Cited by 460Evolution and Genetic DynamicsGenetic diversity and population structureGenetic Associations and Epidemiology

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Adaptation–not by sweeps alone

Open access

Pritchard, Jonathan K., Di Rienzo, Anna·2010·Nature Reviews Genetics

DOI 10.1038/nrg2880PMC PMC4652788

Open this paper in CoChat — free account Open PDF

Abstract

There has been recent progress in identifying selective sweeps underlying a range of adaptations. Jonathan Pritchard and Anna Di Rienzo argue that many adaptive events in natural populations may occur by polygenic adaptation, which would largely go undetected by conventional methods for detecting selection.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1038/nrg2880

Cites

24 of 24 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Introduction to Quantitative Genetics.
Edwards, A. W. F., & Falconer, D. S. (1982) · Biometrics · doi:10.2307/2529912 · Cited by 21,447
Introduction to Quantitative Genetics
J.-M., G., & Falconer, D. S. (1962) · Population · doi:10.2307/1525780 · Cited by 3,773
The hitch-hiking effect of a favourable gene
Smith, J. M., & Haigh, J. (1974) · Genetical Research · doi:10.1017/s0016672300014634 · Cited by 3,415
The hitch-hiking effect of a favourable gene
Smith, J. M., & Haigh, J. (2007) · Genetics Research · doi:10.1017/s0016672308009579 · Cited by 2,675
The causes of molecular evolution
Gillespie, J. H. (1992) · Choice Reviews Online · doi:10.5860/choice.30-2064 · Cited by 1,214
Positive Natural Selection in the Human Lineage
Sabeti, P. C., Schaffner, S. F., Fry, B., Lohmueller, J., Varilly, P., Shamovsky, O., Palma, A., Mikkelsen, T. S., Altshuler, D., & Lander, E. S. (2006) · Science · doi:10.1126/science.1124309 · Cited by 1,157
Untitled work
Hermisson (2005) · doi:10.1534/genetics.104.036947 · Cited by 1,009
The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation
Pritchard, J. K., Pickrell, J. K., & Coop, G. (2010) · Current Biology · doi:10.1016/j.cub.2009.11.055 · Cited by 932
Self-citation
Understanding quantitative genetic variation
Barton, N., & Keightley, P. D. (2002) · Nature Reviews Genetics · doi:10.1038/nrg700 · Cited by 833
Genome-wide association analysis identifies 20 loci that influence adult height
Initiative, D. G., Weedon, M. N., The Wellcome Trust Case Control Consortium, Cambridge GEM Consortium, Lango, H., Lindgren, C. M., Wallace, C., Evans, D. M., Mangino, M., Freathy, R. M., et al. (2008) · Nature Genetics · doi:10.1038/ng.121 · Cited by 826

Flagged first, then by citations

Show all 24 references

Sorted by citations

Ecological genomics of local adaptation
Savolainen, O., Lascoux, M., & Merilä, J. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3522 · Cited by 1,463
The evolutionary origins of pesticide resistance
Hawkins, N. J., Bass, C., Dixon, A. L., & Neve, P. (2018) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12440 · Cited by 908
A practical guide to environmental association analysis in landscape genomics
Rellstab, C., Gugerli, F., Eckert, A. J., Hancock, A. M., & Holderegger, R. (2015) · Molecular Ecology · doi:10.1111/mec.13322 · Cited by 881
Detecting Natural Selection in Genomic Data
Vitti, J. J., Grossman, S. R., & Sabeti, P. C. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-111212-133526 · Cited by 694
The relative power of genome scans to detect local adaptation depends on sampling design and statistical method
Lotterhos, K. E., & Whitlock, M. C. (2015) · Molecular Ecology · doi:10.1111/mec.13100 · Cited by 588
Progress and promise of genome-wide association studies for human complex trait genetics
Stranger, B. E., Stahl, E. A., & Raj, T. (2011) · Genetics · doi:10.1534/genetics.110.120907 · Cited by 567
Evaluation of demographic history and neutral parameterization on the performance of FST outlier tests
Lotterhos, K. E., & Whitlock, M. C. (2014) · Molecular Ecology · doi:10.1111/mec.12725 · Cited by 534
Genomic signatures of selection at linked sites: unifying the disparity among species
Cutter, A. D., & Payseur, B. A. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3425 · Cited by 467
Variable prediction accuracy of polygenic scores within an ancestry group
Mostafavi, H., Harpak, A., Agarwal, I., Conley, D., Pritchard, J. K., & Przeworski, M. (2020) · eLife · doi:10.7554/elife.48376 · Cited by 457
Self-citation
Evolutionary genetics of plant adaptation
Anderson, J. T., Willis, J. H., & Mitchell‐Olds, T. (2011) · Trends in Genetics · doi:10.1016/j.tig.2011.04.001 · Cited by 443
QST–FST comparisons: evolutionary and ecological insights from genomic heterogeneity
Leinonen, T., McCairns, R. J. S., O'Hara, R. B., & Merilä, J. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3395 · Cited by 422
Polygenic adaptation: a unifying framework to understand positive selection
Barghi, N., Hermisson, J., & Schlötterer, C. (2020) · Nature Reviews Genetics · doi:10.1038/s41576-020-0250-z · Cited by 425
Identification of Genomic Regions Associated with Phenotypic Variation between Dog Breeds using Selection Mapping
Vaysse, A., Ratnakumar, A., Derrien, T., Axelsson, E., Pielberg, G., Sigurðsson, S., Fall, T., Seppälä, E. H., Hansen, M. S., Lawley, C., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002316 · Cited by 399
Signatures of negative selection in the genetic architecture of human complex traits
Zeng, J., de Vlaming, R., Wu, Y., Robinson, M. R., Lloyd-Jones, L. R., Yengo, L., Yap, C. X., Xue, A., Sidorenko, J., McRae, A. F., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0101-4 · Cited by 391
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
Diabetes Genetics Replication and Meta-analysis Consortium, Stahl, E. A., Myocardial Infarction Genetics Consortium, Wegmann, D., Trynka, G., Gutierrez-Achury, J., Do, R., Voight, B. F., Kraft, P., Chen, R., et al. (2012) · Nature Genetics · doi:10.1038/ng.2232 · Cited by 388
On Detecting Incomplete Soft or Hard Selective Sweeps Using Haplotype Structure
Ferrer-Admetlla, A., Liang, M., Korneliussen, T. S., & Nielsen, R. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu077 · Cited by 382
Half a century of genetic interaction between farmed and wild Atlantic salmon: Status of knowledge and unanswered questions
Glover, K. A., Solberg, M. F., McGinnity, P., Hindar, K., Verspoor, E., Coulson, M. W., Hansen, M. M., Araki, H., Skaala, Ø., & Svåsand, T. (2017) · Fish and Fisheries · doi:10.1111/faf.12214 · Cited by 359
The genetic differentiation at quantitative trait loci under local adaptation
Corre, V. L., & Kremer, A. (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2012.05479.x · Cited by 364
Population genomics of Populus trichocarpa identifies signatures of selection and adaptive trait associations
Evans, L. M., Slavov, G. T., Rodgers‐Melnick, E., Martin, J., Ranjan, P., Muchero, W., Brunner, A. M., Schackwitz, W., Gunter, L. E., Chen, J., et al. (2014) · Nature Genetics · doi:10.1038/ng.3075 · Cited by 348
Evidence of widespread selection on standing variation in Europe at height-associated SNPs
Turchin, M. C., Chiang, C. W., Palmer, C. D., Sankararaman, S., Reich, D., Genetic Investigation of ANthropometric Traits (GIANT) Consortium, & Hirschhorn, J. N. (2012) · Nature Genetics · doi:10.1038/ng.2368 · Cited by 329
Genome scan methods against more complex models: when and how much should we trust them?
de Villemereuil, P., Frichot, É., Bazin, É., François, O., & Gaggiotti, O. E. (2014) · Molecular Ecology · doi:10.1111/mec.12705 · Cited by 306
Genetic redundancy fuels polygenic adaptation in Drosophila
Barghi, N., Tobler, R., Nolte, V., Jakšić, A. M., Mallard, F., Otte, K. A., Dolezal, M., Taus, T., Kofler, R., & Schlötterer, C. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000128 · Cited by 293
Monitoring adaptive genetic responses to environmental change
Hansen, M. M., Olivieri, I., Waller, D. M., Nielsen, E. E., & The GeM Working Group (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2011.05463.x · Cited by 307
Using neutral, selected, and hitchhiker loci to assess connectivity of marine populations in the genomic era
Gagnaire, P., Broquet, T., Aurelle, D., Viard, F., Souissi, A., Bonhomme, F., Arnaud‐Haond, S., & Bierne, N. (2015) · Evolutionary Applications · doi:10.1111/eva.12288 · Cited by 278
Thinking About the Evolution of Complex Traits in the Era of Genome-Wide Association Studies
Sella, G., & Barton, N. (2019) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-083115-022316 · Cited by 276
Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies
Cho, J. H., & Feldman, M. A. (2015) · Nature Medicine · doi:10.1038/nm.3897 · Cited by 267
Forensic genetic analysis of bio-geographical ancestry
Phillips, C. (2015) · Forensic Science International Genetics · doi:10.1016/j.fsigen.2015.05.012 · Cited by 265
On the maintenance of genetic variation and adaptation to environmental change: considerations from population genomics in fishes
Bernatchez, L. (2016) · Journal of Fish Biology · doi:10.1111/jfb.13145 · Cited by 252
Evaluation of redundancy analysis to identify signatures of local adaptation
Capblancq, T., Luu, K., Blum, M. G. B., & Bazin, É. (2018) · Molecular Ecology Resources · doi:10.1111/1755-0998.12906 · Cited by 239
Admixture facilitates genetic adaptations to high altitude in Tibet
Jeong, C., Alkorta‐Aranburu, G., Basnyat, B., Neupane, M., Witonsky, D., Pritchard, J. K., Beall, C. M., & Rienzo, A. D. (2014) · Nature Communications · doi:10.1038/ncomms4281 · Cited by 248
Self-citation
Signatures of local adaptation in candidate genes of oaks ( Quercus spp.) with respect to present and future climatic conditions
Rellstab, C., Zoller, S., Walthert, L., Lesur, I., Pluess, A. R., Graf, R., Bodénès, C., Sperisen, C., Kremer, A., & Gugerli, F. (2016) · Molecular Ecology · doi:10.1111/mec.13889 · Cited by 232
THE GENETIC ARCHITECTURE OF REPRODUCTIVE ISOLATION DURING SPECIATION-WITH-GENE-FLOW IN LAKE WHITEFISH SPECIES PAIRS ASSESSED BY RAD SEQUENCING
Gagnaire, P., Pavey, S. A., Normandeau, É., & Bernatchez, L. (2013) · Evolution · doi:10.1111/evo.12075 · Cited by 211
The Human Condition—A Molecular Approach
Pääbo, S. (2014) · Cell · doi:10.1016/j.cell.2013.12.036 · Cited by 197
A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait
Palla, L., & Dudbridge, F. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.06.005 · Cited by 187
Adaptations to Climate-Mediated Selective Pressures in Sheep
Lv, F., Agha, S., Kantanen, J., Colli, L., Stucki, S., Kijas, J., Joost, S., Li, M.-H., & Ajmone‐Marsan, P. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu264 · Cited by 199
Can Population Genetics Adapt to Rapid Evolution?
Messer, P. W., Ellner, S. P., & Hairston, N. G. (2016) · Trends in Genetics · doi:10.1016/j.tig.2016.04.005 · Cited by 193
Prospects and limitations of genomic offset in conservation management
Rellstab, C., Dauphin, B., & Expósito‐Alonso, M. (2021) · Evolutionary Applications · doi:10.1111/eva.13205 · Cited by 204
Modeling Evolution Using the Probability of Fixation: History and Implications
McCandlish, D. M., & Stoltzfus, A. (2014) · The Quarterly Review of Biology · doi:10.1086/677571 · Cited by 187
The Effect of Variation in the Effective Population Size on the Rate of Adaptive Molecular Evolution in Eukaryotes
Gossmann, T. I., Keightley, P. D., & Eyre‐Walker, A. (2012) · Genome Biology and Evolution · doi:10.1093/gbe/evs027 · Cited by 178
Genomic Signature of Adaptation to Climate in Medicago truncatula
Yoder, J. B., Stanton‐Geddes, J., Zhou, P., Briskine, R. V., Young, N. D., & Tiffin, P. (2014) · Genetics · doi:10.1534/genetics.113.159319 · Cited by 173
A practical introduction to Random Forest for genetic association studies in ecology and evolution
Brieuc, M. S. O., Waters, C. D., Drinan, D. P., & Naish, K. A. (2018) · Molecular Ecology Resources · doi:10.1111/1755-0998.12773 · Cited by 179
Detecting Polygenic Evolution: Problems, Pitfalls, and Promises
Wellenreuther, M., & Hansson, B. (2016) · Trends in Genetics · doi:10.1016/j.tig.2015.12.004 · Cited by 159
Life-History Evolution and the Genetics of Fitness Components in Drosophila melanogaster
Flatt, T. (2020) · Genetics · doi:10.1534/genetics.119.300160 · Cited by 174
Fifteen years of genomewide scans for selection: trends, lessons and unaddressed genetic sources of complication
Haasl, R. J., & Payseur, B. A. (2015) · Molecular Ecology · doi:10.1111/mec.13339 · Cited by 164
Predicting Responses to Contemporary Environmental Change Using Evolutionary Response Architectures
Bay, R. A., Rose, N. H., Barrett, R. D. H., Bernatchez, L., Ghalambor, C. K., Lasky, J. R., Brem, R. B., Palumbi, S. R., & Ralph, P. J. (2017) · The American Naturalist · doi:10.1086/691233 · Cited by 156
Natural Selection Affects Multiple Aspects of Genetic Variation at Putatively Neutral Sites across the Human Genome
Lohmueller, K. E., Albrechtsen, A., Li, Y., Kim, S. Y., Korneliussen, T. S., Vinckenbosch, N., Tian, G., Huerta‐Sánchez, E., Feder, A. F., Grarup, N., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002326 · Cited by 155
Population genomics from pool sequencing
Luca Ferretti, A., Ramos-Onsins, S. E., & Miguel Pérez-enciso, A. (2013) · Molecular Ecology · doi:10.1111/mec.12522 · Cited by 154
The transition to modernity and chronic disease: mismatch and natural selection
Corbett, S. J., Courtiol, A., Lummaa, V., Moorad, J. A., & Stearns, S. C. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0012-3 · Cited by 160
Genome‐wide scans detect adaptation to aridity in a widespread forest tree species
Steane, D. A., Potts, B. M., McLean, E. H., Prober, S. M., Stock, W. D., Vaillancourt, R. E., & Byrne, M. M. (2014) · Molecular Ecology · doi:10.1111/mec.12751 · Cited by 156
Polygenic adaptation: From sweeps to subtle frequency shifts
Höllinger, I., Pennings, P. S., & Hermisson, J. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008035 · Cited by 145
On the unfounded enthusiasm for soft selective sweeps
Jensen, J. D. (2014) · Nature Communications · doi:10.1038/ncomms6281 · Cited by 140
Heritability and the evolution of cognitive traits: Table 1
Croston, R., Branch, C. L., Kozlovsky, D. Y., Dukas, R., & Витальевич, П. В. (2015) · Behavioral Ecology · doi:10.1093/beheco/arv088 · Cited by 143
Patterns of Ancestry, Signatures of Natural Selection, and Genetic Association with Stature in Western African Pygmies
Jarvis, J. P., Scheinfeldt, L. B., Soi, S., Lambert, C., Omberg, L., Ferwerda, B., Froment, A., Bodo, J.-M., Beggs, W., Hoffman, G., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002641 · Cited by 139
Parallel adaptive evolution of geographically distant herring populations on both sides of the North Atlantic Ocean
Lamichhaney, S., Fuentes‐Pardo, A. P., Rafati, N., Ryman, N., McCracken, G. R., Bourne, C. M., Singh, R., Ruzzante, D. E., & Andersson, L. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1617728114 · Cited by 138
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J.-A., et al. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.10.009 · Cited by 129
Evaluating genomic data for management of local adaptation in a changing climate: A lodgepole pine case study
Mahony, C. R., MacLachlan, I. R., Lind, B. M., Yoder, J. B., Wang, T., & Aitken, S. N. (2019) · Evolutionary Applications · doi:10.1111/eva.12871 · Cited by 128
Signatures of selection in sheep bred for resistance or susceptibility to gastrointestinal nematodes
McRae, K. M., McEwan, J. C., Dodds, K. G., & Gemmell, N. J. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-637 · Cited by 134
Selection and Adaptation in the Human Genome
Fu, W., & Akey, J. M. (2013) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-091212-153509 · Cited by 130
Local Adaptation in the Flowering-Time Gene Network of Balsam Poplar, Populus balsamifera L.
Keller, S. R., Levsen, N. D., Olson, M. S., & Tiffin, P. (2012) · Molecular Biology and Evolution · doi:10.1093/molbev/mss121 · Cited by 124
Genetic Diversity and the Structure of Genealogies in Rapidly Adapting Populations
Desai, M. M., Walczak, A. M., & Fisher, D. S. (2012) · Genetics · doi:10.1534/genetics.112.147157 · Cited by 115
Detecting polygenic selection in marine populations by combining population genomics and quantitative genetics approaches
Gagnaire, P., & Gaggiotti, O. E. (2016) · Current Zoology · doi:10.1093/cz/zow088 · Cited by 123
Detecting Polygenic Adaptation in Admixture Graphs
Racimo, F., Berg, J. J., & Pickrell, J. K. (2018) · Genetics · doi:10.1534/genetics.117.300489 · Cited by 118
Polygenic adaptation after a sudden change in environment
Hayward, L. K., & Sella, G. (2022) · eLife · doi:10.7554/elife.66697 · Cited by 115
The genomics of local adaptation in trees: are we out of the woods yet?
Lind, B. M., Menon, M., Bolte, C. E., Faske, T. M., & Eckert, A. J. (2018) · Tree Genetics & Genomes · doi:10.1007/s11295-017-1224-y · Cited by 121
Adaptation Mechanisms of Yak (Bos grunniens) to High-Altitude Environmental Stress
Ayalew, W., Chu, M., Liang, C., Wu, X., & Yan, P. (2021) · Animals · doi:10.3390/ani11082344 · Cited by 122
Evolution of polygenic traits under global vs local adaptation
Yeaman, S. (2022) · Genetics · doi:10.1093/genetics/iyab134 · Cited by 114
Vocal learning as a preadaptation for the evolution of human beat perception and synchronization
Patel, A. D. (2021) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2020.0326 · Cited by 113
Adaptation of plasticity to projected maximum temperatures and across climatically defined bioregions
Sandoval‐Castillo, J., Gates, K., Brauer, C. J., Smith, S., Bernatchez, L., & Beheregaray, L. B. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1921124117 · Cited by 111
Local interspecies introgression is the main cause of extreme levels of intraspecific differentiation in mussels
Fraïssé, C., Belkhir, K., Welch, J. J., & Bierne, N. (2015) · Molecular Ecology · doi:10.1111/mec.13299 · Cited by 114
Navigating the Interface Between Landscape Genetics and Landscape Genomics
Storfer, A. T., Patton, A. H., & Fraik, A. K. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00068 · Cited by 112
Disentangling structural genomic and behavioural barriers in a sea of connectivity
Barth, J. M. I., Villegas‐Ríos, D., Freitas, C., Moland, E., Star, B., André, C., Knutsen, H., Bradbury, I., Dierking, J., Petereit, C., et al. (2019) · Molecular Ecology · doi:10.1111/mec.15010 · Cited by 103
Evolution of Anopheles gambiae in Relation to Humans and Malaria
White, B. J., Collins, F. H., & Besansky, N. J. (2011) · Annual Review of Ecology Evolution and Systematics · doi:10.1146/annurev-ecolsys-102710-145028 · Cited by 110
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers
Perry, G. H., Foll, M., Grenier, J.-C., Patin, E., Nédélec, Y., Pacis, A., Barakatt, M., Gravel, S., Zhou, X., Nsobya, S. L., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402875111 · Cited by 105
Environmental adaptation in Chinook salmon ( Oncorhynchus tshawytscha ) throughout their North American range
Hecht, B. C., Matala, A. P., Hess, J. E., & Narum, S. R. (2015) · Molecular Ecology · doi:10.1111/mec.13409 · Cited by 105
Riverscape genomics of a threatened fish across a hydroclimatically heterogeneous river basin
Brauer, C. J., Hammer, M. P., & Beheregaray, L. B. (2016) · Molecular Ecology · doi:10.1111/mec.13830 · Cited by 101
Museum samples reveal rapid evolution by wild honey bees exposed to a novel parasite
Mikheyev, A. S., Tin, M. M. Y., Arora, J., & Seeley, T. D. (2015) · Nature Communications · doi:10.1038/ncomms8991 · Cited by 100
Understanding rare and common diseases in the context of human evolution
Quintana‐Murci, L. (2016) · Genome biology · doi:10.1186/s13059-016-1093-y · Cited by 103
Quantifying the Variation in the Effective Population Size Within a Genome
Gossmann, T. I., Woolfit, M., & Eyre‐Walker, A. (2011) · Genetics · doi:10.1534/genetics.111.132654 · Cited by 99
Evolutionary and food supply implications of ongoing maize domestication by Mexicancampesinos
Bellon, M. R., Mastretta‐Yanes, A., Mendoza, A. P., Ortiz-Santamaría, D., Oliveros‐Galindo, O., Perales, H., Acevedo, F., & Sarukhán, J. (2018) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2018.1049 · Cited by 98
Two extended haplotype blocks are associated with adaptation to high altitude habitats in East African honey bees
Wållberg, A., Schöning, C., Webster, M. T., & Hasselmann, M. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006792 · Cited by 99
An overview of current population genomics methods for the analysis of whole‐genome resequencing data in eukaryotes
Bourgeois, Y., & Warren, B. H. (2021) · Molecular Ecology · doi:10.1111/mec.15989 · Cited by 102
LOST IN THE MAP
Travisano, M., & Shaw, R. G. (2012) · Evolution · doi:10.1111/j.1558-5646.2012.01802.x · Cited by 96
Global genetic differentiation of complex traits shaped by natural selection in humans
Guo, J., Wu, Y., Zhu, Z., Zheng, Z., Trzaskowski, M., Zeng, J., Robinson, M. R., Visscher, P. M., & Yang, J. (2018) · Nature Communications · doi:10.1038/s41467-018-04191-y · Cited by 90
Widespread signatures of positive selection in common risk alleles associated to autism spectrum disorder
Polimanti, R. A., & Gelernter, J. E. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006618 · Cited by 98
Rapid Adaptation of a Polygenic Trait After a Sudden Environmental Shift
Jain, K., & Stephan, W. (2017) · Genetics · doi:10.1534/genetics.116.196972 · Cited by 88
Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade‐off in Mimulus guttatus
Mojica, J. P., Lee, Y. W., Willis, J. H., & Kelly, J. K. (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2012.05662.x · Cited by 90
Population genomics of rapid evolution in natural populations: polygenic selection in response to power station thermal effluents
Dayan, D. I., Du, X., Baris, T. Z., Wagner, D. N., Crawford, D. L., & Oleksiak, M. F. (2019) · BMC Evolutionary Biology · doi:10.1186/s12862-019-1392-5 · Cited by 85
Current Affairs of Microbial Genome-Wide Association Studies: Approaches, Bottlenecks and Analytical Pitfalls
San, J. E., Baichoo, S., Kanzi, A. M., Moosa, Y., Lessells, R. J., Fonseca, V., Mogaka, J., Power, R. A., & de Oliveira, T. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.03119 · Cited by 84
Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila
Rech, G. E., Bogaerts-Márquez, M., Barrón, M. G., Merenciano, M., Villanueva‐Cañas, J. L., Horváth, V., Fiston-Lavier, A.-S., Luyten, I., Venkataram, S., Quesneville, H., et al. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1007900 · Cited by 93
Genome-wide association study reveals the genetic determinism of growth traits in a Gushi-Anka F2 chicken population
Zhang, Y., Wang, Y., Li, Y., Wu, J., Wang, X., Bian, C., Tian, Y., Sun, G., Han, R., Liu, X., et al. (2020) · Heredity · doi:10.1038/s41437-020-00365-x · Cited by 90
From the Past to the Future: Considering the Value and Limits of Evolutionary Prediction
Shaw, R. G. (2018) · The American Naturalist · doi:10.1086/700565 · Cited by 88
Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal
Jeong, C., Witonsky, D., Basnyat, B., Neupane, M., Beall, C. M., Childs, G. H., Craig, S. R., Novembre, J., & Rienzo, A. D. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007650 · Cited by 88
Genomic inbreeding trends, influential sire lines and selection in the global Thoroughbred horse population
McGivney, B. A., Han, H., Corduff, L. R., Katz, L. M., Tozaki, T., MacHugh, D. E., & Hill, E. W. (2020) · Scientific Reports · doi:10.1038/s41598-019-57389-5 · Cited by 90
Genetic variation for adaptive traits is associated with polymorphic inversions in Littorina saxatilis
Koch, E. L., Morales, H. E., Larsson, J., Westram, A. M., Faria, R., Lemmon, A. R., Lemmon, E. M., Johannesson, K., & Butlin, R. K. (2021) · Evolution Letters · doi:10.1002/evl3.227 · Cited by 85
Limited Evidence for Classic Selective Sweeps in African Populations
Granka, J. M., Henn, B. M., Gignoux, C. R., Kidd, J. M., Bustamante, C. D., & Feldman, M. W. (2012) · Genetics · doi:10.1534/genetics.112.144071 · Cited by 81
Selection on a Genetic Polymorphism Counteracts Ecological Speciation in a Stick Insect
Comeault, A. A., Flaxman, S. M., Riesch, R., Curran, E. V., Soria‐Carrasco, V., Gompert, Z., Farkas, T. E., Muschick, M., Parchman, T. L., Schwander, T., et al. (2015) · Current Biology · doi:10.1016/j.cub.2015.05.058 · Cited by 81
The genomic basis of environmental adaptation in house mice
Phifer‐Rixey, M., Bi, K., Ferris, K. G., Sheehan, M. J., Lin, D., Mack, K. L., Keeble, S. M., Suzuki, T. A., Good, J. M., & Nachman, M. W. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007672 · Cited by 80
Adaptations to local environments in modern human populations
Jeong, C., & Di Rienzo, A. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2014.06.011 · Cited by 80
Differentiated demographic histories and local adaptations between Sherpas and Tibetans
Zhang, C., Lü, Y., Feng, Q., Wang, X., Lou, H., Liu, J., Ning, Z., Yuan, K., Wang, Y., Zhou, Y., et al. (2017) · Genome biology · doi:10.1186/s13059-017-1242-y · Cited by 81
Modes of Rapid Polygenic Adaptation
Jain, K., & Stephan, W. (2017) · Molecular Biology and Evolution · doi:10.1093/molbev/msx240 · Cited by 80

Authors: Pritchard, J. K., & Di Rienzo, A.
Affiliations: Howard Hughes Medical Institute (US)
ORCID: Pritchard, Jonathan K.
Venue: Nature Reviews Genetics
Publisher: Springer Science and Business Media LLC
Published: 2010-09-14
Volume: 11
Issue: 10
Pages: 665-667
ISSN: 1471-0056 (ISSN-L)
1471-0064
DOI: 10.1038/nrg2880
PMC: PMC4652788
OpenAlex: W1525285200
Cited by: 445
References: 24
Citations by year: 2026: 16 · 2025: 22 · 2024: 20 · 2023: 16 · 2022: 19 · 2021: 37 · 2020: 43 · 2019: 27 · 2018: 41 · 2017: 36 · 2016: 32 · 2015: 35 · 2014: 30 · 2013: 23 · 2012: 29
FWCI: 2.40
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Nature Reviews Genetics (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Howard Hughes Medical Institute
National Institutes of Health
National Institute of Mental Health (R01MH084703, MH84703)
National Institute of General Medical Sciences (GM79558, R01GM079558)
National Institute of Diabetes and Digestive and Kidney Diseases (DK 56670, R01DK056670)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords: polygenic adaptation, selective sweeps, natural selection, adaptation, quantitative traits
MeSH terms: Adaptation, Physiological, Animals, Genetics, Population, Humans, Selection, Genetic, Evolution, Molecular, Multifactorial Inheritance

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Adaptation–not by sweeps alone

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks