Vitamin D signalling pathways in cancer: potential for anticancer therapeutics

Nongenomic actions of steroid hormones

Lösel, R., & Wehling, M. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1009 · Cited by 980

Vitamin D-effects on skeletal and extraskeletal health and the need for supplementation

Wacker, M., & Holick, M. (2013) · Nutrients · doi:10.3390/nu5010111 · Cited by 733

Nutrients, foods, and colorectal cancer prevention

Song, M., Garrett, W. S., & Chan, A. T. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.12.035 · Cited by 700

Modulation of the immune system by UV radiation: More than just the effects of vitamin D?

Hart, P. H., Gorman, S., & Finlay-Jones, J. J. (2011) · Nature Reviews Immunology · doi:10.1038/nri3045 · Cited by 465

Differentiation therapy of leukemia: 3 decades of development.

Nowak, D., Stewart, D., & Koeffler, H. P. (2009) · Blood · doi:10.1182/blood-2009-01-198911 · Cited by 348

Photoimmunology: how ultraviolet radiation affects the immune system

Bernard, J. J., Gallo, R. L., & Krutmann, J. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-019-0185-9 · Cited by 329

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

Cooper, J. D., Smyth, D. J., Walker, N. M., Stevens, H., Burren, O. S., Wallace, C., Greissl, C., Ramos-Lopez, E., Hyppönen, E., Dunger, D. B., et al. (2011) · Diabetes · doi:10.2337/db10-1656 · Cited by 279

Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

Stambolsky, P., Tabach, Y., Fontemaggi, G., Weisz, L., Maor-Aloni, R., Sigfried, Z., Shiff, I., Kogan, I., Shay, M., Kalo, E., et al. (2010) · Cancer Cell · doi:10.1016/j.ccr.2009.11.025 · Cited by 245

Air pollution, environmental chemicals, and smoking may trigger vitamin D deficiency: Evidence and potential mechanisms

Mousavi, S. E., Amini, H., Heydarpour, P., Amini Chermahini, F., & Godderis, L. (2019) · Environment International · doi:10.1016/j.envint.2018.11.052 · Cited by 202

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

Callens, C., Coulon, S., Naudin, J., Radford-Weiss, I., Boissel, N., Raffoux, E., Wang, P. H. M., Agarwal, S., Tamouza, H., Paubelle, E., et al. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20091488 · Cited by 197

The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain

Cui, X., Pelekanos, M., Liu, P.-Y., Burne, T. H. J., McGrath, J. J., & Eyles, D. W. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.01.035 · Cited by 182

KDM6B/JMJD3 Histone Demethylase Is Induced by Vitamin D and Modulates Its Effects in Colon Cancer Cells

Pereira, F., Barbáchano, A., Silva, J., Bonilla, F., Campbell, M. J., Muñoz, A., & Larriba, M. J. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr399 · Cited by 177

Principal results of the VITamin D and OmegA-3 TriaL (VITAL) and updated meta-analyses of relevant vitamin D trials

Manson, J. E., Bassuk, S. S., & Buring, J. E. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105522 · Cited by 161

Vitamin D regulates microbiome-dependent cancer immunity

Giampazolias, E., Pereira da Costa, M., Lam, K. C., Lim, K. H. J., Cardoso, A., Piot, C., Chakravarty, P., Blasche, S., Patel, S., Biram, A., et al. (2024) · Science · doi:10.1126/science.adh7954 · Cited by 151

Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management

Slominski, A. T., Brożyna, A. A., Zmijewski, M. A., Jóźwicki, W., Jetten, A. M., Mason, R. S., Tuckey, R. C., & Elmets, C. A. (2017) · Laboratory Investigation · doi:10.1038/labinvest.2017.3 · Cited by 136

20-Hydroxycholecalciferol, Product of Vitamin D3 Hydroxylation by P450scc, Decreases NF-κB Activity by Increasing IκBα Levels in Human Keratinocytes

Janjetovic, Z., Zmijewski, M. A., Tuckey, R. C., DeLeon, D. A., Nguyen, M. N., Pfeffer, L. M., & Slominski, A. T. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005988 · Cited by 130

Vitamin D and pancreas: The role of sunshine vitamin in the pathogenesis of diabetes mellitus and pancreatic cancer

Altieri, B., Grant, W. B., Della Casa, S., Orio, F., Pontecorvi, A., Colao, A., Sarno, G., & Muscogiuri, G. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1136922 · Cited by 113

High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives

Janjetovic, Z., Brozyna, A. A., Tuckey, R. C., Kim, T.-K., Nguyen, M. N., Jozwicki, W., Pfeffer, S. R., Pfeffer, L. M., & Slominski, A. T. (2011) · British Journal of Cancer · doi:10.1038/bjc.2011.458 · Cited by 91

Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence

Graziano, S., Johnston, R., Deng, O., Zhang, J., & Gonzalo, S. (2016) · Oncogene · doi:10.1038/onc.2016.77 · Cited by 60

A review of vitamin D and Parkinson's disease

Peterson, A. L. (2014) · Maturitas · doi:10.1016/j.maturitas.2014.02.012 · Cited by 48

Vitamin D status and risk for malignant cutaneous melanoma: recent advances

Ombra, M. N., Paliogiannis, P., Doneddu, V., Sini, M. C., Colombino, M., Rozzo, C., Stanganelli, I., Tanda, F., Cossu, A., & Palmieri, G. (2017) · European Journal of Cancer Prevention · doi:10.1097/cej.0000000000000334 · Cited by 39

Correlation of Serum Vitamin D, Adipose Tissue Vitamin D Receptor, and Peroxisome Proliferator-Activated Receptor γ in Women with Gestational Diabetes Mellitus

Wang, H.-Y., She, G.-T., Sun, L.-Z., Lu, H., Wang, Y.-P., Miao, J., Liu, K.-Z., Sun, C.-F., & Ju, H.-H. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000480 · Cited by 18

Dose-Response Relationship between Serum Retinol Levels and Survival in Patients with Colorectal Cancer: Results from the DACHS Study

Maalmi, H., Walter, V., Jansen, L., Owen, R. W., Ulrich, A., Schöttker, B., Chang-Claude, J., Hoffmeister, M., & Brenner, H. (2018) · Nutrients · doi:10.3390/nu10040510 · Cited by 16