Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
Palop, Jorge J, Mucke, Lennart·2010·Nature Neuroscience
DOI 10.1038/nn.2583
Cited by (133)
Items 101–133 of 133
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- Recent Development of Bifunctional Small Molecules to Study Metal‐Amyloid‐<i>β</i> Species in Alzheimer′s DiseaseBraymer, Joseph J., DeToma, Alaina S., Choi, Jung-Suk, Ko, Kristin S., Lim, Mi Hee · 2011 · International Journal of Alzheimer’s Disease
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- Amyloid-beta peptide decreases expression and function of glutamate transporters in nervous system cellsTong, Huichun, Zhang, Xiuping, Meng, Xingjun, Xu, Pingyi, Zou, Xiaoming, Qu, Shaogang · 2017 · The International Journal of Biochemistry & Cell Biology
- Transgenic Expression of Intraneuronal Aβ
<sub>42</sub>
But Not Aβ
<sub>40</sub>
Leads to Cellular Aβ Lesions, Degeneration, and Functional Impairment without Typical Alzheimer's Disease PathologyAbramowski, Dorothee, Rabe, Sabine, Upadhaya, Ajeet Rijal, Reichwald, Julia, Danner, Simone, Staab, Dieter, Capetillo-Zarate, Estibaliz, Yamaguchi, Haruyasu, Saido, Takaomi C., Wiederhold, Karl-Heinz et al. · 2012 · The Journal of Neuroscience
- ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer’s disease mouse modelChan, Elizabeth S., Shetty, Mahesh Shivarama, Sajikumar, Sreedharan, Chen, Christopher, Soong, Tuck Wah, Wong, Boon-Seng · 2016 · Scientific Reports
- Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal ActivityMiyamoto, Takashi, Kim, Daniel, Knox, Joseph A., Johnson, Erik, Mucke, Lennart · 2016 · Journal of Biological Chemistry
- The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathwayNaguib, Sarah, Lopez-Lee, Chloe, Torres, Eileen Ruth, Lee, Se-In, Zhu, Jingjie, Zhu, Daphne, Ye, Pearly, Norman, Kendra, Zhao, Mingrui, Wong, Man Ying et al. · 2025 · Immunity
- Characterization of Orange Peel Extract and Its Potential Protective Effect against Aluminum Chloride-Induced Alzheimer’s DiseaseAbd El-Aziz, Nourhan Mohammad Abd, Shehata, Mohamed Gamal, Alsulami, Tawfiq, Badr, Ahmed Noah, Elbakatoshy, Marwa Ramadan, Ali, Hatem Salama, El-Sohaimy, Sobhy Ahmed · 2022 · Pharmaceuticals
- In vivo diffusion tensor imaging of amyloid‐β‐induced white matter damage in miceSun, Shu-Wei, Liang, Hsiao-Fang, Mei, Jennifer, Xu, Dan, Shi, Wei-Xing · 2013 · Journal of Alzheimer s Disease
- Tau‑targeting multifunctional nanocomposite based on tannic acid-metal for near-infrared fluorescence/magnetic resonance bimodal imaging-guided combinational therapy in Alzheimer's diseaseGu, Yutian, Zhang, Qin, Huang, Honglin, Ho, Kwun Hei Willis, Zhang, Yu, Yi, Changqing, Zheng, Yifan, Chang, Raymond Chuen Chung, Wang, Emma Shujun, Yang, Mo · 2024 · Theranostics
- The Effects of Amyloid and Tau on Functional Network Connectivity in Older PopulationsWales, Ryan Michael, Leung, Hoi-Chung · 2021 · Brain Connectivity
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- Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell deathLison, H., Happel, M.F.K., Schneider, F., Baldauf, K., Kerbstat, S., Seelbinder, B., Schneeberg, J., Zappe, M., Goldschmidt, J., Budinger, E. et al. · 2014 · Neurobiology of Disease
- <i>APOE3</i>
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<i>R136S</i>
mutation confers resilience against tau pathology via cGAS-STING-IFN inhibitionNaguib, Sarah, Lopez-Lee, Chloe, Torres, Eileen Ruth, Lee, Se-In, Zhu, Jingjie, Zhu, Daphne, Ye, Pearly, Norman, Kendra, Zhao, Mingrui, Wong, Man Ying et al. · 2024
- 3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer’s diseaseLomoio, Selene, Pandey, Ravi S., Rouleau, Nicolas, Menicacci, Beatrice, Kim, WonHee, Cantley, William L., Haydon, Philip G., Bennett, David A., Young-Pearse, Tracy L., Carter, Gregory W. et al. · 2023 · Molecular Psychiatry
- Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer’s disease pathologyChen, Lingxuan, Christenson Wick, Zoé, Vetere, Lauren M., Vaughan, Nick, Jurkowski, Albert, Galas, Angelina, Diego, Keziah S., Philipsberg, Paul A., Soler, Ivan, Feng, Yu et al. · 2023 · The Journal of Neuroscience
- Osteoblast-Derived Lipocalin-2 Regulated by miRNA-96-5p/Foxo1 Advances the Progression of Alzheimer’s DiseaseWu, Bo-Wen, Guo, Jin-Dong, Wu, Mi-Shan, Liu, Yu, Lu, Meng, Zhou, Yu-Hui, Han, Hong-Wei · 2020 · Epigenomics
- Altered functional connectivity of cortical networks in semantic variant primary progressive aphasiaPopal, Haroon, Quimby, Megan, Hochberg, Daisy, Dickerson, Bradford C., Collins, Jessica A. · 2020 · NeuroImage: Clinical
- Destruction of ERP responses to deviance in an auditory oddball paradigm in amyloid infusion mice with memory deficitsKim, Bowon, Shin, Jisu, Kim, YoungSoo, Choi, Jee Hyun · 2020 · PLOS ONE
- Aberrant synaptic PTEN in symptomatic Alzheimer's patients may link synaptic depression to network failureDíaz González, Marta, Buberman, Assaf, Morales, Miguel, Ferrer, Isidro, Knafo, Shira · 2021 · Frontiers in Synaptic Neuroscience
- Characterization and purification of β−secretase inhibitory peptides fraction from sea cucumber (Holothuria spinifera) enzymatic hydrolysatesRathnayake, Anuruddhika Udayangani, Abuine, Racheal, Palanisamy, Subramanian, Lee, Jung Kwon, Byun, Hee-Guk · 2021 · Process Biochemistry
- Characterization of β-secretase inhibitory extracts from sea cucumber (Stichopus japonicus) hydrolysis with their cellular level mechanism in SH-SY5Y cellsMa, Eui-Hyoun, Rathnayake, A. U., Lee, Jung Kwon, Lee, Sang-Min, Byun, Hee-Guk · 2021 · European Food Research and Technology
- Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse modelAraya, Paula, Niemeyer, Brian, Schade, Kyndal, Dunn, Lauren N., Waugh, Katherine, Busquet, Nicolas, Brindley, Connie, Brown, Chrisstopher, Winkler, Caitlin, Lyford, Hannah R. et al. · 2025 · iScience
- VU0810464, a selective GIRK channel activator, improves hippocampal-dependent synaptic plasticity and memory disrupted by amyloid-β oligomersMulero-Franco, Jaime, Jimenez-Herrera, Raquel, Contreras, Ana, Djebari, Souhail, Jiménez-Díaz, Lydia, Navarro-López, Juan D. · 2025 · Biomedicine & Pharmacotherapy