Genome engineering using the CRISPR-Cas9 system

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Items 501–600 of 1,083

1. Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids
   Amelia Lane, Katarina Jovanovic, Ciara Shortall, Daniele Ottaviani, Anna Brugulat-Panés, Nele Schwarz, Rosellina Guarascio, Matthew John Hayes, Arpad Palfi, Naomi Chadderton et al. · 2020 · Stem Cell Reports
2. TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance
   Xiang, Xianyuan, Werner, Georg, Bohrmann, Bernd, Liesz, Arthur, Mazaheri, Fargol, Capell, Anja, Feederle, Regina, Knuesel, Irene, Kleinberger, Gernot, Haass, Christian · 2016 · EMBO Molecular Medicine
3. Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation
   Masaki Tsuchiya, Yuji Hara, Masaki Okuda, Karin Itoh, Ryotaro Nishioka, Akifumi Shiomi, Kohjiro Nagao, Masayuki Mori, Yasuo Mori, Junichi Ikenouchi et al. · 2018 · Nature Communications
4. HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA
   Kareem N. Mohni, Sarah R. Wessel, Runxiang Zhao, Andrea C. Florian, Jessica W. Luzwick, Hillary M. Layden, Brandt F. Eichman, Petria S. Thompson, Kavi P.M. Mehta, David Cortez · 2018 · Cell
5. The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy
   Rastislav Horos, Magdalena Büscher, Rozemarijn Kleinendorst, Anne-Marie Alleaume, Abul K. Tarafder, Thomas Schwarzl, Dmytro Dziuba, Christian Tischer, Elisabeth M. Zielonka, Asli Adak et al. · 2019 · Cell
6. ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response
   Sankari Nagarajan, Shalini V. Rao, Joseph Sutton, Danya Cheeseman, Shanade Dunn, Evangelia K. Papachristou, Jose-Enrique Gonzalez Prada, Dominique‐Laurent Couturier, Sanjeev Srinivas Kumar, Kamal Kishore et al. · 2020 · Nature Genetics
7. Efficient, Rapid, and Sensitive Detection of Plant RNA Viruses With One-Pot RT-RPA–CRISPR/Cas12a Assay
   Rashid Aman, Ahmed Mahas, Tin Maršić, Norhan Hassan, Magdy M. Mahfouz · 2020 · Frontiers in Microbiology
8. Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice
   Andreas C. Chai, Miao Cui, Francesco Chemello, Hui zi Li, Kenian Chen, Wei Hong Tan, Ayhan Atmanli, John McAnally, Yu Zhang, Lin Xu et al. · 2023 · Nature Medicine
9. Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase
   He, Jiuya, Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E. · 2017 · Proceedings of the National Academy of Sciences
10. Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair
    Fade Gong, Thomas Clouaire, Marion Aguirrebengoa, Gaëlle Legube, Kyle M. Miller · 2017 · The Journal of Cell Biology
11. Application of CRISPR/Cas9-Based Gene Editing in HIV-1/AIDS Therapy
    Qiaoqiao Xiao, Deyin Guo, Shuliang Chen · 2019 · Frontiers in Cellular and Infection Microbiology
12. Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions
    Minfeng Ying, Duo You, Xiaobing Zhu, Limeng Cai, Siying Zeng, Xun Hu · 2021 · Redox Biology
13. EZH2 engages TGFβ signaling to promote breast cancer bone metastasis via integrin β1-FAK activation
    Lin Zhang, Jingkun Qu, Yutao Qi, Yimin Duan, Yu-Wen Huang, Zhifen Zhou, Ping Li, Jun Yao, Beibei Huang, Shuxing Zhang et al. · 2022 · Nature Communications
14. MAP7 family proteins regulate kinesin-1 recruitment and activation
    Hooikaas, Peter Jan, Martin, Maud, Mühlethaler, Tobias, Kuijntjes, Gert-Jan, Peeters, Cathelijn A.E., Katrukha, Eugene A., Ferrari, Luca, Stucchi, Riccardo, Verhagen, Daan G.F., van Riel, Wilhelmina E. et al. · 2019 · Journal of Cell Biology
15. Systematic analysis of ribophagy in human cells reveals bystander flux during selective autophagy
    An, Heeseon, Harper, J. Wade · 2018 · Nature Cell Biology
16. Generation of Myostatin Gene-Edited Channel Catfish (Ictalurus punctatus) via Zygote Injection of CRISPR/Cas9 System
    Karim M. Khalil, Medhat A. El-Ayat, Elsayed Khalifa, Samer Mohamed Daghash, Ahmed Elaswad, Michael E. Miller, Hisham Ahmed Abdelrahman, Zhi Ye, Ramjie Odin, David Drescher et al. · 2017 · Scientific Reports
17. Mechanosensing and Mechanoregulation of Endothelial Cell Functions
    Yun Hua Fang, David Wu, Konstantin G. Birukov · 2019 · Comprehensive physiology
18. RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells
    Diana Guallar, Xianju Bi, José Ángel Pardavila, Xin Huang, Carmen Sáenz, Xianle Shi, Hongwei Zhou, Francesco Faiola, Junjun Ding, Phensinee Haruehanroengra et al. · 2018 · Nature Genetics
19. Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
    Alicia M. Darnell, Arvind Rasi Subramaniam, Erin K. O’Shea · 2018 · Molecular Cell
20. Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation During DNA Replication
    Thelma M. Escobar, Ozgur Oksuz, Ricardo Saldaña-Meyer, Nicolas Descostes, Roberto Bonasio, Danny Reinberg · 2019 · Cell
21. Detection of genomic G-quadruplexes in living cells using a small artificial protein
    Ke‐wei Zheng, Jiayu Zhang, Yi-de He, Jia-yuan Gong, Cui-jiao Wen, Juan-nan Chen, Yu‐hua Hao, Yong Bo Zhao, Zheng Tan · 2020 · Nucleic Acids Research
22. A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death
    Zhi Ying Zhao, Xu Jie Xie, Wan Hua Li, Jun Liu, Zhe Chen, Ben Zhang, Ting Li, Song Lu Li, Jun Gang Lu, Liangren Zhang et al. · 2019 · iScience
23. ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL
    Gordana Wutz, René Ladurner, Brian Glenn St Hilaire, Roman R. Stocsits, Kota Nagasaka, Benoît Pignard, Adrian L. Sanborn, Wen Tang, Csilla Várnai, Miroslav Penchev Ivanov et al. · 2020 · eLife
24. Metabolic alterations in Parkinson’s disease astrocytes
    Tuuli-Maria Sonninen, Riikka H. Hämäläinen, Marja Koskuvi, Minna Oksanen, Anastasia Shakirzyanova, Sara Wojciechowski, Katja A. Puttonen, Nikolay V. Naumenko, Gundars Goldsteins, Nihay Laham-Karam et al. · 2020 · Scientific Reports
25. Liquid-like protein interactions catalyse assembly of endocytic vesicles
    Kasey J. Day, Grace Kago, Liping Wang, J. Blair Richter, Carl C. Hayden, Eileen M. Lafer, Jeanne C. Stachowiak · 2021 · Nature Cell Biology
26. Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform
    Kazuto Yoshimi, Takehito Kaneko, Birger Voigt, Tomoji Mashimo · 2014 · Nature Communications
27. Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing
    Li Zhang, Ngoc Tung Tran, Hairui Su, Rui Ying Wang, Yuheng Lu, Haiping Tang, Sayura Aoyagi, Ailan Guo, Alireza Khodadadi‐Jamayran, Dewang Zhou et al. · 2015 · eLife
28. Nanoparticle analysis sheds budding insights into genetic drivers of extracellular vesicle biogenesis
    Stephanie N. Hurwitz, Meghan M. Conlon, Mark A. Rider, Naomi C. Brownstein, David G. Meckes · 2016 · Journal of Extracellular Vesicles
29. Multidimensional chemical control of CRISPR–Cas9
    Basudeb Maji, Christopher L Moore, Bernd Zetsche, Sara E. Volz, Feng Zhang, Matthew D. Shoulders, Amit Choudhary · 2016 · Nature Chemical Biology
30. Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein?
    Victorio M. Pozo Devoto, Tomás Luis Falzone · 2017 · Disease Models & Mechanisms
31. Survival of pancreatic cancer cells lacking KRAS function
    Muzumdar, Mandar Deepak, Chen, Pan-Yu, Dorans, Kimberly Judith, Chung, Katherine Minjee, Bhutkar, Arjun, Hong, Erin, Noll, Elisa M., Sprick, Martin R., Trumpp, Andreas, Jacks, Tyler · 2017 · Nature Communications
32. PML isoform II plays a critical role in nuclear lipid droplet formation
    Yuki Ohsaki, Takeshi Kawai, Yukichika Yoshikawa, Jinglei Cheng, Eija Jokitalo, Toyoshi Fujimoto · 2016 · The Journal of Cell Biology
33. Recent Progress in CRISPR/Cas9 Technology
    Yue Mei, Yan Wang, Huiqian Chen, Zhong Sheng Sun, Xing‐Da Ju · 2016 · Journal of genetics and genomics/Journal of Genetics and Genomics
34. The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma
    Bill H. Diplas, Xujun He, Jacqueline A. Brosnan‐Cashman, Heng Liu, Lee H. Chen, Zhaohui Wang, Casey J. Moure, Patrick J. Killela, Daniel B. Loriaux, Eric Lipp et al. · 2018 · Nature Communications
35. Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy
    Jialang Zhuang, Jizhou Tan, Chenglin Wu, Jie Zhang, Ting Liu, Chunhai Fan, Jiaping Li, Yuanqing Zhang · 2020 · Nucleic Acids Research
36. Hyperactivation of HUSH complex function by Charcot–Marie–Tooth disease mutation in MORC2
    Iva A. Tchasovnikarova, Richard T. Timms, Christopher H. Douse, Rhys C. Roberts, Gordon Dougan, Robert E. Kingston, Yorgo Modis, Paul J. Lehner · 2017 · Nature Genetics
37. Xist Deletional Analysis Reveals an Interdependency between Xist RNA and Polycomb Complexes for Spreading along the Inactive X
    David Colognori, Hongjae Sunwoo, Andrea J. Kriz, Chen‐Yu Wang, Jeannie T. Lee · 2019 · Molecular Cell
38. Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models
    Hakim, Chady H., Kumar, Sandeep R. P., Pérez-López, Dennis O., Wasala, Nalinda B., Zhang, Dong, Yue, Yongping, Teixeira, James, Pan, Xiufang, Zhang, Keqing, Million, Emily D. et al. · 2021 · Nature Communications
39. Precision genome editing using cytosine and adenine base editors in mammalian cells
    Huang, Tony P., Newby, Gregory A., Liu, David R. · 2021 · Nature Protocols
40. SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X
    Chen‐Yu Wang, Teddy Jégu, Hsueh-Ping Catherine Chu, Hyun Jung Oh, Jeannie T. Lee · 2018 · Cell
41. β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis
    Jing Cai, Anirban Maitra, Robert A. Anders, Makoto Mark Taketo, Duojia Pan · 2015 · Genes & Development
42. Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells
    Riesenberg, Stephan, Maricic, Tomislav · 2018 · Nature Communications
43. Remodeling of ER‐exit sites initiates a membrane supply pathway for autophagosome biogenesis
    Liang Ge, Min Zhang, Samuel J. Kenny, Dawei Liu, Miharu Maeda, Kota Saito, Anandita Mathur, Ke Xu, Randy W. Schekman · 2017 · EMBO Reports
44. ZFAND1 Recruits p97 and the 26S Proteasome to Promote the Clearance of Arsenite-Induced Stress Granules
    Ankit Turakhiya, SUSANNE R. MEYER, Gabriella Marincola, Stefanie Böhm, Jens T. Vanselow, Andreas Schlösser, Kay Hofmann, Alexander Buchberger · 2018 · Molecular Cell
45. Ribosome collisions trigger cis-acting feedback inhibition of translation initiation
    Szymon Juszkiewicz, Greg Slodkowicz, Zhewang Lin, Paula Freire-Pritchett, Sew‐Yeu Peak‐Chew, Ramanujan S. Hegde · 2020 · eLife
46. Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2
    Vinzent Schulz, Somsuvro Basu, Sven‐Andreas Freibert, Holger Webert, Linda Boß, Ulrich Mühlenhoff, Fabien Pierrel, Lars‐Oliver Essen, Douglas M. Warui, Squire J. Booker et al. · 2022 · Nature Chemical Biology
47. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment
    Ping Wang, Mingyan Lin, Erika Pedrosa, Anastasia Hrabovsky, Zheng Zhang, Wenjun Guo, Herbert M. Lachman, Deyou Zheng · 2015 · Molecular Autism
48. CRISPR-Cas9D10A nickase-based genotypic and phenotypic screening to enhance genome editing
    Ting-Wei Will Chiang, Carlos le Sage, Delphine Larrieu, Mukerrem Demir, Stephen P. Jackson · 2016 · Scientific Reports
49. CRL4AMBRA1 is a master regulator of D-type cyclins
    Daniele Simoneschi, Gergely Róna, Nan Zhou, Yeon‐Tae Jeong, Shaowen Jiang, Giacomo Milletti, Arnaldo Arbini, Alfie O’sullivan, Andrew A. Wang, Sorasicha Nithikasem et al. · 2021 · Nature
50. The importance of DNA methylation of exons on alternative splicing
    Ronna Shayevitch, Dan Askayo, Ifat Keydar, Gil Ast · 2018 · RNA
51. Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition
    Annemarie Schwab, Zhigang Rao, Jie Zhang, André Gollowitzer, Katharina Siebenkäs, Nino Bindel, Elisabetta D’Avanzo, Ruthger van Roey, Yussuf Hajjaj, Ece Özel et al. · 2024 · Nature Cell Biology
52. The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
    Incontro, Salvatore, Díaz-Alonso, Javier, Iafrati, Jillian, Vieira, Marta, Asensio, Cedric S., Sohal, Vikaas S., Roche, Katherine W., Bender, Kevin J., Nicoll, Roger A. · 2018 · Nature Communications
53. Movement of accessible plasma membrane cholesterol by the GRAMD1 lipid transfer protein complex
    Naito, Tomoki, Ercan, Bilge, Krshnan, Logesvaran, Triebl, Alexander, Koh, Dylan Hong Zheng, Wei, Fan-Yan, Tomizawa, Kazuhito, Torta, Federico Tesio, Wenk, Markus R, Saheki, Yasunori · 2019 · eLife
54. Defining the stoichiometry of inositol 1,4,5-trisphosphate binding required to initiate Ca 2+ release
    Kamil J. Alzayady, Liwei Wang, Rahul Chandrasekhar, Larry E. Wagner, Filip Van Petegem, David I. Yule · 2016 · Science Signaling
55. PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders
    Pieter Stijnen, Bruno Ramos‐Molina, Stephen O’Rahilly, John W.M. Creemers · 2016 · Endocrine Reviews
56. iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy
    Kazuki Kodo, Sang‐Ging Ong, Fereshteh Jahanbani, Vittavat Termglinchan, Keiichi Hirono, Kolsoum InanlooRahatloo, Antje Ebert, Praveen Shukla, Oscar John Abilez, Jared M. Churko et al. · 2016 · Nature Cell Biology
57. CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2 N141I neurons
    Maitane Ortiz‐Virumbrales, Cesar L. Moreno, Ilya Kruglikov, Paula Marazuela, Andrew A. Sproul, Samson Jacob, Matthew Zimmer, Daniel J Paull, Bin Zhang, Eric E. Schadt et al. · 2017 · Acta Neuropathologica Communications
58. The Parkinson’s disease protein alpha-synuclein is a modulator of Processing-bodies and mRNA stability
    Erinc Hallacli, C. Kayatekin, S. Nazeen, Xiou H. Wang, Zoe R. Sheinkopf, Shubhangi Sathyakumar, S. Sarkar, Xin Jiang, Xian-Jun Dong, R. Di Maio et al. · 2022 · Cell
59. CRISPR-Cas9-mediated homology-directed repair for precise gene editing
    Hongyu Liao, Jiahao Wu, Nathan J. VanDusen, Yifei Li, Yanjiang Zheng · 2024 · Molecular Therapy — Nucleic Acids
60. A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells
    Hultquist, Judd F., Schumann, Kathrin, Woo, Jonathan M., Manganaro, Lara, McGregor, Michael J., Doudna, Jennifer, Simon, Viviana, Krogan, Nevan J., Marson, Alexander · 2016 · Cell Reports
61. Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing
    Carlson-Stevermer, Jared, Abdeen, Amr A., Kohlenberg, Lucille, Goedland, Madelyn, Molugu, Kaivalya, Lou, Meng, Saha, Krishanu · 2017 · Nature Communications
62. Microtubule minus-end regulation at spindle poles by an ASPM–katanin complex
    Kai Jiang, Lenka Řežábková, Shasha Hua, Qingyang Liu, Guido Capitani, Maarten A. F. Altelaar, Albert J. R. Heck, Richard A. Kammerer, Michel Olivier Steinmetz, Anna S. Akhmanova · 2017 · Nature Cell Biology
63. RNA Nanotechnology-Mediated Cancer Immunotherapy
    Yao‐Xin Lin, Yi Wang, Sara Blake, Mian Yu, Lin Mei, Hao Wang, Jinjun Shi · 2019 · Theranostics
64. Saturation variant interpretation using CRISPR prime editing
    Erwood, Steven, Bily, Teija M. I., Lequyer, Jason, Yan, Joyce, Gulati, Nitya, Brewer, Reid A., Zhou, Liangchi, Pelletier, Laurence, Ivakine, Evgueni A., Cohn, Ronald D. · 2022 · Nature Biotechnology
65. Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy
    Takahiko Nishiyama, Yu Zhang, Miao Cui, Hui zi Li, Efrain Sanchez‐Ortiz, John McAnally, Wei Hong Tan, Jiwoong Kim, Kenian Chen, Lin Xu et al. · 2022 · Science Translational Medicine
66. Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity
    Peter M.K. Westcott, Francesc Muyas, Haley Hauck, Olivia C. Ghirardelli Smith, Nathan J. Sacks, Zackery A. Ely, Alex M. Jaeger, William M. Rideout, Daniel Zhang, Arjun J. Bhutkar et al. · 2023 · Nature Genetics
67. Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis.
    Guo, Xing, Wang, Xiaorong, Wang, Zhiping, Banerjee, Sourav, Yang, Jing, Huang, Lan, Dixon, Jack E. · 2016 · Nature Cell Biology
68. Targeted disruption of sp7 and myostatin with CRISPR-Cas9 results in severe bone defects and more muscular cells in common carp
    Zhaomin Zhong, Pengfei Niu, Mingyong Wang, Guodong Huang, Shuhao Xu, Yi Sun, Xiaona Xu, Yi Hou, Xiaowen Sun, Yi‐Lin Yan et al. · 2016 · Scientific Reports
69. DNA-guided genome editing using the Natronobacterium gregoryi Argonaute
    Feng Gao, Xiao Z. Shen, Feng Jiang, Yongqiang Wu, Chunyu Han · 2016 · Nature Biotechnology · Retracted
70. C13orf31 (FAMIN) is a central regulator of immunometabolic function
    M. Zaeem Cader, Katharina Boroviak, Qifeng Zhang, Ghazaleh Assadi, Sarah L. Kempster, Gavin W. Sewell, Svetlana Saveljeva, Jonathan Ashcroft, Simon Clare, Subhankar Mukhopadhyay et al. · 2016 · Nature Immunology
71. Multilevel analyses of SCN5A mutations in arrhythmogenic right ventricular dysplasia/cardiomyopathy suggest non-canonical mechanisms for disease pathogenesis
    Anneline S.J.M. te Riele, Esperanza Agulló-Pascual, Cynthia A. James, Alejandra Leo‐Macías, Marina Cerrone, Mingliang Zhang, Xianming Lin, Bin Lin, Eli Rothenberg, Nara Lygia de Macena Sobreira et al. · 2016 · Cardiovascular Research
72. MicroRNA degradation by a conserved target RNA regulates animal behavior
    Angelo Bitetti, Allison C. Mallory, Elisabetta Golini, Claudia Carrieri, Héctor Carreño Gutiérrez, Emerald Perlas, Yuvia Alheli Perez-Rico, Glauco P. Tocchini‐Valentini, Anton James Enright, William Norton et al. · 2018 · Nature Structural & Molecular Biology
73. LncRNA PCNAP1 modulates hepatitis B virus replication and enhances tumor growth of liver cancer
    Jinyan Feng, Guang Yang, Yunxia Liu, Yuen Gao, Man Zhao, Yanan Bu, Hongfeng Yuan, Ying Yuan, Haolin Yun, Mingming Sun et al. · 2019 · Theranostics
74. Recurrent evolution of vertebrate transcription factors by transposase capture
    Rachel L. Cosby, Julius Judd, Ruiling Zhang, Alan Zhong, Nathaniel Garry, Ellen J. Pritham, Cédric Feschotte · 2021 · Science
75. Oxidative stress-mediated beta cell death and dysfunction as a target for diabetes management
    Svetlana Dinić, Jelena Arambašić Јovanović, Aleksandra S. Uskoković, Mirjana Mihailović, Nevena Grdović, Anja Tolić, Jovana Rajić, Marija Đorđević, Melita Vidaković · 2022 · Frontiers in Endocrinology
76. Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition
    LaRochelle, Jonathan R., Fodor, Michelle, Vemulapalli, Vidyasiri, Mohseni, Morvarid, Wang, Ping, Stams, Travis, LaMarche, Matthew J., Chopra, Rajiv, Acker, Michael G., Blacklow, Stephen C. · 2018 · Nature Communications
77. Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma
    Mondello, Patrizia, Tadros, Saber, Teater, Matt, Fontan, Lorena, Chang, Aaron Y., Jain, Neeraj, Yang, Haopeng, Singh, Shailbala, Ying, Hsia-Yuan, Chu, Chi-Shuen et al. · 2020 · Cancer Discovery
78. CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells
    Michael Ratz, Ilaria Testa, Stefan W. Hell, Stefan Jakobs · 2015 · Scientific Reports
79. CRISPR/Cas9-mediated genome editing of Epstein–Barr virus in human cells
    Kit‐San Yuen, Chi‐Ping Chan, Nok-Hei Mickey Wong, CH Ho, Ting‐Hin Ho, Ting Lei, Wen Deng, Sai Wah Tsao, Honglin Chen, Kin‐Hang Kok et al. · 2014 · Journal of General Virology
80. Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice
    Roman Maresch, Sebastian Mueller, Christian Veltkamp, Rupert Öllinger, Mathias Friedrich, Irina Heid, Katja Steiger, Julia Weber, Thomas Engleitner, Maxim Barenboim et al. · 2016 · Nature Communications
81. KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis
    Xu Qian, Xinjian Li, Zhumei Shi, Xiaoming Bai, Yan Xia, Yanhua Zheng, Daqian Xu, Feng Chen, Yongping You, Jing Fang et al. · 2019 · Molecular Cell
82. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease
    Rocchi, Altea, Yamamoto, Soh, Ting, Tabitha, Fan, Yuying, Sadleir, Katherine, Wang, Yigang, Zhang, Weiran, Huang, Sui, Levine, Beth, Vassar, Robert et al. · 2017 · PLOS Genetics
83. A peptide tag-specific nanobody enables high-quality labeling for dSTORM imaging
    David Virant, Bjoern Traenkle, Julia Maier, Philipp D. Kaiser, Mona Bodenhöfer, Christian Schmees, Ilijana Vojnovic, Borbála Pisak-Lukáts, Ulrike Endesfelder, Ulrich Rothbauer · 2018 · Nature Communications
84. Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis
    Guang Yang, Ying Yuan, Hongfeng Yuan, Jiapei Wang, Haolin Yun, Yu Geng, Man Zhao, Linhan Li, Yejing Weng, Zixian Liu et al. · 2020 · EMBO Reports
85. A modular toolbox for gRNA–Cas9 genome engineering in plants based on the GoldenBraid standard
    Marta Vázquez‐Vilar, Joan Miquel Bernabé‐Orts, Asun Fernández‐del‐Carmen, Pello Ziarsolo, José Blanca, Antonio Granell, Diego Orzáez · 2016 · Plant Methods
86. Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms
    Timothy A. Hore, Ferdinand von Meyenn, Mirunalini Ravichandran, Martin Bachman, Gabriella Ficz, David Oxley, Fátima Santos, Shankar Balasubramanian, Tomasz Piotr Jurkowski, Wolf Reik · 2016 · Proceedings of the National Academy of Sciences
87. CLAVATA Was a Genetic Novelty for the Morphological Innovation of 3D Growth in Land Plants
    Christopher Whitewoods, Joseph Cammarata, Zoe Nemec Venza, Stephanie Sang, Ashley D. Crook, Tsuyoshi Aoyama, Xiao Y. Wang, Manuel Waller, Yasuko Kamisugi, Andrew C. Cuming et al. · 2018 · Current Biology
88. Characterization of a filovirus (Měnglà virus) from Rousettus bats in China
    Xing‐Lou Yang, Chee Wah Tan, Danielle E. Anderson, Ren-Di Jiang, Bei Li, Wei Zhang, Yan Zhu, Xiao Fang Lim, Peng Zhou, Xiangling Liu et al. · 2018 · Nature Microbiology
89. CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites
    Rajeswari Jayavaradhan, Devin M. Pillis, Michael Goodman, Fan Zhang, Yue Zhang, Paul R. Andreassen, Punam Malik · 2019 · Nature Communications
90. Structural and functional characterization of G protein–coupled receptors with deep mutational scanning
    Jones, Eric M, Lubock, Nathan B, Venkatakrishnan, AJ, Wang, Jeffrey, Tseng, Alex M, Paggi, Joseph M, Latorraca, Naomi R, Cancilla, Daniel, Satyadi, Megan, Davis, Jessica E et al. · 2020 · eLife
91. Covalently closed circular DNA: The ultimate therapeutic target for curing HBV infections
    María Guadalupe Martínez, Anders C. Boyd, Emmanuel Combe, Barbara Testoni, Fabien Zoulim · 2021 · Journal of Hepatology
92. Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia
    Jinsoo Seo, Oleg Kritskiy, Lauren Ashley Watson, Scarlett J. Barker, Dilip Chandra Dey, Waseem Khan Raja, Yuan-Ta Lin, Tak Ko, Sukhee Cho, Jay Penney et al. · 2017 · Journal of Neuroscience
93. Efficient genome editing in Fusarium oxysporum based on CRISPR/Cas9 ribonucleoprotein complexes
    Qiang Wang, Paul A. Cobine, Jeffrey J. Coleman · 2018 · Fungal Genetics and Biology
94. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation
    Atsuya Nishiyama, Christopher B. Mulholland, Sebastian Bultmann, Satomi Kori, Akinori Endo, Yasushi Saeki, Weihua Qin, Carina Trummer, Yoshie Chiba, Haruka Yokoyama et al. · 2020 · Nature Communications
95. Metabolic Control by Heat Stress Determining Cell Fate to Ferroptosis for Effective Cancer Therapy
    Shaowei Xie, Wenshe Sun, Chunfu Zhang, Baijun Dong, Jingxing Yang, Mengfei Hou, Liqin Xiong, Biao Cai, Xuesong Liu, Wei Xue · 2021 · ACS Nano
96. Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling
    Feng Xie, Xiaoxue Zhou, Peng Su, Heyu Li, Yifei Tu, Jinjin Du, Chen Pan, Wei Dong Xiang, Min Zheng, Ke Jin et al. · 2022 · Nature Communications
97. SIKs control osteocyte responses to parathyroid hormone
    Marc Nathan Wein, Yanke Liang, Olga Göransson, Thomas B. Sundberg, Jinhua Wang, Elizabeth A. Williams, Maureen J. O’Meara, Nicolas Govea, Belinda Beqo, Shigeki Nishimori et al. · 2016 · Nature Communications
98. The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells
    Qiong Wang, Yilong Zou, Sonja Nowotschin, Sang Yong Kim, Qing V. Li, Chew-Li Soh, Jie Su, Chao Zhang, Weiping Shu, Qiaoran Xi et al. · 2016 · Cell stem cell
99. Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1
    William Christopher Risher, Namsoo Kim, Sehwon Koh, Ji-Eun Choi, Petar Mitev, Erin F. Spence, Louis‐Jan Pilaz, Dongqing Wang, Guoping Feng, Debra L. Silver et al. · 2018 · The Journal of Cell Biology
100. MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1
     Juming Yan, Stacey M. Allen, Elizabeth McDonald, Indrajit Das, Jeffrey Y. W. Mak, Ligong Liu, David P. Fairlie, Bronwyn S. Meehan, Zhenjun Chen, Alexandra Jane Corbett et al. · 2019 · Cancer Discovery