Cited by 706Psychedelics and Drug StudiesTreatment of Major DepressionReligion, Spirituality, and Psychology

The DOI matches its Crossref record; 86 of the 86 references it cites were found in a registry or an index.

The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future

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Carhart-Harris, Robin L, Goodwin, Guy M·2017·Neuropsychopharmacology

Abstract

Plant-based psychedelics, such as psilocybin, have an ancient history of medicinal use. After the first English language report on LSD in 1950, psychedelics enjoyed a short-lived relationship with psychology and psychiatry. Used most notably as aids to psychotherapy for the treatment of mood disorders and alcohol dependence, drugs such as LSD showed initial therapeutic promise before prohibitive legislature in the mid-1960s effectively ended all major psychedelic research programs. Since the early 1990s, there has been a steady revival of human psychedelic research: last year saw reports on the first modern brain imaging study with LSD and three separate clinical trials of psilocybin for depressive symptoms. In this circumspective piece, RLC-H and GMG share their opinions on the promises and pitfalls of renewed psychedelic research, with a focus on the development of psilocybin as a treatment for depression.

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Research works printed but not linked: 6

  1. Huxley A (1954) The Doors of Perception. On the author's sensations under the influence of the drug mescalin.. Chatto & Windus: London.
  2. Pahnke WN (1966). Drugs and mysticism. Int J Parapsychol 8: 295–315.
  3. Passie T (1996). Hanscarl leuner—pioneer of hallucinogen research and psycholytic therapy. Maps Newslett 7: 46–49.
  4. Stoll W (1947). Lysergsäure-diäthyl-amid, ein Phantastikum aus der Mutterkorngruppe. Schweiz Arch Neur 60: 1–2.
  5. Wasson RG (1957). Seeking the magic mushroom. LIFE Magazine 49: 100–102.
  6. Watts R, Day C, Krzanowski J, Nutt D, Carhart-Harris R (2017). Patients' accounts of increased 'connection' and 'acceptance' after psilocybin for treatment-resistant depression. J Hum Psychol (in press).

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Metadata

Authors
Carhart-Harris, R. L., & Goodwin, G. M.
Affiliations
  • Imperial College London (GB)
  • Oxford Health NHS Foundation Trust (GB)
Corresponding author
Carhart-Harris, Robin L
Venue
Neuropsychopharmacology
Published
2017-04-26
Volume
42
Issue
11
Pages
2105-2113
ISSN
  • 0893-133X (ISSN-L)
  • 1740-634X
OpenAlex
W2610144880
Cited by
706
References
86
Citations by year
2026: 107 · 2025: 129 · 2024: 96 · 2023: 81 · 2022: 76 · 2021: 59 · 2020: 75 · 2019: 30 · 2018: 38 · 2017: 12
FWCI
6.41
Type
journal article
Language
en
Open access
Locations
  • Neuropsychopharmacology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
  • Spiral (Imperial College London) (submittedVersion)
Funders
Strong
Topics
  • Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
  • Social Sciences › Health › Religion, Spirituality, and Psychology
Keywords
psychedelics, psilocybin, LSD, depression treatment, mood disorders, alcoholism, psychedelic drug regulation
MeSH terms
Animals, Mental Disorders, Hallucinogens, Humans, Psilocybin, History, 20th Century, History, 21st Century

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