The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A reprogrammable mouse strain from gene-targeted embryonic stem cells
Open accessAbstract
The derivation of induced pluripotent stem cells (iPSCs) usually involves the viral introduction of reprogramming factors into somatic cells. Here we used gene targeting to generate a mouse strain with a single copy of an inducible, polycistronic reprogramming cassette, allowing for the induction of pluripotency in various somatic cell types. As these 'reprogrammable mice' can be easily bred, they are a useful tool to study the mechanisms underlying cellular reprogramming.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
Stadtfeld, M., Maherali, N., Breault, D. T., & Hochedlinger, K. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.02.001 · Cited by 823
Self-citationInduced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette
Sommer, C. A., Stadtfeld, M., Murphy, G. J., Hochedlinger, K., Kotton, D. N., & Mostoslavsky, G. (2009) · Stem Cells · doi:10.1634/stemcells.2008-1075 · Cited by 676
Self-citationA High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells
Maherali, N., Ahfeldt, T., Rigamonti, A., Utikal, J., Cowan, C., & Hochedlinger, K. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.08.003 · Cited by 563
Self-citation
Cited by
A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
Polo, J. M., Anderssen, E., Walsh, R. M., Schwarz, B. A., Nefzger, C. M., Lim, S. M., Borkent, M., Apostolou, E., Alaei, S., Cloutier, J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.11.039 · Cited by 861
Self-citationSchiebinger, G., Shu, J., Tabaka, M., Cleary, B., Subramanian, V., Solomon, A., Gould, J., Liu, S., Lin, S., Berube, P., et al. (2019) · Cell · doi:10.1016/j.cell.2019.01.006 · Cited by 829
Self-citationConversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
Efe, J. A., Hilcove, S., Kim, J., Zhou, H., Ouyang, K., Wang, G., Chen, J., & Ding, S. (2011) · Nature Cell Biology · doi:10.1038/ncb2164 · Cited by 623
Reprogramming in vivo produces teratomas and iPS cells with totipotency features
Abad, M., Mosteiro, L., Pantoja, C., Cañamero, M., Rayon, T., Ors, I., Graña, O., Megías, D., Domínguez, O., Martínez, D., et al. (2013) · Nature · doi:10.1038/nature12586 · Cited by 547
Ohnishi, K., Semi, K., Yamamoto, T., Shimizu, M., Tanaka, A., Mitsunaga, K., Okita, K., Osafune, K., Arioka, Y., Maeda, T., et al. (2014) · Cell · doi:10.1016/j.cell.2014.01.005 · Cited by 460
Somers, A., Jean, J.-C., Sommer, C. A., Omari, A., Ford, C. C., Mills, J. A., Ying, L., Sommer, A. G., Jean, J. M., Smith, B. W., et al. (2010) · Stem Cells · doi:10.1002/stem.495 · Cited by 423
Progress in understanding reprogramming to the induced pluripotent state
Plath, K., & Lowry, W. E. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2955 · Cited by 289
Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System
Buckley, S. M., Aranda-Orgilles, B., Strikoudis, A., Apostolou, E., Loizou, E., Moran-Crusio, K., Farnsworth, C. L., Koller, A. A., Dasgupta, R., Silva, J. C., et al. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.09.011 · Cited by 272
Self-citationStadtfeld, M., Apostolou, E., Ferrari, F., Choi, J., Walsh, R. M., Chen, T., Ooi, S. S. K., Kim, S. Y., Bestor, T. H., Shioda, T., et al. (2012) · Nature Genetics · doi:10.1038/ng.1110 · Cited by 238
Self-citationSridharan, R., Gonzales-Cope, M., Chronis, C., Bonora, G., McKee, R., Huang, C., Patel, S., Lopez, D., Mishra, N., Pellegrini, M., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2768 · Cited by 220
Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency
Hansson, J., Rafiee, M. R., Reiland, S., Polo, J. M., Gehring, J., Okawa, S., Huber, W., Hochedlinger, K., & Krijgsveld, J. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.10.014 · Cited by 229
Self-citationHistorical origins of transdifferentiation and reprogramming
Graf, T. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.11.012 · Cited by 194
David, L., & Polo, J. M. (2014) · Stem Cell Research · doi:10.1016/j.scr.2014.03.007 · Cited by 126
Wang, C., Rabadan Ros, R., Martinez-Redondo, P., Ma, Z., Shi, L., Xue, Y., Guillen-Guillen, I., Huang, L., Hishida, T., Liao, H.-K., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23353-z · Cited by 119
Drouin‐Ouellet, J., Lau, S., Brattås, P. L., Rylander Ottosson, D., Pircs, K., Grassi, D. A., Collins, L. M., Vuono, R., Andersson Sjöland, A., Westergren‐Thorsson, G., et al. (2017) · EMBO Molecular Medicine · doi:10.15252/emmm.201607471 · Cited by 110
All Roads Lead to Induced Pluripotent Stem Cells: The Technologies of iPSC Generation
Hu, K. (2014) · Stem Cells and Development · doi:10.1089/scd.2013.0620 · Cited by 105
Prediction of single-cell RNA expression profiles in live cells by Raman microscopy with Raman2RNA
Kobayashi-Kirschvink, K. J., Comiter, C. S., Gaddam, S., Joren, T., Grody, E. I., Ounadjela, J. R., Zhang, K., Ge, B., Kang, J. W., Xavier, R. J., et al. (2024) · Nature Biotechnology · doi:10.1038/s41587-023-02082-2 · Cited by 93
Mor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., Elinger, D., Viukov, S., Geula, S., Krupalnik, V., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.07.004 · Cited by 79
Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming
Schwarz, B. A., Cetinbas, M., Clement, K., Walsh, R. M., Cheloufi, S., Gu, H., Langkabel, J., Kamiya, A., Schorle, H., Meissner, A., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.06.013 · Cited by 72
Self-citationAAV vector-mediated in vivo reprogramming into pluripotency
Senís, E., Mosteiro, L., Wilkening, S., Wiedtke, E., Nowrouzi, A., Afzal, S., Fronza, R., Landerer, H., Abad, M., Niopek, D., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05059-x · Cited by 64
TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
Seruggia, D., Oti, M., Tripathi, P., Canver, M. C., LeBlanc, L., Di Giammartino, D. C., Bullen, M. J., Nefzger, C. M., Sun, Y. B. Y., Farouni, R., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.03.025 · Cited by 51
Paine, P. T., Rechsteiner, C., Morandini, F., Desdín-Micó, G., Mrabti, C., Parras, A., Haghani, A., Brooke, R., Horvath, S., Seluanov, A., et al. (2024) · Frontiers in Aging · doi:10.3389/fragi.2023.1323194 · Cited by 13
Metadata
- Authors
- Stadtfeld, M., Maherali, N., Borkent, M., & Hochedlinger, K.
- Venue
- Nature Methods
- Published
- 2009-12-13
- Volume
- 7
- Issue
- 1
- Pages
- 53-55
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2005063364
- Cited by
- 208
- References
- 3
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
