Adult haematopoietic stem cell niches

Cytokine-mediated regulation of CXCR4 expression in human neutrophils

Nagase, H., Miyamasu, M., Yamaguchi, M., Imanishi, M., Tsuno, N. H., Matsushima, K., Yamamoto, K., Morita, Y., & Hirai, K. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.4.711 · Cited by 4,713

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

Méndez‐Ferrer, S., Michurina, T. V., Ferraro, F., Mazloom, A. R., MacArthur, B. D., Lira, S. A., Scadden, D. T., Ma’ayan, A., Enikolopov, G., & Frenette, P. S. (2010) · Nature · doi:10.1038/nature09262 · Cited by 3,381

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

Kiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell · doi:10.1016/j.cell.2005.05.026 · Cited by 3,168

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Ceradini, D. J., Kulkarni, A. R., Callaghan, M. J., Tepper, O. M., Bastidas, N., Kleinman, M. E., Capla, J. M., Galiano, R. D., Levine, J. P., & Gurtner, G. C. (2004) · Nature Medicine · doi:10.1038/nm1075 · Cited by 2,600

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

Zou, Y.-R., Kottmann, A. H., Kuroda, M., Taniuchi, I., & Littman, D. R. (1998) · Nature · doi:10.1038/31269 · Cited by 2,531

The bone marrow niche for haematopoietic stem cells

Morrison, S. J., & Scadden, D. T. (2014) · Nature · doi:10.1038/nature12984 · Cited by 2,451

Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches

Sugiyama, T., Kohara, H., Noda, M., & Nagasawa, T. (2006) · Immunity · doi:10.1016/j.immuni.2006.10.016 · Cited by 2,419

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

Nagasawa, T., Hirota, S., Tachibana, K., Takakura, N., Nishikawa, S.-I., Kitamura, Y., Yoshida, N., Kikutani, H., & Kishimoto, T. (1996) · Nature · doi:10.1038/382635a0 · Cited by 2,338

The relationship between the spleen colony-forming cell and the haemopoietic stem cell.

Schofield, R. (1978) · PubMed · Cited by 2,304

Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment

Sacchetti, B., Funari, A., Michienzi, S., Di Cesare, S., Piersanti, S., Saggio, I., Tagliafico, E., Ferrari, S., Robey, P. G., Riminucci, M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.08.025 · Cited by 2,226

Human splenic TER cells: A relevant prognostic factor acting via the artemin‐GFRα3‐ERK pathway in pancreatic ductal adenocarcinoma

Li, T., Li, H., Zhang, W., Xu, S., Jiang, W., Li, S., Gao, H., Han, X., Xu, H., Wu, C., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.33410 · Cited by 17

The stem cell revolution: on the role of CD164 as a human stem cell marker

Watt, S. M., Bühring, H.-J., Simmons, P. J., & Zannettino, A. C. W. (2021) · npj Regenerative Medicine · doi:10.1038/s41536-021-00143-1 · Cited by 18

Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches

Mesnieres, M., Böhm, A.-M., Peredo, N., Trompet, D., Valle-Tenney, R., Bajaj, M. S., Corthout, N., Nefyodova, E., Cardoen, R., Baatsen, P., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2021.109618 · Cited by 17

The crosstalk between hematopoietic stem cells and their niches

Durand, C., Charbord, P., & Jaffredo, T. (2018) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000438 · Cited by 17

Compartmentalization of the inflammatory response during bacterial sepsis and severe COVID-19

Cavaillon, J., Chousterman, B. G., & Skirecki, T. (2024) · Journal of Intensive Medicine · doi:10.1016/j.jointm.2024.01.001 · Cited by 18

The impact of stem cells in neuro-oncology: applications, evidence, limitations and challenges.

Luzzi, S., Lucifero, A. G., Brambilla, I., Trabatti, C., Mosconi, M., Savasta, S., & Foiadelli, T. (2020) · Acta bio-medica dell'Ateneo parmense/Acta biomedica · doi:10.23750/abm.v91i7-s.9955 · Cited by 17

Inflammation and hematopoietic stem cells aging

He, H., & Wang, J. (2020) · Blood Science · doi:10.1097/bs9.0000000000000063 · Cited by 16

Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis

Lin, Q., Wu, L., Chatla, S., Chowdhury, F. A., Atale, N., Joseph, J., & Du, W. (2022) · Journal of Clinical Investigation · doi:10.1172/jci155914 · Cited by 16

Inhibition of TGF-β signaling in bone marrow endothelial cells promotes hematopoietic recovery in acute myeloid leukemia patients

Wang, Z., Zhang, Z., Lyu, Z., Xing, T., Mi, L., Shen, M.-Z., Li, C., Zhang, X., Chen, D., Wang, Y., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.217290 · Cited by 16

Bone Marrow Endothelial Progenitor Cells remodelling facilitates normal hematopoiesis during Acute Myeloid Leukemia Complete Remission

Xing, T., Hu, L., Zhao, H., Li, C., Wang, Z., Shen, M.-Z., Lyu, Z., Wang, J., Wang, Y., Jiang, H., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-55051-x · Cited by 16

Spatial and biochemical interactions between bone marrow adipose tissue and hematopoietic stem and progenitor cells in rhesus macaques

Robino, J. J., Pamir, N., Rosário, S., Crawford, L. B., Burwitz, B. J., Roberts, C. T., Kurre, P., & Varlamov, O. (2020) · Bone · doi:10.1016/j.bone.2020.115248 · Cited by 16

Murine CXCR3+CXCR6+γδT Cells Reside in the Liver and Provide Protection Against HBV Infection

Wang, Y., Guan, Y., Hu, Y., Li, Y., Lü, N., & Zhang, C. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.757379 · Cited by 16

Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells

Si, S., Nakajima‐Takagi, Y., Iga, T., Tsuji, M., Hou, L., Oshima, M., Koide, S., Saraya, A., Yamazaki, S., Takubo, K., et al. (2018) · Experimental Hematology · doi:10.1016/j.exphem.2018.04.006 · Cited by 16

From skeletal development to the creation of pluripotent stem cell-derived bone-forming progenitors

Tam, W. L., Luyten, F. P., & Roberts, S. J. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0218 · Cited by 15

High-fat diet activates splenic NOD1 and enhances neutrophil recruitment and neutrophil extracellular traps release in the spleen of ApoE-deficient mice

Fernández-García, V., González-Ramos, S., Ortiz, J. A., Martín‐Sanz, P., Gómez‐Coronado, D., Delgado, C., Castrillo, A., & Boscá, L. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04415-x · Cited by 15

Carboxyl-Modified Quantum Dots for NIR-IIb Bone Marrow Imaging

Zhang, P., Wang, Y., Liu, X., Yuan, L., Liu, J., Guo, R., & Tian, Y. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c18282 · Cited by 15

Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis

Luan, Y., Hu, J., Wang, Q., Wang, X., Li, W., Qu, R., Yang, C., Rajendran, B. K., Zhou, H., Liu, P., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113934 · Cited by 15

Megakaryocyte volume modulates bone marrow niche properties and cell migration dynamics

Gorelashvili, M. G., Angay, O., Hemmen, K., Göb, V., Stegner, D., & Heinze, K. G. (2019) · Haematologica · doi:10.3324/haematol.2018.202010 · Cited by 15

Interactions of Hematopoietic Stem Cells with Bone Marrow Niche

Zhao, X., Zhang, C., Cui, X., & Liang, Y. (2020) · Methods in molecular biology · doi:10.1007/7651_2020_298 · Cited by 15

Growth and Differentiation of Circulating Stem Cells After Extensive Ex Vivo Expansion

Barbon, S., Rajendran, S., Bertalot, T., Piccione, M., Gasparella, M., Parnigotto, P. P., Liddo, R. D., & Conconi, M. T. (2021) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-021-00330-7 · Cited by 15

Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice

Durán, J. G. B., Lu, T. M., Houghton, S., Geng, F., Schreiner, R. P., Xiang, J., Rafii, S., Redmond, D., & Lis, R. (2021) · Communications Biology · doi:10.1038/s42003-021-01846-3 · Cited by 15

Human Amniotic Mesenchymal Stromal Cells Support the ex Vivo Expansion of Cord Blood Hematopoietic Stem Cells

Orticelli, V., Papait, A., Vertua, E., Signoroni, P. B., Romele, P., Pietro, L. D., Magatti, M., Teofili, L., Silini, A. R., & Parolini, O. (2021) · Stem Cells Translational Medicine · doi:10.1002/sctm.21-0130 · Cited by 15

Cadmium exposure reprograms energy metabolism of hematopoietic stem cells to promote myelopoiesis at the expense of lymphopoiesis in mice

Zhao, Y., He, J., Zhu, T., Zhang, Y., Zhai, Y., Xue, P., Ye, Y., Zhou, Z., He, M., Qu, W., et al. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.113208 · Cited by 15

Signal improved ultra-fast light-sheet microscope for large tissue imaging

Prince, M. N. H., Garcia, B., Henn, C., Yi, Y., Susaki, E. A., Watakabe, Y., Nemoto, T., Lidke, K. A., Zhao, H., Salinas, I., et al. (2024) · Communications Engineering · doi:10.1038/s44172-024-00205-4 · Cited by 15

Control in dormancy or eradication of cancer stem cells: Mathematical modeling and stability issues

Djema, W., Bonnet, C., Mazenc, F., Clairambault, J., Fridman, E., Hirsch, P., & Delhommeau, F. (2018) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2018.03.038 · Cited by 15

The alliance between nerve fibers and stem cell populations in bone marrow: life partners in sickness and health

Leitão, L., Alves, C. J., Sousa, D. M., Neto, E., Conceição, F., & Lamghari, M. (2019) · The FASEB Journal · doi:10.1096/fj.201900454r · Cited by 16

Isolation, Maintenance and Expansion of Adult Hematopoietic Stem/Progenitor Cells and Leukemic Stem Cells

Mayer, I. M., Hoelbl‐Kovacic, A., Sexl, V., & Doma, E. (2022) · Cancers · doi:10.3390/cancers14071723 · Cited by 18

The Therapeutic Potential of Hematopoietic Stem Cells in Bone Regeneration

Oliveira, C. S., Carreira, M., Correia, C. R., & Mano, J. F. (2022) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2021.0019 · Cited by 14

Endothelial Cell Insulin Signaling Regulates CXCR4 (C-X-C Motif Chemokine Receptor 4) and Limits Leukocyte Adhesion to Endothelium

Rathjen, T., Kunkemoeller, B. H., Cederquist, C., Wang, X., Lockhart, S. M., Patti, J. C., Willenbrock, H., Olsen, G. S., Povlsen, G. K., Beck, H. C., et al. (2022) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.122.317476 · Cited by 15

Targeting Leukemia-Initiating Cells and Leukemic Niches: The Next Therapy Station for T-Cell Acute Lymphoblastic Leukemia?

Zhang, Z., Yang, K., & Zhang, H. (2022) · Cancers · doi:10.3390/cancers14225655 · Cited by 16

Bone marrow-derived extracellular vesicles carry the TGF-β signal transducer Smad2 to preserve hematopoietic stem cells in mice

Gautheron, F., Georgievski, A., Garrido, C., & Quéré, R. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01414-0 · Cited by 14

New advances in the role of JAK2 V617F mutation in myeloproliferative neoplasms

Zhang, Y., Zhao, Y., Liu, Y., Zhang, M., & Zhang, J. (2024) · Cancer · doi:10.1002/cncr.35559 · Cited by 15

Immunoregulation role of the erythroid cells

Niu, C., & Zhang, J. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1466669 · Cited by 14

Magnetic labeling of physically tunable hydrogel-induced mesenchymal stem cell spheroids with IONPs for MRI tracking and bone regeneration

Yan, J., Chen, H., Pan, Y., Yan, Y., Tang, S., Zhou, Q., Hu, K., Guo, Z., Gu, N., & Zhang, F. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102620 · Cited by 14

Hypercholesterolemia Accelerates the Aging Phenotypes of Hematopoietic Stem Cells by a Tet1-Dependent Pathway

Tie, G., Yan, J., Khair, L., Tutto, A. A., & Messina, L. M. (2020) · Scientific Reports · doi:10.1038/s41598-020-60403-w · Cited by 14

Epithelial-mesenchymal transition in haematopoietic stem cell development and homeostasis

Hamidi, S., & Sheng, G. (2018) · The Journal of Biochemistry · doi:10.1093/jb/mvy063 · Cited by 14

Kupffer Cells Promote the Differentiation of Adult Liver Hematopoietic Stem and Progenitor Cells into Lymphocytes via ICAM-1 and LFA-1 Interaction

Meng, D., Qin, Y., Lü, N., Fang, K., Hu, Y., Tian, Z., & Zhang, C. (2019) · Stem Cells International · doi:10.1155/2019/4848279 · Cited by 14

Multilevel defects in the hematopoietic niche in essential thrombocythemia

Sun, T., Ju, M., Dai, X., Dong, H., Gu, W., Gao, Y., Fu, R., Liu, X., Huang, Y., Liu, W., et al. (2019) · Haematologica · doi:10.3324/haematol.2018.213686 · Cited by 14

Daily Ethanol Drinking Followed by an Abstinence Period Impairs Bone Marrow Niche and Mitochondrial Function of Hematopoietic Stem/Progenitor Cells in Rhesus Macaques

Varlamov, O., Bucher, M., Myatt, L., Newman, N., & Grant, K. A. (2020) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14328 · Cited by 14

The Use of Microfabrication Techniques for the Design and Manufacture of Artificial Stem Cell Microenvironments for Tissue Regeneration

Ramos‐Rodriguez, D. H., MacNeil, S., Claeyssens, F., & Asencio, Í. O. (2021) · Bioengineering · doi:10.3390/bioengineering8050050 · Cited by 14

Spleen granulopoiesis in psoriasis immune microenvironment aggravates psoriasis via IL-6/P-STAT3 signaling

Shi, F., Gong, P., Huang, S., Zhu, W., Shi, C., Qi, C., Lei, Z., & Ding, Y. (2025) · Biology Direct · doi:10.1186/s13062-025-00675-2 · Cited by 13

Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer

Easwaran, H., & Weeraratna, A. T. (2025) · Nature reviews. Cancer · doi:10.1038/s41568-025-00868-x · Cited by 15

Inhibiting ferroptosis enhances ex vivo expansion of human haematopoietic stem cells

della Volpe, L., Lee, A., Antoszewski, M., Deik, A., Safina, K. R., Gao, T., Guo, C., Ye, T., Lyu, P., Martin-Rufino, J. D., et al. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01814-7 · Cited by 15

Quo Vadis? Immunodynamics of Myeloid Cells after Myocardial Infarction

Moggio, A., Schunkert, H., Kessler, T., & Sager, H. B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415814 · Cited by 15

Building bones for blood and beyond: the growing field of bone marrow niche model development

Doherty-Boyd, W. S., Donnelly, H., Tsimbouri, M. P., & Dalby, M. J. (2024) · Experimental Hematology · doi:10.1016/j.exphem.2024.104232 · Cited by 13

An Overview of Different Strategies to Recreate the Physiological Environment in Experimental Erythropoiesis

Deleschaux, C., Moras, M., Lefevre, S. D., & Ostuni, M. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155263 · Cited by 13

Niche Regulation of Hematopoiesis: The Environment Is “Micro,” but the Influence Is Large

Rasheed, A. (2022) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.121.316235 · Cited by 14

Skull and vertebral bone marrow in central nervous system inflammation

Ren, H., & Liu, Q. (2023) · Fundamental Research · doi:10.1016/j.fmre.2023.01.012 · Cited by 13

The hematopoietic microenvironment: a network of niches for the development of all blood cell lineages

Hernández-Barrientos, D., Pelayo, R., & Mayani, H. (2023) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiad075 · Cited by 13

The spatiotemporal heterogeneity of the biophysical microenvironment during hematopoietic stem cell development: from embryo to adult

Shi, G., Zhang, P., Zhang, X., Li, J., Zheng, X., Yan, J., Zhang, N., & Yang, H. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03464-8 · Cited by 13

Tracking hematopoietic precursor division ex vivo in real time

Wang, Y., Tian, H., Cai, W., Lian, Z., Bhavanasi, D., Wu, C., Sato, T., Kurokawa, M., Wu, D., Fu, L., et al. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-017-0767-z · Cited by 13

High NESTIN Expression Marks the Endosteal Capillary Network in Human Bone Marrow

Panvini, F. M., Pacini, S., Montali, M., Barachini, S., Mazzoni, S., Morganti, R., Ciancia, E. M., Carnicelli, V., & Petrini, M. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.596452 · Cited by 14

Genomic methylation variations predict the susceptibility of six chemotherapy related adverse effects and cancer development for Chinese colorectal cancer patients

Li, M., Sun, X., Yao, H., Chen, W., Zhang, F., Gao, S., Zou, X., Chen, J., Qiu, S., Wei, H., et al. (2021) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2021.115657 · Cited by 13

Spatiotemporal dynamics of fetal liver hematopoietic niches

Peixoto, M. M., Soares‐da‐Silva, F., Bonnet, V., Zhou, Y., Ronteix, G., Santos, R. F., Mailhé, M.-P., Nogueira, G., Feng, X., Pereira, J. P., et al. (2024) · The Journal of Experimental Medicine · doi:10.1084/jem.20240592 · Cited by 12

Sexual dimorphism in the mouse bone marrow niche regulates hematopoietic engraftment via sex-specific Kdm5c/Cxcl12 signaling

Cui, X., Hou, L., Yan, B., Liu, J., Zhang, C., Sui, P., Tong, S., Luchsinger, L. L., Mendelson, A., Zhou, D., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci182125 · Cited by 13

Notch in the niche: new insights into the role of Notch signaling in the bone marrow

Vanderbeck, A., & Maillard, I. P. (2019) · Haematologica · doi:10.3324/haematol.2019.230854 · Cited by 12

Cytochrome P4501B1 in bone marrow is co-expressed with key markers of mesenchymal stem cells. BMS2 cell line models PAH disruption of bone marrow niche development functions

Larsen, M. C., Almeldin, A., Tong, T., Rondelli, C. M., Maguire, M., Jaskula‐Sztul, R., & Jefcoate, C. R. E. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115111 · Cited by 13

Irradiation pelvienne et toxicité hématopoïétique : revue de la littérature

Kuntz, L., & Noël, G. (2021) · Cancer/Radiothérapie · doi:10.1016/j.canrad.2020.05.018 · Cited by 12

ALKBH3 is dispensable in maintaining hematopoietic stem cells but forced ALKBH3 rectified the differentiation skewing of aged hematopoietic stem cells

He, H., Wang, Y., & Wang, J. (2020) · Blood Science · doi:10.1097/bs9.0000000000000057 · Cited by 12

Nitric Oxide in the Control of the in vitro Proliferation and Differentiation of Human Hematopoietic Stem and Progenitor Cells

Hümmer, J., Kraus, S., Brändle, K., & Lee‐Thedieck, C. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.610369 · Cited by 12

Bone marrow remodeling supports hematopoiesis in response to immune thrombocytopenia progression in mice

Herd, O., Rani, G. F., Hewitson, J. P., Hogg, K., Stone, A. P., Cooper, N., Kent, D. G., Genever, P. G., & Hitchcock, I. S. (2021) · Blood Advances · doi:10.1182/bloodadvances.2020003887 · Cited by 12

Inhibitory effects and molecular mechanisms of ginsenoside Rg1 on the senescence of hematopoietic stem cells

Shang, D., Li, Z., Tan, X., Liu, H., & Tu, Z. (2022) · Fundamental and Clinical Pharmacology · doi:10.1111/fcp.12863 · Cited by 12

Young donor hematopoietic stem cells revitalize aged or damaged bone marrow niche by transdifferentiating into functional niche cells

Yuan, N., Wei, W., Li, J., Qian, J., Jin, Z., Liu, H., Li, X., Li, L., Zhao, C. N., Gao, X., et al. (2023) · Aging Cell · doi:10.1111/acel.13889 · Cited by 13

A review of the role of zinc finger proteins on hematopoiesis

Lima, F. D. S., Gonçalves, C. E. D. S., & Fock, R. A. (2023) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2023.127290 · Cited by 12

Perspective: Biophysical regulation of cancerous and normal blood cell lineages in hematopoietic malignancies

Wong, S. W., Lenzini, S. B., & Shin, J. (2018) · APL Bioengineering · doi:10.1063/1.5025689 · Cited by 12

Cell-based immunomodulatory therapy approaches for type 1 diabetes mellitus

Black, L. A., & Zorina, T. D. (2019) · Drug Discovery Today · doi:10.1016/j.drudis.2019.11.016 · Cited by 12

Blocking the GITR-GITRL pathway to overcome resistance to therapy in sarcomatoid malignant pleural mesothelioma

Chan, M., Wu, L., Yun, Z., McKee, T. D., Cabanero, M., Zhao, Y. D., Kohno, M., Murakami, J., & de Perrot, M. E. (2021) · Communications Biology · doi:10.1038/s42003-021-02430-5 · Cited by 12

Multidimensional Single-Cell Analyses in Organ Development and Maintenance

Zhang, Y., & Liu, F. (2019) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.02.006 · Cited by 12

Effects of skeletal unloading on the bone marrow antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice

Rettig, T. A., Nishiyama, N. C., Pecaut, M. J., & Chapes, S. K. (2019) · Life Sciences in Space Research · doi:10.1016/j.lssr.2019.06.001 · Cited by 13

From complexity to clarity: aging bone marrow niche in bone and blood regeneration and malignancy

Roy, N., Liu, H., Horenberg, A. L., Pathak, A. P., Chen, J., Ramasamy, S. K., Cohen-Solal, M. E., Bözec, A., Grayson, W. L., & Kusumbe, A. P. (2026) · Bone Research · doi:10.1038/s41413-026-00543-3 · Cited by 11

Recent advances in engineering hydrogels for niche biomimicking and hematopoietic stem cell culturing

Huang, X., Wang, Y., Wang, T., Wen, F., Liu, S., & Oudeng, G. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1049965 · Cited by 11

Dormancy in the Tumor Microenvironment

Omokehinde, T., & Johnson, R. W. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-73119-9_2 · Cited by 11

Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of myelodysplastic syndromes and de novo acute myeloid leukemia

Roux, B., Picou, F., Debeissat, C., Koubi, M., Gallay, N., Hirsch, P., Ravalet, N., Béné, M. C., Maigre, M., Hunault, M., et al. (2022) · Cancer Gene Therapy · doi:10.1038/s41417-022-00441-w · Cited by 12

Hypoxia Regulates the Self-Renewal of Endometrial Mesenchymal Stromal/Stem-like Cells via Notch Signaling

Zhang, S., Chan, R., Ng, E. H. Y., & Yeung, W. S. B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094613 · Cited by 11

Clinical Progress and Preclinical Insights Into Umbilical Cord Blood Transplantation Improvement

Sun, Z., Yao, B., Xie, H., & Su, X. (2022) · Stem Cells Translational Medicine · doi:10.1093/stcltm/szac056 · Cited by 11

Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long‐term hematopoiesis

Imai, T., Tanaka, H., Hamazaki, Y., & Minato, N. (2019) · Cancer Science · doi:10.1111/cas.13974 · Cited by 11

Lead Impairs the Development of Innate Lymphoid Cells by Impeding the Differentiation of Their Progenitors

Zhu, T., Zhao, Y., Zhang, P., Shao, Y., He, J., Xue, P., Zheng, W., Qu, W., Jia, X., Zhou, Z., et al. (2020) · Toxicological Sciences · doi:10.1093/toxsci/kfaa074 · Cited by 11

Recellularization of decellularized cancellous bone scaffolds using low-temperature cell seeding

Nakamura, N., Saito, K., Kimura, T., & Kishida, A. (2020) · Tissue and Cell · doi:10.1016/j.tice.2020.101385 · Cited by 11

A radiomics approach for predicting acute hematologic toxicity in patients with cervical or endometrial cancer undergoing external-beam radiotherapy

Le, Z., Wu, D., Chen, X., Wang, L., Xu, Y., Zhao, G., Zhang, C., Chen, Y., Hu, Y., Yao, S., et al. (2023) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2023.109489 · Cited by 10

Deciphering the differential impact of thrombopoietin/MPL signaling on hematopoietic stem/progenitor cell function in bone marrow and spleen

Lee, S., & Zhan, H. (2024) · Stem Cell Reports · doi:10.1016/j.stemcr.2023.12.004 · Cited by 10

The evolving hematopoietic niche during development

Sánchez‐Lanzas, R., Jiménez‐Pompa, A., & Ganuza, M. (2024) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2024.1488199 · Cited by 12

Latexin and hematopoiesis

Zhang, C., & Liang, Y. (2018) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000428 · Cited by 10

Paracrine Factors Released by Osteoblasts Provide Strong Platelet Engraftment Properties

Abu‐Khader, A., Law, K., Jahan, S., Manesia, J. K., Pasha, R. P. K., Hovey, O. F. J., & Pineault, N. (2018) · Stem Cells · doi:10.1002/stem.2956 · Cited by 10

Microfluidic Cell Trap Arrays for Single Hematopoietic Stem/Progenitor Cell Behavior Analysis

Han, X., Ma, Y., Zhang, K., Zhang, P., Shao, N., & Qin, L. (2019) · PROTEOMICS · doi:10.1002/pmic.201900223 · Cited by 10

Centromere assembly and non-random sister chromatid segregation in stem cells

Carty, B. L., & Dunleavy, E. M. (2020) · Essays in Biochemistry · doi:10.1042/ebc20190066 · Cited by 10

Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche

Kato, Y., Hou, L.-B., Miyagi, S., Nitta, E., Aoyama, K., Shinoda, D., Yamazaki, S., Kuribayashi, W., Isshiki, Y., Koide, S., et al. (2019) · Experimental Hematology · doi:10.1016/j.exphem.2019.07.006 · Cited by 10

Protocol for the analysis of hematopoietic lineages in the whole kidney marrow of adult zebrafish

Mahony, C. B., & Monteiro, R. M. (2024) · STAR Protocols · doi:10.1016/j.xpro.2023.102810 · Cited by 9

Acute malaria suppresses the B lymphocytic niche in the bone marrow through the alteration of CXCL12-abundant reticular cells

Lee, M. S. J., Matsuo-Dapaah, J., Zorrilla, C. D. R., Omatsu, Y., Nagasawa, T., Uemura, S., Iwama, A., Ishii, K. J., & Coban, C. (2024) · International Immunology · doi:10.1093/intimm/dxae012 · Cited by 10

Cxcl10 and Cxcr3 regulate self-renewal and differentiation of hematopoietic stem cells

Liu, F., Sun, X., Deng, S., Wu, Y., Liu, X., Wu, C., Huang, K., Li, Y., Dong, Z., Xiao, W., et al. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-03861-7 · Cited by 9

Immune microenvironment of cancer bone metastasis

Hiraga, T. (2024) · Bone · doi:10.1016/j.bone.2024.117328 · Cited by 9

Single-cell profiling unveils a geroprotective role of Procyanidin C1 in hematopoietic immune system via senolytic and senomorphic effects

Liu, X., Liu, Y., Gao, Y., Zhang, C., Gu, C., Lv, J., Wu, J., & Su, W. (2025) · npj Aging · doi:10.1038/s41514-025-00222-3 · Cited by 9

Intra-bone marrow diversity of endothelial cells and its impact on hematopoietic stem cell development and maintenance

Shimizu, S., & Kubota, Y. (2025) · Experimental Hematology · doi:10.1016/j.exphem.2025.104817 · Cited by 10

Haematopoietic stem cell number is not solely defined by niche availability

Takeishi, S., Marchand, T., Koba, W. R., Borger, D. K., Xu, C., Guha, C., Bergman, A., Frenette, P. S., Gritsman, K., & Steidl, U. G. (2025) · Nature · doi:10.1038/s41586-025-09462-5 · Cited by 9

Mineral and Amino Acid Profiling of Different Hematopoietic Populations from the Mouse Bone Marrow

Girotra, M., Monnard, C., Konz, T., Sizzano, F., Goulet, L., Godin, J., Coukos, G., Rezzi, S., & Vannini, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176444 · Cited by 9

Monoclonal Gammopathies and the Bone Marrow Microenvironment: From Bench to Bedside and Then Back Again

Plano, F., Corsale, A. M., Gigliotta, E., Camarda, G. M., Vullo, C., Simone, M. D., Azgomi, M. S., Speciale, M., Carlisi, M., Caccamo, N., et al. (2023) · Hematology Reports · doi:10.3390/hematolrep15010004 · Cited by 11

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells

Matsuoka, S., Facchini, R., Luis, T. C., Carrelha, J., Woll, P. S., Mizukami, T., Wu, B., Boukarabila, H., Buono, M., Norfo, R., et al. (2023) · Blood · doi:10.1182/blood.2022019018 · Cited by 9

Zinc and aging: a narrative review of the effects on hematopoiesis and its link with diseases

Lima, F. D. S., Gonçalves, C. E. D. S., & Fock, R. A. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuad115 · Cited by 11

CoCl 2 ‐Induced hypoxia promotes hPDLSCs osteogenic differentiation through AKT/mTOR/4EBP‐1/HIF‐1α signaling and facilitates the repair of alveolar bone defects

Fan, Z., Liu, Y., Lan, Y., Wu, Y., Li, J., & Xu, X. (2024) · Cell Biology International · doi:10.1002/cbin.12148 · Cited by 9

Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis

Liu, X., Montemurro, M., Vanzo, N. F., & Crozatier, M. (2025) · Nature Communications · doi:10.1038/s41467-025-60493-y · Cited by 9

Chemical modulation of cell fates: in situ regeneration

Qin, H., Zhao, A., & Fu, X. (2018) · Science China Life Sciences · doi:10.1007/s11427-018-9349-5 · Cited by 9

Niches that regulate stem cells and hematopoiesis in adult bone marrow

Comazzetto, S., Shen, B., & Morrison, S. J. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.05.018 · Cited by 312

Uncertainty in the niches that maintain haematopoietic stem cells

Kiel, M. J., & Morrison, S. J. (2008) · Nature reviews. Immunology · doi:10.1038/nri2279 · Cited by 608

Hematopoietic stem cell niches

Cheng, H., & Cheng, T. (2017) · Scientia Sinica Vitae · doi:10.1360/n052017-00273 · Cited by 3

Hierarchy of immature hematopoietic cells related to blood flow and niche

Lévesque, J.-P., & Winkler, I. G. (2011) · Current Opinion in Hematology · doi:10.1097/moh.0b013e3283475fe7 · Cited by 56

Haematopoietic stem cell activity and interactions with the niche

Pinho, S., & Frenette, P. S. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0103-9 · Cited by 1,064