Advancing host-directed therapy for tuberculosis

Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response

Liu, P. T., Stenger, S., Li, H., Wenzel, L., Tan, B. H., Krutzik, S. R., Ochoa, M. T., Schauber, J., Wu, K., Meinken, C., et al. (2006) · Science · doi:10.1126/science.1123933 · Cited by 3,924 · see citing works

Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent

Keane, J., Gershon, S. K., Wise, R. P., Mirabile‐Levens, E., Kasznica, J. M., Schwieterman, W. D., Siegel, J. N., & Braun, M. M. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011110 · Cited by 3,683 · see citing works

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Egan, D. F., Shackelford, D. B., Mihaylova, M. M., Gelino, S., Kohnz, R. A., Mair, W., Vasquez, D. S., Joshi, A., Gwinn, D. M., Taylor, R., et al. (2011) · Science · doi:10.1126/science.1196371 · Cited by 2,600 · see citing works

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Ravikumar, B., Vacher, C., Berger, Z., Davies, J. E., Luo, S., Oroz, L. G., Scaravilli, F., Easton, D. F., Duden, R., O'Kane, C. J., et al. (2004) · Nature Genetics · doi:10.1038/ng1362 · Cited by 2,347 · see citing works

Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

Gutierrez, M. G., Master, S. S., Singh, S. B., Taylor, G. A., Colombo, M. I., & Deretic, V. (2004) · Cell · doi:10.1016/j.cell.2004.11.038 · Cited by 2,252 · see citing works

Identification of a Primary Target of Thalidomide Teratogenicity

Ito, T., Ando, H., Suzuki, T., Ogura, T., Hotta, K., Imamura, Y., Yamaguchi, Y., & Handa, H. (2010) · Science · doi:10.1126/science.1177319 · Cited by 2,136 · see citing works

The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins

Lu, G., Middleton, R. E., Sun, H., Naniong, M., Ott, C. J., Mitsiades, C. S., Wong, K.-K., Bradner, J. E., & Kaelin, W. G. (2014) · Science · doi:10.1126/science.1244917 · Cited by 1,583 · see citing works

A Mutation in the Interferon-γ –Receptor Gene and Susceptibility to Mycobacterial Infection

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Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

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Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti–tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: A randomized, placebo‐controlled, 52‐week trial

Keystone, E. C., Kavanaugh, A. F., Sharp, J. T., Tannenbaum, H., Hua, Y., Teoh, L. S., Fischkoff, S. A., & Chartash, E. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20217 · Cited by 1,174 · see citing works

Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial

Sandborn, W. J., Hanauer, S. B., Katz, S., Safdi, M. A., Wolf, D. G., Baerg, R. D., Tremaine, W. J., Johnson, T., Diehl, N. N., & ZINSMEISTER, A. R. (2001) · Gastroenterology · doi:10.1053/gast.2001.28674 · Cited by 906 · see citing works

Identification of a candidate therapeutic autophagy-inducing peptide

Shoji-Kawata, S., Sumpter, R., Leveno, M., Campbell, G. R., Zou, Z., Kinch, L., Wilkins, A. D., Sun, Q., Pallauf, K., MacDuff, D., et al. (2013) · Nature · doi:10.1038/nature11866 · Cited by 760 · see citing works

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

Mayer-Barber, K. D., Andrade, B. B., Oland, S. D., Amaral, E. P., Barber, D. L., Gonzales, J., Derrick, S. C., Shi, R., Kumar, N. P., Wei, W., et al. (2014) · Nature · doi:10.1038/nature13489 · Cited by 757 · see citing works

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

Watson, R. O., Manzanillo, P. S., & Cox, J. S. (2012) · Cell · doi:10.1016/j.cell.2012.06.040 · Cited by 755 · see citing works

Timing of Initiation of Antiretroviral Drugs during Tuberculosis Therapy

Karim, S. S. A., Naidoo, K., Grobler, A. C., Padayatchi, N., Baxter, C., Gray, A., Gengiah, T. N., Nair, G., Bamber, S., Singh, A., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0905848 · Cited by 662 · see citing works

Effectiveness of recommendations to prevent reactivation of latent tuberculosis infection in patients treated with tumor necrosis factor antagonists

Carmona, L., Gómez-Reino, J. J., Rodrı́guez-Valverde, V., Montero, D., Pascual, E., Mola, E. M., Carreño, L., Figueroa, M., & BIOBADASER Group (2005) · Arthritis & Rheumatism · doi:10.1002/art.21043 · Cited by 655 · see citing works

Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis

Gillespie, S. H., Crook, A. M., McHugh, T. D., Mendel, C. M., Meredith, S. K., Murray, S. R., Pappas, F., Phillips, P. P. J., & Nunn, A. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1407426 · Cited by 644 · see citing works

Risk of tuberculosis is higher with anti–tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: The three‐year prospective french research axed on tolerance of biotherapies registry

Tubach, F., Salmon, D., Ravaud, P., Allanore, Y., Goupille, P., Bréban, M., Pallot‐Prades, B., Pouplin, S., Sacchi, A., Chichemanian, R.-M., et al. (2009) · Arthritis & Rheumatism · doi:10.1002/art.24632 · Cited by 629 · see citing works

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

Gao, P., Ascano, M., Zillinger, T., Wang, W., Dai, P., Serganov, A. A., Gaffney, B. L., Shuman, S., Jones, R. A., Deng, L., et al. (2013) · Cell · doi:10.1016/j.cell.2013.07.023 · Cited by 595 · see citing works

Relationship of the Manifestations of Tuberculosis to CD4 Cell Counts in Patients with Human Immunodeficiency Virus Infection

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High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

Martineau, A. R., Timms, P. M., Bothamley, G. H., Hanifa, Y., Islam, K., Claxton, A. P., Packe, G. E., Moore-Gillon, J. C., Darmalingam, M., Davidson, R. N., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(10)61889-2 · Cited by 581 · see citing works

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

Tobin, D. M., Roca, F. J., Oh, S. F., McFarland, R., Vickery, T. W., Ray, J. P., Ko, D. C., Zou, Y., Bang, N. D., Chau, T. T. H., et al. (2012) · Cell · doi:10.1016/j.cell.2011.12.023 · Cited by 576 · see citing works

Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort study

Badri, M., Wilson, D., & Wood, R. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08904-3 · Cited by 552 · see citing works

Metformin as adjunct antituberculosis therapy

Singhal, A., Jie, L., Kumar, P., Hong, G. S., Leow, M. K.-S., Paleja, B., Tsenova, L., Kurepina, N., Chen, J., Zolezzi, F., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009885 · Cited by 547 · see citing works

Thalidomide in the treatment of lepra reactions

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Accelerated Course of Human Immunodeficiency Virus Infection after Tuberculosis

Whalen, C., Horsburgh, C. R., Hom, D., Lahart, C., Simberkoff, M. S., & Ellner, J. J. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.151.1.7812542 · Cited by 532 · see citing works

Glucocorticoid use, other associated factors, and the risk of tuberculosis

Jick, S. S., Lieberman, E. S., Rahman, M. U., & Choi, H. K. (2006) · Arthritis Care & Research · doi:10.1002/art.21705 · Cited by 477 · see citing works

HIV-1 and recurrence, relapse, and reinfection of tuberculosis after cure: a cohort study in South African mineworkers

Sonnenberg, P., Murray, J., Glynn, J. R., Shearer, S., Kambashi, B. S., & Godfrey‐Faussett, P. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06712-5 · Cited by 435 · see citing works

High-Dose Rifapentine with Moxifloxacin for Pulmonary Tuberculosis

Jindani, A., Harrison, T. S., Nunn, A., Phillips, P. P. J., Churchyard, G., Charalambous, S., Hatherill, M., Geldenhuys, H. D., McIlleron, H., Zvada, S., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1314210 · Cited by 430 · see citing works

Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response

Briken, V., Porcelli, S. A., Besra, G. S., & Kremer, L. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04183.x · Cited by 425 · see citing works

The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: Results from ATTRACT, a multicenter, randomized, double‐blind, placebo‐controlled trial

Clair, E. W. S., Wagner, C. L., Fasanmade, A. A., Wang, B., Schaible, T. F., Kavanaugh, A., & Keystone, E. C. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10302 · Cited by 416 · see citing works

A Four-Month Gatifloxacin-Containing Regimen for Treating Tuberculosis

Merle, C. S., Fielding, K., Bah-Sow, O. Y., Gninafon, M., Lo, M. B., Mthiyane, T., Odhiambo, J. A., Amukoye, E., Bah, B., Kassa, F., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1315817 · Cited by 399 · see citing works

Vitamin D as Supplementary Treatment for Tuberculosis

Wejse, C. M., Gomes, V. F., Rabna, P., Gustafson, P., Aaby, P., Lisse, I. M., Andersen, P. L., Glerup, H., & Sodemann, M. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200804-567oc · Cited by 396 · see citing works

Etanercept for the Treatment of Stage II and III Progressive Pulmonary Sarcoidosis

Utz, J. P., LIMPER, A. H., Kalra, S., Specks, U., Scott, J. P., Vuk-Pavlović, Z., & Schroeder, D. R. (2003) · CHEST Journal · doi:10.1378/chest.124.1.177 · Cited by 386 · see citing works

Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection

Renna, M., Schaffner, C., Brown, K., Shang, S., Henao-Tamayo, M. I., Hegyi, K., Grimsey, N. J., Cusens, D., Coulter, S., Cooper, J. F., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci46095 · Cited by 316 · see citing works

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment

Coussens, A. K., Wilkinson, R. J., Hanifa, Y., Nikolayevskyy, V., Elkington, P. T., Islam, K., Timms, P. M., Venton, T. R., Bothamley, G. H., Packe, G. E., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200072109 · Cited by 310 · see citing works

Macrophages in tuberculosis: friend or foe

Guirado, E., Schlesinger, L. S., & Kaplan, G. (2013) · Seminars in Immunopathology · doi:10.1007/s00281-013-0388-2 · Cited by 309 · see citing works

Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation.

Parihar, S. P., Guler, R., Khutlang, R., Lang, D. M., Hurdayal, R., Mhlanga, M., Suzuki, H., Marais, A. D., & Brombacher, F. (2014) · Journal of Infectious Diseases · doi:10.1093/infdis/jit550 · Cited by 295 · see citing works

The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion.

Ew, N., Amin, Z., & Rumende, C. M. (2006) · PubMed · Cited by 267 · see citing works

Macrophages Acquire Neutrophil Granules for Antimicrobial Activity against Intracellular Pathogens

Tan, B. H., Meinken, C., Bastian, M., Bruns, H., Legaspi, A., Ochoa, M. T., Krutzik, S. R., Bloom, B. R., Ganz, T., Modlin, R. L., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.3.1864 · Cited by 267 · see citing works

S100A8/A9 Proteins Mediate Neutrophilic Inflammation and Lung Pathology during Tuberculosis

Gopal, R., Monin, L., Torres‐García, D., Slight-Webb, S. R., Mehra, S., McKenna, K. C., Junecko, B. A. F., Reinhart, T. A., Kolls, J. K., Báez-Saldaña, R., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201304-0803oc · Cited by 259 · see citing works

Adjunctive Corticosteroid Therapy for Tuberculosis: A Critical Reappraisal of the Literature

Dooley, D. P., Carpenter, J. L., & Rademacher, S. (1997) · Clinical Infectious Diseases · doi:10.1086/515543 · Cited by 259 · see citing works

Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth

Stanley, S. A., Barczak, A. K., Silvis, M. R., Luo, S. S., Sogi, K., Vokes, M., Bray, M.-A., Carpenter, A. E., Moore, C. B., Siddiqi, N., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1003946 · Cited by 251 · see citing works

Mycobacterium tuberculosis Activates Human Macrophage Peroxisome Proliferator-Activated Receptor γ Linking Mannose Receptor Recognition to Regulation of Immune Responses

Rajaram, M. V. S., Brooks, M. N., Morris, J. D., Torrelles, J. B., Azad, A. K., & Schlesinger, L. S. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000866 · Cited by 246 · see citing works

A Trial of Mass Isoniazid Preventive Therapy for Tuberculosis Control

Churchyard, G. J., Fielding, K. L., Lewis, J. J., Coetzee, L., Corbett, E. L., Godfrey-Faussett, P., Hayes, R. J., Chaisson, R. E., & Grant, A. D. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1214289 · Cited by 238 · see citing works

A study of the safety, immunology, virology, and microbiology of adjunctive etanercept in HIV-1-associated tuberculosis

Wallis, R. S., Kyambadde, P., Johnson, J. L., Horter, L., Kittle, R., Pohle, M., Ducar, C., Millard, M., Mayanja‐Kizza, H., Whalen, C. C., et al. (2004) · AIDS · doi:10.1097/00002030-200401230-00015 · Cited by 224 · see citing works

Ibuprofen Therapy Resulted in Significantly Decreased Tissue Bacillary Loads and Increased Survival in a New Murine Experimental Model of Active Tuberculosis

Vilaplana, C., Marzo, E., Tapia, G., Diaz, J., Garcia, V., & Cardona, P.-J. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit152 · Cited by 220 · see citing works

Granulomatous Infections Due to Tumor Necrosis Factor Blockade: Correction

Wallis, R. S., Broder, M. S., Wong, J., & Beenhouwer, D. O. (2004) · Clinical Infectious Diseases · doi:10.1086/424455 · Cited by 218 · see citing works

Letting SleepingdosLie: Does Dormancy Play a Role in Tuberculosis?

Chao, M. C., & Rubin, E. J. (2010) · Annual Review of Microbiology · doi:10.1146/annurev.micro.112408.134043 · Cited by 210 · see citing works

Corticosteroids for prevention of mortality in people with tuberculosis: a systematic review and meta-analysis

Critchley, J., Young, F., Orton, L., & Garner, P. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(12)70321-3 · Cited by 209 · see citing works

A double-blind, placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: effects on clinical response and nutritional status

Karyadi, E., West, C. E., Schultink, W., Nelwan, R. H. H., Gross, R., Amin, Z., Dolmans, W. M. V., Schlebusch, H., & van der Meer, J. W. M. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.4.720 · Cited by 209 · see citing works

Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa

Martineau, A. R., Nhamoyebonde, S., Oni, T., Rangaka, M. X., Marais, S., Bangani, N., Tsekela, R., Bashe, L., Azevedo, V. D., Caldwell, J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1111825108 · Cited by 208 · see citing works

Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis

Napier, R. J., Rafi, W., Cheruvu, M., Powell, K. R., Zaunbrecher, M. A., Bornmann, W. G., Salgame, P., Shinnick, T. M., & Kalman, D. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.09.010 · Cited by 205 · see citing works

Increased Release of Interleukin-1 Beta, Interleukin-6, and Tumor Necrosis Factor-Alpha by Bronchoalveolar Cells Lavaged From Involved Sites in Pulmonary Tuberculosis

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Antibody-Mediated Immunity against Tuberculosis: Implications for Vaccine Development

Achkar, J. M., & Casadevall, A. (2013) · Cell Host & Microbe · doi:10.1016/j.chom.2013.02.009 · Cited by 181 · see citing works

Therapeutic Use of Infliximab in Tuberculosis to Control Severe Paradoxical Reaction of the Brain and Lymph Nodes

Blackmore, T., Manning, L. A., Taylor, W. J., & Wallis, R. S. (2008) · Clinical Infectious Diseases · doi:10.1086/592695 · Cited by 178 · see citing works

Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis

Mortaz, E., Adcock, I. M., Tabarsi, P., Masjedi, M. R., Mansouri, D., Velayati, A. A., Casanova, J., & Barnes, P. J. (2014) · Journal of Clinical Immunology · doi:10.1007/s10875-014-0103-7 · Cited by 174 · see citing works

Chronic obstructive airways disease following treated pulmonary tuberculosis

WILLCOX, P. A., & Ferguson, A. D. (1989) · Respiratory Medicine · doi:10.1016/s0954-6111(89)80031-9 · Cited by 165 · see citing works

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis

Chen, R. Y., Dodd, L. E., Lee, M., Paripati, P., Hammoud, D. A., Mountz, J. M., Jeon, D., Zia, N., Zahiri, H., Coleman, M. T., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009501 · Cited by 157 · see citing works

Doxycycline and HIV Infection Suppress Tuberculosis-induced Matrix Metalloproteinases

Walker, N. F., Clark, S. O., Oni, T., Andreu, N., Tezera, L. B., Singh, S., Saraiva, L., Pedersen, B., Kelly, D. L. F., Tree, J. A., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201110-1769oc · Cited by 144 · see citing works

Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial

Skrahin, A., Ahmed, R. K. S., Ferrara, G., Rane, L., Poiret, T., Isaikina, Y., Skrahina, A. M., Zumla, A. I., & Maeurer, M. J. (2014) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(13)70234-0 · Cited by 142 · see citing works

L-arginine and Vitamin D Adjunctive Therapies in Pulmonary Tuberculosis: A Randomised, Double-Blind, Placebo-Controlled Trial

Ralph, A. P., Waramori, G., Pontororing, G. J., Kenangalem, E., Wiguna, A., Tjitra, E., Sandjaja, Lolong, D. B., Yeo, T. W., Chatfield, M. D., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070032 · Cited by 141 · see citing works

Phenylbutyrate Induces Antimicrobial Peptide Expression

Steinmann, J., Halldórsson, S., Agerberth, B., & Gudmundsson, G. H. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00818-09 · Cited by 140 · see citing works

Immunoadjuvant Prednisolone Therapy for HIV‐Associated Tuberculosis: A Phase 2 Clinical Trial in Uganda

Mayanja‐Kizza, H., Jones‐López, E. C., Okwera, A., Wallis, R. S., Ellner, J. J., Mugerwa, R. D., & Whalen, C. C. (2005) · The Journal of Infectious Diseases · doi:10.1086/427995 · Cited by 137 · see citing works

Adjunctive Thalidomide Therapy for Childhood Tuberculous Meningitis: Results of a Randomized Study

Schoeman, J. F., Springer, P. E., van Rensburg, A. J., Swanevelder, S. A., Hanekom, W. A., Haslett, P. A. J., & Kaplan, G. (2004) · Journal of Child Neurology · doi:10.1177/088307380401900402 · Cited by 132 · see citing works

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis

Coleman, M. T., Chen, R. Y., Lee, M., Lin, P. L., Dodd, L. E., Maiello, P. A., Via, L. E., Kim, Y., Marriner, G. A., Dartois, V. A., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009500 · Cited by 131 · see citing works

Aspirin and ibuprofen enhance pyrazinamide treatment of murine tuberculosis

Byrne, S. T., Denkin, S. M., & Zhang, Y. (2006) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkl486 · Cited by 131 · see citing works

Adalimumab Treatment of Life‐Threatening Tuberculosis

Wallis, R. S., van Vuuren, C., & Potgieter, S. (2009) · Clinical Infectious Diseases · doi:10.1086/598504 · Cited by 129 · see citing works

Pulmonary impairment after tuberculosis and its contribution to TB burden

Pasipanodya, J. G., McNabb, S. J. N., Hilsenrath, P. E., Bae, S., Lykens, K., Vecino, E., Munguia, G., Miller, T. L., Drewyer, G., & Weis, S. E. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-259 · Cited by 126 · see citing works

Recurrent TB: relapse or reinfection? The effect of HIV in a general population cohort in Malawi

Crampin, A. C., Mwaungulu, J. N., Mwaungulu, F. D., Mwafulirwa, D. T., Munthali, K., Floyd, S., Fine, P., & Glynn, J. R. (2010) · AIDS · doi:10.1097/qad.0b013e32832f51cf · Cited by 125 · see citing works

Clinical studies on the management of periodontal diseases utilizing subantimicrobial dose doxycycline (SDD)

Caton, J. G., & RYAN, M. E. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2010.12.003 · Cited by 125 · see citing works

A delicate dance: host response to mycobacteria

Huynh, K. K., Joshi, S. A., & Brown, E. J. (2011) · Current Opinion in Immunology · doi:10.1016/j.coi.2011.06.002 · Cited by 123 · see citing works

Immunomodulation with Recombinant Interferon-γ1b in Pulmonary Tuberculosis

Dawson, R., Condos, R., Tse, D. B., Huie, M. L., Ress, S., Tseng, C., Brauns, C., Weiden, M. D., Hoshino, Y., Bateman, E. D., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006984 · Cited by 120 · see citing works

Simvastatin increases the in vivo activity of the first-line tuberculosis regimen

Skerry, C. M., Pinn, M. L., Bruiners, N., Pine, R. I., Gennaro, M. L., & Karakousis, P. C. (2014) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dku166 · Cited by 119 · see citing works

Randomized Trial of Adjunctive Interleukin-2 in Adults with Pulmonary Tuberculosis

Johnson, J. L., Ssekasanvu, E., Okwera, A., Mayanja‐Kizza, H., Hirsch, C. S., Nakibali, J. G., Jankus, D. D., Eisenach, K. D., Boom, W. H., Ellner, J. J., et al. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200211-1359oc · Cited by 115 · see citing works

Abelson Tyrosine Kinase Controls Phagosomal Acidification Required for Killing of <i>Mycobacterium tuberculosis</i> in Human Macrophages

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