Genome engineering using the CRISPR-Cas9 system

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1. WDFY4 is required for cross-presentation in response to viral and tumor antigens
   Derek J. Theisen, Jesse T. Davidson, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner et al. · 2018 · Science
2. The histone variant H2A.Z in gene regulation
   Benedetto Daniele Giaimo, Francesca Ferrante, Andreas Herchenröther, Sandra B. Hake, Tilman Borggrefe · 2019 · Epigenetics & Chromatin
3. Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells*
   Matthew C. Canver, Daniel E. Bauer, Abhishek Dass, Yvette Y. Yien, Jacky Chung, Takeshi Masuda, Takahiro Maeda, Barry H. Paw, Stuart H. Orkin · 2014 · Journal of Biological Chemistry
4. Generation of inner ear organoids containing functional hair cells from human pluripotent stem cells
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5. Conservation of biodiversity in the genomics era
   Megan A. Supple, Beth Shapiro · 2018 · Genome biology
6. Chemoconnectomics: Mapping Chemical Transmission in Drosophila
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7. Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination
   Szymon Juszkiewicz, Ramanujan S. Hegde · 2017 · Molecular Cell
8. Exosomes, a New Star for Targeted Delivery
   Huizhi Chen, Liyan Wang, Xinling Zeng, Herbert Schwarz, Himansu Sekhar Nanda, Xinsheng Peng, Yubin Zhou · 2021 · Frontiers in Cell and Developmental Biology
9. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma
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10. The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson's disease
    Schöndorf, David C., Ivanyuk, Dina, Baden, Pascale, Sanchez-Martinez, Alvaro, De Cicco, Silvia, Yu, Cong, Giunta, Ivana, Schwarz, Lukas K., Di Napoli, Gabriele, Panagiotakopoulou, Vasiliki et al. · 2018 · Cell Reports
11. p21 in Cancer Research
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12. LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance
    Cunha, Larissa D., Yang, Mao, Carter, Robert, Guy, Clifford, Harris, Lacie, Crawford, Jeremy C., Quarato, Giovanni, Boada-Romero, Emilio, Kalkavan, Halime, Johnson, Michael D.L. et al. · 2018 · Cell
13. Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites
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14. State-of-the-art design and rapid-mixing production techniques of lipid nanoparticles for nucleic acid delivery
    Evers, Martijn J. W., Kulkarni, Jayesh A., van der Meel, Roy, Cullis, Pieter R., Vader, Pieter, Schiffelers, Raymond M. · 2018 · Small Methods
15. Hepatitis C Virus RNA Functionally Sequesters miR-122
    Joseph M. Luna, Troels K. H. Scheel, Tal Danino, Katharina S. Shaw, Aldo Mele, John J. Fak, Eiko Nishiuchi, Constantin N. Takacs, Maria Teresa Catanese, Ype P. de Jong et al. · 2015 · Cell
16. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
    Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Benjamin Schendzielorz, Laura Melchionda et al. · 2021 · Cell Metabolism
17. Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
    Michal Harel, Rona Ortenberg, Siva Karthik Varanasi, Kailash Chandra Mangalhara, Mariya Mardamshina, Ettai Markovits, Erez N. Baruch, Victoria Tripple, May Arama-Chayoth, Eyal Greenberg et al. · 2019 · Cell
18. CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
    Kim, Jiyeon, Hu, Zeping, Cai, Ling, Li, Kailong, Choi, Eunhee, Faubert, Brandon, Bezwada, Divya, Rodriguez-Canales, Jaime, Villalobos, Pamela, Lin, Yu-Fen et al. · 2017 · Nature
19. CRISPR-Cas9 system: A new-fangled dawn in gene editing
    Darshana Gupta, Oindrila Bhattacharjee, Drishti Mandal, Madhab Kumar Sen, Dhritiman Dey, Adhiraj Dasgupta, Tawsif Ahmed Kazi, Rahul Kumar Gupta, Senjuti Sinharoy, Krishnendu Acharya et al. · 2019 · Life Sciences
20. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane
    O'Neill, Katelyn L., Huang, Kai, Zhang, Jingjing, Chen, Yi, Luo, Xu · 2016 · Genes & Development
21. H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
    Cai, Yichao, Zhang, Ying, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Cao, Zhendong, Raju, Anandhkumar, Lieberman Aiden, Erez, Li, Shang, Manikandan, Lakshmanan et al. · 2021 · Nature Communications
22. MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death
    Isabel Jaco, Alessandro Annibaldi, Najoua Lalaoui, Rebecca Wilson, Tencho Tenev, Lucie Laurien, CHUN SUNG KIM, Kunzah Jamal, Sidonie Wicky John, Gianmaria Liccardi et al. · 2017 · Molecular Cell
23. CRISPR Ethics: Moral Considerations for Applications of a Powerful Tool
    Brokowski, Carolyn, Adli, Mazhar · 2019 · Journal of Molecular Biology
24. CRISPR/Cas9 genome editing in human hematopoietic stem cells.
    Bak, Rasmus O, Dever, Daniel P, Porteus, Matthew H · 2018 · Nature Protocols
25. CDK12 regulates DNA repair genes by suppressing intronic polyadenylation
    Dubbury, Sara J., Boutz, Paul L., Sharp, Phillip A. · 2018 · Nature
26. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity
    Philipp Hammerschmidt, Daniela Ostkotte, Hendrik Nolte, Mathias J. Gerl, Alexander Jaïs, Hanna L. Brunner, Hans‐Georg Sprenger, Motoharu Awazawa, Hayley T. Nicholls, Sarah M. Turpin-Nolan et al. · 2019 · Cell
27. Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling
    Jason Z. Zhang, Tsan‐Wen Lu, Lucas Martins Stolerman, Brian Tenner, Jin-fan Zhang, Jin-Fan Zhang, Martin Falcke, Padmini Rangamani, Susan Serota Taylor, Sohum Mehta et al. · 2020 · Cell
28. Rolling Circular Amplification (RCA)-Assisted CRISPR/Cas9 Cleavage (RACE) for Highly Specific Detection of Multiple Extracellular Vesicle MicroRNAs
    Ruixuan Wang, Xianxian Zhao, Xiaohui Chen, Xiaopei Qiu, Guangchao Qing, Hong Zhang, Liangliang Zhang, Xiaolin Hu, Zhuoqi He, Daidi Zhong et al. · 2019 · Analytical Chemistry
29. Cancer exosomes induce tumor innervation
    Marianna Madeo, Paul L. Colbert, Daniel W. Vermeer, Christopher T. Lucido, Jacob T. Cain, Elisabeth Good Vichaya, Aaron J. Grossberg, DesiRae Muirhead, Alex P. Rickel, Zhongkui Hong et al. · 2018 · Nature Communications
30. Stress- and ubiquitylation-dependent phase separation of the proteasome
    Sayaka Yasuda, Hikaru Tsuchiya, Ai Kaiho, Qiang Guo, Ken Ikeuchi, Akinori Endo, Naoko Arai, Fumiaki Ohtake, Shigeo Murata, Toshifumi Inada et al. · 2020 · Nature
31. CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo
    Alex Mas, Shauna Ebanks, Megan S. Keiser, Beverly L. Davidson · 2017 · Molecular Therapy
32. CRISPR/Cas9‐mediated targeted mutagenesis of GmFT2a delays flowering time in soya bean
    Yupeng Cai, Li Chen, Xiujie Liu, Chen Guo, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han, Wensheng Hou · 2017 · Plant Biotechnology Journal
33. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1
    Yamano, Takashi, Zetsche, Bernd, Ishitani, Ryuichiro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu · 2017 · Molecular Cell
34. ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy
    Qingzhou Chen, Ya Xiao, Peiyuan Chai, Pengli Zheng, Junlin Teng, Jianguo Chen · 2019 · Current Biology
35. A Mouse Geneticist’s Practical Guide to CRISPR Applications
    Priti Singh, John C. Schimenti, Ewelina Bolcun‐Filas · 2014 · Genetics
36. Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia
    Viktor Lukacs, Jayanti Mathur, Rong Mao, Pınar Bayrak‐Toydemir, Melinda Procter, Stuart M. Cahalan, Helen J. Kim, Michael Bandell, Nicola Longo, Ronald W. Day et al. · 2015 · Nature Communications
37. Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity
    Josh Tycko, Vic E. Myer, Patrick D. Hsu · 2016 · Molecular Cell
38. Caspase‐3 regulates the migration, invasion and metastasis of colon cancer cells
    Min Zhou, Xinjian Liu, Zonghai Li, Qian Huang, Fang Li, Chuan‐Yuan Li · 2018 · International Journal of Cancer
39. A non-canonical tricarboxylic acid cycle underlies cellular identity
    Arnold, Paige K., Jackson, Benjamin T., Paras, Katrina I., Brunner, Julia S., Hart, Madeleine L., Newsom, Oliver J., Alibeckoff, Sydney P., Endress, Jennifer, Drill, Esther, Sullivan, Lucas B. et al. · 2022 · Nature
40. Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases
    Jean-Baptiste Renaud, Charlotte Boix, Marine Charpentier, Anne De Cian, Julien Cochennec, Evelyne Duvernois‐Berthet, Loı̈c Perrouault, Laurent Tesson, Joanne Edouard, Reynald Thinard et al. · 2016 · Cell Reports
41. Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing
    Benedetta Artegiani, Delilah F. G. Hendriks, Joep Beumer, Rutger N.U. Kok, Xuan Zheng, Indi P. Joore, Susana M. Chuva de Sousa Lopes, Jeroen Sebastiaan van Zon, Sander J. Tans, Hans C. Clevers · 2020 · Nature Cell Biology
42. Exploiting SNP s for biallelic CRISPR mutations in the outcrossing woody perennial Populus reveals 4‐coumarate:CoA ligase specificity and redundancy
    Xiaohong Zhou, Thomas B. Jacobs, Liang‐Jiao Xue, Scott A. Harding, Chung‐Jui Tsai · 2015 · New Phytologist
43. Post-translational Regulation of Cas9 during G1 Enhances Homology-Directed Repair
    Tony Gutschner, Monika Hämmerle, Giannicola Genovese, Giulio Francesco Draetta, Lynda Chin · 2016 · Cell Reports
44. The ER membrane protein complex is a transmembrane domain insertase
    Alina Guna, Norbert Volkmar, John C. Christianson, Ramanujan S. Hegde · 2017 · Science
45. N-terminal degradation activates the NLRP1B inflammasome
    Ashley J. Chui, Marian C. Okondo, Sahana D. Rao, Kuo Gai, Andrew R. Griswold, Darren C. Johnson, Daniel P. Ball, Cornelius Y. Taabazuing, Elizabeth L. Orth-He, Brooke A. Vittimberga et al. · 2019 · Science
46. TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress
    Heeseon An, Alban Ordureau, João A. Paulo, Christopher J. Shoemaker, Vladimir Denic, J. Wade Harper · 2019 · Molecular Cell
47. Recent Advances in CRISPR/Cas9 Delivery Strategies
    Yip, Bon · 2020 · Biomolecules
48. Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice
    Tomomi Aida, Keiho Chiyo, Takako Usami, Harumi Ishikubo, Risa Imahashi, Yusaku Wada, Kenji F. Tanaka, Tetsushi Sakuma, Takashi Yamamoto, Kohichi Tanaka · 2015 · Genome biology
49. Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas
    Andrew A. Horwitz, Jessica M. Walter, Max G. Schubert, Stephanie H. Kung, Kristy M. Hawkins, Darren Platt, Aaron D. Hernday, Tina Mahatdejkul-Meadows, Wayne Szeto, Sunil S. Chandran et al. · 2015 · Cell Systems
50. CD44 regulates epigenetic plasticity by mediating iron endocytosis
    Sebastian Müller, Fabien Sindikubwabo, Tatiana Cañeque, Anne Lafon, Antoine Versini, Bérangère Lombard, Damarys Loew, Ting‐Di Wu, Christophe Ginestier, Emmanuelle Charafe‐Jauffret et al. · 2020 · Nature Chemistry
51. Targeting Hepatitis B Virus With CRISPR/Cas9
    Seeger, Christoph, Sohn, Ji A · 2014 · Molecular Therapy - Nucleic Acids
52. Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles
    Jason E. Lee, Peter I. Cathey, Haoxi Wu, Roy Parker, Gia K. Voeltz · 2020 · Science
53. F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer
    Jie Hong, Fangfang Guo, Shiyuan Lu, Chaoqin Shen, Dan Ma, Xinyu Zhang, Yile Xie, Tingting Yan, TaChung Yu, Tiantian Sun et al. · 2020 · Gut
54. A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis
    Dan Zhang, Yutong Liu, Yezhang Zhu, Qian Yun Zhang, Hongxing Guan, Shengduo Liu, Shasha Chen, Mei Chen, Chen Chen, Zhiyong Liao et al. · 2022 · Nature Cell Biology
55. The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction
    Fan Jiang, Kunlun Yin, Kun K. Wu, Mingmin Zhang, Shi‐Qiang Wang, Heping Cheng, Zhou Zhou, Bailong Xiao · 2021 · Nature Communications
56. High efficient multisites genome editing in allotetraploid cotton (Gossypium hirsutum) using CRISPR/Cas9 system
    Pengcheng Wang, Jun Zhang, Lin Sun, Yizan Ma, Jiao Xu, Sijia Liang, Jinwu Deng, Jiafu Tan, Qinghua Zhang, Lili Tu et al. · 2017 · Plant Biotechnology Journal
57. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
    Mark Y. Fang, Sebastian Markmiller, Anthony Q. Vu, Ashkan Javaherian, William E. Dowdle, Philippe Jolivet, Paul Bushway, Nicholas A. Castello, Ashmita Baral, Michelle Y. Chan et al. · 2019 · Neuron
58. Chiral carbon dots: synthesis, optical properties, and emerging applications
    Aaron Döring, Elena V. Ushakova, Andrey L. Rogach · 2022 · Light Science & Applications
59. Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
    Sydney X. Lu, Emma De Neef, James D. Thomas, Erich Y. Sabio, Benoı̂t Rousseau, Mathieu Gigoux, David A. Knorr, Benjamin D. Greenbaum, Yuval Elhanati, Simon J. Hogg et al. · 2021 · Cell
60. Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells
    Sandhu, Jaspreet, Li, Shiqian, Fairall, Louise, Pfisterer, Simon G., Gurnett, Jennifer E., Xiao, Xu, Weston, Thomas A., Vashi, Dipti, Ferrari, Alessandra, Orozco, Jose L. et al. · 2018 · Cell
61. Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses
    Li, Yize, Banerjee, Shuvojit, Wang, Yuyan, Goldstein, Stephen A., Dong, Beihua, Gaughan, Christina, Silverman, Robert H., Weiss, Susan R. · 2016 · Proceedings of the National Academy of Sciences
62. The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
    Dong Fang, Haiyun Gan, Jeong‐Heon Lee, Jing Han, Zhiquan Wang, Scott M. Riester, Long Guo Jin, Jianji Chen, Hui Zhou, Jinglong Wang et al. · 2016 · Science
63. Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
    Irene Miguel-Escalada, Sílvia Bonàs‐Guarch, Inês Cebola, Joan Ponsa-Cobas, Julen Mendieta-Esteban, Goutham Atla, Biola M. Javierre, Delphine Rolando, Irene Farabella, Claire C. Morgan et al. · 2019 · Nature Genetics
64. Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer
    Jingbo Li, Jiao Liu, Zhuan Zhou, Runliu Wu, Xin Chen, Chunhua Yu, Brent R. Stockwell, Guido Kroemer, Rui Kang, Daolin Tang · 2023 · Science Translational Medicine
65. MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control
    Tim König, Hendrik Nolte, Mari J. Aaltonen, Takashi Tatsuta, Michiel Krols, Thomas Stroh, Thomas Langer, Heidi May McBride · 2021 · Nature Cell Biology
66. Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury
    Ge Tao, Peter C. Kahr, Yuka Morikawa, Min Zhang, Mahdis Rahmani, Todd R. Heallen, Lele Li, Zhao Qing Sun, Eric N. Olson, Brad A. Amendt et al. · 2016 · Nature
67. Mitochondrial translation requires folate-dependent tRNA methylation
    Raphael J. Morscher, Gregory S. Ducker, Hsin‐Jung Li, Johannes Mayer, Zemer Gitai, Wolfgang Sperl, Joshua D. Rabinowitz · 2018 · Nature
68. Genetic identification of leptin neural circuits in energy and glucose homeostases
    Jie Xu, Christopher L. Bartolome, Cho Low, Xinchi Yi, Cheng-Hao Chien, Peng Wang, Dong Kong · 2018 · Nature
69. Mouse and human urothelial cancer organoids: A tool for bladder cancer research
    Jasper Mullenders, Evelien de Jongh, Anneta Brousali, Mieke M Roosen, Jan P. A. Blom, Harry Begthel, Jeroen Korving, Trudy G. N. Jonges, Onno Kranenburg, Richard Paul Meijer et al. · 2019 · Proceedings of the National Academy of Sciences
70. PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures
    Daniel Gleditzsch, Patrick Pausch, Hanna Müller-Esparza, Ahsen Özcan, Xiaohan Guo, Gert Bange, Lennart Randau · 2018 · RNA Biology
71. Integrated stress response of vertebrates is regulated by four eIF2α kinases
    Shusuke Taniuchi, Masato Miyake, Kazue Tsugawa, Miho Oyadomari, Seiichi Oyadomari · 2016 · Scientific Reports
72. Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
    Jakob Mejlvang, Hallvard Lauritz Olsvik, Steingrim Svenning, Jack‐Ansgar Bruun, Yakubu Princely Abudu, Kenneth Bowitz Larsen, Andreas Brech, Tom E. Hansen, Hanne Britt Brenne, Terkel Hansen et al. · 2018 · The Journal of Cell Biology
73. Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa
    Mrinal K. Sarkar, Grace A. Hile, Lam C. Tsoi, Xianying Xing, Jianhua J. Liu, Yun Liang, Céline C. Berthier, William R. Swindell, Matthew T. Patrick, Shuai Shao et al. · 2018 · Annals of the Rheumatic Diseases
74. Mining for Micropeptides
    Catherine A. Makarewich, Eric N. Olson · 2017 · Trends in Cell Biology
75. Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF
    Hansen, Anders S., Hsieh, Tsung-Han S., Cattoglio, Claudia, Pustova, Iryna, Saldaña-Meyer, Ricardo, Reinberg, Danny, Darzacq, Xavier, Tjian, Robert · 2019 · Molecular Cell
76. CRISPR-Cas based virus detection: Recent advances and perspectives
    Lijuan Yin, Shuli Man, Shengying Ye, Guozhen Liu, Long Ma · 2021 · Biosensors and Bioelectronics
77. Targeting of Photoreceptor Genes inChlamydomonas reinhardtiivia Zinc-Finger Nucleases and CRISPR/Cas9
    André Greiner, Simon Kelterborn, Heide Evers, Georg Kreimer, Irina A. Sizova, Peter Hegemann · 2017 · The Plant Cell
78. Identification of a cellularly active SIRT6 allosteric activator
    Zhimin Huang, Junxing Zhao, Wei Deng, Ying‐Yi Chen, Jialin Shang, Kun Song, Lu Zhang, Chengxiang Wang, Shaoyong Lu, Xiuyan Yang et al. · 2018 · Nature Chemical Biology
79. HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity
    Shiying Wu, Qian Zhang, Fei Zhang, Fansen Meng, Shengduo Liu, Ruyuan Zhou, Qingzhe Wu, Xinran Li, Li Shen, Jun Huang et al. · 2019 · Nature Cell Biology
80. An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design
    Yongping Zhao, Congsheng Zhang, Wénwén Liú, Wei Gao, Changlin Liu, Gaoyuan Song, Wenxue Li, Long Mao, Beijiu Chen, Yunbi Xu et al. · 2016 · Scientific Reports
81. ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications
    Layla Kawarada, Takeo Suzuki, Takayuki Ohira, Shoji Hirata, Kenjyo Miyauchi, Tsutomu Suzuki · 2017 · Nucleic Acids Research
82. Viral Delivery Systems for CRISPR
    Xu, Christine L., Ruan, Merry Z. C., Mahajan, Vinit B., Tsang, Stephen H. · 2019 · Viruses
83. An early cell shape transition drives evolutionary expansion of the human forebrain
    Silvia K. Benito-Kwiecinski, Stefano L. Giandomenico, Magdalena A. Sutcliffe, Erlend S. Riis, Paula Freire-Pritchett, Iva Kelava, Stephanie Wunderlich, Ulrich Martin, Gregory A. Wray, Katie McDole et al. · 2021 · Cell
84. CRISPR/Cas9-Mediated Genome Editing in Soybean Hairy Roots
    Yupeng Cai, Li Chen, Xiujie Liu, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han, Wensheng Hou · 2015 · PLoS ONE
85. A pluripotent stem cell-based model for post-implantation human amniotic sac development
    Yue Shao, Kenichiro Taniguchi, Ryan F. Townshend, Toshio Miki, Deborah L. Gumucio, Jianping Fu · 2017 · Nature Communications
86. A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma
    Xiaoyue Chen, Minjie Zhang, Haiyun Gan, Heping Wang, Jeong‐Heon Lee, Dong Fang, Gaspar J. Kitange, Lihong He, Zeng Hu, Ian F. Parney et al. · 2018 · Nature Communications
87. Structural mechanism of cGAS inhibition by the nucleosome
    Pathare, Ganesh R., Decout, Alexiane, Glück, Selene, Cavadini, Simone, Makasheva, Kristina, Hovius, Ruud, Kempf, Georg, Weiss, Joscha, Kozicka, Zuzanna, Guey, Baptiste et al. · 2020 · Nature
88. Structural basis for mismatch surveillance by CRISPR–Cas9
    Jack P. K. Bravo, Mu‐Sen Liu, Grace N. Hibshman, Tyler L. Dangerfield, Kyungseok Jung, Ryan S. McCool, Kenneth Allen Johnson, David Ward Taylor · 2022 · Nature
89. Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice
    Yu, Wenhan, Mookherjee, Suddhasil, Chaitankar, Vijender, Hiriyanna, Suja, Kim, Jung-Woong, Brooks, Matthew, Ataeijannati, Yasaman, Sun, Xun, Dong, Lijin, Li, Tiansen et al. · 2017 · Nature Communications
90. Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport
    Hashidate-Yoshida, Tomomi, Harayama, Takeshi, Hishikawa, Daisuke, Morimoto, Ryo, Hamano, Fumie, Tokuoka, Suzumi M, Eto, Miki, Tamura-Nakano, Miwa, Yanobu-Takanashi, Rieko, Mukumoto, Yoshiko et al. · 2015 · eLife
91. DNA synthesis technologies to close the gene writing gap
    Alex Hoose, Richard Vellacott, Marko Storch, Paul S. Freemont, Maxim G. Ryadnov · 2023 · Nature Reviews Chemistry
92. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment
    Jin Yang, Konstantinos Savvatis, Jong Seok Kang, Peidong Fan, Hongyan Zhong, Karen Schwartz, Vivian Barry, Amanda J. Mikels, Serge Karpinski, Dmytro Kornyeyev et al. · 2016 · Nature Communications
93. Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
    Abigail S. Krall, Peter J. Mullen, Felicia Surjono, Milica Momcilovic, Ernst W. Schmid, Christopher J. Halbrook, Apisadaporn Thambundit, Steven D. Mittelman, Costas Andreas Lyssiotis, David B. Shackelford et al. · 2021 · Cell Metabolism
94. Highly efficient CRISPR mutagenesis by microhomology-mediated end joining in Aspergillus fumigatus
    Chi Zhang, Xiuhua Meng, Xiaolei Wei, Ling Lü · 2015 · Fungal Genetics and Biology
95. Locally translated mTOR controls axonal local translation in nerve injury
    Marco Terenzio, Sandip Koley, Nitzan Samra, Ida Rishal, Qian Cheng Zhao, Pabitra Kumar Sahoo, Anatoly Urisman, Letizia Marvaldi, Juan A. Osés-Prieto, Craig M. Forester et al. · 2018 · Science
96. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
    Dendrou, Calliope A., Cortes, Adrian, Shipman, Lydia, Evans, Hayley G., Attfield, Kathrine E., Jostins, Luke, Barber, Thomas, Kaur, Gurman, Kuttikkatte, Subita Balaram, Leach, Oliver A. et al. · 2016 · Science Translational Medicine
97. Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing
    Jiazhi Hu, Robin M. Meyers, Junchao Dong, Rohit A. Panchakshari, Frederick W. Alt, Richard L. Frock · 2016 · Nature Protocols
98. A Gene Regulatory Network Balances Neural and Mesoderm Specification during Vertebrate Trunk Development
    Mina Gouti, Julien Delile, Despina Stamataki, Filip J. Wymeersch, Yali Huang, Jens Kleinjung, Valerie A. Wilson, James Briscoe · 2017 · Developmental Cell
99. Sublethal cytochrome c release generates drug-tolerant persister cells
    Halime Kalkavan, Jinan Chen, Jeremy Chase Crawford, Giovanni Quarato, PATRICK J. FITZGERALD, Stephen W. G. Tait, Colin R. Goding, Douglas R. Green · 2022 · Cell
100. Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation
     Matatall, Katie A., Jeong, Mira, Chen, Siyi, Sun, Deqiang, Chen, Fengju, Mo, Qianxing, Kimmel, Marek, King, Katherine Y. · 2016 · Cell Reports