The DOI matches its Crossref record; 10 of the 11 references it cites were found in a registry or an index.
Functional exhaustion of antiviral lymphocytes in COVID-19 patients
Open accessAbstract
In December 2019, a novel coronavirus was first reported in Wuhan, China. 1 It was named by the World Health Organization as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is responsible for coronavirus disease 2019 (COVID-19). Up to 28 February 2020, 79,394 cases have been confirmed according to China’s National Health Commission. Outside China, the virus has spread rapidly to over 36 countries and territories.
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“In ex vivo studies, NK cells from patients with COVID-19 displayed impaired cytotoxicity (64, 65)”
From SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients (2021) · cites this paper as [64]
In the citing paper
“NK cells were shown to be decreased in patients with COVID-19 in association with disease severity (64).”
From SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients (2021) · cites this paper as [64]
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Cites
A novel coronavirus from patients with pneumonia in China, 2019
Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001017 · Cited by 28,244
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Zhou, P., Yang, X.-L., Wang, X.-G., Hu, B., Zhang, L., Zhang, W., Si, H.-R., Zhu, Y., Li, B., Huang, C.-L., et al. (2020) · Nature · doi:10.1038/s41586-020-2012-7 · Cited by 21,969
Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30211-7 · Cited by 21,415
Restoring function in exhausted CD8 T cells during chronic viral infection
Barber, D. L., Wherry, E. J., Masopust, D., Zhu, B., Allison, J. P., Sharpe, A. H., Freeman, G. J., & Ahmed, R. (2005) · Nature · doi:10.1038/nature04444 · Cited by 4,057
André, P., Denis, C., Soulas, C., Bourbon, C., Lopez, J., Arnoux, T., Bléry, M., Bonnafous, C., Gauthier, L., Morel, A., et al. (2018) · Cell · doi:10.1016/j.cell.2018.10.014 · Cited by 1,257
Zhang, Q., Bi, J., Zheng, X., Chen, Y., Wang, H., Wu, W., Wang, Z., Wu, Q., Peng, H. C., Wei, H., et al. (2018) · Nature Immunology · doi:10.1038/s41590-018-0132-0 · Cited by 1,155
Self-citationLi, F., Wei, H., Wei, H., Gao, Y., Xu, L., Yin, W., Sun, R., & Tian, Z. (2013) · Gastroenterology · doi:10.1053/j.gastro.2012.10.039 · Cited by 164
Self-citationNKG2A is a NK cell exhaustion checkpoint for HCV persistence
Zhang, C., Wang, X., Li, S.-R., Twelkmeyer, T., Wang, W., Zhang, S.-Y., Wang, S., Chen, J., Jin, X., Wu, Y., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09212-y · Cited by 148
NKG2A, a New Kid on the Immune Checkpoint Block
Haanen, J. B. A. G., & Cerundolo, V. (2018) · Cell · doi:10.1016/j.cell.2018.11.048 · Cited by 104
Barathan, M., Mohamed, R., Yong, Y. K., Kannan, M., Vadivelu, J., Saeidi, A., Larsson, M., & Shankar, E. M. (2018) · Cells · doi:10.3390/cells7100165 · Cited by 37
Cited by
Sorted by citations
COVID-19 pathophysiology: A review
Yuki, K., Shibamura‐Fujiogi, M., & Koutsogiannaki, S. (2020) · Clinical Immunology · doi:10.1016/j.clim.2020.108427 · Cited by 2,286
“COVID-19 has been impacting a large number of people worldwide, being reported in approximately 200 countries and territories [3,4].”
Cytokine release syndrome in severe COVID-19
Moore, J. B., & June, C. H. (2020) · Science · doi:10.1126/science.abb8925 · Cited by 1,912
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine, T., Perez-Potti, A., Rivera-Ballesteros, O., Strålin, K., Gorin, J.-B., Olsson, A., Llewellyn-Lacey, S., Kamal, H., Bogdanovic, G., Muschiol, S., et al. (2020) · Cell · doi:10.1016/j.cell.2020.08.017 · Cited by 1,788
McGonagle, D., Sharif, K., O'Regan, A., & Bridgewood, C. (2020) · Autoimmunity Reviews · doi:10.1016/j.autrev.2020.102537 · Cited by 1,654
“A characteristic feature of primary HLH but not sHLH/MAS is defective NK function which is also reported in COVID-19 infection, but by different mechanisms [40] .”
BackgroundCOVID-19: immunopathology and its implications for therapy
Cao, X. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0308-3 · Cited by 1,609
Metadata
- Authors
- Zheng, M., Gao, Y., Wang, G., Song, G., Liu, S., Sun, D., Xu, Y., & Tian, Z.
- Affiliations
- First Affiliated Hospital of Anhui Medical University (CN)
- Anhui Medical University (CN)
- University of Science and Technology of China (CN)
- Corresponding author
- Zheng, Meijuan
- Xu, Yuanhong
- Tian, Zhigang
- Venue
- Cellular & Molecular Immunology
- Published
- 2020-03-19
- Volume
- 17
- Issue
- 5
- Pages
- 533-535
- ISSN
- 1672-7681 (ISSN-L)
- 2042-0226
- PMC
- PMC7091858
- OpenAlex
- W3011508332
- Cited by
- 1,768
- References
- 11
- Citations by year
- 2026: 26 · 2025: 63 · 2024: 119 · 2023: 186 · 2022: 329 · 2021: 514 · 2020: 531
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Cellular and Molecular Immunology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (81788101, 81771685)
- Chinese Academy of Sciences (XDB29030000, 81788101)
- Anhui Medical University (YJGG202002)
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- COVID-19 pandemic, SARS-CoV-2, T cell exhaustion, T cell dysfunction
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Antiviral Agents, Hepatitis C, Humans, Killer Cells, Natural, Pneumonia, Viral, Coronavirus Infections, Pandemics
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