The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Systemic stress signalling: understanding the cell non-autonomous control of proteostasis
Open accessAbstract
Proteome maintenance is crucial to cellular health and viability, and is typically thought to be controlled in a cell-autonomous manner. However, recent evidence indicates that protein-folding defects can systemically activate proteostasis mechanisms through signalling pathways that coordinate stress responses among tissues. Coordination of ageing rates between tissues may also be mediated by systemic modulation of proteostasis. These findings suggest that proteome maintenance is a systemically regulated process, a discovery that may have important therapeutic implications.
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Citations
Cites
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Blackwell, T. K., Steinbaugh, M. J., Hourihan, J. M., Ewald, C. Y., & Isik, M. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.06.008 · Cited by 622
AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner
Ulgherait, M., Rana, A., Rera, M., Graniel, J., & Walker, D. W. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.006 · Cited by 306
Signaling networks determining life span
Riera, C. E., Merkwirth, C., De Magalhaes Filho, C. D., & Dillin, A. (2016) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060815-014451 · Cited by 161
Self-citationSystemic Nutrient and Stress Signaling via Myokines and Myometabolites
Rai, M., & Demontis, F. (2016) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105305 · Cited by 123
The hyaluronidase, TMEM2, promotes ER homeostasis and longevity independent of the UPRER
Schinzel, R. T., Higuchi-Sanabria, R., Shalem, O., Moehle, E. A., Webster, B. M., Joe, L., Bar-Ziv, R., Frankino, P. A., Durieux, J., Pender, C., et al. (2019) · Cell · doi:10.1016/j.cell.2019.10.018 · Cited by 117
Self-citation
Metadata
- Authors
- Taylor, R. C., Berendzen, K. M., & Dillin, A.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2014-02-21
- Volume
- 15
- Issue
- 3
- Pages
- 211-217
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W1986172762
- Cited by
- 175
- References
- 14
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- green
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