The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain

Liquid-Liquid Phase Separation in Biology

Hyman, A. A., Weber, C. A., & Jülicher, F. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013325 · Cited by 3,155

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

Patel, A., Lee, H. O., Jawerth, L. M., Maharana, S., Jahnel, M., Hein, M. Y., Stoynov, S., Mahamid, J., Saha, S., Franzmann, T. M., et al. (2015) · Cell · doi:10.1016/j.cell.2015.07.047 · Cited by 2,927

Widespread transcription at neuronal activity-regulated enhancers

Kim, T.-K., Hemberg, M., Gray, J. M., Costa, A. M., Bear, D. M., Wu, J., Harmin, D. A., Laptewicz, M., Barbara-Haley, K., Kuersten, S., et al. (2010) · Nature · doi:10.1038/nature09033 · Cited by 2,450

The economics of ribosome biosynthesis in yeast

Warner, J. R. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01460-7 · Cited by 1,933

Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

Adelman, K., & Lis, J. T. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3293 · Cited by 1,221

Controlling the elongation phase of transcription with P-TEFb

Peterlin, B. M., & Price, D. H. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.06.014 · Cited by 1,144

Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity

Ng, H., Robert, F., Young, R. A., & Struhl, K. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00092-3 · Cited by 1,131

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcriptionPreprint

Komarnitsky, P. B., Cho, E., & Buratowski, S. (2000) · Genes & Development · doi:10.1101/gad.824700 · Cited by 1,098

Histone exchange, chromatin structure and the regulation of transcription

Venkatesh, S., & Workman, J. L. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3941 · Cited by 997

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

Burke, K. A., Janke, A. M., Rhine, C. L., & Fawzi, N. L. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.09.006 · Cited by 932

Divergent Transcription from Active Promoters

Seila, A. C., Calabrese, J. M., Levine, S. S., Yeo, G. W.-M., Rahl, P. B., Flynn, R. A., Young, R. A., & Sharp, P. A. (2008) · Science · doi:10.1126/science.1162253 · Cited by 930

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

McCracken, S. A., Fong, N., Yankulov, K., Ballantyne, S. M., Pan, G., Greenblatt, J., Patterson, S. D., Wickens, M., & Bentley, D. L. (1997) · Nature · doi:10.1038/385357a0 · Cited by 925

Getting up to speed with transcription elongation by RNA polymerase II

Jonkers, I., & Lis, J. T. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3953 · Cited by 876

Coupling mRNA processing with transcription in time and space

Bentley, D. L. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3662 · Cited by 828

Progression through the RNA Polymerase II CTD Cycle

Buratowski, S. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.10.019 · Cited by 777

The RNA polymerase II CTD coordinates transcription and RNA processingPreprint

Hsin, J.-P., & Manley, J. L. (2012) · Genes & Development · doi:10.1101/gad.200303.112 · Cited by 728

Phase separation in biology; functional organization of a higher order

Mitrea, D. M., & Kriwacki, R. W. (2016) · Cell Communication and Signaling · doi:10.1186/s12964-015-0125-7 · Cited by 727

The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation

Krogan, N. J., Dover, J., Wood, A., Schneider, J., Heidt, J. W., Boateng, M. A., Dean, K., Ryan, O. W., Golshani, A., Johnston, M., et al. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00091-1 · Cited by 726

Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II

Krogan, N. J., Kim, M., Tong, A. H. Y., Golshani, A., Cagney, G., Canadien, V., Richards, D. P., Beattie, B. K., Emili, A., Boone, C. M., et al. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.12.4207-4218.2003 · Cited by 699

Phase separation in biology

Alberti, S. (2017) · Current Biology · doi:10.1016/j.cub.2017.08.069 · Cited by 656

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

Jonkers, I., Kwak, H., & Lis, J. T. (2014) · eLife · doi:10.7554/elife.02407 · Cited by 581

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M., Streicher, W. W., Jungmichel, S., Nielsen, M. L., et al. (2015) · Nature Communications · doi:10.1038/ncomms9088 · Cited by 581

Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing

Nojima, T., Gomes, T., Grosso, A. R. F., Kimura, H., Dye, M. J., Dhir, S., Carmo-Fonseca, M., & Proudfoot, N. J. (2015) · Cell · doi:10.1016/j.cell.2015.03.027 · Cited by 562

The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II

Kim, M., Krogan, N. J., Vasiljeva, L., Rando, O. J., Nedea, E. C., Greenblatt, J., & Buratowski, S. (2004) · Nature · doi:10.1038/nature03041 · Cited by 557

Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains

Kwon, I., Kato, M., Xiang, S., Wu, L. C., Theodoropoulos, P., Mirzaei, H., Han, T. W., Xie, S., Corden, J. L., & McKnight, S. L. (2013) · Cell · doi:10.1016/j.cell.2013.10.033 · Cited by 555

5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase IIPreprint

McCracken, S. A., Fong, N., Rosonina, E., Yankulov, K., Brothers, G. M., Siderovski, D. P., Hessel, A., Foster, S., Program, A. E., Shuman, S., et al. (1997) · Genes & Development · doi:10.1101/gad.11.24.3306 · Cited by 548

The cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

Blazek, D., Kohoutek, J., Bartholomeeusen, K., Johansen, E., Hulinkova, P., Luo, Z., Cimermancic, P., Ule, J., & Peterlin, B. M. (2011) · Genes & Development · doi:10.1101/gad.16962311 · Cited by 522

Phosphorylation of Serine 2 within the RNA Polymerase II C-Terminal Domain Couples Transcription and 3′ End Processing

Ahn, S., Kim, M., & Buratowski, S. (2004) · Molecular Cell · doi:10.1016/s1097-2765(03)00492-1 · Cited by 517

A Novel Domain in Set2 Mediates RNA Polymerase II Interaction and Couples Histone H3 K36 Methylation with Transcript Elongation

Kizer, K. O., Phatnani, H. P., Shibata, Y., Hall, H., Greenleaf, A. L., & Strahl, B. D. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.8.3305-3316.2005 · Cited by 511

Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells

Cissé, I. I., Izeddin, I., Causse, S., Boudarène, L., Senecal, A., Mureşan, L., Dugast‐Darzacq, C., Hajj, B., Dahan, M., & Darzacq, X. (2013) · Science · doi:10.1126/science.1239053 · Cited by 507

RNA transcription modulates phase transition-driven nuclear body assembly

Berry, J., Weber, S. C., Vaidya, N., Haataja, M., & Brangwynne, C. P. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1509317112 · Cited by 501

The RNA Polymerase II Carboxy-Terminal Domain (CTD) Code

Eick, D., & Geyer, M. (2013) · Chemical Reviews · doi:10.1021/cr400071f · Cited by 500

Uniform transitions of the general RNA polymerase II transcription complex

Mayer, A., Lidschreiber, M., Siebert, M., Leike, K., Söding, J., & Cramer, P. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1903 · Cited by 446

Topoisomerases facilitate transcription of long genes linked to autism

King, I. F. G., Yandava, C., Mabb, A. M., Hsiao, J. S., Huang, H., Pearson, B. L., Calabrese, J. M., Starmer, J., Parker, J. S., Magnuson, T., et al. (2013) · Nature · doi:10.1038/nature12504 · Cited by 430

Cracking the RNA polymerase II CTD code

Egloff, S., & Murphy, S. (2008) · Trends in Genetics · doi:10.1016/j.tig.2008.03.008 · Cited by 423

Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeastPreprint

Xiao, T., Hall, H., Kizer, K. O., Shibata, Y., Hall, M. C., Borchers, C. H., & Strahl, B. D. (2003) · Genes & Development · doi:10.1101/gad.1055503 · Cited by 421

Cap and cap‐binding proteins in the control of gene expression

Topisirović, I., Svitkin, Y. V., Sonenberg, N., & Shatkin, A. J. (2010) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.52 · Cited by 413

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1Preprint

Bartkowiak, B., Liu, P., Phatnani, H. P., Fuda, N. J., Cooper, J. J., Price, D. H., Adelman, K., Lis, J. T., & Greenleaf, A. L. (2010) · Genes & Development · doi:10.1101/gad.1968210 · Cited by 404

Dynamic association of capping enzymes with transcribing RNA polymerase IIPreprint

Schroeder, S. C., Schwer, B., Shuman, S., & Bentley, D. L. (2000) · Genes & Development · doi:10.1101/gad.836300 · Cited by 387

BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain

Devaiah, B. N., Lewis, B. A., Cherman, N., Hewitt, M. C., Albrecht, B. K., Robey, P. G., Ozato, K., Sims, R. J., & Singer, D. S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120422109 · Cited by 386

The Set2 Histone Methyltransferase Functions through the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II

Li, B., Howe, L. J., Anderson, S., Yates, J. R., & Workman, J. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212134200 · Cited by 374

Native Elongating Transcript Sequencing Reveals Human Transcriptional Activity at Nucleotide Resolution

Mayer, A., di Iulio, J., Maleri, S., Eser, U., Vierstra, J., Reynolds, A., Sandstrom, R., Stamatoyannopoulos, J. A., & Churchman, L. S. (2015) · Cell · doi:10.1016/j.cell.2015.03.010 · Cited by 367

Transcriptional Regulation inSaccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and Coactivators

Hahn, S., & Young, E. T. (2011) · Genetics · doi:10.1534/genetics.111.127019 · Cited by 361

The CTD code

Buratowski, S. (2003) · Nature Structural & Molecular Biology · doi:10.1038/nsb0903-679 · Cited by 350

Transcription termination and the control of the transcriptome: why, where and how to stop

Porrúa, O., & Libri, D. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3943 · Cited by 349

Distinct Roles for CTD Ser-2 and Ser-5 Phosphorylation in the Recruitment and Allosteric Activation of Mammalian mRNA Capping Enzyme

Ho, C. K., & Shuman, S. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80468-2 · Cited by 343

The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.Preprint

Myers, L., Gustafsson, C., Bushnell, D., Lui, M., Erdjument-Bromage, H., Tempst, P., & Kornberg, R. (1998) · Genes & Development · doi:10.1101/gad.12.1.45 · Cited by 329

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

Lu, H., Flores, O. A., Weinmann, R. S., & Reinberg, D. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.22.10004 · Cited by 325

Transcribing RNA Polymerase II Is Phosphorylated at CTD Residue Serine-7

Chapman, R. D., Heidemann, M., Albert, T., Mailhammer, R., Flatley, A., Meisterernst, M., Kremmer, E., & Eick, D. (2007) · Science · doi:10.1126/science.1145977 · Cited by 323

Functional Interaction of Yeast Pre-mRNA 3′ End Processing Factors with RNA Polymerase II

Licatalosi, D. D., Geiger, G., Minet, M., Schroeder, S. C., Cilli, K., McNeil, J. B., & Bentley, D. L. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00518-x · Cited by 316

Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factors

Meinhart, A., & Cramer, P. (2004) · Nature · doi:10.1038/nature02679 · Cited by 315

NELF and DSIF cause promoter proximal pausing on thehsp70promoter inDrosophilaPreprint

Wu, C.-H., Yamaguchi, Y., Benjamin, L. R., Horvat‐Gordon, M., Washinsky, J., Enerly, E., Larsson, J., Lambertsson, A., Handa, H., & Gilmour, D. S. (2003) · Genes & Development · doi:10.1101/gad.1091403 · Cited by 314

RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription

Baranello, L., Wójtowicz, D., Cui, K., Devaiah, B. N., Chung, H., Chan-Salis, K. Y., Guha, R., Wilson, K. M., Zhang, X., Zhang, H., et al. (2016) · Cell · doi:10.1016/j.cell.2016.02.036 · Cited by 304

Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription

Heidemann, M., Hintermair, C., Voß, K., & Eick, D. (2012) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2012.08.013 · Cited by 300

Droplet organelles?

Courchaine, E. M., Lü, A., & Neugebauer, K. M. (2016) · The EMBO Journal · doi:10.15252/embj.201593517 · Cited by 295

Regulation of RNA polymerase II activation by histone acetylation in single living cells

Stasevich, T. J., Hayashi‐Takanaka, Y., Sato, Y., Maehara, K., Ohkawa, Y., Sakata-Sogawa, K., Tokunaga, M., Nagase, T., Nozaki, N., McNally, J. G., et al. (2014) · Nature · doi:10.1038/nature13714 · Cited by 294

Serine-7 of the RNA Polymerase II CTD Is Specifically Required for snRNA Gene Expression

Egloff, S., O’Reilly, D., Chapman, R. D., Taylor, A., Tanzhaus, K., Pitts, L., Eick, D., & Murphy, S. (2007) · Science · doi:10.1126/science.1145989 · Cited by 294

Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II.

Cadena, D. L., & Dahmus, M. E. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45229-5 · Cited by 293

The LC Domain of hnRNPA2 Adopts Similar Conformations in Hydrogel Polymers, Liquid-like Droplets, and Nuclei

Xiang, S., Kato, M., Wu, L. C., Lin, Y., Ding, M., Zhang, Y., Yu, Y., & McKnight, S. L. (2015) · Cell · doi:10.1016/j.cell.2015.10.040 · Cited by 291

RNA Polymerase II cluster dynamics predict mRNA output in living cells

Cho, W., Jayanth, N., English, B. P., Inoue, T., Andrews, J. O., Conway, W., Grimm, J. B., Spille, J.-H., Lavis, L. D., Lionnet, T., et al. (2016) · eLife · doi:10.7554/elife.13617 · Cited by 291

The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain

Vasiljeva, L., Kim, M., Mutschler, H., Buratowski, S., & Meinhart, A. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1468 · Cited by 290

Association of the Histone Methyltransferase Set2 with RNA Polymerase II Plays a Role in Transcription Elongation

Li, J., Moazed, D., & Gygi, S. P. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209294200 · Cited by 274

TFIIH Phosphorylation of the Pol II CTD Stimulates Mediator Dissociation from the Preinitiation Complex and Promoter Escape

Wong, K. H., Jin, Y., & Struhl, K. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.03.024 · Cited by 265

Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II.

Nonet, M. L., & Young, R. A. (1989) · Genetics · doi:10.1093/genetics/123.4.715 · Cited by 259

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylationPreprint

Yoh, S. M., Lucas, J., & Jones, K. A. (2008) · Genes & Development · doi:10.1101/gad.1720008 · Cited by 258

CTD Tyrosine Phosphorylation Impairs Termination Factor Recruitment to RNA Polymerase II

Mayer, A., Heidemann, M., Lidschreiber, M., Schreieck, A., Sun, M., Hintermair, C., Kremmer, E., Eick, D., & Cramer, P. (2012) · Science · doi:10.1126/science.1219651 · Cited by 257

Termination of Cryptic Unstable Transcripts Is Directed by Yeast RNA-Binding Proteins Nrd1 and Nab3

Arigo, J. T., Eyler, D. E., Carroll, K. L., & Corden, J. L. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.07.024 · Cited by 257

The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and exportPreprint

Yoh, S. M., Cho, H. K., Pickle, L., Evans, R. M., & Jones, K. A. (2007) · Genes & Development · doi:10.1101/gad.1503107 · Cited by 257

PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II

Chen, F., Woodfin, A. R., Gardini, A., Rickels, R. A., Marshall, S. A., Smith, E. R., Shiekhattar, R., & Shilatifard, A. (2015) · Cell · doi:10.1016/j.cell.2015.07.042 · Cited by 253

3D imaging of Sox2 enhancer clusters in embryonic stem cells

Liu, Z. J., Legant, W. R., Chen, B., Li, L., Grimm, J. B., Lavis, L. D., Betzig, E., & Tjian, R. (2014) · eLife · doi:10.7554/elife.04236 · Cited by 252

SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination

Zhao, D. Y., Gish, G. D., Braunschweig, U., Li, Y., Ni, Z., Schmitges, F. W., Zhong, G., Liu, K., Li, W., Moffat, J., et al. (2015) · Nature · doi:10.1038/nature16469 · Cited by 250

Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.

West, M. L., & Corden, J. L. (1995) · Genetics · doi:10.1093/genetics/140.4.1223 · Cited by 245

Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons

Oesterreich, F. C., Preibisch, S., & Neugebauer, K. M. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.11.004 · Cited by 244

RNA polymerase II–associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II

Yu, M., Yang, W., Ni, T., Tang, Z., Nakadai, T., Zhu, J., & Roeder, R. G. (2015) · Science · doi:10.1126/science.aad2338 · Cited by 241

Transcription Termination and Nuclear Degradation of Cryptic Unstable Transcripts: A Role for the Nrd1-Nab3 Pathway in Genome Surveillance

Thiebaut, M., Kisseleva-Romanova, E., Rougemaille, M., Boulay, J., & Libri, D. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.07.029 · Cited by 241

The transition of RNA polymerase II from initiation to elongation is associated with phosphorylation of the carboxyl-terminal domain of subunit IIa

Payne, J., Laybourn, P. J., & Dahmus, M. E. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)47159-7 · Cited by 240

FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2Preprint

Schwartz, J. C., Ebmeier, C. C., Podell, E. R., Heimiller, J., Taatjes, D. J., & Cech, T. R. (2012) · Genes & Development · doi:10.1101/gad.204602.112 · Cited by 240

Gcn5 Promotes Acetylation, Eviction, and Methylation of Nucleosomes in Transcribed Coding Regions

Govind, C. K., Zhang, F., Qiu, H., Hofmeyer, K., & Hinnebusch, A. G. (2007) · Molecular Cell · doi:10.1016/j.molcel.2006.11.020 · Cited by 238

Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex

Robinson, P. J. J., Trnka, M. J., Bushnell, D. A., Davis, R., Matteï, P., Burlingame, A. L., & Kornberg, R. D. (2016) · Cell · doi:10.1016/j.cell.2016.08.050 · Cited by 238

Gene-specific RNA polymerase II phosphorylation and the CTD code

Kim, H., Erickson, B., Luo, W., Seward, D. J., Graber, J. H., Pollock, D. D., Megee, P. C., & Bentley, D. L. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1913 · Cited by 235

The pol II CTD: new twists in the tail

Zaborowska, J., Egloff, S., & Murphy, S. (2016) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3285 · Cited by 235

The C-Terminal Domain of RNA Polymerase II Is Modified by Site-Specific Methylation

Sims, R. J., Rojas, L. A., Beck, D. B., Bonasio, R., Schüller, R., Drury, W. J., Eick, D., & Reinberg, D. (2011) · Science · doi:10.1126/science.1202663 · Cited by 228

Participation of the nuclear cap binding complex in pre-mRNA 3′ processing

Flaherty, S. M., Fortes, P., Izaurralde, E., Mattaj, I. W., & Gilmartin, G. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.22.11893 · Cited by 227

Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II

Oesterreich, F. C., Herzel, L., Straube, K., Hujer, K., Howard, J., & Neugebauer, K. M. (2016) · Cell · doi:10.1016/j.cell.2016.02.045 · Cited by 226

Wdr82 Is a C-Terminal Domain-Binding Protein That Recruits the Setd1A Histone H3-Lys4 Methyltransferase Complex to Transcription Start Sites of Transcribed Human Genes

Lee, J., & Skalnik, D. G. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01356-07 · Cited by 223

The maintenance of chromosome structure: positioning and functioning of SMC complexes

Jeppsson, K. E., Kanno, T., Shirahige, K., & Sjögren, C. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3857 · Cited by 220

A Universal RNA Polymerase II CTD Cycle Is Orchestrated by Complex Interplays between Kinase, Phosphatase, and Isomerase Enzymes along Genes

Bataille, A. R., Jerónimo, C., Jacques, P., Laramée, L., Fortin, M.-È., Forest, A., Bergeron, M., Hanes, S. D., & Robert, F. (2012) · Molecular Cell · doi:10.1016/j.molcel.2011.11.024 · Cited by 220

Phosphorylated Pol II CTD Recruits Multiple HDACs, Including Rpd3C(S), for Methylation-Dependent Deacetylation of ORF Nucleosomes

Govind, C. K., Qiu, H., Ginsburg, D. S., Ruan, C., Hofmeyer, K., Hu, C., Venkatesh, S., Workman, J. L., Li, B., & Hinnebusch, A. G. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.07.003 · Cited by 216

Transcription-associated histone modifications and cryptic transcription

Smolle, M., & Workman, J. L. (2012) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2012.08.008 · Cited by 215

Low-complexity regions within protein sequences have position-dependent roles

Coletta, A., Pinney, J. W., Solís, D. W., Marsh, J., Pettifer, S. R., & Attwood, T. K. (2010) · BMC Systems Biology · doi:10.1186/1752-0509-4-43 · Cited by 209

The Splicing Factor, Prp40, Binds the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II

Morris, D. P., & Greenleaf, A. L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004118200 · Cited by 198

Characterization of Human Cyclin-Dependent Kinase 12 (CDK12) and CDK13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and RNA Processing

Liang, K., Gao, X., Gilmore, J. M., Florens, L. A., Washburn, M. P., Smith, E. R., & Shilatifard, A. (2015) · Molecular and Cellular Biology · doi:10.1128/mcb.01426-14 · Cited by 194

RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template

Corden, J. L. (2013) · Chemical Reviews · doi:10.1021/cr400158h · Cited by 192

The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65–Prp19 complexPreprint

David, C. J., Boyne, A. R., Millhouse, S., & Manley, J. L. (2011) · Genes & Development · doi:10.1101/gad.2038011 · Cited by 191

Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition

Czudnochowski, N., Bösken, C. A., & Geyer, M. (2012) · Nature Communications · doi:10.1038/ncomms1846 · Cited by 191

The structure and substrate specificity of human Cdk12/Cyclin K

Bösken, C. A., Farnung, L., Hintermair, C., Merzel Schachter, M., Vogel-Bachmayr, K., Blazek, D., Anand, K., Fisher, R. P., Eick, D., & Geyer, M. (2014) · Nature Communications · doi:10.1038/ncomms4505 · Cited by 191

RNAP II CTD Phosphorylated on Threonine-4 Is Required for Histone mRNA 3′ End Processing

Hsin, J.-P., Sheth, A., & Manley, J. L. (2011) · Science · doi:10.1126/science.1206034 · Cited by 178

The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation

Schaft, D. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg372 · Cited by 176

Molecular evolution of the RNA polymerase II CTD

Chapman, R. D., Heidemann, M., Hintermair, C., & Eick, D. (2008) · Trends in Genetics · doi:10.1016/j.tig.2008.03.010 · Cited by 165

Evidence of the Involvement of O-GlcNAc-modified Human RNA Polymerase II CTD in Transcription in Vitro and in Vivo

Ranuncolo, S. M., Ghosh, S. K., Hanover, J. A., Hart, G. W., & Lewis, B. A. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.330910 · Cited by 164

Threonine‐4 of mammalian RNA polymerase II CTD is targeted by Polo‐like kinase 3 and required for transcriptional elongation

Hintermair, C., Heidemann, M., Koch, F., Descostes, N., Gut, M., Gut, I. G., Fenouil, R., Ferrier, P., Flatley, A., Kremmer, E., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.123 · Cited by 161

Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain

Lunde, B. M., Reichow, S., Kim, M., Suh, H., Leeper, T. C., Yang, F., Mutschler, H., Buratowski, S., Meinhart, A., & Varani, G. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1893 · Cited by 159

P-TEFb Is Critical for the Maturation of RNA Polymerase II into Productive Elongation In Vivo

Ni, Z., Saunders, A., Fuda, N. J., Yao, J., Suárez, J.-R., Webb, W. W., & Lis, J. T. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01859-07 · Cited by 157

Kin28 regulates the transient association of Mediator with core promoters

Jerónimo, C., & Robert, F. (2014) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2810 · Cited by 156

Hyperphosphorylation of the C-terminal Repeat Domain of RNA Polymerase II Facilitates Dissociation of Its Complex with Mediator*

Max, T., Søgaard, M., & Svejstrup, J. Q. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m701345200 · Cited by 150

Heptad-Specific Phosphorylation of RNA Polymerase II CTD

Schüller, R., Forné, I., Straub, T., Schreieck, A., Texier, Y., Shah, N., Decker, T.-M., Cramer, P., Imhof, A., & Eick, D. (2016) · Molecular Cell · doi:10.1016/j.molcel.2015.12.003 · Cited by 150

Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue

Harlen, K. M., Trotta, K. L., Smith, E. E., Mosaheb, M. M., Fuchs, S. M., & Churchman, L. S. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.010 · Cited by 150

Phosphorylation of the Yeast Rpb1 C-terminal Domain at Serines 2, 5, and 7

Kim, M., Suh, H., Cho, E., & Buratowski, S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.028993 · Cited by 149

Chemical-genomic dissection of the CTD code

Tietjen, J. R., Zhang, D. W., Rodríguez‐Molina, J. B., White, B. E., Akhtar, M. S., Heidemann, M., Li, X., Chapman, R. D., Shokat, K. M., Keleş, S., et al. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1900 · Cited by 148

DSIF and RNA Polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes

Drouin, S., Laramée, L., Jacques, P., Forest, A., Bergeron, M., & Robert, F. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001173 · Cited by 143

Deciphering the RNA Polymerase II CTD Code in Fission Yeast

Schwer, B., & Shuman, S. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.05.024 · Cited by 135

The RNA Polymerase II CTD: The Increasing Complexity of a Low-Complexity Protein Domain

Jerónimo, C., Collin, P., & Robert, F. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.02.006 · Cited by 135

Recruitment Timing and Dynamics of Transcription Factors at the Hsp70 Loci in Living Cells

Zobeck, K. L., Buckley, M. S., Zipfel, W. R., & Lis, J. T. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.11.022 · Cited by 131

Interaction of yeast RNA-binding proteins Nrd1 and Nab3 with RNA polymerase II terminator elements

Carroll, K. L., Ghirlando, R., Ames, J. M., & Corden, J. L. (2007) · RNA · doi:10.1261/rna.338407 · Cited by 130

Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II

Robinson, P. J. J., Bushnell, D. A., Trnka, M. J., Burlingame, A. L., & Kornberg, R. D. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215241109 · Cited by 121

Direct Analysis of Phosphorylation Sites on the Rpb1 C-Terminal Domain of RNA Polymerase II

Suh, H., Ficarro, S. B., Kang, U., Chun, Y., Marto, J. A., & Buratowski, S. (2016) · Molecular Cell · doi:10.1016/j.molcel.2015.12.021 · Cited by 121

The Writers, Readers, and Functions of the RNA Polymerase II C-Terminal Domain Code

Jerónimo, C., Bataille, A. R., & Robert, F. (2013) · Chemical Reviews · doi:10.1021/cr4001397 · Cited by 120

A Genome-Wide Analysis Indicates that Yeast Pre-mRNA Splicing Is Predominantly Posttranscriptional

Tardiff, D. F., Lacadie, S. A., & Rosbash, M. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.12.002 · Cited by 117

Acetylation of RNA Polymerase II Regulates Growth-Factor-Induced Gene Transcription in Mammalian Cells

Schröder, S., Herker, E., Itzen, F., He, D. X., Thomas, S., Gilchrist, D. A., Kaehlcke, K., Cho, S., Pollard, K. S., Capra, J. A., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.10.009 · Cited by 115

CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo

Gu, B., Eick, D., & Bensaude, O. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1327 · Cited by 114

NuA4 Lysine Acetyltransferase Esa1 Is Targeted to Coding Regions and Stimulates Transcription Elongation with Gcn5

Ginsburg, D. S., Govind, C. K., & Hinnebusch, A. G. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01033-09 · Cited by 113

Intranuclear Distribution and Local Dynamics of RNA Polymerase II during Transcription Activation

Yao, J., Ardehali, M. B., Fecko, C. J., Webb, W. W., & Lis, J. T. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.10.017 · Cited by 111

Structure and Carboxyl-terminal Domain (CTD) Binding of the Set2 SRI Domain That Couples Histone H3 Lys36 Methylation to Transcription

Vojnic, E., Simon, B., Strahl, B. D., Sattler, M., & Cramer, P. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.c500423200 · Cited by 99

Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells

Descostes, N., Heidemann, M., Spinelli, L., Schüller, R., Maqbool, M. A., Fenouil, R., Koch, F., Innocenti, C., Gut, M., Gut, I. G., et al. (2014) · eLife · doi:10.7554/elife.02105 · Cited by 99

Wwp2-Mediated Ubiquitination of the RNA Polymerase II Large Subunit in Mouse Embryonic Pluripotent Stem Cells

Li, H., Zhang, Z., Wang, B., Zhang, J., Zhao, Y., & Jin, Y. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01667-06 · Cited by 87

A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)

Sun, M., Larivière, L., Dengl, S., Mayer, A., & Cramer, P. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.144568 · Cited by 87

Dissecting the role of low-complexity regions in the evolution of vertebrate proteins

Radó-Trilla, N., & Albà, M. M. (2012) · BMC Evolutionary Biology · doi:10.1186/1471-2148-12-155 · Cited by 86

Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR‐independent recruitment of Paf1 complex

Qiu, H., Hu, C., Gaur, N. A., & Hinnebusch, A. G. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.188 · Cited by 82

Functional Unit of the RNA Polymerase II C-Terminal Domain Lies within Heptapeptide Pairs

Stiller, J. W., & Cook, M. S. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.3.735-740.2004 · Cited by 79

The CTD code of RNA polymerase II: a structural view

Jasnovidova, O., & Štefl, R. (2012) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1138 · Cited by 78

The Cap and the 3′ Splice Site Similarly Affect Polyadenylation Efficiency

Cooke, C., & Alwine, J. C. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.6.2579 · Cited by 76

H3K4 Trimethylation by Set1 Promotes Efficient Termination by the Nrd1-Nab3-Sen1 Pathway

Çizmecioğlu, N. T., Churchman, L. S., Vasiljeva, L., Weissman, J. S., & Buratowski, S. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05590-11 · Cited by 76

Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization

Rodríguez‐Molina, J. B., Tseng, S. C., Simonett, S. P., Taunton, J., & Ansari, A. Z. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.06.036 · Cited by 74

Differential Recruitment of the Splicing Machinery during Transcription Predicts Genome-Wide Patterns of mRNA Splicing

Moore, M. J., Schwartzfarb, E. M., Silver, P. A., & Yu, M. C. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.12.006 · Cited by 70

RecQL5 Promotes Genome Stabilization through Two Parallel Mechanisms—Interacting with RNA Polymerase II and Acting as a Helicase

Islam, M. N., Fox, D., Guo, R., Enomoto, T., & Wang, W. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.01583-09 · Cited by 70

RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

Kanagaraj, R., Hühn, D., MacKellar, A. L., Menigatti, M., Zheng, L., Urban, V., Shevelev, I., Greenleaf, A. L., & Janščák, P. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq697 · Cited by 70

Protein modifications in transcription elongation

Fuchs, S. M., Laribee, R. N., & Strahl, B. D. (2008) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2008.07.008 · Cited by 67

DNA topology and transcription

Kouzine, F., Levens, D., & Baranello, L. (2014) · Nucleus · doi:10.4161/nucl.28909 · Cited by 65

Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast

Schwer, B., Bitton, D. A., Sánchez, A. M., Bähler, J., & Shuman, S. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321842111 · Cited by 62

Strand‐specific, high‐resolution mapping of modified RNA polymerase II

Milligan, L., Huynh‐Thu, V. A., Delan‐Forino, C., Tuck, A., Petfalski, E., Lombraña, R., Sanguinetti, G., Kudla, G., & Tollervey, D. W. (2016) · Molecular Systems Biology · doi:10.15252/msb.20166869 · Cited by 57

Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo.

Schwer, B., & Shuman, S. (1996) · PubMed Central · Cited by 55

RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells

Hsin, J.-P., Li, W., Hoque, M., Tian, B., & Manley, J. L. (2014) · eLife · doi:10.7554/elife.02112 · Cited by 53

Cadmium–cysteine coordination in the BK inner pore region and its structural and functional implications

Zhou, Y., Xia, X., & Lingle, C. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1500953112 · Cited by 50

Punctuation and syntax of the RNA polymerase II CTD code in fission yeast

Schwer, B., Sánchez, A. M., & Shuman, S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208995109 · Cited by 49

The Set2-RPB1 Interaction Domain of Human RECQ5 Is Important for Transcription-Associated Genome Stability

Li, M., Xu, X., & Liu, Y. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.01137-10 · Cited by 48

Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas

Bartkowiak, B., Yan, C. M., & Greenleaf, A. L. (2015) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2015.07.010 · Cited by 46

Trypanosoma brucei RNA polymerase II is phosphorylated in the absence of carboxyl-terminal domain heptapeptide repeats.

Chapman, A., & Agabian, N. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37608-1 · Cited by 43

Mapping RNA exit channel on transcribing RNA polymerase II by FRET analysis

Chen, C., Chang, C., Yen, C., Chiu, M. T.-K., & Chang, W. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811689106 · Cited by 42

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells

Dias, J. D., Rito, T., Triglia, E. T., Kukalev, A., Ferrai, C., Chotalia, M., Brookes, E., Kimurâ, H., & Pombo, A. (2015) · eLife · doi:10.7554/elife.11215 · Cited by 39

Distributive O-GlcNAcylation on the Highly Repetitive C-Terminal Domain of RNA Polymerase II

Lü, L., Fan, D., Hu, C., Worth, M., Ma, Z., & Jiang, J. (2016) · Biochemistry · doi:10.1021/acs.biochem.5b01280 · Cited by 34

Topoisomerases, chromatin and transcription termination

Durand‐Dubief, M., Svensson, J. P., Persson, J., & Ekwall, K. (2011) · Transcription · doi:10.4161/trns.2.2.14411 · Cited by 34

Threonine-4 of the budding yeast RNAP II CTD couples transcription with Htz1-mediated chromatin remodeling

Rosonina, E., Yurko, N., Li, W., Hoque, M., Tian, B., & Manley, J. L. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1412802111 · Cited by 33

Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II

Voß, K., Forné, I., Descostes, N., Hintermair, C., Schüller, R., Maqbool, M. A., Heidemann, M., Flatley, A., Imhof, A., Gut, M., et al. (2015) · Transcription · doi:10.1080/21541264.2015.1114983 · Cited by 28

The C-Terminal Domain of Rpb1 Functions on Other RNA Polymerase II Subunits

Suh, H., Hazelbaker, D. Z., Soares, L. M., & Buratowski, S. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.08.015 · Cited by 23

Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat

Liu, J., Fan, S., Lee, C., Greenleaf, A. L., & Zhou, P. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.460238 · Cited by 23

Specific threonine-4 phosphorylation and function of RNA polymerase II CTD during M phase progression

Hintermair, C., Voß, K., Forné, I., Heidemann, M., Flatley, A., Kremmer, E., Imhof, A., & Eick, D. (2016) · Scientific Reports · doi:10.1038/srep27401 · Cited by 23

Distinct requirement of RNA polymerase II CTD phosphorylations in budding and fission yeast

Cassart, C., Drogat, J., Migeot, V., & Hermand, D. (2012) · Transcription · doi:10.4161/trns.21066 · Cited by 23

Getting Access to Low-Complexity Domain Modifications

Schüller, R., & Eick, D. (2016) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2016.05.010 · Cited by 12

DNA Instability Maintains the Repeat Length of the Yeast RNA Polymerase II C-terminal Domain

Morrill, S., Exner, A. E., Babokhov, M., Reinfeld, B. I., & Fuchs, S. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.696252 · Cited by 9

Organizational principles of 3D genome architecture

Rowley, M. J., & Corces, V. G. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0060-8 · Cited by 1,171

The molecular language of membraneless organelles

Gomes, E., & Shorter, J. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.tm118.001192 · Cited by 804

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

Guo, Y. E., Manteiga, J. C., Henninger, J. E., Sabari, B. R., Dall’Agnese, A., Hannett, N. M., Spille, J.-H., Afeyan, L. K., Zamudio, A. V., Shrinivas, K., et al. (2019) · Nature · doi:10.1038/s41586-019-1464-0 · Cited by 674

Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II

Lu, H., Yu, D., Hansen, A. S., Ganguly, S., Liu, R., Heckert, A. B., Darzacq, X., & Zhou, Q. (2018) · Nature · doi:10.1038/s41586-018-0174-3 · Cited by 576

Born to run: control of transcription elongation by RNA polymerase II

Chen, F. X., Smith, E. R., & Shilatifard, A. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0010-5 · Cited by 447

Cracking the RNA polymerase II CTD code

Egloff, S., & Murphy, S. (2008) · Trends in Genetics · doi:10.1016/j.tig.2008.03.008 · Cited by 423

doi:10.1155/2012/347214 Review Article Emerging Views on the CTD Code

Zhang, D., Rodrı́guez-molina, J. B., Tietjen, J. R., Nemec, C., & Ansari, A. Z. (2011)

RNA polymerase II carboxy-terminal domain with multiple connections

Cho, E. (2007) · Experimental & Molecular Medicine · doi:10.1038/emm.2007.28 · Cited by 28

Emerging Views on the CTD Code

Zhang, D. W., Rodríguez‐Molina, J. B., Tietjen, J. R., Nemec, C. M., & Ansari, A. Z. (2012) · Genetics Research International · doi:10.1155/2012/347214 · Cited by 58

Investigating the Structural Basis of the CTD Code

Gibbs, E. B., & Showalter, S. A. (2015) · The FASEB Journal · doi:10.1096/fasebj.29.1_supplement.712.13