Cited by 460Evolution and Genetic DynamicsGenetic diversity and population structureGenetic Associations and Epidemiology

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Adaptation–not by sweeps alone

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Pritchard, Jonathan K., Di Rienzo, Anna·2010·Nature Reviews Genetics

DOI 10.1038/nrg2880PMC PMC4652788

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Abstract

There has been recent progress in identifying selective sweeps underlying a range of adaptations. Jonathan Pritchard and Anna Di Rienzo argue that many adaptive events in natural populations may occur by polygenic adaptation, which would largely go undetected by conventional methods for detecting selection.

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Authors: Pritchard, J. K., & Di Rienzo, A.
Affiliations: Howard Hughes Medical Institute (US)
ORCID: Pritchard, Jonathan K.
Venue: Nature Reviews Genetics
Publisher: Springer Science and Business Media LLC
Published: 2010-09-14
Volume: 11
Issue: 10
Pages: 665-667
ISSN: 1471-0056 (ISSN-L)
1471-0064
DOI: 10.1038/nrg2880
PMC: PMC4652788
OpenAlex: W1525285200
Cited by: 445
References: 24
Citations by year: 2026: 16 · 2025: 22 · 2024: 20 · 2023: 16 · 2022: 19 · 2021: 37 · 2020: 43 · 2019: 27 · 2018: 41 · 2017: 36 · 2016: 32 · 2015: 35 · 2014: 30 · 2013: 23 · 2012: 29
FWCI: 2.40
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Nature Reviews Genetics (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Howard Hughes Medical Institute
National Institutes of Health
National Institute of Mental Health (R01MH084703, MH84703)
National Institute of General Medical Sciences (GM79558, R01GM079558)
National Institute of Diabetes and Digestive and Kidney Diseases (DK 56670, R01DK056670)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords: polygenic adaptation, selective sweeps, natural selection, adaptation, quantitative traits
MeSH terms: Adaptation, Physiological, Animals, Genetics, Population, Humans, Selection, Genetic, Evolution, Molecular, Multifactorial Inheritance

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Adaptation–not by sweeps alone

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