Genome engineering using the CRISPR-Cas9 system

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Items 401–500 of 1,083

1. Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo
   Brittany A. Elliott, Hsiang‐Ting Ho, Srivathsan V. Ranganathan, Sweta Vangaveti, Olga Ilkayeva, Hala Abou Assi, Alex K. Choi, Paul F. Agris, Christopher L. Holley · 2019 · Nature Communications
2. Chitosan for gene delivery: Methods for improvement and applications
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3. Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice
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4. Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers
   Kyle L. Ellefsen, Jesse R. Holt, Alice C. Chang, Jamison L. Nourse, Janahan Arulmoli, Armen H. Mekhdjian, Hamid Abuwarda, Francesco Tombola, Lisa A. Flanagan, Alexander R. Dunn et al. · 2019 · Communications Biology
5. Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer
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6. Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
   Matthew G. Durrant, Alison Fanton, Josh Tycko, Michaela M. Hinks, Sita S. Chandrasekaran, Nicholas Thomas Perry, Julia M. Schaepe, Peter P. Du, Peter Lotfy, Michael Cory Bassik et al. · 2022 · Nature Biotechnology
7. Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation
   Christopher P. Lapointe, Rosslyn Grosely, Alex G. Johnson, Jinfan Wang, Israel S. Fernández, Joseph Daniel Puglisi · 2021 · Proceedings of the National Academy of Sciences
8. Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer
   Carter J. Barger, Connor Branick, Linda Chee, Adam R. Karpf · 2019 · Cancers
9. Rapid and Precise Engineering of theCaenorhabditis elegansGenome with Lethal Mutation Co-Conversion and Inactivation of NHEJ Repair
   Jordan D. Ward · 2014 · Genetics
10. Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis–emphysema
    Susan E. Stanley, Dustin L. Gable, Christa L. Wagner, Thomas M. Carlile, Vidya Sagar Hanumanthu, Joshua D. Podlevsky, Sara E. Khalil, Amy Elizabeth Dezern, María F. Rojas-Durán, Carolyn D. Applegate et al. · 2016 · Science Translational Medicine
11. Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin
    Benjamin Z. Stanton, H. Courtney Hodges, Joseph P. Calarco, Simon M. G. Braun, Wai Lim Ku, Cigall Kadoch, Keji Zhao, Gerald R. Crabtree · 2016 · Nature Genetics
12. A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
    Shawn Lu Wen Tan, Saakshi Chadha, Yansheng Liu, Evelina Gabašová, David Perera, Karim Ahmed, Stephanie Constantinou, Xavier Renaudin, Mi-Young Lee, Ruedi H. Aebersold et al. · 2017 · Cell
13. Modelling diabetic nephropathy in mice
    Kengo Azushima, Susan B. Gurley, Thomas M. Coffman · 2017 · Nature Reviews Nephrology
14. A chromosome folding intermediate at the condensin-to-cohesin transition during telophase
    Kristin Abramo, Anne-Laure Valton, Sergey V. Venev, Hakan Özadam, A. Nicole Fox, Job Dekker · 2019 · Nature Cell Biology
15. Regulation of the RNAPII Pool Is Integral to the DNA Damage Response
    Ana Tufegdžić Vidaković, Richard Mitter, Gavin P. Kelly, Michelle Neumann, Michelle T. Harreman, Marta Rodríguez‐Martínez, Anna E. Herlihy, Juston C. Weems, Stefan Boeing, Vesela Encheva et al. · 2020 · Cell
16. Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia
    Jae Seok Lim, Ramu Gopalappa, Se Hoon Kim, Suresh Ramakrishna, Minji Lee, Junho Kim, Junho Kim, Sang Min Park, Junehawk Lee, Jung‐Hwa Oh et al. · 2017 · The American Journal of Human Genetics
17. A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity
    Jennifer Yinuo Cao, Aunoy Poddar, Leslie Magtanong, Jennifer H. Lumb, Trevor R. Mileur, Michael A. Reid, Cole M. Dovey, Jin Wang, Jason W. Locasale, Everett M Stone et al. · 2019 · Cell Reports
18. Neutrophil-activating therapy for the treatment of cancer
    Ian L. Linde, Tyler R. Prestwood, Jingtao Qiu, Genay O.W. Pilarowski, Miles Hamilton Linde, Xiangyue Zhang, Lei Shen, Nathan Edward Reticker-Flynn, David Kung‐Chun Chiu, Lauren Y. Sheu et al. · 2023 · Cancer Cell
19. Reinvigorating natural product combinatorial biosynthesis with synthetic biology
    Eunji Kim, Bradley S Moore, Yeo Joon Yoon · 2015 · Nature Chemical Biology
20. Tailor‐made CRISPR/Cas system for highly efficient targeted gene replacement in the rice blast fungus
    Takayuki Arazoe, Kennosuke Miyoshi, Tohru Yamato, Tetsuo Ogawa, Shuichi Ohsato, Tsutomu Arie, Shigeru Kuwata · 2015 · Biotechnology and Bioengineering
21. Lipid transport by TMEM24 at ER–plasma membrane contacts regulates pulsatile insulin secretion
    Joshua A. Lees, Mirko Messa, Elizabeth Wen Sun, Heather Wheeler, Federico Tesio Torta, Markus Rene Wenk, Pietro V. De Camilli, Karin M. Reinisch · 2017 · Science
22. Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade
    Qian Zhang, Fansen Meng, Shasha Chen, Steven W. Plouffe, Shiying Wu, Shengduo Liu, Xinran Li, Ruyuan Zhou, Junxian Wang, Bin Zhao et al. · 2017 · Nature Cell Biology
23. Genetic evidence that β-arrestins are dispensable for the initiation of β 2 -adrenergic receptor signaling to ERK
    Morgan O’Hayre, Kelsie Eichel, Silvia Avino, Xuefeng Zhao, Dana J. Steffen, Xiaodong Feng, Kouki Kawakami, Junken Aoki, Karen S. Messer, Roger K. Sunahara et al. · 2017 · Science Signaling
24. PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1
    Xu Qian, Xinjian Li, Zhumei Shi, Yan Xia, Qingsong Cai, Daqian Xu, Lin Tan, Linyong Du, Yanhua Zheng, Dan Yang Zhao et al. · 2019 · Molecular Cell
25. The ASC-1 complex disassembles collided ribosomes
    Juszkiewicz, Szymon, Speldewinde, Shaun H., Wan, Li, Svejstrup, Jesper Q., Hegde, Ramanujan S. · 2020 · Molecular Cell
26. Simple and Rapid In Vivo Generation of Chromosomal Rearrangements using CRISPR/Cas9 Technology
    Rafael B. Blasco, Elif Karaca, Chiara Ambrogio, Taek-Chin Cheong, Emre Karayol, Valerio Giacomo Minero, Claudia Voena, Roberto Chiarle · 2014 · Cell Reports
27. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9
    Louis M. Luttrell, Jialu Wang, Bianca Plouffe, Jeffrey S. Smith, Lama Yamani, Suneet Kaur, Pierre‐Yves Jean‐Charles, Christophe Gauthier, Mi‐Hye Lee, Biswaranjan Pani et al. · 2018 · Science Signaling
28. Recapitulating the human segmentation clock with pluripotent stem cells
    Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K. Saito, Ayako Nagahashi, Megumi Nishio, Long Zhe Guo, Shiro Ikegawa, Satoko Sakurai et al. · 2020 · Nature
29. Challenges of CRISPR/Cas9 applications for long non-coding RNA genes
    Ashish Goyal, Ksenia Myacheva, Matthias Groß, Marcel Klingenberg, Berta Duran Arqué, Sven Diederichs · 2016 · Nucleic Acids Research
30. Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia
    Kerstin Knies, Shojiro Inano, Marı́a José Ramı́rez, Masamichi Ishiai, Jordi Surrallés, Minoru Takata, Detlev Schindler · 2017 · Journal of Clinical Investigation
31. Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation
    Kimberly C. Lin, Toshiro Moroishi, Zhipeng Meng, Han-Sol Jeong, Steven W. Plouffe, Yoshitaka Sekido, Jiahuai Han, Hyun Woo Park, Kun‐Liang Guan · 2017 · Nature Cell Biology
32. CRISPR-Cas9–based treatment of myocilin-associated glaucoma
    Ankur Jain, Gulab S Zode, Ramesh B. Kasetti, F. Ann Ran, Winston X. Yan, Tasneem Putliwala Sharma, Kevin Bugge, Charles C. Searby, John H. Fingert, Feng Zhang et al. · 2017 · Proceedings of the National Academy of Sciences
33. C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity
    Bhuvaneish Thangaraj Selvaraj, Matthew R. Livesey, Chen Zhao, Jenna M. Gregory, Owain T. James, Elaine M. Cleary, Amit K. Chouhan, Angus B. Gane, Emma Perkins, Owen Dando et al. · 2018 · Nature Communications
34. TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition
    Ramachandran, Anassuya, Vizán, Pedro, Das, Debipriya, Chakravarty, Probir, Vogt, Janis, Rogers, Katherine W, Müller, Patrick, Hinck, Andrew P, Sapkota, Gopal P, Hill, Caroline S · 2018 · eLife
35. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis
    Tobias Schwerd, Stephen R.F. Twigg, Dominik Aschenbrenner, Santiago Manrique, Kerry Ann Miller, Indira B. Taylor, Melania Capitani, Simon J. McGowan, Elizabeth A. Sweeney, Astrid P. Weber et al. · 2017 · The Journal of Experimental Medicine
36. Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis
    Archita Das, Dipankar Ash, Abdelrahman Y. Fouda, Sudhahar Varadarajan, Young-Mee Kim, Yali Hou, Farlyn Z. Hudson, Brian K. Stansfield, Ruth B. Caldwell, Malgorzata McMenamin et al. · 2022 · Nature Cell Biology
37. Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer
    Neel Shah, Ping Wang, John Wongvipat, Wouter R. Karthaus, Wassim M. Abida, Joshua Armenia, Shira Rockowitz, Yotam Drier, B Bernstein, Henry W. Long et al. · 2017 · eLife
38. Flaviviruses Exploit the Lipid Droplet Protein AUP1 to Trigger Lipophagy and Drive Virus Production
    Jing Shu Zhang, Yun Lan, Ming Yuan Li, Mart Matthias Lamers, Maxime Fusade-Boyer, Elizabeth J. Klemm, Christoph Thiele, Joseph Ashour, Sumana Sanyal · 2018 · Cell Host & Microbe
39. In vitro characterization of the human segmentation clock
    Margarete Díaz-Cuadros, Daniel E. Wagner, Christoph Budjan, Alexis Hubaud, Oscar A. Tarazona, Sophia Donelly, Arthur Michaut, Ziad Al Tanoury, Kumiko Yoshioka-Kobayashi, Yusuke Niino et al. · 2020 · Nature
40. PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1
    Sunnie M. Yoh, Monika Schneider, Janna Seifried, Stephen Soonthornvacharin, Rana Elias Akleh, Kevin C. Olivieri, Paul D. De Jesus, Chunhai Ruan, Elisa de Castro, Pedro A. Ruiz et al. · 2015 · Cell
41. CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos
    Yanjiao Shao, Yuting Guan, Liren Wang, Zhongwei Qiu, Meizhen Liu, Yuting Chen, Lijuan Wu, Yongmei Li, Xueyun Ma, Mingyao Liu et al. · 2014 · Nature Protocols
42. A facile, rapid and sensitive detection of MRSA using a CRISPR-mediated DNA FISH method, antibody-like dCas9/sgRNA complex
    Kyeonghye Guk, Joo Oak Keem, Seul Gee Hwang, Hye‐Ran Kim, Taejoon Kang, Eun‐Kyung Lim, Juyeon Jung · 2017 · Biosensors and Bioelectronics
43. CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes
    Zhongming Ma, Akiyuki Taruno, Makoto Ohmoto, Masafumi Jyotaki, Jason Chu-Shern Lim, Hiroaki Miyazaki, Naomi Niisato, Yoshinori Marunaka, Robert J. Lee, Henry B. Hoff et al. · 2018 · Neuron
44. RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
    Huzefa Dungrawala, Kamakoti P. Bhat, Rémy A. Le Meur, Walter Chazin, Xia Ding, Shyam K. Sharan, Sarah R. Wessel, Aditya A. Sathe, Runxiang Zhao, David Cortez · 2017 · Molecular Cell
45. Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease
    Soojin Kim, Yvette C. Wong, Fanding Gao, Dimitri Krainc · 2021 · Nature Communications
46. Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation
    Yinghui Li, Qi-Ling Zhou, Wenjie Sun, Prashant Chandrasekharan, Hui Shan Cheng, Zhe Ying, Manikandan Lakshmanan, Anandhkumar Raju, Daniel Geoffrey Tenen, Shi‐Yuan Cheng et al. · 2015 · Nature Cell Biology
47. Efficient oligo nucleotide mediated CRISPR-Cas9 gene editing in Aspergilli
    Christina Spuur Nødvig, Jakob Blæsbjerg Nielsen, Martin E. Kogle, Zofia Dorota Jarczynska, Jan T. Lehmbeck, Dorte K. Klitgaard, Uffe Hasbro Mortensen · 2018 · Fungal Genetics and Biology
48. A splice variant of human Bmal1 acts as a negative regulator of the molecular circadian clock
    Ji‐Won Lee, Eonyoung Park, Ga Hye Kim, Ilmin Kwon, Kyungjin Kim · 2018 · Experimental & Molecular Medicine
49. A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
    Alexandre Beautrait, Justine S. Paradis, Brandon Zimmerman, Jenna Giubilaro, Ljiljana Nikolajev, Sylvain Armando, Hiroyuki Kobayashi, Lama Yamani, Yoon Namkung, Franziska M. Heydenreich et al. · 2017 · Nature Communications
50. Multiplex gene regulation by CRISPR-ddCpf1
    Xiaochun Zhang, Jingman Wang, Qiuxiang Cheng, Xuan Zheng, Guoping Zhao, Jin Wang · 2017 · Cell Discovery
51. Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins
    Alexander P. Hynes, Geneviève M. Rousseau, Daniel Agudelo, Adeline Goulet, Béatrice Amigues, Jérémy Loehr, Dennis A. Romero, Christophe Fremaux, Philippe Horvath, Yannick Doyon et al. · 2018 · Nature Communications
52. Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
    Lillian J. Eichner, Sonja N. Brun, Sébastien Herzig, Nathan P. Young, Stephanie D. Curtis, David B. Shackelford, Maxim Nikolaievich Shokhirev, Mathias Leblanc, Liliana I. Vera, Amanda Hutchins et al. · 2018 · Cell Metabolism
53. The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis
    Fang Zheng, Jianing Chen, Xiaoqian Zhang, Zifeng Wang, Jiewen Chen, Xiaorong Lin, Hongyan Huang, Wenkui Fu, Jing Liang, Wei Wu et al. · 2021 · Nature Communications
54. Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss
    Bence György, Carl A. Nist-Lund, Bifeng Pan, Yukako Asai, K. Domenica Karavitaki, Benjamin P. Kleinstiver, Sara P. Garcia, Mikołaj Piotr Zaborowski, Paola Solanes, Sofia Spataro et al. · 2019 · Nature Medicine
55. HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
    Gongshi Bai, Chames Kermi, Henriette Stoy, Carl J. Schiltz, Julien Bacal, Angela M. Zaino, Matthew Kyle Hadden, Brandt F. Eichman, Massimo Lopes, Karlene A. Cimprich · 2020 · Molecular Cell
56. BNIP3L/NIX degradation leads to mitophagy deficiency in ischemic brains
    Xiaoli Wu, Yanrong Zheng, Mengru Liu, Yue Li, Shijia Ma, Weidong Tang, Wenping Yan, Ming Cao, Wanqing Zheng, Lei Jiang et al. · 2020 · Autophagy
57. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use
    Tae Wan Kim, Jinghua Piao, So Yeon Koo, Sonja Kriks, Sun Young Chung, Doron Betel, Nicholas D. Socci, Se Joon Choi, Susan E. Zabierowski, Brittany N. Dubose et al. · 2021 · Cell stem cell
58. Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program
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59. Strategies for nonviral nanoparticle‐based delivery of CRISPR/Cas9 therapeutics
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60. Highly Parallel Profiling of Cas9 Variant Specificity
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61. TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)
    Melody M. H. Li, Zerlina Lau, Pamela Cheung, Eduardo G. Aguilar, William M. Schneider, Leonia Bozzacco, Henrik Molina, Eugen C. Buehler, Akinori Takaoka, Charles M. Rice et al. · 2017 · PLoS Pathogens
62. YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation
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63. Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
    Dominika Kwaśna, S.A. Abdul Rehman, Jayaprakash Natarajan, Stephen P. Matthews, Ross Madden, Virginia De Cesare, Simone Weidlich, Satpal Virdee, Ivan Ahel, Ian Gibbs‐Seymour et al. · 2018 · Molecular Cell
64. Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases
    Julia Konovalova, Dmytro Gerasymchuk, Ilmari Parkkinen, Piotr Chmielarz, Andrii Domanskyi · 2019 · International Journal of Molecular Sciences
65. VDAC2 enables BAX to mediate apoptosis and limit tumor development
    Chin, Hui San, Li, Mark X., Tan, Iris K. L., Ninnis, Robert L., Reljic, Boris, Scicluna, Kristen, Dagley, Laura F., Sandow, Jarrod J., Kelly, Gemma L., Samson, Andre L. et al. · 2018 · Nature Communications
66. Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
    Bartsch, Kareen, Knittler, Katharina, Borowski, Christopher, Rudnik, Sönke, Damme, Markus, Aden, Konrad, Spehlmann, Martina E., Frey, Norbert, Saftig, Paul, Chalaris, Athena et al. · 2017 · Human Molecular Genetics
67. The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i‐AAA protease YME1L
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68. Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin
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69. CRISPRseek: A Bioconductor Package to Identify Target-Specific Guide RNAs for CRISPR-Cas9 Genome-Editing Systems
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70. A Simple and Universal System for Gene Manipulation in Aspergillus fumigatus: In Vitro -Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates
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71. Tumor-derived exosomes antagonize innate antiviral immunity
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72. Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases
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73. OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
    Zhengkui Zhang, Jinjin Du, Shuai Wang, Li Shao, Ke Jin, Fang Li, Bajin Wei, Wei Ding, Peifen Fu, Hans van Dam et al. · 2018 · Molecular Cell
74. An efficient auxin-inducible degron system with low basal degradation in human cells
    Shiqian Li, Xavier Prasanna, Veijo T. Salo, Ilpo Vattulainen, Elina Ikonen · 2019 · Nature Methods
75. The Parkinson’s disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway
    Carla F. Bento, Avraham Ashkenazi, María Jiménez-Sánchez, David Chaim Rubinsztein · 2016 · Nature Communications
76. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
    Bin Wang, Zuliang Jie, Donghyun Joo, Alban Ordureau, Pengda Liu, Wenjian Gan, Jianping Guo, Jinfang Zhang, Brian J. North, Xiangpeng Dai et al. · 2017 · Nature
77. The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages
    Lan H. Chu, Mohanalaxmi Indramohan, Rojo A. Ratsimandresy, Anu Gangopadhyay, Emily P. Morris, Denise M. Monack, Andrea Dorfleutner, Christian Stehlik · 2018 · Nature Communications
78. A metabolic function of FGFR3-TACC3 gene fusions in cancer
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79. CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer’s Disease
    Bence György, Camilla Lööv, Mikołaj Piotr Zaborowski, Shuko Takeda, Benjamin P. Kleinstiver, Caitlin Commins, Ksenia V. Kastanenka, Dakai Mu, Adrienn Volak, Vilmantas Giedraitis et al. · 2018 · Molecular Therapy — Nucleic Acids
80. Development of Light‐Activated CRISPR Using Guide RNAs with Photocleavable Protectors
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81. Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
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82. Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation
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83. Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors
    Wei Zhang, Si-Lu Yang, Mei Yang, Stephanie A. Herrlinger, Qiang Shao, John L. Collar, Edgar Fierro, Yanhong Shi, Aimin Liu, Hui Lü et al. · 2019 · Nature Communications
84. PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
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85. Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System
    Kankan Wang, Hongsheng Ouyang, Zicong Xie, Chaogang Yao, Nannan Guo, Mengjing Li, Huping Jiao, Daxin Pang · 2015 · Scientific Reports
86. Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations
    Ying Wai Chan, Kasper Fugger, Stephen Craig West · 2017 · Nature Cell Biology
87. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors
    John J. Seeley, Rebecca G. Baker, Mohamed Ghait, Tony Bruns, Matthew S. Hayden, Sachin D. Deshmukh, Daniel E. Freedberg, Sankar Ghosh · 2018 · Nature
88. Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
    Carol C. L. Chen, Shriya Deshmukh, Selin Jessa, Djihad Hadjadj, Véronique Lisi, Augusto Faria Andrade, Damien Faury, Wajih Jawhar, Rola Dali, Hiromichi Suzuki et al. · 2020 · Cell
89. C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling
    Joseph Amick, Agnes Roczniak-Ferguson, Shawn M. Ferguson · 2016 · Molecular Biology of the Cell
90. Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo
    Qi Liu, Kai Zhao, Chun Wang, Zhanzhan Zhang, Chunxiong Zheng, Yu Zhao, Yadan Zheng, Chaoyong Liu, Yingli An, Linqi Shi et al. · 2018 · Advanced Science
91. Regulation of the ER stress response by a mitochondrial microprotein
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92. Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers
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93. Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels
    Adrián Cárdenas, Ana Villalba, Camino de Juan Romero, Esther Picó, Christina Kyrousi, Athanasia C. Tzika, Marc Tessier‐Lavigne, Le Ma, Micha Drukker, Silvia Cappello et al. · 2018 · Cell
94. Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection
    Yihan Wan, Dimitrios G. Anastasakis, Joseph Rodriguez, Murali Palangat, Prabhakar R. Gudla, George Zaki, Mayank Tandon, Gianluca Pegoraro, Carson C. Chow, Markus Hafner et al. · 2021 · Cell
95. Genome-wide Survey of Ribosome Collision
    Peixun Han, Yuichi Shichino, Tilman Schneider‐Poetsch, Mari Mito, Satoshi Hashimoto, Tsuyoshi Udagawa, Kenji Kohno, Minoru Yoshida, Yuichiro Mishima, Toshifumi Inada et al. · 2020 · Cell Reports
96. Rational designs of in vivo CRISPR-Cas delivery systems
    Cong‐Fei Xu, Guojun Chen, Ying‐Li Luo, Yue Zhang, Gui Zhao, Zi-Dong Lu, Anna Czarna, Zhen Gu, Jun Wang · 2019 · Advanced Drug Delivery Reviews
97. Defining genome architecture at base-pair resolution
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98. A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9
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