Tuschl, Thomas

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., & Tuschl, T. (2001) · Nature

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 9,456

Identification of Novel Genes Coding for Small Expressed RNAs

Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 4,956

Silencing of microRNAs in vivo with ‘antagomirs’

Krützfeldt, J., Rajewsky, N., Braich, R., Rajeev, K. G., Tuschl, T., Manoharan, M., & Stoffel, M. (2005) · Nature

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 3,949

Human MicroRNA Targets

John, B., Enright, A. J., Aravin, A., Tuschl, T., Sander, C., & Marks, D. S. (2004) · PLoS Biology

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 3,796

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing

Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., Pfeffer, S., Rice, A., Kamphorst, A. O., Landthaler, M., et al. (2007) · Cell

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 3,626

MicroRNA targets in Drosophila

Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 3,597

Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T. (2002) · Current Biology

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 3,355

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

Hafner, M., Landthaler, M., Burger, L., Khorshid, M., Hausser, J., Berninger, P., Rothballer, A., Ascano, M., Jungkamp, A.-C., Munschauer, M., et al. (2010) · Cell

RNA Research and SplicingRNA regulation and disease

Cited by 2,873

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

Hutvágner, G., McLachlan, J., Pasquinelli, A. E., Bálint, E., Tuschl, T., & Zamore, P. D. (2001) · Science

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 2,781

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

Thum, T., Gross, C., Fiedler, J., Fischer, T., Kissler, S., Bussen, M., Galuppo, P., Just, S., Rottbauer, W., Frantz, S., et al. (2008) · Nature

Cardiac Fibrosis and RemodelingMicroRNA in disease regulation

Cited by 2,349

A pancreatic islet-specific microRNA regulates insulin secretion

Poy, M. N., Eliasson, L., Krutzfeldt, J., Kuwajima, S., Ma, X., MacDonald, P. E., Pfeffer, S., Tuschl, T., Rajewsky, N., Rorsman, P., et al. (2004) · Nature

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 2,102

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G., & Tuschl, T. (2004) · Molecular Cell

RNA Interference and Gene DeliveryMicroRNA in disease regulation

Cited by 2,052

A census of human RNA-binding proteins

Gerstberger, S., Hafner, M., & Tuschl, T. (2014) · Nature Reviews Genetics

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 2,032

A novel class of small RNAs bind to MILI protein in mouse testes

Aravin, A., Gaidatzis, D., Pfeffer, S., Lagos-Quintana, M., Landgraf, P., Iovino, N., Morris, P., Brownstein, M. J., Kuramochi-Miyagawa, S., Nakano, T., et al. (2006) · Nature

Sperm and Testicular FunctionChromosomal and Genetic Variations

Cited by 1,516

Cyclic [G(2′,5′)pA(3′,5′)p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.

Gao, P., Ascano, M., Wu, Y., Barchet, W., Gaffney, B. L., Zillinger, T., Serganov, A. A., Liu, Y., Jones, R. A., Hartmann, G., et al. (2013) · Cell

interferon and immune responsesPhosphodiesterase function and regulation

Cited by 1,101

New microRNAs from mouse and human

LAGOS-QUINTANA, M., RAUHUT, R., MEYER, J., BORKHARDT, A., & TUSCHL, T. (2003) · RNA

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 909

Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy

Paludan, C., Schmid, D., Landthaler, M., Vockerodt, M., Kube, D., Tuschl, T., & Münz, C. (2005) · Science

Autophagy in Disease and TherapyImmunotherapy and Immune Responses

Cited by 860

FMRP targets distinct mRNA sequence elements to regulate protein expression

Ascano, M., Mukherjee, N., Bandaru, P., Miller, J. B., Nusbaum, J. D., Corcoran, D. L., Langlois, C., Munschauer, M., Dewell, S., Hafner, M., et al. (2012) · Nature

Genetics and Neurodevelopmental DisordersRNA Research and Splicing

Cited by 701

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

Mukherjee, N., Corcoran, D. L., Nusbaum, J. D., Reid, D. W., Georgiev, S., Hafner, M., Ascano, M., Tuschl, T., Ohler, U., & Keene, J. D. (2011) · Molecular Cell

RNA Research and SplicingRNA regulation and disease

Cited by 654

Sequence, Chemical, and Structural Variation of Small Interfering RNAs and Short Hairpin RNAs and the Effect on Mammalian Gene Silencing

Harborth, J., Elbashir, S. M., Vandenburgh, K., Manninga, H., Scaringe, S. A., Weber, K., & Tuschl, T. (2003) · Antisense and Nucleic Acid Drug Development

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 474

Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB

Rajasethupathy, P., Fiumara, F., Sheridan, R., Betel, D., Puthanveettil, S. V., Russo, J. J., Sander, C., Tuschl, T., & Kandel, E. (2009) · Neuron

Neuroscience and Neuropharmacology ResearchMicroRNA in disease regulation

Cited by 406

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Der, E., Suryawanshi, H., Morozov, P., Kustagi, M., Goilav, B., Ranabothu, S., Izmirly, P., Clancy, R., Belmont, H. M., et al. (2019) · Nature Immunology

Systemic Lupus Erythematosus ResearchRenal Diseases and Glomerulopathies

Cited by 403

RNA targets of wild-type and mutant FET family proteins

Hoell, J. I., Larsson, E., Runge, S., Nusbaum, J. D., Duggimpudi, S., Farazi, T. A., Hafner, M., Borkhardt, A., Sander, C., & Tuschl, T. (2011) · Nature Structural & Molecular Biology

RNA Research and SplicingAmyotrophic Lateral Sclerosis Research

Cited by 350

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lama, L., Adura, C., Xie, W., Tomita, D., Kamei, T., Kuryavyi, V., Gogakos, T., Steinberg, J. I., Miller, M., Ramos-Espiritu, L., et al. (2019) · Nature Communications

interferon and immune responsesPhosphodiesterase function and regulation

Cited by 303