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Studying the mononuclear phagocyte system in the molecular age

Chow, Andrew, Brown, Brian D., Merad, Miriam·2011·Nature Reviews Immunology
DOI 10.1038/nri3087
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Abstract

The mononuclear phagocyte system (MPS) comprises monocytes, macrophages and dendritic cells. Tissue phagocytes share several cell surface markers, phagocytic capability and myeloid classification; however, the factors that regulate the differentiation, homeostasis and function of macrophages and dendritic cells remain largely unknown. The purpose of this manuscript is to review the tools that are currently available and those that are under development to study the origin and function of mononuclear phagocytes.

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Metadata

Authors
Chow, A., Brown, B. D., & Merad, M.
Venue
Nature Reviews Immunology
Publisher
Springer Science and Business Media LLC
Published
2011-10-25
Volume
11
Issue
11
Pages
788-798
ISSN
  • 1474-1733
  • 1474-1741
DOI
10.1038/nri3087
Cited by
279
References
17
Language
en
Licence
www.springer.com/tdm (tdm)

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