RNA targets of wild-type and mutant FET family proteins

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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

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Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

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RNA buffers the phase separation behavior of prion-like RNA binding proteins

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RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

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Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

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Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

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Defining the RGG/RG Motif

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The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

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Protein aggregation in amyotrophic lateral sclerosis

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RGG/RG Motif Regions in RNA Binding and Phase Separation

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Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

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Physiological functions and pathobiology of TDP ‐43 and FUS / TLS proteins

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HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients

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RBM5, 6, and 10 Differentially Regulate NUMB Alternative Splicing to Control Cancer Cell Proliferation

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ALS Genetics: Gains, Losses, and Implications for Future Therapies

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The role of FUS gene variants in neurodegenerative diseases

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Global analysis of yeast mRNPs

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Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization

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RNA stores tau reversibly in complex coacervates

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RNA Seeds Higher-Order Assembly of FUS Protein

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GraphProt: modeling binding preferences of RNA-binding proteins

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TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells

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Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

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Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)

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ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

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Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions

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The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis

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The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage

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Prediction of RNA-protein sequence and structure binding preferences using deep convolutional and recurrent neural networks

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A deep learning framework for modeling structural features of RNA-binding protein targets

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Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery

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FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2Preprint

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FUS stimulates microRNA biogenesis by facilitating co‐transcriptional Drosha recruitment

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Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding

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Biochemical Properties and Biological Functions of FET Proteins

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ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP

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RNA-binding proteins in neurodegeneration: mechanisms in aggregatePreprint

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Genetic mutations in RNA-binding proteins and their roles in ALS

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Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions

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Identification of RNA–protein interaction networks using PAR‐CLIP

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Paraspeckle formation during the biogenesis of long non-coding RNAs

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The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity

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ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation

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RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

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RNA Dysregulation in Amyotrophic Lateral Sclerosis

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PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage

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Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty

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Predicting RNA–protein binding sites and motifs through combining local and global deep convolutional neural networks

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FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress

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CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17

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Misregulated RNA processing in amyotrophic lateral sclerosis

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TDP ‐43 and FUS en route from the nucleus to the cytoplasm

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Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses

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Disrupted neuronal trafficking in amyotrophic lateral sclerosis

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Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

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Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways

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Resources for the Comprehensive Discovery of Functional RNA Elements

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Fused in sarcoma (FUS): An oncogene goes awry in neurodegeneration

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Emerging connections between RNA and autophagy

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Nucleic acid-binding specificity of human FUS protein

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RNA-Binding Proteins in Amyotrophic Lateral Sclerosis.

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Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads

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Functions of FUS/TLS From DNA Repair to Stress Response: Implications for ALS

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Position-specific binding of FUS to nascent RNA regulates mRNA lengthPreprint

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NY‐ESO‐1 is a ubiquitous immunotherapeutic target antigen for patients with myxoid/round cell liposarcoma

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Genome sequence–independent identification of RNA editing sites

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Phenotypic Heterogeneity of Monogenic Frontotemporal Dementia

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Orthogonal matrix factorization enables integrative analysis of multiple RNA binding proteins

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Minor intron splicing is regulated by FUS and affected by ALS‐associated FUS mutants

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Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging

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RNA-binding proteins in neurodegeneration: Seq and you shall receive

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Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2

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Structure–function studies of STAR family Quaking proteins bound to their in vivo RNA target sitesPreprint

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FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination

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FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns

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DeepCLIP: predicting the effect of mutations on protein–RNA binding with deep learning

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Role of FET proteins in neurodegenerative disorders

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Axonal transport defects are a common phenotype in Drosophila models of ALS

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Dysregulation of RNA-Binding Proteins in Amyotrophic Lateral Sclerosis

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Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

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Activity of sunitinib in extraskeletal myxoid chondrosarcoma

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RNA binding proteins and the pathological cascade in ALS/FTD neurodegeneration

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FUS Regulates Activity of MicroRNA-Mediated Gene Silencing

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PIPE-CLIP: a comprehensive online tool for CLIP-seq data analysis

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Amyotrophic Lateral Sclerosis associated FUS mutation shortens mitochondria and induces neurotoxicity

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RNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome

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U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish

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RNA Binding Proteins in the miRNA Pathway

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ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAsPreprint

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Functional characterization of the FET family of RNA-binding proteins

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FET proteins in frontotemporal dementia and amyotrophic lateral sclerosis

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Biochemical Properties and Biological Functions of FET Proteins

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FUS and TAF15 safeguard the critical functions of the ribonucleoprotein network formed by EWSR1 and newly synthesized RNAPreprint

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RNA metabolism in neurological disease

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