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Epigenetic Regulation in Neurodegenerative Diseases

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The epigenetic basis of cellular heterogeneity

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The DNA methylation landscape in cancer

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Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression

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Transgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring health

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Causes and consequences of RNA polymerase II stalling during transcript elongation

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FACT caught in the act of manipulating the nucleosome

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Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

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Chromatin accessibility profiling methods

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Structural basis of the nucleosome transition during RNA polymerase II passage

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In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras -Mutant Lung Adenocarcinoma

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Epigenetic regulation of abiotic stress memory: maintaining the good things while they last

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NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release

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ChromBPNet: bias factorized, base-resolution deep learning models of chromatin accessibility reveal cis-regulatory sequence syntax, transcription factor footprints and regulatory variantsPreprint

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Phase separation directs ubiquitination of gene-body nucleosomes

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Energy-driven genome regulation by ATP-dependent chromatin remodellers

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Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation

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Epigenetic regulation of thermomorphogenesis and heat stress tolerance

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RSC-Associated Subnucleosomes Define MNase-Sensitive Promoters in Yeast

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Sequence-Directed Action of RSC Remodeler and General Regulatory Factors Modulates +1 Nucleosome Position to Facilitate Transcription

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Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity

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Structural basis of nucleosome transcription mediated by Chd1 and FACT

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Opposing chromatin remodelers control transcription initiation frequency and start site selection

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Epigenetics in hepatocellular carcinoma development and therapy: The tip of the iceberg

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Super-enhancers: critical roles and therapeutic targets in hematologic malignancies

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Beads on a string—nucleosome array arrangements and folding of the chromatin fiber

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Identification of a DNA N6-Adenine Methyltransferase Complex and Its Impact on Chromatin Organization

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Histone Recycling by FACT and Spt6 during Transcription Prevents the Scrambling of Histone Modifications

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Single-cell multi-omics in cancer immunotherapy: from tumor heterogeneity to personalized precision treatment

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The Paf1 Complex: A Keystone of Nuclear Regulation Operating at the Interface of Transcription and Chromatin

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Structure of transcribing RNA polymerase II-nucleosome complex

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Dietary Modulation of the Epigenome

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Multiscale modeling of genome organization with maximum entropy optimization

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Single-cell sequencing technology applied to epigenetics for the study of tumor heterogeneity

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Transcription through the nucleosome

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The Histone H3 Lysine 4 Presenter WDR5 as an Oncogenic Protein and Novel Epigenetic Target in Cancer

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NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region

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Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders

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The nucleosome core particle remembers its position through DNA replication and RNA transcription

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Ruler elements in chromatin remodelers set nucleosome array spacing and phasing

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Multiscale footprints reveal the organization of cis-regulatory elements

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Mechanosensing dysregulation in the fibroblast: A hallmark of the aging heart

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DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network

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Fragmentomic analysis of circulating tumor DNA-targeted cancer panels

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Structures of +1 nucleosome–bound PIC-Mediator complex

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Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

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Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes

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FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner

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Replication-dependent histone isoforms: a new source of complexity in chromatin structure and function

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Single-molecule long-read sequencing reveals the chromatin basis of gene expressionPreprint

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KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance

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Targeting Chromatin Remodeling for Cancer Therapy

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Sentinels of chromatin: chromodomain helicase DNA-binding proteins in development and diseasePreprint

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Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin

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Shared genetic and epigenetic changes link aging and cancer

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Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression

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DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network

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Transcription-coupled repair of DNA–protein cross-links depends on CSA and CSB

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Structure of transcribing RNA polymerase II-nucleosome complex

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Genome information processing by the INO80 chromatin remodeler positions nucleosomes

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Regulation of neuronal connectivity in the mammalian brain by chromatin remodeling

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General Regulatory Factors Control the Fidelity of Transcription by Restricting Non-coding and Ectopic Initiation

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CTCF-dependent chromatin boundaries formed by asymmetric nucleosome arrays with decreased linker length

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DNA mechanics and its biological impact

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Structure of a backtracked hexasomal intermediate of nucleosome transcription

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Structural transition of the nucleosome during chromatin remodeling and transcription

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Pharmacological targeting of the cancer epigenome

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Histone chaperone FACT FAcilitates Chromatin Transcription: mechanistic and structural insights

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Resetting the Yeast Epigenome with Human Nucleosomes

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Chromatin remodelers couple inchworm motion with twist-defect formation to slide nucleosomal DNA

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Structural visualization of key steps in nucleosome reorganization by human FACT

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Unravelling the role of epigenetics in reproductive adaptations to early-life environment

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Investigating the Dynamics of Destabilized Nucleosomes Using Methyl-TROSY NMR

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Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications

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Current and Emerging Methods for the Synthesis of Single-Stranded DNA

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PARP1 exhibits enhanced association and catalytic efficiency with γH2A.X-nucleosome

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The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain

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Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication

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