The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Cancer biology and NuRD: a multifaceted chromatin remodelling complex
Open accessAbstract
The nucleosome remodelling and histone deacetylase (NuRD; also known as Mi-2) complex regulates gene expression at the level of chromatin. The NuRD complex has been identified — using both genetic and molecular analyses — as a key determinant of differentiation in mouse embryonic stem cells and during development in various model systems. Similar to other chromatin remodellers, such as SWI/SNF and Polycomb complexes, NuRD has also been implicated in the regulation of transcriptional events that are integral to oncogenesis and cancer progression. Emerging molecular details regarding the recruitment of NuRD to specific loci during development, and the modulation of these events in cancer, are used to illustrate how the inappropriate localization of the complex could contribute to tumour biology.
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Cites
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“Other NuRD complex subunits have also been shown to have post-translational modifications, such as phosphorylation and acetylatio”
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Metadata
- Authors
- Lai, A. Y., & Wade, P. A.
- Venue
- Nature Reviews Cancer
- Published
- 2011-07-07
- Volume
- 11
- Issue
- 8
- Pages
- 588-596
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2089263351
- Cited by
- 539
- References
- 12
- FWCI
- 2.26
- Type
- journal article
- Language
- en
- Open access
- green
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