjima, T., Bauer, G., Li, H., Li, M.-J., Ehsani, A., Salvaterra, P., & Rossi, J. (2002) · Nature Biotechnology · doi:10.1038/nbt0502-500 · Cited by 953
A Similarity Between Viral Defense and Gene Silencing in Plants
Ratcliff, F., Harrison, B. D., & Baulcombe, D. C. (1997) · Science · doi:10.1126/science.276.5318.1558 · Cited by 838
Effective expression of small interfering RNA in human cells
Paul, C. P., Good, P. D., Winer, I., & Engelke, D. R. (2002) · Nature Biotechnology · doi:10.1038/nbt0502-505 · Cited by 820
mut-7 of C. elegans, Required for Transposon Silencing and RNA Interference, Is a Homolog of Werner Syndrome Helicase and RNaseD
Ketting, R. F., Haverkamp, T. H. A., van Luenen, H. G. A. M., & Plasterk, R. H. A. (1999) · Cell · doi:10.1016/s0092-8674(00)81645-1 · Cited by 736
RNA interference—2001
Sharp, P. A. (2001) · Genes & Development · doi:10.1101/gad.880001 · Cited by 701
Self-citation
Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression
Kim, S. Y., Byrn, R., Groopman, J., & Baltimore, D. (1989) · Journal of Virology · doi:10.1128/jvi.63.9.3708-3713.1989 · Cited by 577
HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence
Malim, M. H., Tiley, L. S., McCarn, D. F., Rusche, J. R., Hauber, J., & Cullen, B. R. (1990) · Cell · doi:10.1016/0092-8674(90)90670-a · Cited by 430
Sequence-specific RNA binding by the HIV-1 Rev protein
Zapp, M. L., & Green, M. R. (1989) · Nature · doi:10.1038/342714a0 · Cited by 386
RNA interference: listening to the sound of silence.
Zamore, P. D. (2001) · Nature Structural Biology · doi:10.1038/nsb0901-746 · Cited by 372
Selective Transcription and Modulation of Resting T Cell Activity by Preintegrated HIV DNA
Wu, Y., & Marsh, J. W. (2001) · Science · doi:10.1126/science.1061548 · Cited by 343
Complete Nucleotide Sequences of Functional Clones of the AIDS Virus
RATNER, L., FISHER, A., JAGODZINSKI, L. L., MITSUYA, H., LIOU, R.-S., GALLO, R. C., & WONG-STAAL, F. (1987) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1987.3.57 · Cited by 341
Antisense RNA: Function and Fate of Duplex RNA in Cells of Higher Eukaryotes
Kumar, M., & Carmichael, G. G. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1415-1434.1998 · Cited by 320
Gene silencing using micro-RNA designed hairpins
McMANUS, M. T., PETERSEN, C. P., HAINES, B. B., CHEN, J., & SHARP, P. A. (2002) · RNA · doi:10.1017/s1355838202024032 · Cited by 310
Self-citation
Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses
Bitko, V., & Barik, S. (2001) · BMC Microbiology · doi:10.1186/1471-2180-1-34 · Cited by 287
Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection
Chackerian, B., Long, E. M., Luciw, P. A., & Overbaugh, J. (1997) · Journal of Virology · doi:10.1128/jvi.71.5.3932-3939.1997 · Cited by 267
Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68.
Jones, A. R., & Schedl, T. (1995) · Genes & Development · doi:10.1101/gad.9.12.1491 · Cited by 245
Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA
Cochrane, A. W., Chen, C. H., & Rosen, C. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.3.1198 · Cited by 165 · cited 1×
“The Rev protein of HIV-1 contains a nuclear-export signal and interacts with the rev responsive element in the env coding region, permitting transport of pre-spliced viral RNA to the cytoplas”
Control of developmental timing by small temporal RNAs: a paradigm for RNA‐mediated regulation of gene expression
Banerjee, D., & Slack, F. J. (2002) · BioEssays · doi:10.1002/bies.10046 · Cited by 165
Control of developmental timing in animals
Rougvie, A. E. (2001) · Nature Reviews Genetics · doi:10.1038/35088566 · Cited by 137
The Therapeutic Potential of Ribozymes
James, H. A., & Gıbson, I. (1998) · Blood · doi:10.1182/blood.v91.2.371 · Cited by 113
Cosuppression of Nonhomologous Transgenes in Drosophila Involves Mutually Related Endogenous Sequences
Pal‐Bhadra, M., Bhadra, U., & Birchler, J. A. (1999) · Cell · doi:10.1016/s0092-8674(00)80060-4 · Cited by 87
Viral-Specific Cytotoxic T Lymphocytes Lyse Human Immunodeficiency Virus–Infected Primary T Lymphocytes by the Granule Exocytosis Pathway
Shankar, P., Xu, Z., & Lieberman, J. (1999) · Blood · doi:10.1182/blood.v94.9.3084 · Cited by 75
Self-citation
Post-transcriptional regulation of sex determination in Caenorhabditis elegans: widespread expression of the sex-determining gene fem-1 in both sexes.
Gaudet, J., Vanderelst, I. E., & Spence, A. M. (1996) · Molecular Biology of the Cell · doi:10.1091/mbc.7.7.1107 · Cited by 54
RNA‐based gene therapy for HIV infection
Dorman, N., & Lever, A. M. L. (2001) · HIV Medicine · doi:10.1046/j.1468-1293.2001.00052.x · Cited by 10

Strategies for silencing human disease using RNA interference
Kim, D. H., & Rossi, J. J. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2006 · Cited by 1,078
RNAi therapeutics: Principles, prospects and challenges
Aagaard, L., & Rossi, J. J. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.03.005 · Cited by 895
Stable suppression of tumorigenicity by virus-mediated RNA interference
Brummelkamp, T. R., Bernards, R., & Agami, R. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00122-8 · Cited by 886
Tolerance for mutations and chemical modifications in a siRNA
Amarzguioui, M. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg147 · Cited by 534
Efficient Reduction of Target RNAs by Small Interfering RNA and RNase H-dependent Antisense Agents
Vickers, T. A., Koo, S., Bennett, C. F., Crooke, S. T., Dean, N. M., & Baker, B. F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210326200 · Cited by 461

See all 773

Authors: Novina, C. D., Murray, M. F., Dykxhoorn, D. M., Beresford, P. J., Riess, J., Lee, S.-K., Collman, R. G., Lieberman, J., Shankar, P., & Sharp, P. A.
Venue: Nature Medicine
Publisher: Springer Science and Business Media LLC
Published: 2002-06-03
Volume: 8
Issue: 7
Pages: 681-686
ISSN: 1078-8956 (ISSN-L)
1546-170X
DOI: 10.1038/nm725
OpenAlex: W2084851425
Cited by: 773
References: 43
FWCI: 33.05
Type: journal article
Language: en
Open access: closed

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siRNA-directed inhibition of HIV-1 infection

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