p53 and metabolism

On the origin of cancer cells

Warburg, O. (1956) · Science · doi:10.1126/science.123.3191.309 · Cited by 13,425

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., & Thompson, C. B. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.002 · Cited by 4,088

Development by Self-Digestion

Levine, B., & Klionsky, D. J. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00099-1 · Cited by 3,728

Blinded by the Light: The Growing Complexity of p53

Vousden, K. H., & Prives, C. (2009) · Cell · doi:10.1016/j.cell.2009.04.037 · Cited by 3,163

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Christofk, H. R., Vander Heiden, M. G., Harris, M. H., Ramanathan, A., Gerszten, R. E., Wei, R., Fleming, M. D., Schreiber, S. L., & Cantley, L. C. (2008) · Nature · doi:10.1038/nature06734 · Cited by 2,820

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

DeBerardinis, R. J., Mancuso, A., Daikhin, E., Nissim, I., Yudkoff, M., Wehrli, S., & Thompson, C. B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709747104 · Cited by 2,622

A model for p53-induced apoptosis

Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., & Vogelstein, B. (1997) · Nature · doi:10.1038/38525 · Cited by 2,500

Cancer cell metabolism: warburg and beyond

Hsu, P. P., & Sabatini, D. M. (2008) · Cell · doi:10.1016/j.cell.2008.08.021 · Cited by 2,452

p53 in health and disease

Vousden, K. H., & Lane, D. P. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2147 · Cited by 2,351

DRAGO (KIAA0247), a New DNA Damage–Responsive, p53-Inducible Gene That Cooperates With p53 as Oncosuppressor

Polato, F., Rusconi, P., Zangrossi, S., Morelli, F., Boeri, M., Musi, A., Marchini, S., Castiglioni, V., Scanziani, E., Torri, V., et al. (2014) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dju053 · Cited by 30

p53 and its mutants on the slippery road from stemness to carcinogenesis

Molchadsky, A., & Rotter, V. (2017) · Carcinogenesis · doi:10.1093/carcin/bgw092 · Cited by 30

Shifting the paradigms for tumor suppression: lessons from the p53 field

Barnoud, T., Indeglia, A., & Murphy, M. E. (2021) · Oncogene · doi:10.1038/s41388-021-01852-z · Cited by 31

Chaperone-mediated autophagy and disease: Implications for cancer and neurodegeneration

Gómez‐Sintes, R., & Arias, E. (2021) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2021.101025 · Cited by 29

Cytoplasmic p53 aggregates accumulated in p53-mutated cancer correlate with poor prognosis

Iwahashi, N., Ikezaki, M., Komohara, Y., Fujiwara, Y., Noguchi, T., Nishioka, K., Sakai, K., Nishio, K., Ueda, M., Ihara, Y., et al. (2022) · PNAS Nexus · doi:10.1093/pnasnexus/pgac128 · Cited by 29

Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus

Beam, J. E., Wagner, N. J., Lu, K., Parsons, J. B., Fowler, V. G., Rowe, S. E., & Conlon, B. P. (2023) · iScience · doi:10.1016/j.isci.2023.107942 · Cited by 29

LC3B globular structures correlate with survival in esophageal adenocarcinoma

El-Mashed, S., O’Donovan, T. R., Kay, E. W., Abdallah, A. R., Cathcart, M., O'Sullivan, J. N., O’Grady, A., Reynolds, J. V., O’Reilly, S., O’Sullivan, G. C., et al. (2015) · BMC Cancer · doi:10.1186/s12885-015-1574-5 · Cited by 29

Radiosensitization of glioma cells by TP53-induced glycolysis and apoptosis regulator knockdown is dependent on thioredoxin-1 nuclear translocation

Zhang, H., Gu, C., Yu, J., Wang, Z., Yuan, X., Yang, L., Wang, J., Jia, Y., Liu, J., & Liu, F. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.01.034 · Cited by 29

PGC-1α Regulates Translocated in Liposarcoma Activity: Role in Oxidative Stress Gene Expression

Sánchez‐Ramos, C., Tiérrez, A., Fabregat‐Andrés, Ó., Wild, B., Sánchez‐Cabo, F., Arduini, A., Dopazo, A., & Monsalve, M. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3643 · Cited by 29

E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells

Hatchi, E., Rodier, G., Lacroix, M., Caramel, J., Kirsh, O., Jacquet, C., Schrepfer, E., Lagarrigue, S., Linares, L. K., Lledo, G., et al. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20101995 · Cited by 33

Short-term magnesium deficiency upregulates sphingomyelin synthase and p53 in cardiovascular tissues and cells: relevance to the de novo synthesis of ceramide

Altura, B. M., Shah, N. C., Li, Z., Jiang, X., Zhang, A., Li, W., Zheng, T., Perez-Albela, J. L., & Altura, B. T. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00671.2010 · Cited by 29

Metabolic rewiring beyond Warburg in chronic lymphocytic leukemia: How much do we actually know?

Galicia-Vázquez, G., & Aloyz, R. S. (2018) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2018.12.003 · Cited by 30

HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53‐dependent mitochondrial apoptosis

Castelli, M., Piobbico, D., Chiacchiaretta, M., Brunacci, C., Pieroni, S., Bartoli, D., Gargaro, M., Fallarino, F., Puccetti, P., Soddu, S., et al. (2019) · EMBO Reports · doi:10.15252/embr.201948073 · Cited by 29

Ribosomal protein S3 selectively affects colon cancer growth by modulating the levels of p53 and lactate dehydrogenase

Alam, E., Maaliki, L., & Nasr, Z. (2020) · Molecular Biology Reports · doi:10.1007/s11033-020-05683-1 · Cited by 29

Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.

Tang, J., Agrawal, T., Cheng, Q., Qu, L., Brewer, M. D., Chen, J., & Yang, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055813 · Cited by 28

HSPA12A acts as a scaffolding protein to inhibit cardiac fibroblast activation and cardiac fibrosis

Mao, Q., Zhang, X., Yang, J., Kong, Q., Cheng, H., Yu, W., Cao, X., Li, Y., Li, C., Liu, L., et al. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.01.012 · Cited by 28

Metabolic rewiring of pancreatic ductal adenocarcinoma: New routes to follow within the maze

Olivares, O., & Vasseur, S. (2015) · International Journal of Cancer · doi:10.1002/ijc.29501 · Cited by 28

High-glycolytic cancers and their interplay with the body’s glucose demand and supply cycle

Mathews, E. H., Liebenberg, L., & Pelzer, R. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2010.09.006 · Cited by 28

Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells

Huang, Y., & Ratovitski, E. A. (2010) · Aging · doi:10.18632/aging.100249 · Cited by 28

Caloric Restriction Exacerbates Angiotensin II–Induced Abdominal Aortic Aneurysm in the Absence of p53

Gao, P., Zhang, H., Zhang, Q., Xia, F., Wu, H., Wang, M., Lu, Z., Wei, X., Yang, G., Yan, Z., et al. (2019) · Hypertension · doi:10.1161/hypertensionaha.118.12086 · Cited by 28

Long non-coding RNA-based glycolysis-targeted cancer therapy: feasibility, progression and limitations

Liu, R., Wang, X., Shen, Y., & He, A. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06247-7 · Cited by 28

Metformin Affects Olaparib Sensitivity through Induction of Apoptosis in Epithelial Ovarian Cancer Cell Lines

Gralewska, P., Gajek, A., Marczak, A., & Rogalska, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910557 · Cited by 29

Current insights into the regulation of programmed cell death by TP53 mutation in cancer

Su, Y., Sai, Y., Zhou, L., Liu, Z., Du, P., Wu, J., & Zhang, J. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1023427 · Cited by 29

p53 promotes peroxisomal fatty acid β-oxidation to repress purine biosynthesis and mediate tumor suppression

Zhao, J., Zhou, X., Chen, B., Lu, M., Wang, G., Elumalai, N., Tian, C., Zhang, J., Liu, Y., Chen, Z., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05625-2 · Cited by 28

Proteomic signatures associated with p53 mutational status in lung adenocarcinoma

Taguchi, A., Delgado, O., Çeliktaş, M., Katayama, H., Wang, H., Gazdar, A. F., & Hanash, S. (2014) · PROTEOMICS · doi:10.1002/pmic.201400378 · Cited by 28

Uncovering the Underlying Mechanisms of Cancer Metabolism through the Landscapes and Probability Flux Quantifications

Li, W., & Wang, J. (2020) · iScience · doi:10.1016/j.isci.2020.101002 · Cited by 27

Glut1 expression is increased by p53 reduction to switch metabolism to glycolysis during osteoblast differentiation

Ohnishi, T., Kusuyama, J., Bandow, K., & Matsuguchi, T. (2020) · Biochemical Journal · doi:10.1042/bcj20190888 · Cited by 28

Mutant p53 Attenuates Oxidative Phosphorylation and Facilitates Cancer Stemness through Downregulating miR-200c–PCK2 Axis in Basal-Like Breast Cancer

Chao, C.-H., Wang, C.-Y., Wang, C.-H., Chen, T.-W., Hsu, H.-Y., Huang, H.-W., Li, C., & Mai, R.-T. (2021) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-21-0098 · Cited by 29

Metabolic landscapes in sarcomas

MIALLOT, R., Galland, F., Millet, V., Blay, J., & Naquet, P. (2021) · Journal of Hematology & Oncology · doi:10.1186/s13045-021-01125-y · Cited by 29

Low-dose arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation

Ganapathy, S., Xiao, S., Seo, S.-J., Lall, R., Yang, M., Teng, X., Su, H., Shadfan, M., Ha, C. S., & Yuan, Z.-M. (2013) · Oncogene · doi:10.1038/onc.2013.81 · Cited by 27

Pathological axes of wound repair: Gastrulation revisited

Aller, M., Arias, J. I., & Árias, J. (2010) · Theoretical Biology and Medical Modelling · doi:10.1186/1742-4682-7-37 · Cited by 27

Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer

Broekman, K. E., Hof, M. A. J., Touw, D. J., Gietema, J. A., Nijman, H. W., Lefrandt, J. D., Reyners, A. K. L., & Jalving, M. (2020) · Investigational New Drugs · doi:10.1007/s10637-020-00920-7 · Cited by 26

On the selective killing of cold atmospheric plasma cancer treatment: Status and beyond

Yan, D., Horkowitz, A., Wang, Q., & Keidar, M. (2021) · Plasma Processes and Polymers · doi:10.1002/ppap.202100020 · Cited by 26

p53 protects against alcoholic fatty liver disease via ALDH2 inhibition

Yao, P., Zhang, Z., Liu, H., Jiang, P., Li, W., & Du, W. (2023) · The EMBO Journal · doi:10.15252/embj.2022112304 · Cited by 27

Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition

Saha, A., Zhao, S., Kindall, A., Wilder, C. S., Friedman, C. A., Clark, R., Georgiou, G., Stone, E. M., Kidane, D., & DiGiovanni, J. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02677-2 · Cited by 27

Uncovering metabolism in rhabdomyosarcoma

Monti, E., & Fanzani, A. (2015) · Cell Cycle · doi:10.1080/15384101.2015.1071746 · Cited by 26

Loss of LKB1 in high‐grade endometrial carcinoma: LKB1 is a novel transcriptional target of p53

Co, N. N., Iglesias, D. A., Celestino, J., Kwan, S., Mok, S. C., Schmandt, R. E., & Lu, K. H. (2014) · Cancer · doi:10.1002/cncr.28854 · Cited by 26

Induction of nuclear translocation of mutant cytoplasmic p53 by geranylgeranoic acid in a human hepatoma cell line

Iwao, C., & Shidoji, Y. (2014) · Scientific Reports · doi:10.1038/srep04419 · Cited by 26

Increased Oxidative Damage in Carriers of the Germline TP53 p.R337H Mutation

Macedo, G. S., da Motta, L. L., Giacomazzi, J., Netto, C. B. O., Manfredini, V., Vanzin, C. S., Vargas, C. R., Hainaut, P. L., Klamt, F., & Ashton‐Prolla, P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047010 · Cited by 26

The p53/Adipose-Tissue/Cancer Nexus

Zwezdaryk, K. J., Sullivan, D. E., & Saifudeen, Z. R. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00457 · Cited by 26

Major Vault Protein Promotes Hepatocellular Carcinoma Through Targeting Interferon Regulatory Factor 2 and Decreasing p53 Activity

Yu, H., Li, M., He, R., Fang, P., Wang, Q., Yu, Y., Wang, F., Zhou, L., Zhang, Y., Chen, A., et al. (2019) · Hepatology · doi:10.1002/hep.31045 · Cited by 26

RBM10, a New Regulator of p53

Jung, J. H., Lee, H., Zeng, S. X., & Lu, H. (2020) · Cells · doi:10.3390/cells9092107 · Cited by 27

mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging

Węsierska‐Gądek, J. (2010) · Aging · doi:10.18632/aging.100240 · Cited by 25

Metabolic modulation of chromatin: implications for DNA repair and genomic integrity

Liu, J. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00182 · Cited by 26

MYC Expression and Metabolic Redox Changes in Cancer Cells: A Synergy Able to Induce Chemoresistance

Marengo, B., Garbarino, O., Speciale, A., Monteleone, L., Traverso, N., & Domenicotti, C. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/7346492 · Cited by 25

Multi-omics analysis reveals the mechanisms of action and therapeutic regimens of traditional Chinese medicine, Bufei Jianpi granules: Implication for COPD drug discovery

Wang, H., Hou, Y., Ma, X., Cui, L., Bao, Y., Xie, Y., Li, S., Meng, X., Li, J., & Bai, G. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.153963 · Cited by 25

Sensing of p53 and EGFR Biomarkers Using High Efficiency SERS Substrates

Owens, P., Phillipson, N., Perumal, J., O’Connor, G. M., & Olivo, M. (2015) · Biosensors · doi:10.3390/bios5040664 · Cited by 25

Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis

Gannon, H., & Jones, S. N. (2012) · Genes & Cancer · doi:10.1177/1947601912455324 · Cited by 25

Genetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes

Jacovas, V. C., Rovaris, D. L., Peréz, O., de Azevedo, S., Macedo, G. S., Sandoval, J. R., Salazar‐Granara, A., Villena, M., Dugoujon, J., Bisso‐Machado, R., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0137823 · Cited by 27

Discovery of ‘click’ 1,2,3-triazolium salts as potential anticancer drugs

Steiner, I., Stojanović, N., Bolje, A., Brozović, A., Polančec, D., Ambriović‐Ristov, A., Stojković, M. R., Piantanida, I., Eljuga, D., Košmrlj, J., et al. (2016) · Radiology and Oncology · doi:10.1515/raon-2016-0027 · Cited by 25

The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40

Secchiero, P., Toffoli, B., Melloni, E., Agnoletto, C., Monasta, L., & Zauli, G. (2013) · Acta Diabetologica · doi:10.1007/s00592-013-0476-8 · Cited by 25

Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms

Butturini, E., Butera, G., Pacchiana, R., de Prati, A. C., Mariotto, S., & Donadelli, M. (2021) · Cells · doi:10.3390/cells10113149 · Cited by 25

Impaired Mitochondrial Metabolism and Mammary Carcinogenesis

Yadava, N., Schneider, S. S., Jerry, D. J., & Kim, C. G. (2012) · Journal of Mammary Gland Biology and Neoplasia · doi:10.1007/s10911-012-9271-3 · Cited by 24

Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours

Beloueche‐Babari, M., Box, C., Arunan, V., Parkes, H. G., Valenti, M. R., Brandon, A. D. H., Jackson, L. E., Eccles, S. A., & Leach, M. O. (2015) · British Journal of Cancer · doi:10.1038/bjc.2015.86 · Cited by 24

GAMT joins the p53 network: Branching into metabolism

Ide, T., Chu, K., Aaronson, S. A., & Lee, S. W. (2010) · Cell Cycle · doi:10.4161/cc.9.9.11473 · Cited by 24

18F-FDG semi-quantitative parameters and biological prognostic factors in locally advanced breast cancer

Vicente, A. M. G., Castrejón, Á. S., Calatayud, F. R., Madero, V. M., Garrido, M. J. M., Martín, A. L., García, J. M. C., Woll, J. P. P., López-Muñíz, I. C., & Muñoz, A. P. (2012) · Revista Española de Medicina Nuclear e Imagen Molecular · doi:10.1016/j.remn.2011.12.001 · Cited by 24

AMP-activated protein kinase regulates autophagic protection against cisplatin-induced tissue injury in the kidney

Wei, L., Chen, W., Zou, Y., Huang, H., Pan, B., Jin, S., Huang, R., Nie, S., & Kong, G. (2015) · Genetics and Molecular Research · doi:10.4238/2015.october.5.13 · Cited by 24

Effects of Gui Zhu Yi Kun formula on the P53/AMPK pathway of autophagy in granulosa cells of rats with polycystic ovary syndrome

Xing, Y., Liu, Y., Liu, X., Wang, S.-L., Li, P., Lin, X.-H., Sui, C., Xu, C., Qi, B., & Tong, Q. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.4384 · Cited by 25

p53: An Attractive Therapeutic Target for Cancer

Patel, K. R., & Patel, H. D. (2019) · Current Medicinal Chemistry · doi:10.2174/1573406415666190621094704 · Cited by 24

Cross‐talk between Myc and p53 in B‐cell lymphomas

Li, Y., Yu, T., & Young, K. H. (2019) · Chronic Diseases and Translational Medicine · doi:10.1016/j.cdtm.2019.08.001 · Cited by 27

TP53 mutations in head and neck cancer cells determine the Warburg phenotypic switch creating metabolic vulnerabilities and therapeutic opportunities for stratified therapies

Wilkie, M. D., Anaam, E. A., Lau, A., Rubbi, C. P., Jones, T. M., Boyd, M. T., & Vlatković, N. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.02.032 · Cited by 23

Metabolic reprogramming of glutamine involved in tumorigenesis, multidrug resistance and tumor immunity

Wang, X., Xiao-xia, Y., Peng-Fei, S., Zong-Xue, Z., & Xiu-li, G. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175323 · Cited by 23

p53 and Metabolism: The GAMT Connection

Zhu, Y. Y., & Prives, C. L. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.10.026 · Cited by 23

Antagonistic role of natural compounds in mTOR-mediated metabolic reprogramming

Cerella, C., Gaigneaux, A., Dicato, M. A., & Diederich, M. F. (2014) · Cancer Letters · doi:10.1016/j.canlet.2014.02.008 · Cited by 23

Fluorine-18 Fluorodeoxyglucose Uptake in Hepatocellular Carcinoma: Correlation with Glucose Transporters and p53 Expression

Brito, A., Abrantes, A. M., Ribeiro, M., Oliveira, R. C., Casalta‐Lopes, J., Gonçalves, A. C., Sarmento‐Ribeiro, A. B., Tralhão, J. G., & Botelho, M. F. (2015) · Journal of Clinical and Experimental Hepatology · doi:10.1016/j.jceh.2015.05.003 · Cited by 23

Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer

Davidson, L. A., Callaway, E. S., Kim, E.-J., Weeks, B. R., Fan, Y., Allred, C. D., & Chapkin, R. S. (2015) · Cancer Research · doi:10.1158/0008-5472.can-15-1706 · Cited by 23

DREF plays multiple roles during Drosophila development

Tuệ, N. T., Yoshioka, Y., Mizoguchi, M., Yoshida, H., Zurita, M., & Yamaguchi, M. (2017) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2017.03.004 · Cited by 23

BTK blocks the inhibitory effects of MDM2 on p53 activity

Rada, M., Althubiti, M., Ekpenyong‐Akiba, A. E., Lee, K.-G., Lam, K., Fedorova, O., Barlev, N. A., & Macip, S. (2017) · Oncotarget · doi:10.18632/oncotarget.22543 · Cited by 23

Zinc cooperates with p53 to inhibit the activity of mitochondrial aconitase through reactive oxygen species accumulation

Xue, Y., Liu, Y., Su, J., Li, J., Wu, Y., Guo, R., Yu, B., Yan, X., Zhang, L., Sun, L., et al. (2019) · Cancer Medicine · doi:10.1002/cam4.2130 · Cited by 23

Investigation of tumor hypoxia using a two-enzyme system for in vitro generation of oxygen deficiency

Askoxylakis, V., Millonig, G., Wirkner, U., Schwager, C., Rana, S., Altmann, A., Haberkorn, U., Debus, J., Mueller, S., & Huber, P. E. (2011) · Radiation Oncology · doi:10.1186/1748-717x-6-35 · Cited by 23

Advanced strategy for cancer detection based on volatile organic compounds in breath

Jia, Z., Jiang, Y., Shang, T., Cao, H., Li, J., Lin, C., Pu, P., Xu, H., Liu, Y., Huang, Y., et al. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03526-4 · Cited by 23

Be quiet and you'll keep young: does mTOR underlie p53 action in protecting against senescence by favoring quiescence?

Dulić, V. (2011) · Aging · doi:10.18632/aging.100257 · Cited by 22

Emerging Role of Autophagy in the Development and Progression of Oral Squamous Cell Carcinoma

El-Aziz, Y. S. A., Leck, L. Y. W., Jansson, P. J., & Sahni, S. (2021) · Cancers · doi:10.3390/cancers13246152 · Cited by 22

The crosstalk of the human microbiome in breast and colon cancer: A metabolomics analysis

Mukherjee, A. G., Wanjari, U. R., Bradu, P., Murali, R., Kannampuzha, S., Loganathan, T., Doss, C. G. P., Arun Prakash, B. P., Renu, K., Dey, A., et al. (2022) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2022.103757 · Cited by 22

Metabolic interventions combined with CTLA-4 and PD-1/PD-L1 blockade for the treatment of tumors: mechanisms and strategies

Liao, L., Xu, H., Zhao, Y., & Zheng, X. (2023) · Frontiers of Medicine · doi:10.1007/s11684-023-1025-7 · Cited by 22

A Low-dose Arsenic-induced p53 Protein-mediated Metabolic Mechanism of Radiotherapy Protection

Ganapathy, S., Xiao, S., Yang, M., Qi, M., Choi, D. E., Ha, C. S., Little, J. B., & Yuan, Z.-M. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.531020 · Cited by 22

Oxygenomics in environmental stress

Sone, H., Akanuma, H., & Fukuda, T. (2010) · Redox Report · doi:10.1179/174329210x12650506623843 · Cited by 22

Constitutive and induced functions of the p53 gene

Zheltukhin, A. O., & Chumakov, P. M. (2010) · Biochemistry (Moscow) · doi:10.1134/s0006297910130110 · Cited by 23

Metabolic characterization of cultured mammalian cells by mass balance analysis, tracer labeling experiments and computer-aided simulations

Okahashi, N., Kohno, S., Kitajima, S., Matsuda, F., Takahashi, C., & Shimizu, H. (2015) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2015.04.003 · Cited by 22

Phase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies

Wang, Y., Jankú, F., Piha-Paul, S. A., Hess, K. R., Broaddus, R. R., Liu, L., Shi, N., Overman, M. J., Kopetz, S., Subbiah, V., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-58366-z · Cited by 22

Thyroid Cancer Stem-Like Cells: From Microenvironmental Niches to Therapeutic Strategies

Grassi, E., Ghiandai, V., & Persani, L. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10071455 · Cited by 23

Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study

Brändstedt, J., Wangefjord, S., Borgquist, S., Nodin, B., Eberhard, J., Manjer, J., & Jirström, K. (2013) · Journal of Translational Medicine · doi:10.1186/1479-5876-11-293 · Cited by 22

Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation

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