Adult haematopoietic stem cell niches

Cytokine-mediated regulation of CXCR4 expression in human neutrophils

Nagase, H., Miyamasu, M., Yamaguchi, M., Imanishi, M., Tsuno, N. H., Matsushima, K., Yamamoto, K., Morita, Y., & Hirai, K. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.4.711 · Cited by 4,713

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

Méndez‐Ferrer, S., Michurina, T. V., Ferraro, F., Mazloom, A. R., MacArthur, B. D., Lira, S. A., Scadden, D. T., Ma’ayan, A., Enikolopov, G., & Frenette, P. S. (2010) · Nature · doi:10.1038/nature09262 · Cited by 3,381

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

Kiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell · doi:10.1016/j.cell.2005.05.026 · Cited by 3,168

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Ceradini, D. J., Kulkarni, A. R., Callaghan, M. J., Tepper, O. M., Bastidas, N., Kleinman, M. E., Capla, J. M., Galiano, R. D., Levine, J. P., & Gurtner, G. C. (2004) · Nature Medicine · doi:10.1038/nm1075 · Cited by 2,600

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

Zou, Y.-R., Kottmann, A. H., Kuroda, M., Taniuchi, I., & Littman, D. R. (1998) · Nature · doi:10.1038/31269 · Cited by 2,531

The bone marrow niche for haematopoietic stem cells

Morrison, S. J., & Scadden, D. T. (2014) · Nature · doi:10.1038/nature12984 · Cited by 2,451

Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches

Sugiyama, T., Kohara, H., Noda, M., & Nagasawa, T. (2006) · Immunity · doi:10.1016/j.immuni.2006.10.016 · Cited by 2,419

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

Nagasawa, T., Hirota, S., Tachibana, K., Takakura, N., Nishikawa, S.-I., Kitamura, Y., Yoshida, N., Kikutani, H., & Kishimoto, T. (1996) · Nature · doi:10.1038/382635a0 · Cited by 2,338

The relationship between the spleen colony-forming cell and the haemopoietic stem cell.

Schofield, R. (1978) · PubMed · Cited by 2,304

Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment

Sacchetti, B., Funari, A., Michienzi, S., Di Cesare, S., Piersanti, S., Saggio, I., Tagliafico, E., Ferrari, S., Robey, P. G., Riminucci, M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.08.025 · Cited by 2,226

Organoids

Zhao, Z., Chen, X., Dowbaj, A. M., Sljukic, A., Bratlie, K., Lin, L., Fong, E. L. S., Balachander, G. M., Chen, Z., Soragni, A., et al. (2022) · Nature Reviews Methods Primers · doi:10.1038/s43586-022-00174-y · Cited by 1,082

The bone marrow microenvironment at single-cell resolution

Tikhonova, A. N., Dolgalev, I., Hu, H., Sivaraj, K. K., Hoxha, E., Cuesta-Domínguez, Á., Pinho, S., Akhmetzyanova, I., Gao, J., Witkowski, M., et al. (2019) · Nature · doi:10.1038/s41586-019-1104-8 · Cited by 936

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation

Buenrostro, J. D., Corces, M. R., Lareau, C. A., Wu, B., Schep, A. N., Aryee, M. J., Majeti, R., Chang, H. Y., & Greenleaf, W. J. (2018) · Cell · doi:10.1016/j.cell.2018.03.074 · Cited by 670

Anatomical, Physiological, and Functional Diversity of Adipose Tissue

Zwick, R. K., Guerrero‐Juarez, C. F., Horsley, V., & Plikus, M. V. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2017.12.002 · Cited by 562

Menstruation: science and society

Critchley, H., Babayev, E., Bulun, S. E., Clark, S., Garcia-Grau, I., Gregersen, P. K., Kilcoyne, A., Kim, J.-Y. J., Lavender, M. D., Marsh, E. E., et al. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.06.004 · Cited by 533

Niches for Hematopoietic Stem Cells and Their Progeny

Wei, Q., & Frenette, P. S. (2018) · Immunity · doi:10.1016/j.immuni.2018.03.024 · Cited by 398

Causes and Consequences of Hematopoietic Stem Cell Heterogeneity

Haas, S. F., Trumpp, A., & Milsom, M. D. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.04.003 · Cited by 362

A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis

Shen, B., Tasdogan, A., Ubellacker, J. M., Zhang, J., Nosyreva, E. D., Du, L., Murphy, M. M., Hu, S., Yi, Y., Kara, N., et al. (2021) · Nature · doi:10.1038/s41586-021-03298-5 · Cited by 310

Niches that regulate stem cells and hematopoiesis in adult bone marrow

Comazzetto, S., Shen, B., & Morrison, S. J. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.05.018 · Cited by 312

New paradigms on hematopoietic stem cell differentiation

Cheng, H., Zheng, Z., & Cheng, T. (2019) · Protein & Cell · doi:10.1007/s13238-019-0633-0 · Cited by 350

The Role of Tumor Microenvironment in Multiple Myeloma Development and Progression

García-Ortiz, A., Rodríguez-García, Y., Encinas, J., Maroto-Martín, E., Castellano, E., Teixidó, J., & Martínez-López, J. (2021) · Cancers · doi:10.3390/cancers13020217 · Cited by 238

Leukaemia: a model metastatic disease

Whiteley, A. E., Price, T. T., Cantelli, G., & Sipkins, D. A. (2021) · Nature reviews. Cancer · doi:10.1038/s41568-021-00355-z · Cited by 241

Haematopoietic stem cell self-renewal in vivo and ex vivo

Wilkinson, A. C., Igarashi, K. J., & Nakauchi, H. (2020) · Nature Reviews Genetics · doi:10.1038/s41576-020-0241-0 · Cited by 226

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

Chakraborty, T., Driscoll, M., Jeffery, E. C., Murphy, M. M., Roudot, P., Chang, B.-J., Vora, S., Wong, W. M., Nielson, C. D., Zhang, H., et al. (2019) · Nature Methods · doi:10.1038/s41592-019-0615-4 · Cited by 187

Hematopoiesis and Cardiovascular Disease

Poller, W. C., Nahrendorf, M., & Świrski, F. K. (2020) · Circulation Research · doi:10.1161/circresaha.120.315895 · Cited by 191

Maintaining homeostatic control of periodontal bone tissue

Hathaway‐Schrader, J. D., & Novince, C. M. (2021) · Periodontology 2000 · doi:10.1111/prd.12368 · Cited by 174

Quantitative spatial analysis of haematopoiesis-regulating stromal cells in the bone marrow microenvironment by 3D microscopy

Gomariz, Á., Helbling, P. M., Isringhausen, S., Suessbier, U., Becker, A. S., Boss, A., Nagasawa, T., Paul, G., Göksel, O., Székely, G. J., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04770-z · Cited by 170

Hematopoietic Hierarchy – An Updated Roadmap

Zhang, Y., Gao, S., Xia, J., & Liu, F. (2018) · Trends in Cell Biology · doi:10.1016/j.tcb.2018.06.001 · Cited by 203

Metabolic coordination of cell fate by α-ketoglutarate-dependent dioxygenases

Baksh, S. C., & Finley, L. W. S. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2020.09.010 · Cited by 165

Unraveling Hematopoiesis through the Lens of Genomics

Liggett, L. A., & Sankaran, V. G. (2020) · Cell · doi:10.1016/j.cell.2020.08.030 · Cited by 163

Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis

Kjell, J., Fischer-Sternjak, J., Thompson, A. J., Friess, C., Sticco, M. J., Salinas, F., Cox, J., Martinelli, D. C., Ninkovic, J., Franze, K., et al. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.01.002 · Cited by 163

Engineering Hydrogel Microenvironments to Recapitulate the Stem Cell Niche

Madl, C. M., & Heilshorn, S. C. (2017) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-062117-120954 · Cited by 169

Stem cell quiescence: the challenging path to activation

Urbán, N., & Cheung, T. H. (2021) · Development · doi:10.1242/dev.165084 · Cited by 168

Evolving cancer–niche interactions and therapeutic targets during bone metastasis

Satcher, R. L., & Zhang, X. H.-F. (2021) · Nature reviews. Cancer · doi:10.1038/s41568-021-00406-5 · Cited by 153

N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells

Zhao, M., Tao, F., Venkatraman, A., Li, Z., Smith, S. E., Unruh, J., Chen, S., Ward, C., Qian, P., Perry, J. M., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2018.12.093 · Cited by 146

The Bones of Children With Obesity

Fintini, D., Cianfarani, S., Cofini, M., Andreoletti, A., Ubertini, G., Cappa, M., & Manco, M. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00200 · Cited by 154

Insight into Mechanobiology: How Stem Cells Feel Mechanical Forces and Orchestrate Biological Functions

Argentati, C., Morena, F., Tortorella, I., Bazzucchi, M., Porcellati, S., Emiliani, C., & Martino, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20215337 · Cited by 143

Apelin+ Endothelial Niche Cells Control Hematopoiesis and Mediate Vascular Regeneration after Myeloablative Injury

Chen, Q., Liu, Y., Jeong, H., Stehling, M., Dinh, V. V., Zhou, B., & Adams, R. H. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.10.006 · Cited by 135

Dynamic responses of the haematopoietic stem cell niche to diverse stresses

Batsivari, A., Haltalli, M. L. R., Passaro, D., Pospori, C., Celso, C. L., & Bonnet, D. A. (2020) · Nature Cell Biology · doi:10.1038/s41556-019-0444-9 · Cited by 139

Metabolic regulation of skeletal cell fate and function in physiology and disease

van Gastel, N., & Carmeliet, G. (2021) · Nature Metabolism · doi:10.1038/s42255-020-00321-3 · Cited by 137

Plasma cells are obligate effectors of enhanced myelopoiesis in aging bone marrow

Pioli, P. D., Casero, D., Montecino-Rodriguez, E., Morrison, S. L., & Dorshkind, K. (2019) · Immunity · doi:10.1016/j.immuni.2019.06.006 · Cited by 131

Tumor-on-chip modeling of organ-specific cancer and metastasis

Piccolo, N. D., Shirure, V. S., Bi, Y., Goedegebuure, S. P., Gholami, S., Hughes, C. C. W., Fields, R. C., & George, S. C. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.05.008 · Cited by 134

Evolutionary Parasitology

Schmid‐Hempel, P. (2021) · doi:10.1093/oso/9780198832140.001.0001 · Cited by 137

Complex mammalian-like haematopoietic system found in a colonial chordate

Rosental, B., Kowarsky, M., Seita, J., Corey, D. M., Ishizuka, K. J., Palmeri, K. J., Chen, S.-Y., Sinha, R., Okamoto, J., Mantalas, G. L., et al. (2018) · Nature · doi:10.1038/s41586-018-0783-x · Cited by 128

Macrophages and Cardiovascular Health

Frodermann, V., & Nahrendorf, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00068.2017 · Cited by 128

Advances in understanding the pathogenesis of acquired aplastic anaemia

Luzzatto, L., & Risitano, A. M. (2018) · British Journal of Haematology · doi:10.1111/bjh.15443 · Cited by 124

Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation

Verovskaya, E. V., Dellorusso, P. V., & Passegue, E. A. (2019) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2019.04.006 · Cited by 130

In situ mapping identifies distinct vascular niches for myelopoiesis

Zhang, J., Wu, Q., Johnson, C. B., Pham, G. H., Kinder, J. M., Olsson, A., Slaughter, A., May, M. L., Weinhaus, B., D’Alessandro, A., et al. (2021) · Nature · doi:10.1038/s41586-021-03201-2 · Cited by 131

Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche

Krohn-Grimberghe, M., Mitchell, M. J., Schloss, M. J., Khan, O. F., Courties, G., Guimarães, P. P. G., Rohde, D., Cremer, S., Kowalski, P. S., Sun, Y., et al. (2020) · Nature Biomedical Engineering · doi:10.1038/s41551-020-00623-7 · Cited by 123

Hyperleukocytosis and Leukostasis in Acute Myeloid Leukemia: Can a Better Understanding of the Underlying Molecular Pathophysiology Lead to Novel Treatments?

Bewersdorf, J. P., & Zeidan, A. M. (2020) · Cells · doi:10.3390/cells9102310 · Cited by 117

Inflammatory signaling regulates hematopoietic stem and progenitor cell development and homeostasis

Collins, A., Mitchell, C. A., & Passegué, E. (2021) · Journal of Experimental Medicine · doi:10.1084/jem.20201545 · Cited by 111

The mechanisms of pathological extramedullary hematopoiesis in diseases

Yang, X., Chen, D., Long, H., & Zhu, B. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03450-w · Cited by 114

Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression

Valet, C., Magnen, M., Qiu, L., Cleary, S. J., Wang, K. M., Ranucci, S., Grockowiak, É., Boudra, R., Conrad, C., Seo, Y., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci153920 · Cited by 108

Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis

Yip, R. K. H., Rimes, J. S., Capaldo, B. D., Vaillant, F., Mouchemore, K. A., Pal, B., Chen, Y., Surgenor, E. E., Murphy, A. J., Anderson, R. L., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-26556-6 · Cited by 105

Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

Kruta, M., Sunshine, M. J., Chua, B. A., Fu, Y., Chawla, A., Dillingham, C. H., Hidalgo San Jose, L., De Jong, B., Zhou, F. J., & Signer, R. A. J. (2021) · Cell Stem Cell · doi:10.1016/j.stem.2021.07.009 · Cited by 100

Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones

de Boer, B., Prick, J. C. M., Pruis, M. G. M., Keane, P., Imperato, M. R., Jaques, J., Brouwers-Vos, A. Z., Hogeling, S. M., Woolthuis, C. M., Nijk, M. T., et al. (2018) · Cancer Cell · doi:10.1016/j.ccell.2018.08.014 · Cited by 101

Extramedullary Hematopoiesis of the Liver and Spleen

Cenariu, D., Iluta, S., Zimța, A., Petrushev, B., Qian, L., Dîrzu, N., Tomuleasa, C., Bumbea, H., & Zaharie, F. V. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10245831 · Cited by 105

Click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries

Ruan, H., Li, Y., Wang, C., Jiang, Y., Han, Y., Li, Y., Zheng, D., Ye, J., Chen, G., Yang, G.-Y., et al. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.06.007 · Cited by 95

Bone metastasis: Interaction between cancer cells and bone microenvironment

Hiraga, T. (2019) · Journal of Oral Biosciences · doi:10.1016/j.job.2019.02.002 · Cited by 102

Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease

Rohde, D., Vandoorne, K., Lee, I., Grune, J., Zhang, S., McAlpine, C. S., Schloss, M. J., Nayar, R., Courties, G., Frodermann, V., et al. (2021) · Nature Cardiovascular Research · doi:10.1038/s44161-021-00002-8 · Cited by 100

An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion

Baumgärtner, C., Toifl, S., Farlik, M., Halbritter, F., Scheicher, R., Fischer, I., Sexl, V., Bock, C., & Baccarini, M. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.05.003 · Cited by 99

Stem cell bioengineering: building from stem cell biology

Tewary, M., Shakiba, N., & Zandstra, P. W. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0040-z · Cited by 97

Single‐cell transcriptomics of LepR‐positive skeletal cells reveals heterogeneous stress‐dependent stem and progenitor pools

Mo, C., Guo, J., Qin, J., Zhang, X., Sun, Y., Wei, H., Cao, D., Zhang, Y., Zhao, C., Xiong, Y., et al. (2021) · The EMBO Journal · doi:10.15252/embj.2021108415 · Cited by 95

Splenic stromal niches in homeostasis and immunity

Alexandre, Y. O., & Mueller, S. N. (2023) · Nature reviews. Immunology · doi:10.1038/s41577-023-00857-x · Cited by 90

Cell Response to Mechanical Microenvironment Cues Via Rho Signaling: From Mechanobiology to Mechanomedicine

Xie, N., Xiao, C., Shu, Q., Cheng, B., Wang, Z., Xue, R., Zhang, W., Wang, J., Shi, H., Fan, D., et al. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.01.039 · Cited by 90

Plasma Cells, the Next Generation: Beyond Antibody Secretion

Pioli, P. D. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02768 · Cited by 91

The extracellular matrix of hematopoietic stem cell niches

Lee‐Thedieck, C., Schertl, P., & Klein, G. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114069 · Cited by 96

Myelosuppression Alleviation and Hematopoietic Regeneration by Tetrahedral‐Framework Nucleic‐Acid Nanostructures Functionalized with Osteogenic Growth Peptide

Zhang, T., Zhou, M., Xiao, D., Liu, Z., Jiang, Y., Feng, M., Lin, Y., & Cai, X. (2022) · Advanced Science · doi:10.1002/advs.202202058 · Cited by 87

Deconstructed Microfluidic Bone Marrow On‐A‐Chip to Study Normal and Malignant Hemopoietic Cell–Niche Interactions

Aleman, J., George, S. K., Herberg, S., Devarasetty, M., Porada, C. D., Skardal, A., & Almeida-Porada, G. D. (2019) · Small · doi:10.1002/smll.201902971 · Cited by 86

Generation of Myeloid Cells in Cancer: The Spleen Matters

Wu, C., Hua, Q., & Zheng, L. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01126 · Cited by 89

Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development

Yao, Y., Li, F., Huang, J., Jin, J., & Wang, H. (2021) · Experimental Hematology and Oncology · doi:10.1186/s40164-021-00233-2 · Cited by 93

Multiple faces of succinate beyond metabolism in blood

Grimolizzi, F., & Arranz, L. (2018) · Haematologica · doi:10.3324/haematol.2018.196097 · Cited by 85

Pathogenesis of Acquired Aplastic Anemia and the Role of the Bone Marrow Microenvironment

Medinger, M., Drexler, B., Lengerke, C., & Passweg, J. R. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00587 · Cited by 84

Microtubules control nuclear shape and gene expression during early stages of hematopoietic differentiation

Biedzinski, S., Agsu, G. G., Vianay, B., Delord, M., Blanchoin, L., Larghero, J., Faivre, L., Théry, M., & Brunet, S. (2020) · The EMBO Journal · doi:10.15252/embj.2019103957 · Cited by 91

JAK-STAT in Early Hematopoiesis and Leukemia

Fasouli, E. S., & Katsantoni, E. Z. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.669363 · Cited by 81

Building the Next Generation of Humanized Hemato-Lymphoid System Mice

Martinov, T., McKenna, K. M., Tan, W. H., Collins, E. J., Kehret, A. R., Linton, J. D., Olsen, T. M., Shobaki, N., & Rongvaux, A. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.643852 · Cited by 81

PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Li, J., Kaneda, M. M., Ma, J., Li, M., Shepard, R. M., Patel, K. S., Koga, T., Sarver, A. L., Furnari, F. B., Xu, B., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2009290118 · Cited by 81

The multifaceted role of periostin in priming the tumor microenvironments for tumor progression

Cui, D., Huang, Z., Liu, Y., & Ouyang, G. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2646-2 · Cited by 80

Multiscale engineering of immune cells and lymphoid organs

Kim, S., Shah, S. B., Graney, P. L., & Singh, A. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0100-9 · Cited by 79

Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF

Ramalingam, P., Poulos, M. G., Lazzari, E., Gutkin, M. C., Lopez, D., Kloss, C. C., Crowley, M. J., Katsnelson, L., Freire, A. G., Greenblatt, M. B., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-14478-8 · Cited by 78

Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis

Zhang, Z., Huang, Z., Ong, B., Sahu, C., Zeng, H., & Ruan, H. (2019) · Haematologica · doi:10.3324/haematol.2018.205856 · Cited by 78

DNA Damage-Induced Inflammatory Microenvironment and Adult Stem Cell Response

Cinat, D., Coppes, R. P., & Barazzuol, L. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.729136 · Cited by 79

The bone marrow microenvironment in health and disease at a glance

Kumar, R., Godavarthy, P. S., & Krause, D. S. (2018) · Journal of Cell Science · doi:10.1242/jcs.201707 · Cited by 83

Normal Hematopoiesis Is a Balancing Act of Self-Renewal and RegenerationPreprint

Olson, O. C., Kang, Y.-A., & Passegue, E. A. (2020) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a035519 · Cited by 89

IL-6 blockade reverses bone marrow failure induced by human acute myeloid leukemia

Zhang, T. Y., Dutta, R., Benard, B. A., Zhao, F., Yin, R. R., & Majeti, R. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aax5104 · Cited by 77

Mechanisms of extramedullary relapse in acute lymphoblastic leukemia: Reconciling biological concepts and clinical issues

Rouger, J., Jakobczyk, H., Debaize, L., Cousin, É., Galibert, M., Troadec, M., & Gandemer, V. (2019) · Blood Reviews · doi:10.1016/j.blre.2019.04.003 · Cited by 76

Bone marrow niches in the regulation of bone metastasis

Chen, F., Han, Y., & Kang, Y. (2021) · British Journal of Cancer · doi:10.1038/s41416-021-01329-6 · Cited by 77

Intravital Imaging Reveals Motility of Adult Hematopoietic Stem Cells in the Bone Marrow Niche

Upadhaya, S., Krichevsky, O., Akhmetzyanova, I., Sawai, C. M., Fooksman, D., & Reizis, B. (2020) · Cell stem cell · doi:10.1016/j.stem.2020.06.003 · Cited by 74

Niches for Skeletal Stem Cells of Mesenchymal Origin

Kurenkova, A. D., Medvedeva, E. V., Newton, P. T., & Chagin, A. S. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00592 · Cited by 74

Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates

Martı́nez, P., Ballarin, L., Ereskovsky, A. V., Gazave, E., Hobmayer, B., Manni, L., Röttinger, É., Sprecher, S. G., Tiozzo, S., Coelho, A. V., et al. (2022) · BMC Biology · doi:10.1186/s12915-022-01230-5 · Cited by 73

Bone as a Preferential Site for Metastasis

Sowder, M. E., & Johnson, R. W. (2018) · JBMR Plus · doi:10.1002/jbm4.10126 · Cited by 75

Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition

Galipeau, J., Krampera, M., LeBlanc, K., Nolta, J. A., Phinney, D. G., Shi, Y., Tarte, K., Viswanathan, S., & Martín, I. (2021) · Cytotherapy · doi:10.1016/j.jcyt.2020.11.007 · Cited by 71

Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil

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Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal

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