Adipocyte differentiation from the inside out

Prevalence of Overweight and Obesity in the United States, 1999-2004

Ogden, C. L., Carroll, M. D., Curtin, L. R., McDowell, M. A., Tabak, C. J., & Flegal, K. M. (2006) · JAMA · doi:10.1001/jama.295.13.1549 · Cited by 8,720

The Wnt Signaling Pathway in Development and Disease

Logan, C. Y., & Nusse, R. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.113126 · Cited by 5,325

Prevalence of Overweight and Obesity in the United States

Crespo, C. J., & Smit, E. (2003) · Human Kinetics eBooks · doi:10.5040/9781718206601.ch-001 · Cited by 4,382

Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

McBeath, R., Pirone, D. M., Nelson, C. M., Bhadriraju, K., & Chen, C. S. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00075-9 · Cited by 4,182

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Tontonoz, P., Hu, E., & Spiegelman, B. M. (1994) · Cell · doi:10.1016/0092-8674(94)90006-x · Cited by 3,564

Smad transcription factorsPreprint

Massagué, J., Seoane, J., & Wotton, D. (2005) · Genes & Development · doi:10.1101/gad.1350705 · Cited by 2,519

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

Picard, F., Kurtev, M. V., Chung, N., Topark‐Ngarm, A., Senawong, T., de Oliveira, R. M., Leid, M. E., McBurney, M. W., & Guarente, L. (2004) · Nature · doi:10.1038/nature02583 · Cited by 1,943

Transcriptional regulation of adipogenesisPreprint

Rosen, E. D., Walkey, C. J., Puigserver, P., & Spiegelman, B. M. (2000) · Genes & Development · doi:10.1101/gad.14.11.1293 · Cited by 1,908

Inhibition of Adipogenesis by Wnt Signaling

Ross, S. E., Hemati, N., Longo, K. A., Bennett, C. N., Lucas, P. C., Erickson, R. L., & MacDougald, O. A. (2000) · Science · doi:10.1126/science.289.5481.950 · Cited by 1,876

C/EBPα induces adipogenesis through PPARγ: a unified pathwayPreprint

Rosen, E. D., Hsu, C.-H., Wang, X., Sakai, S., Freeman, M. W., Gonzalez, F. J., & Spiegelman, B. M. (2002) · Genes & Development · doi:10.1101/gad.948702 · Cited by 1,497

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism.Preprint

Kim, J. B., & Spiegelman, B. M. (1996) · Genes & Development · doi:10.1101/gad.10.9.1096 · Cited by 1,026

Cross-Regulation of C/EBPα and PPARγ Controls the Transcriptional Pathway of Adipogenesis and Insulin Sensitivity

Wu, Z., Rosen, E. D., Brun, R. P., Hauser, S., Adelmant, G., Troy, A. E., McKeon, C., Darlington, G., & Spiegelman, B. M. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80306-8 · Cited by 1,015

TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation

Hong, J.-H., Hwang, E. S., McManus, M. T., Amsterdam, A., Tian, Y., Kalmukova, R., Mueller, E., Benjamin, T., Spiegelman, B. M., Sharp, P. A., et al. (2005) · Science · doi:10.1126/science.1110955 · Cited by 1,009

Adipokines: molecular links between obesity and atheroslcerosis

Lau, D., Dhillon, B., Yan, H., Szmitko, P. E., & Verma, S. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01058.2004 · Cited by 953

Regulation of osteoblastogenesis and bone mass by Wnt10b

Bennett, C. N., Longo, K. A., Hahn, W. S., Suva, L. J., Lane, T. F., Hankenson, K. D., & MacDougald, O. A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408742102 · Cited by 898

PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

Akune, T., Ohba, S., Kamekura, S., Yamaguchi, M., Chung, U., Kubota, N., Terauchi, Y., Harada, Y., Azuma, Y., Nakamura, K., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19900 · Cited by 869

Wnt signaling in osteoblasts and bone diseases

Westendorf, J. J., Kahler, R. A., & Schroeder, T. M. (2004) · Gene · doi:10.1016/j.gene.2004.06.044 · Cited by 820

The Role of C/EBP Genes in Adipocyte Differentiation*

Darlington, G., Ross, S. E., & Macdougald, O. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.46.30057 · Cited by 807

Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

Blüher, M., Michael, M. D., Peroni, O. D., Ueki, K., Carter, N., Kahn, B. B., & Kahn, C. R. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00199-5 · Cited by 806

Communicating with Hedgehogs

Hooper, J. E., & Scott, M. P. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1622 · Cited by 806

Defective adipocyte differentiation in mice lacking the C/EBPβ and/or C/EBPδ gene

Tanaka, T., Yoshida, N., Kishimoto, T., & Akira, S. (1997) · The EMBO Journal · doi:10.1093/emboj/16.24.7432 · Cited by 804

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

Kim, J. B., Sarraf, P., Wright, M., Yao, K., Mueller, E., Solanes, G., Lowell, B. B., & Spiegelman, B. M. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1411 · Cited by 792

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

Shimomura, I., Hammer, R. E., Richardson, J. A., Ikemoto, S., Bashmakov, Y., Goldstein, J. L., & Brown, M. S. (1998) · Genes & Development · doi:10.1101/gad.12.20.3182 · Cited by 790

Regulation of Wnt Signaling during Adipogenesis

Bennett, C. N., Ross, S. E., Longo, K. A., Bajnok, L., Hemati, N., Johnson, K. W., Harrison, S. D., & MacDougald, O. A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204527200 · Cited by 743

PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

Akune, T., Ohba, S., Kamekura, S., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200419900 · Cited by 730

The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation

Nakae, J., Kitamura, T., Kitamura, Y., Biggs, W., Arden, K. C., & Accili, D. (2003) · Developmental Cell · doi:10.1016/s1534-5807(02)00401-x · Cited by 729

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ

Garofalo, R. S., Orena, S. J., Rafidi, K., Torchia, A. J., Stock, J. L., Hildebrandt, A. L., Coskran, T., Black, S. C., Brees, D. J., Wicks, J. R., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16885 · Cited by 726

ADD1/SREBP1 activates PPARγ through the production of endogenous ligand

Kim, J. B., Wright, H. M., Wright, M., & Spiegelman, B. M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.8.4333 · Cited by 670

Evidence for a role of developmental genes in the origin of obesity and body fat distribution.

Gesta, S., Blüher, M., Yamamoto, Y., Norris, A., Berndt, J., Kralisch, S., Boucher, J., Lewis, C., & Kahn, C. (2006) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0601752103 · Cited by 635

Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium.

Hauner, H., Entenmann, G., Wabitsch, M., Gaillard, D., Ailhaud, G. P., Négrel, R., & Pfeiffer, E. F. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114345 · Cited by 621

Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes

Himms-Hagen, J., Melnyk, A., Zingaretti, M. C., Ceresi, E., Barbatelli, G., & Cinti, S. (2000) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.2000.279.3.c670 · Cited by 593

The role of MAPKs in adipocyte differentiation and obesity

Bost, F., Aouadi, M., Caron, L., & Binétruy, B. (2004) · Biochimie · doi:10.1016/j.biochi.2004.10.018 · Cited by 583

Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis

Rebbapragada, A., Benchabane, H., Wrana, J. L., Celeste, A. J., & Attisano, L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.20.7230-7242.2003 · Cited by 573

A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2

George, S., Rochford, J. J., Wolfrum, C., Gray, S. L., Schinner, S., Wilson, J. C., Soos, M. A., Murgatroyd, P. R., Williams, R. M., Acerini, C. L., et al. (2004) · Science · doi:10.1126/science.1096706 · Cited by 562

Adipose Development: From Stem Cell to Adipocyte

Otto, T. C., & Lane, M. D. (2005) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230591008189 · Cited by 553

Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis

Shimba, S., Ishii, N., Ohta, Y., Ohno, T., Watabe, Y., Hayashi, M., Wada, T., Aoyagi, T., & Tezuka, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502383102 · Cited by 536

Function of GATA Transcription Factors in Preadipocyte-Adipocyte Transition

Tong, Q., Dalgin, G., Xu, H., Ting, C.-N., Leiden, J. M., & Hotamışlıgil, G. S. (2000) · Science · doi:10.1126/science.290.5489.134 · Cited by 534

Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

Clément-Lacroix, P., Ai, M., Morvan, F., Roman‐Roman, S., Vayssière, B., Belleville, C., Estrera, K. A., Warman, M. L., Baron, R., & Rawadi, G. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505259102 · Cited by 524

Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.

Smith, P. J., Wise, L. S., Berkowitz, R., Wan, C. F., & Rubin, C. S. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76555-7 · Cited by 511

Suppression of body fat accumulation in myostatin-deficient mice

McPherron, A. C., & Lee, S.-J. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0213562 · Cited by 505

Bone Morphogenetic Protein-2 Causes Commitment and Differentiation in C3Hl0T1/2 and 3T3 Cells

Wang, E. A., Israel, D. I., Kelly, S. J., & Luxenberg, D. P. (1993) · Growth Factors · doi:10.3109/08977199308991582 · Cited by 490

CCAAT/enhancer-binding protein β is required for mitotic clonal expansion during adipogenesis

Tang, Q.-Q., Otto, T. C., & Lane, M. D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337434100 · Cited by 479

Regulation of Peroxisome Proliferator–Activated Receptor-γ Activity by Mammalian Target of Rapamycin and Amino Acids in Adipogenesis

Kim, J. E., & Chen, J. (2004) · Diabetes · doi:10.2337/diabetes.53.11.2748 · Cited by 478

Mice Lacking Paternally Expressed Pref-1/Dlk1 Display Growth Retardation and Accelerated Adiposity

Moon, Y. S., Smas, C. M., Lee, K., Villena, J. A., Kim, K., Yun, E. J., & Sul, H. S. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.15.5585-5592.2002 · Cited by 473

Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation

Oishi, Y., Manabe, I., Tobe, K., Tsushima, K., Shindo, T., Fujiu, K., Nishimura, G., Maemura, K., Yamauchi, T., Kubota, N., et al. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2004.11.005 · Cited by 461

SRC-1 and TIF2 Control Energy Balance between White and Brown Adipose Tissues

Picard, F., Géhin, M., Annicotte, J., Rocchi, S., Champy, M., O’Malley, B. W., Chambon, P., & Auwerx, J. H. (2002) · Cell · doi:10.1016/s0092-8674(02)01169-8 · Cited by 444

Rosiglitazone Causes Bone Loss in Mice by Suppressing Osteoblast Differentiation and Bone Formation

Ali, A., Weinstein, R. S., Stewart, S. A., PARFITT, A. M., Manolagas, S. C., & Jilka, R. L. (2005) · Endocrinology · doi:10.1210/en.2004-0735 · Cited by 444

Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

Tang, Q.-Q., Otto, T. C., & Lane, M. D. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403100101 · Cited by 415

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

Shimano, H., Shimomura, I., Hammer, R. E., Herz, J., Goldstein, J. L., Brown, M. S., & Horton, J. D. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119746 · Cited by 395

Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis

Sordella, R., Jiang, W., Chen, G., Curto, M., & Settleman, J. E. (2003) · Cell · doi:10.1016/s0092-8674(03)00271-x · Cited by 384

Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse

Imai, T., Takakuwa, R., Marchand, S., Dentz, E., Bornert, J., Messaddeq, N., Wendling, O., Mark, M. P., Desvergne, B., Wahli, W., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400356101 · Cited by 383

Biological control through regulated transcriptional coactivators

Spiegelman, B. M., & Heinrich, R. (2004) · Cell · doi:10.1016/j.cell.2004.09.037 · Cited by 377

Wnt10b Inhibits Development of White and Brown Adipose Tissues

Longo, K. A., Hahn, W. S., Kang, S., Gerin, I., Chiang, S.-H., Lucas, P. C., Opp, M. R., & MacDougald, O. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402937200 · Cited by 372

Testosterone Inhibits Adipogenic Differentiation in 3T3-L1 Cells: Nuclear Translocation of Androgen Receptor Complex with β-Catenin and T-Cell Factor 4 May Bypass Canonical Wnt Signaling to Down-Regulate Adipogenic Transcription Factors

Singh, R., Artaza, J. N., Taylor, W. E., Braga, M., Yuan, X., Gonzalez-Cadavid, N. F., & Bhasin, S. (2006) · Endocrinology · doi:10.1210/en.2004-1649 · Cited by 369

PPARγ knockdown by engineered transcription factors: exogenous PPARγ2 but not PPARγ1 reactivates adipogenesisPreprint

Ren, D., Collingwood, T. N., Rebar, E. J., Wolffe, A. P., & Camp, H. S. (2002) · Genes & Development · doi:10.1101/gad.953802 · Cited by 362

Adipogenesis: forces that tip the scales

MacDougald, O. A., & Mandrup, S. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(01)00517-3 · Cited by 355

C/EBPα is required for differentiation of white, but not brown, adipose tissue

Linhart, H., Ishimura‐Oka, K., DeMayo, F. J., Kibe, T., Repka, D., Poindexter, B. J., Bick, R. J., & Darlington, G. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211416898 · Cited by 349

Transforming Growth Factor-β Inhibits Adipocyte Differentiation by Smad3 Interacting with CCAAT/Enhancer-binding Protein (C/EBP) and Repressing C/EBP Transactivation Function

Choy, L., & Derynck, R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212259200 · Cited by 343

Role of Krüppel-like Factor 15 (KLF15) in Transcriptional Regulation of Adipogenesis

Mori, T., Sakaue, H., Iguchi, H., Gomi, H., Okada, Y., Takashima, Y., Nakamura, K., Nakamura, T., Yamauchi, T., Kubota, N., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m410515200 · Cited by 340

Msx2 Promotes Osteogenesis and Suppresses Adipogenic Differentiation of Multipotent Mesenchymal Progenitors

Cheng, S., Shao, J.-S., Charlton-Kachigian, N., Loewy, A. P., & Towler, D. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306972200 · Cited by 332

Roles of Autocrine TGF-β Receptor and Smad Signaling in Adipocyte Differentiation

Choy, L., Skillington, J., & Derynck, R. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.3.667 · Cited by 322

Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis

Ge, K., Guermah, M., Yuan, C., Ito, M., Wallberg, A. E., Spiegelman, B. M., & Roeder, R. G. (2002) · Nature · doi:10.1038/417563a · Cited by 319

Peroxisome-proliferator-activated receptor γ suppresses Wnt/β-catenin signalling during adipogenesis

Moldes, M., Zuo, Y., Morrison, R. F., Silva, D., Park, B.-H., Liu, J., & Farmer, S. R. (2003) · Biochemical Journal · doi:10.1042/bj20030426 · Cited by 312

The Krüppel-like Factor KLF2 Inhibits Peroxisome Proliferator-activated Receptor-γ Expression and Adipogenesis

Banerjee, S. S., Feinberg, M. W., Watanabe, M., Gray, S., Haspel, R. L., Denkinger, D. J., Kawahara, R. S., Hauner, H., & Jain, M. K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210859200 · Cited by 301

Role of Peroxisome Proliferator-Activated Receptor-γ in Maintenance of the Characteristics of Mature 3T3-L1 Adipocytes

Tamori, Y., Masugi, J., Nishino, N., & Kasuga, M. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2045 · Cited by 294

Role of CREB in Transcriptional Regulation of CCAAT/Enhancer-binding Protein β Gene during Adipogenesis

Zhang, J., Klemm, D. J., Vinson, C., & Lane, M. D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m311327200 · Cited by 287

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation

Hansen, J. B., Jørgensen, C., Petersen, R. K., Hallenborg, P., De Matteis, R., Bøye, H. A., Petrovic, N., Enerbäck, S., Nedergaard, J., Cinti, S., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0301964101 · Cited by 287

Selective disruption of PPARγ2 impairs the development of adipose tissue and insulin sensitivity

Zhang, J., Fu, M., Cui, T., Chen, X., Xu, K., Zhong, W., Xiao, Y., Floyd, D., Liang, J., Li, E., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403652101 · Cited by 283

Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice.

Clouthier, D. E., Comerford, S. A., & Hammer, R. E. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119815 · Cited by 282

Hedgehog signaling plays a conserved role in inhibiting fat formation

Suh, J. M., Gao, X., McKay, J., McKay, R. M., Salo, Z., & Graff, J. M. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2005.11.012 · Cited by 279

Cellularity of adipose depots in six strains of genetically obese mice

Johnson, P. R., & Hirsch, J. (1972) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39428-1 · Cited by 278

Cyclin D1 Inhibits Peroxisome Proliferator-activated Receptor γ-mediated Adipogenesis through Histone Deacetylase Recruitment

Fu, M., Rao, M., Bouras, T., Wang, C., Wu, K., Zhang, X., Li, Z., Yao, T., & Pestell, R. G. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500403200 · Cited by 274

De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor

Kawaguchi, N., Toriyama, K., Nicodemou‐Lena, E., Inou, K., Torii, S., & Kitagawa, Y. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1062 · Cited by 270

Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation

Spinella-Jaegle, S., Rawadi, G., Kawai, S., Gallea, S., Faucheu, C., Mollat, P., Courtois, B., Bergaud, B., Ramez, V., Blanchet, A., et al. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.11.2085 · Cited by 267

Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor–1 (Pref-1)

Lee, K., Villena, J. A., Moon, Y. S., Kim, K., Lee, S., Kang, C., & Sul, H. S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci15924 · Cited by 264

A Role for C/EBPβ in Regulating Peroxisome Proliferator-activated Receptor γ Activity during Adipogenesis in 3T3-L1 Preadipocytes

Hamm, J. K., Park, B. H., & Farmer, S. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100797200 · Cited by 260

Microarray Analyses during Adipogenesis: Understanding the Effects of Wnt Signaling on Adipogenesis and the Roles of Liver X Receptor α in Adipocyte Metabolism

Ross, S. E., Erickson, R. L., Gerin, I., DeRose, P. M., Bajnok, L., Longo, K. A., Misek, D. E., Kuick, R. D., Hanash, S., Atkins, K. B., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.16.5989-5999.2002 · Cited by 255

The Kru¨ppel-like Factor KLF15 Regulates the Insulin-sensitive Glucose Transporter GLUT4

Gray, S., Feinberg, M. W., Hull, S., Kuo, C. T., Watanabe, M., Banerjee, S. S., DePina, A., Haspel, R. L., & Jain, M. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201304200 · Cited by 254

Activated Liver X Receptors Stimulate Adipocyte Differentiation through Induction of Peroxisome Proliferator-Activated Receptor γ Expression

Seo, J. B., Moon, H. M., Kim, W. S., Lee, Y. S., Jeong, H. W., Yoo, E. J., Ham, J., Kang, H., Park, M.-G., Steffensen, K. R., et al. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.8.3430-3444.2004 · Cited by 250

Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor γ Isoforms

Mueller, E., Drori, S., Aiyer, A., Yie, J., Sarraf, P., Chen, H., Hauser, S., Rosen, E. D., Ge, K., Roeder, R. G., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206950200 · Cited by 248

Interaction between GATA and the C/EBP Family of Transcription Factors Is Critical in GATA-Mediated Suppression of Adipocyte Differentiation

Tong, Q., Tsai, J., Tan, G., Dalgin, G., & Hotamışlıgil, G. S. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.2.706-715.2005 · Cited by 248

The Nuclear Receptor Corepressors NCoR and SMRT Decrease Peroxisome Proliferator-activated Receptor γ Transcriptional Activity and Repress 3T3-L1 Adipogenesis

Yu, C., Markan, K. R., Temple, K. A., Deplewski, D., Brady, M., & Cohen, R. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m409468200 · Cited by 238

A Nuclear Receptor Atlas: 3T3-L1 Adipogenesis

Fu, M., Sun, T., Bookout, A. L., Downes, M., Yu, R. T., Evans, R. M., & Mangelsdorf, D. J. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0539 · Cited by 233

Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies

Giorgino, F., Laviola, L., & Eriksson, J. W. (2005) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.2004.01385.x · Cited by 230

Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes

Skillington, J., Choy, L., & Derynck, R. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200204060 · Cited by 227

Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin

Tseng, Y.-H., Butte, A. J., Kokkotou, E., Yechoor, V. K., Taniguchi, C. M., Kriauciunas, K. M., Cypess, A. M., Niinobe, M., Yoshikawa, K., Patti, M. E., et al. (2005) · Nature Cell Biology · doi:10.1038/ncb1259 · Cited by 222

Activation of Peroxisome Proliferator-activated Receptor-γ Inhibits the Runx2-mediated Transcription of Osteocalcin in Osteoblasts

Jeon, M. J., Kim, J. A., Kwon, S. H., Kim, S. W., Park, K. S., Park, S. W., Kim, S. Y., & Shin, C. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211610200 · Cited by 221

Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: Effect of cofactors on differentiating lineages

Nieden, N. I. Z., Kempka, G., Rancourt, D. E., & Ahr, H.-J. (2005) · BMC Developmental Biology · doi:10.1186/1471-213x-5-1 · Cited by 216

Reconstitution of Insulin-sensitive Glucose Transport in Fibroblasts Requires Expression of Both PPARγ and C/EBPα

Jack, A. K. E., Hamm, J. K., Pilch, P. F., & Farmer, S. R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.12.7946 · Cited by 215

Alternatively Spliced Lipin Isoforms Exhibit Distinct Expression Pattern, Subcellular Localization, and Role in Adipogenesis

Péterfy, M., Phan, J., & Reue, K. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503885200 · Cited by 215

Insulin-induced Adipocyte Differentiation

Klemm, D. J., Leitner, J. W., Watson, P., Nesterova, A., Reusch, J. E. B., Goalstone, M. L., & Draznin, B. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103382200 · Cited by 212

Krox20 stimulates adipogenesis via C/EBPβ-dependent and -independent mechanisms

Chen, Z., Torréns, J. I., Anand, A., Spiegelman, B. M., & Friedman, J. M. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2004.12.009 · Cited by 209

Myostatin Inhibits Myogenesis and Promotes Adipogenesis in C3H 10T(1/2) Mesenchymal Multipotent Cells

Artaza, J. N., Bhasin, S., Magee, T. R., Reisz‐Porszasz, S., Shen, R., Groome, N. P., Fareez, M. M., & González-Cadavid, N. F. (2005) · Endocrinology · doi:10.1210/en.2005-0362 · Cited by 206

Activation of CCAAT/Enhancer-binding Protein (C/EBP) α Expression by C/EBPβ during Adipogenesis Requires a Peroxisome Proliferator-activated Receptor-γ-associated Repression of HDAC1 at the C/ebpα Gene Promoter

Zuo, Y., Qiang, L., & Farmer, S. R. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m510682200 · Cited by 205

Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1α

Scimè, A., Grenier, G., Huh, M. S., Gillespie, M. A., Bevilacqua, L., Harper, M.-E., & Rudnicki, M. A. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.10.002 · Cited by 199

Cooperation between C/EBPα TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiationPreprint

Pedersen, T. Å., Kowenz‐Leutz, E., Leutz, A., & Nerlov, C. (2001) · Genes & Development · doi:10.1101/gad.209901 · Cited by 194

Inhibition of p38MAPK Increases Adipogenesis From Embryonic to Adult Stages

Aouadi, M., Laurent, K., Prot, M., MARCHAND‐BRUSTEL, Y. L., Binétruy, B., & Bost, F. (2006) · Diabetes · doi:10.2337/diabetes.55.02.06.db05-0963 · Cited by 194

Temporal Recruitment of Transcription Factors and SWI/SNF Chromatin-Remodeling Enzymes during Adipogenic Induction of the Peroxisome Proliferator-Activated Receptor γ Nuclear Hormone Receptor

Salma, N., Xiao, H., Mueller, E., & Imbalzano, A. N. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.11.4651-4663.2004 · Cited by 193

TNF -Mediated Inhibition and Reversal of Adipocyte Differentiation Is Accompanied by Suppressed Expression of PPAR without Effects on Pref-1 Expression

Xing, H. Y., Northrop, J. P., Grove, J. R., Kilpatrick, K. E., Su, J., & RINGOLD, G. M. (1997) · Endocrinology · doi:10.1210/endo.138.7.5242 · Cited by 189

Conditional deletion of β-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium

Arango, N. A., Szotek, P. P., Manganaro, T. F., Oliva, E., Donahoe, P. K., & Teixeira, J. M. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.09.045 · Cited by 185

Down-regulation of Histone Deacetylases Stimulates Adipocyte Differentiation

Yoo, E. J., Chung, J.-J., Choe, S. S., Kim, K. H., & Kim, J. B. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m508982200 · Cited by 184

Regulated Production of a Peroxisome Proliferator-activated Receptor-γ Ligand during an Early Phase of Adipocyte Differentiation in 3T3-L1 Adipocytes

Tzameli, I., Fang, H., Ollero, M., Shi, H., Hamm, J. K., Kievit, P., Hollenberg, A. N., & Flier, J. S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405346200 · Cited by 181

Regulatory circuits controlling white versus brown adipocyte differentiation

Hansen, J. B., & Kristiansen, K. (2006) · Biochemical Journal · doi:10.1042/bj20060402 · Cited by 178

Krüppel-like Factor-6 Promotes Preadipocyte Differentiation through Histone Deacetylase 3-dependent Repression of DLK1

Li, D., Yea, S., Li, S., Zhu, C. X., Narla, G., Banck, M. S., Laborda, J., Tan, S., Friedman, J. M., Friedman, S. L., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500463200 · Cited by 177

The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform

Medina‐Gómez, G., Virtue, S., Lelliott, C. J., Boiani, R., Campbell, M., Christodoulides, C., Perrin, C., Jimenez‐Liñan, M., Blount, M., Dixon, J., et al. (2005) · Diabetes · doi:10.2337/diabetes.54.6.1706 · Cited by 176

Differential Roles of Insulin Receptor Substrates in Brown Adipocyte Differentiation

Tseng, Y.-H., Kriauciunas, K. M., Kokkotou, E., & Kahn, C. R. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.5.1918-1929.2004 · Cited by 173

Reciprocal Roles of Msx2 in Regulation of Osteoblast and Adipocyte Differentiation

Ichida, F., Nishimura, R., Hata, K., Matsubara, T., Ikeda, F., Hisada, K., Yatani, H., Cao, X., Komori, T., Yamaguchi, A., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403621200 · Cited by 173

Schnurri-2 Controls BMP-Dependent Adipogenesis via Interaction with Smad Proteins

Jin, W., Takagi, T., Kanesashi, S.-N., Kurahashi, T., Nomura, T., Harada, J., & Ishii, S. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.02.016 · Cited by 170

Cdk4 promotes adipogenesis through PPARγ activation

Abella, A., Dubus, P. R., Malumbres, M., Rane, S. G., Kiyokawa, H., Sicard, A., Vignon, F., Langin, D., Barbacid, M., & Lluis Fajas, A. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.09.003 · Cited by 170

Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells

Jackson, A. M., Vayssière, B., Garcia, T., Newell, W., Baron, R., Roman‐Roman, S., & Rawadi, G. (2005) · Bone · doi:10.1016/j.bone.2005.01.007 · Cited by 169

LXRβ Is Required for Adipocyte Growth, Glucose Homeostasis, and β Cell Function

Gerin, I., Dolinsky, V. W., Shackman, J. G., Kennedy, R. T., Chiang, S.-H., Burant, C., Steffensen, K. R., Gustafsson, J.-Α., & MacDougald, O. A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m412564200 · Cited by 167

Activation of an adipogenic program in adult myoblasts with age

Taylor-Jones, J. M., McGehee, R. E., Rando, T. A., Lecka‐Czernik, B., Lipschitz, D. A., & Peterson, C. A. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(01)00411-0 · Cited by 165

Wnt10b Deficiency Promotes Coexpression of Myogenic and Adipogenic Programs in Myoblasts

Vertino, A. M., Taylor-Jones, J. M., Longo, K. A., Bearden, E. D., Lane, T. F., McGehee, R. E., MacDougald, O. A., & Peterson, C. A. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-08-0720 · Cited by 158

Fibroblast Growth Factor 1

Hutley, L. J., Shurety, W., Newell, F., McGeary, R. P., Pelton, N., Grant, J., Herington, A. C., Cameron, D. P., Whitehead, J. P., & Prins, J. B. (2004) · Diabetes · doi:10.2337/diabetes.53.12.3097 · Cited by 157

Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice

Yamauchi, T., Oike, Y., Kamon, J., Waki, H., Komeda, K., Tsuchida, A., Date, Y., Li, M.-X., Miki, H., Akanuma, Y., et al. (2002) · Nature Genetics · doi:10.1038/ng829 · Cited by 155

Overexpression and Ribozyme-mediated Targeting of Transcriptional Coactivators CREB-binding Protein and p300 Revealed Their Indispensable Roles in Adipocyte Differentiation through the Regulation of Peroxisome Proliferator-activated Receptor γ

Takahashi, N., Kawada, T., Yamamoto, T., Goto, T., Taimatsu, A., Aoki, N., Kawasaki, H., Taira, K., Yokoyama, K. K., Kamei, Y., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200585200 · Cited by 153

Notch-1 Controls the Expression of Fatty Acid-activated Transcription Factors and Is Required for Adipogenesis

Garcés, C., Ruiz‐Hidalgo, M. J., de Mora, J. F., Park, C., Miele, L., Goldstein, J., Bonvini, E., Porrás, A., & Laborda, J. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.47.29729 · Cited by 152

The dynamics of the cycle

Bussell, K. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1612 · Cited by 151

Wnt5b partially inhibits canonical Wnt/β-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes

Kanazawa, A., Tsukada, S., Kamiyama, M., Yanagimoto, T., Nakajima, M., & Maeda, S. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.03.007 · Cited by 148

Dual Roles for the Notch Target Gene Hes-1 in the Differentiation of 3T3-L1 Preadipocytes

Ross, D. A., Rao, P. K., & Kadesch, T. R. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.8.3505-3513.2004 · Cited by 147

Genetic Basis of Lipodystrophies and Management of Metabolic Complications

Agarwal, A. K., & Garg, A. (2006) · Annual Review of Medicine · doi:10.1146/annurev.med.57.022605.114424 · Cited by 145

Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex

Wiper‐Bergeron, N., Wu, D., Pope, L., Schild‐Poulter, C., & Haché, R. J. G. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg218 · Cited by 142

Role of Foxa-2 in adipocyte metabolism and differentiation

Wolfrum, C., Shih, D. Q., Kuwajima, S., Norris, A. W., Kahn, C. R., & Stoffel, M. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18698 · Cited by 139

Lipoatrophic diabetes in Irs1−/−/Irs3−/− double knockout micePreprint

Laustsen, P. G., Michael, M. D., Crute, B. E., Cohen, S. E., Ueki, K., Kulkarni, R. N., Keller, S. R., Lienhard, G. E., & Kahn, C. R. (2002) · Genes & Development · doi:10.1101/gad.1034802 · Cited by 137

Requirement of fibroblast growth factor 10 in development of white adipose tissue.Preprint

Sakaue, H., Konishi, M., Ogawa, W., Asaki, T., Mori, T., Yamasaki, M., Takata, M., Ueno, H., Kato, S., Kasuga, M., et al. (2002) · Genes & Development · doi:10.1101/gad.983202 · Cited by 135

STAT5A Promotes Adipogenesis in Nonprecursor Cells and Associates With the Glucocorticoid Receptor During Adipocyte Differentiation

Floyd, Z. E., & Stephens, J. M. (2003) · Diabetes · doi:10.2337/diabetes.52.2.308 · Cited by 133

Cyclin D3 Promotes Adipogenesis through Activation of Peroxisome Proliferator-Activated Receptor γ

Sarruf, D. A., Iankova, I., Abella, A., Assou, S., Miard, S., & Lluis Fajas, A. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.22.9985-9995.2005 · Cited by 130

Inhibition of Preadipocyte Differentiation by Myostatin Treatment in 3T3-L1 Cultures

Kim, H., Liang, L., Dean, R. G., Hausman, D. B., Hartzell, D. L., & Baile, C. A. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4435 · Cited by 127

Liver X receptors are regulators of adipocyte gene expression but not differentiation

Hummasti, S., Laffitte, B. A., Watson, M. A., Galardi, C. M., Chao, L. C., Ramamurthy, L., Moore, J. T., & Tontonoz, P. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300312-jlr200 · Cited by 120

The KLF2 Transcription Factor Does Not Affect the Formation of Preadipocytes but Inhibits Their Differentiation into Adipocytes

Wu, J., Srinivasan, S. V., Neumann, J. C., & Lingrel, J. B. (2005) · Biochemistry · doi:10.1021/bi050166i · Cited by 117

Early B-Cell Factor (O/E-1) Is a Promoter of Adipogenesis and Involved in Control of Genes Important for Terminal Adipocyte Differentiation

Åkerblad, P., Lind, U., Liberg, D., Bamberg, K., & Sigvardsson, M. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.22.8015-8025.2002 · Cited by 112

Inhibition of Histone Deacetylase Activity by Valproic Acid Blocks Adipogenesis

Lagace, D. C., & Nachtigal, M. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312795200 · Cited by 108

Phosphorylation of GATA2 by Akt Increases Adipose Tissue Differentiation and Reduces Adipose Tissue–Related Inflammation

Menghini, R., Marchetti, V., Cardellini, M., Hribal, M. L., Mauriello, A., Lauro, D., Sbraccia, P., Lauro, R., & Federici, M. (2005) · Circulation · doi:10.1161/01.cir.0000161814.02942.b2 · Cited by 103

Hic-5 regulates an epithelial program mediated by PPARγPreprint

Drori, S., Girnun, G. D., Tou, L., Szwaya, J. D., Mueller, E., Kia, X., Shivdasani, R. A., & Spiegelman, B. M. (2005) · Genes & Development · doi:10.1101/gad.1240705 · Cited by 102

C/EBPβ, When Expressed from the C/ebpα Gene Locus, Can Functionally Replace C/EBPα in Liver but Not in Adipose Tissue

Chen, S., Chen, J., Johnson, P. F., Muppala, V., & Lee, Y. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.19.7292-7299.2000 · Cited by 101

Stimulation of 3T3-L1 Adipogenesis by Signal Transducer and Activator of Transcription 5

Nanbu-Wakao, R., Morikawa, Y., Matsumura, I., Masuho, Y., Muramatsu, M., Senba, E., & Wakao, H. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.7.0862 · Cited by 96

Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes

Kanazawa, A., Kawamura, Y., Sekine, A., Iida, A., Tsunoda, T., Kashiwagi, A., Tanaka, Y., Babazono, T., Matsuda, M., Kawai, K., et al. (2005) · Diabetologia · doi:10.1007/s00125-005-1797-0 · Cited by 95

Myostatin inhibits differentiation of bovine preadipocyte

Hirai, S., Matsumoto, H., Hino, N., Kawachi, H., Matsui, T., & Yano, H. (2005) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2005.12.001 · Cited by 89

ETO/MTG8 Is an Inhibitor of C/EBPβ Activity and a Regulator of Early Adipogenesis

Rochford, J. J., Semple, R. K., Laudes, M., Boyle, K. B., Christodoulides, C., Mulligan, C., Lelliott, C. J., Schinner, S., Hadaschik, D., Mahadevan, M., et al. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.22.9863-9872.2004 · Cited by 87

Modulation of Muscle Regeneration, Myogenesis, and Adipogenesis by the Rho Family Guanine Nucleotide Exchange Factor GEFT

Bryan, B. A., Mitchell, D., Zhao, L., Ma, W., Stafford, L. J., Teng, B., & Liu, M. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.24.11089-11101.2005 · Cited by 86

BMP-2 and Sonic Hedgehog Have Contrary Effects on Adipocyte-Like Differentiation of C3H10T1/2 Cells

Zehentner, B. K., Leser, U., & BURTSCHER, H. J. (2000) · DNA and Cell Biology · doi:10.1089/10445490050021186 · Cited by 84

Distinct effects of PPARγ insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells

Kawaguchi, H., Akune, T., Yamaguchi, M., Ohba, S., Ogata, N., Chung, U., Kubota, N., Terauchi, Y., Kadowaki, T., & Nakamura, K. (2005) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-005-0599-2 · Cited by 79

Role of MAPK Phosphatase-1 (MKP-1) in Adipocyte Differentiation

Sakaue, H., Ogawa, W., Nakamura, T., Mori, T., Nakamura, K., & Kasuga, M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407353200 · Cited by 78

EPAS1 Promotes Adipose Differentiation in 3T3-L1 Cells

Shimba, S., Wada, T., Hara, S., & Tezuka, M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400840200 · Cited by 77

TIPs Are Tension-Responsive Proteins Involved in Myogenic versus Adipogenic Differentiation

Jakkaraju, S., Zhe, X., Pan, D., Choudhury, R., & Schuger, L. A. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.04.015 · Cited by 73

Transcriptional Coactivator PRIP, the Peroxisome Proliferator-activated Receptor γ (PPARγ)-interacting Protein, Is Required for PPARγ-mediated Adipogenesis

Qi, C., Surapureddi, S., Zhu, Y.-J., Yu, S., Kashireddy, P. V., Rao, M. S., & Reddy, J. K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c300175200 · Cited by 65

Molecular Mechanisms of Adipocyte Differentiation and Inhibitory Action of Pref-1

Smas, C. M., & Sul, H. S. (1997) · Critical Reviews in Eukaryotic Gene Expression · doi:10.1615/critreveukargeneexpr.v7.i4.10 · Cited by 61

Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype

Moulin, K., Truel, N., André, M., ARNAULD, E., Nibbelink, M. M., Cousin, B., Dani, C., Pénicaud, L., & Casteilla, L. (2001) · Biochemical Journal · doi:10.1042/bj3560659 · Cited by 59

Autocrine secretion of TGF-β1 and TGF-β2 by pre-adipocytes and adipocytes: A potent negative regulator of adipocyte differentiation and proliferation of mammary carcinoma cells

Rahimi, N., Tremblay, E., McAdam, L. C., Roberts, A. B., & Elliott, B. E. (1998) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-998-0023-z · Cited by 57

Notch pathway is dispensable for adipocyte specification

Nichols, A. M., Pan, Y., Herreman, A., Hadland, B., Strooper, B. D., Kopan, R., & Huppert, S. S. (2004) · genesis · doi:10.1002/gene.20061 · Cited by 52

The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis

Guermah, M., Ge, K., Chiang, C., & Roeder, R. G. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00396-4 · Cited by 47

Developmental changes in thymidine kinase, DNA, and fat cellularity in Zucker rats.

Cleary, M. P., Brasel, J. A., & Greenwood, M. R. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.236.5.e508 · Cited by 42

New drugs from fat bugs?

Rosen, E. D. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2005.12.002 · Cited by 11

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

Hanahan, D., & Coussens, L. M. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.02.022 · Cited by 4,632

What we talk about when we talk about fat

Rosen, E. D., & Spiegelman, B. M. (2014) · Cell · doi:10.1016/j.cell.2013.12.012 · Cited by 2,373

Brown and beige fat: Development, function and therapeutic potential

Harms, M., & Seale, P. (2013) · Nature Medicine · doi:10.1038/nm.3361 · Cited by 2,328

Fat and Beyond: The Diverse Biology of PPARγ

Tontonoz, P., & Spiegelman, B. M. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.061307.091829 · Cited by 2,085

Adipose tissue dysfunction as determinant of obesity-associated metabolic complications

Longo, M., Zatterale, F., Naderi, J., Parrillo, L., Formisano, P., Raciti, G. A., Beguinot, F., & Miele, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092358 · Cited by 1,575

Adipocyte Differentiation

Moreno‐Navarrete, J. M., & Fernández‐Real, J. M. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0965-6_2 · Cited by 87

Transcriptional control of adipocyte formation

Farmer, S. R. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.07.001 · Cited by 1,836

Genes that integrate multiple adipogenic signaling pathways in human mesenchymal stem cells

Ito, T., Tsuruta, S., Tomita, K., Kikuchi, K., Yokoi, T., & Aizawa, Y. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.05.089 · Cited by 6

Forming functional fat: a growing understanding of adipocyte differentiation

Cristancho, A. G., & Lazar, M. A. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3198 · Cited by 1,382

Control of histone modifications

Davie, J., & Spencer, V. A. (1999) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(1999)75:32+ · Cited by 146