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Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors

Liu, Dawei, Kou, Xiaoxing, Chen, Chider, Liu, Shiyu, Liu, Yao, Yu, Wenjing, Yu, Tingting, Yang, Ruili, Wang, Runci, Zhou, Yanheng, Shi, Songtao·2018·Cell Research
DOI 10.1038/s41422-018-0070-2
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  1. Kerr, J. F., Wyllie, A. H. & Currie, A. R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239–257 (1972). · DOI
  2. Bergmann, A. & Steller, H. Apoptosis, stem cells, and tissue regeneration. Sci. Signal 3, re8 (2010). · DOI
  3. Davidson, F. F. & Steller, H. Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants. Nature 391, 587–591 (1998). · DOI
  4. Hochreiter-Hufford, A. E. et al. Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion. Nature 497, 263–267 (2013). · DOI
  5. Pellettieri, J. & Sanchez Alvarado, A. Cell turnover and adult tissue homeostasis: from humans to planarians. Annu. Rev. Genet. 41, 83–105 (2007). · DOI
  6. Arandjelovic, S. & Ravichandran, K. S. Phagocytosis of apoptotic cells in homeostasis. Nat. Immunol. 16, 907–917 (2015). · DOI · Paper page
  7. Radi, E., Formichi, P., Battisti, C. & Federico, A. Apoptosis and oxidative stress in neurodegenerative diseases. J. Alzheimers Dis. 42(Suppl 3), S125–S152 (2014). · DOI
  8. Nagata, S. Apoptosis and autoimmune diseases. Ann. N. Y. Acad. Sci. 1209, 10–16 (2010). · DOI
  9. Cheng, J. et al. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 263, 1759–1762 (1994). · DOI
  10. Bergsmedh, A. et al. Horizontal transfer of oncogenes by uptake of apoptotic bodies. Proc. Natl Acad. Sci. USA 98, 6407–6411 (2001). · DOI · Paper page
  11. Zernecke, A. et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci. Signal. 2, ra81 (2009). · DOI
  12. Nawaz, M. et al. Extracellular vesicles: evolving factors in stem cell biology. Stem Cells Int. 2016, 1073140 (2016). · DOI
  13. Juncadella, I. J. et al. Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation. Nature 493, 547–551 (2013). · DOI
  14. Elliott, M. R. & Ravichandran, K. S. The dynamics of apoptotic cell clearance. Dev. Cell 38, 147–160 (2016). · DOI
  15. Elliott, M. R. et al. Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo. Nature 467, 333–337 (2010). · DOI
  16. Weavers, H., Evans, I. R., Martin, P. & Wood, W. Corpse engulfment generates a molecular memory that primes the macrophage inflammatory response. Cell 165, 1658–1671 (2016). · DOI
  17. Friedenstein, A. J., Chailakhyan, R. K., Latsinik, N. V., Panasyuk, A. F. & Keiliss-Borok, I. V. Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues: cloning in vitro and retransplantation in vivo. Transplantation 17, 331–340 (1974). · DOI
  18. Prockop, D. J. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276, 71–74 (1997). · DOI
  19. Shi, S. et al. Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nat. Biotechnol. 20, 587–591 (2002). · DOI
  20. Shi, S. & Gronthos, S. Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. J. Bone Mineral. Res. 18, 696–704 (2003). · DOI
  21. Liu, Y. et al. Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-gamma and TNF-alpha. Nat. Med. 17, 1594–1601 (2011). · DOI
  22. Sun, L. et al. Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans. Stem Cells 27, 1421–1432 (2009). · DOI
  23. Le Blanc, K. et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363, 1439–1441 (2004). · DOI · Paper page
  24. Ren, G. et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell stem Cell 2, 141–150 (2008). · DOI · Paper page
  25. Uccelli, A., Pistoia, V. & Moretta, L. Mesenchymal stem cells: a new strategy for immunosuppression? Trends Immunol. 28, 219–226 (2007). · DOI
  26. Drappa, J., Brot, N. & Elkon, K. B. The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr. Proc. Natl Acad. Sci. USA 90, 10340–10344 (1993). · DOI
  27. Chu, J. L., Drappa, J., Parnassa, A. & Elkon, K. B. The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn. J. Exp. Med. 178, 723–730 (1993). · DOI
  28. Adachi, M., Watanabe-Fukunaga, R. & Nagata, S. Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc. Natl Acad. Sci. USA 90, 1756–1760 (1993). · DOI
  29. Buzas, E. I., Gyorgy, B., Nagy, G., Falus, A. & Gay, S. Emerging role of extracellular vesicles in inflammatory diseases. Nat. Rev. Rheumatol. 10, 356–364 (2014). · DOI
  30. E. L. A., S., Mager, I., Breakefield, X. O. & Wood, M. J. Extracellular vesicles: biology and emerging therapeutic opportunities. Nat. Rev. Drug Discov. 12, 347–357 (2013). · DOI · Paper page
  31. Crescitelli, R. et al. Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes. J. Extracell. Vesicles 2, 20677 (2013). · DOI · Paper page
  32. Hristov, M., Erl, W., Linder, S. & Weber, P. C. Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro. Blood 104, 2761–2766 (2004). · DOI
  33. Jayachandran, M., Miller, V. M., Heit, J. A. & Owen, W. G. Methodology for isolation, identification and characterization of microvesicles in peripheral blood. J. Immunol. Methods 375, 207–214 (2012). · DOI
  34. Miura, M. et al. A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. J. Clin. Investig. 114, 1704–1713 (2004). · DOI
  35. Liu, S. et al. MSC transplantation improves osteopenia via epigenetic regulation of notch signaling in lupus. Cell Metab. 22, 606–618 (2015). · DOI
  36. Belmokhtar, C. A., Hillion, J. & Segal-Bendirdjian, E. Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. Oncogene 20, 3354–3362 (2001). · DOI
  37. Zhang, X. D., Gillespie, S. K. & Hersey, P. Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways. Mol. Cancer Ther. 3, 187–197 (2004). · DOI
  38. Penberthy, K. K. & Ravichandran, K. S. Apoptotic cell recognition receptors and scavenger receptors. Immunol. Rev. 269, 44–59 (2016). · DOI
  39. Huang, S. M. et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461, 614–620 (2009). · DOI
  40. DaRosa, P. A. et al. Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal. Nature 517, 223–226 (2015). · DOI
  41. Zhang, Y. et al. RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling. Nat. Cell Biol. 13, 623–629 (2011). · DOI
  42. Kim, S. & Jho, E. H. The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2). J. Biol. Chem. 285, 36420–36426 (2010). · DOI
  43. Lui, T. T. et al. The ubiquitin-specific protease USP34 regulates axin stability and Wnt/beta-catenin signaling. Mol. Cell Biol. 31, 2053–2065 (2011). · DOI
  44. Xie, H. et al. PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis. Nat. Med. 20, 1270–1278 (2014). · DOI · Paper page
  45. Wang, X. et al. miR-214 targets ATF4 to inhibit bone formation. Nat. Med. 19, 93–100 (2013). · DOI
  46. Wang, L. et al. Osteoblast-induced osteoclast apoptosis by fas ligand/FAS pathway is required for maintenance of bone mass. Cell Death Differ. 22, 1654–1664 (2015). · DOI
  47. Chen, C. et al. Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. EMBO Mol. Med. 6, 322–334 (2014). · DOI
  48. Weissman, I. L. Stem cells are units of natural selection for tissue formation, for germline development, and in cancer development. Proc. Natl Acad. Sci. USA 112, 8922–8928 (2015). · DOI
  49. Li, F. et al. Apoptotic cells activate the “phoenix rising” pathway to promote wound healing and tissue regeneration. Sci. Signal 3, ra13 (2010).
  50. Lotvall, J. et al. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. J. Extracell. Vesicles 3, 26913 (2014). · DOI · Paper page
  51. Julian, L. & Olson, M. F. Apoptotic membrane dynamics in health and disease. Cell Health Cytoskelet. 7, 133–142 (2015).
  52. Mesa, K. R. et al. Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature 522, 94–97 (2015). · DOI
  53. Semon, J. A. et al. Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels. Cell Tissue Res. 341, 147–158 (2010). · DOI
  54. Bernardo, M. E. & Fibbe, W. E. Mesenchymal stromal cells: sensors and switchers of inflammation. Cell Stem Cell 13, 392–402 (2013). · DOI
  55. Shi, Y. et al. How mesenchymal stem cells interact with tissue immune responses. Trends Immunol. 33, 136–143 (2012). · DOI
  56. Uccelli, A., Moretta, L. & Pistoia, V. Mesenchymal stem cells in health and disease. Nat. Rev. Immunol. 8, 726–736 (2008). · DOI
  57. Woo, M. et al. Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity. Nat. Immunol. 4, 1016–1022 (2003). · DOI
  58. Grootaert, M. O. et al. Caspase-3 deletion promotes necrosis in atherosclerotic plaques of ApoE knockout mice. Oxid. Med. Cell Longev. 2016, 3087469 (2016). · DOI
  59. Ling, L., Nurcombe, V. & Cool, S. M. Wnt signaling controls the fate of mesenchymal stem cells. Gene 433, 1–7 (2009). · DOI
  60. Boland, G. M., Perkins, G., Hall, D. J. & Tuan, R. S. Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells. J. Cell Biochem. 93, 1210–1230 (2004). · DOI
  61. Cho, H. H. et al. Endogenous Wnt signaling promotes proliferation and suppresses osteogenic differentiation in human adipose derived stromal cells. Tissue Eng. 12, 111–121 (2006). · DOI
  62. Baksh, D., Boland, G. M. & Tuan, R. S. Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation. J. Cell. Biochem. 101, 1109–1124 (2007). · DOI
  63. Baksh, D. & Tuan, R. S. Canonical and non-canonical Wnts differentially affect the development potential of primary isolate of human bone marrow mesenchymal stem cells. J. Cell Physiol. 212, 817–826 (2007). · DOI
  64. Bennett, C. N. et al. Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc. Natl Acad. Sci. USA 102, 3324–3329 (2005). · DOI
  65. Creemers, E. E., Tijsen, A. J. & Pinto, Y. M. Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease? Circ. Res. 110, 483–495 (2012). · DOI
  66. Mazzoni, S. M. & Fearon, E. R. AXIN1 and AXIN2 variants in gastrointestinal cancers. Cancer Lett. 355, 1–8 (2014). · DOI
  67. Gennarino, V. A. et al. Identification of microRNA-regulated gene networks by expression analysis of target genes. Genome Res. 22, 1163–1172 (2012). · DOI
  68. Chhabra, R., Adlakha, Y. K., Hariharan, M., Scaria, V. & Saini, N. Upregulation of miR-23a-27a-24-2 cluster induces caspase-dependent and -independent apoptosis in human embryonic kidney cells. PLoS ONE 4, e5848 (2009). · DOI
  69. Akiyama, K. et al. Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis. Cell Stem Cell 10, 544–555 (2012). · DOI
  70. Kaiser, J. Aging ‘Rejuvenation factor’ in blood turns back the clock in old mice. Science 344, 570–571 (2014). · DOI
  71. Bitto, A. & Kaeberlein, M. Rejuvenation: it’s in our blood. Cell Metab. 20, 2–4 (2014). · DOI

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Metadata

Authors
Liu, D., Kou, X., Chen, C., Liu, S., Liu, Y., Yu, W., Yu, T., Yang, R., Wang, R., Zhou, Y., & Shi, S.
Venue
Cell Research
Publisher
Springer Science and Business Media LLC
Published
2018-07-20
Volume
28
Issue
9
Pages
918-933
ISSN
  • 1001-0602
  • 1748-7838
DOI
10.1038/s41422-018-0070-2
Cited by
298
References
13
Language
en
Licence
www.springer.com/tdm (tdm)

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