SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress
Open accessPublished version of a preprint
Abstract
Enduring behavioral changes upon stress exposure involve changes in gene expression sustained by epigenetic modifications in brain circuits, including the mesocorticolimbic pathway. Brahma (BRM) and Brahma Related Gene 1 (BRG1) are ATPase subunits of the SWI/SNF complexes involved in chromatin remodeling, a process essential to enduring plastic changes in gene expression. Here, we show that in mice, social defeat induces changes in BRG1 nuclear distribution. The inactivation of the Brg1/Smarca4 gene within dopamine-innervated regions or the constitutive inactivation of the Brm/Smarca2 gene leads to resilience to repeated social defeat and decreases the behavioral responses to cocaine without impacting midbrain dopamine neurons activity. Within striatal medium spiny neurons, Brg1 gene inactivation reduces the expression of stress- and cocaine-induced immediate early genes, increases levels of heterochromatin and at a global scale decreases chromatin accessibility. Altogether these data demonstrate the pivotal function of SWI/SNF complexes in behavioral and transcriptional adaptations to salient environmental challenges.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Inactivation of the ATPase subunit of the SWI/SNF complexes, Brahma Related Gene 1, reduces the expression of stress- and cocaine-induced immediate early genes, increases heterochromatin levels, and generally reduces chromatin accessibility in striatal medium spiny neurons.
“The inactivation of ATPase subunit of the SWI/SNF complexes, Brahma Related Gene 1, reduces the expression of stress- and cocaine-induced immediate early genes, increases heterochromatin levels, and generally reduces chromatin accessibility in striatal medium spiny neurons.379”
From Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential (2023) · cites this paper as [379]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Buenrostro, J. D., Giresi, P. G., Zaba, L. C., Chang, H. Y., & Greenleaf, W. J. (2013) · Nature Methods · doi:10.1038/nmeth.2688 · Cited by 6,422 · see citing works
Stress and the brain: from adaptation to disease
de Kloet, E. R., Joëls, M., & Holsboer, F. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1683 · Cited by 4,621 · see citing works
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
Berton, O., McClung, C. A., DiLeone, R. J., Krishnan, V., Renthal, W., Russo, S. J., Graham, D., Tsankova, N. M., Bolanos, C. A., Rios, M., et al. (2006) · Science · doi:10.1126/science.1120972 · Cited by 2,129 · see citing works
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
Tsankova, N. M., Berton, O., Renthal, W., Kumar, A., Neve, R. L., & Nestler, E. J. (2006) · Nature Neuroscience · doi:10.1038/nn1659 · Cited by 1,780 · see citing works
Patterns and rates of exonic de novo mutations in autism spectrum disorders
Neale, B. M., Kou, Y., Liu, L., Ma’ayan, A., Samocha, K. E., Sabo, A., Lin, C.-F., Stevens, C., Wang, L.-S., Makarov, V., et al. (2012) · Nature · doi:10.1038/nature11011 · Cited by 1,734 · see citing works
Dynamic DNA methylation programs persistent adverse effects of early-life stress
Murgatroyd, C., Patchev, A. V., Wu, Y., Micale, V., Bockmühl, Y., Fischer, D., Holsboer, F., Wotjak, C. T., Almeida, O. F. X., & Spengler, D. (2009) · Nature Neuroscience · doi:10.1038/nn.2436 · Cited by 1,162 · see citing works
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons
Chaudhury, D., Walsh, J. J., Friedman, A. K., Juarez, B., Ku, S. M., Koo, J. W., Ferguson, D., Tsai, H.-C., Pomeranz, L., Christoffel, D. J., et al. (2013) · Nature · doi:10.1038/nature11713 · Cited by 1,156 · see citing works
Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression
van Steensel, B., & Belmont, A. S. (2017) · Cell · doi:10.1016/j.cell.2017.04.022 · Cited by 1,140 · see citing works
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms
Hargreaves, D. C., & Crabtree, G. R. (2011) · Cell Research · doi:10.1038/cr.2011.32 · Cited by 923 · see citing works
A Brg1 Null Mutation in the Mouse Reveals Functional Differences among Mammalian SWI/SNF Complexes
Bultman, S. J., Gebuhr, T., Yee, D., LaMantia, C., Nicholson, J., Gilliam, A. C., Randazzo, F. M., METZGER, D., Chambon, P., Crabtree, G. R., et al. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00127-1 · Cited by 824 · see citing works
Antidepressant Actions of Histone Deacetylase Inhibitors
Covington, H. E., Maze, I., LaPlant, Q. C., Vialou, V. F., Ohnishi, Y. N., Berton, O., Fass, D. M., Renthal, W., Rush, A. J., Wu, E. Y., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1758-09.2009 · Cited by 624 · see citing works
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
LaPlant, Q., Vialou, V., Covington, H. E., Dumitriu, D., Feng, J., Warren, B. L., Maze, I., Dietz, D. M., Watts, E. L., Iñiguez, S. D., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2619 · Cited by 612 · see citing works
Muchardt, C., & Yaniv, M. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06112.x · Cited by 588 · see citing works
Self-citationInvolvement of the Extracellular Signal-Regulated Kinase Cascade for Cocaine-Rewarding Properties
Valjent, E., Corvol, J., Pagès, C., Besson, M., Maldonado, R. J., & Caboche, J. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-23-08701.2000 · Cited by 548 · see citing works
Antidepressant-Like Effects of the Histone Deacetylase Inhibitor, Sodium Butyrate, in the Mouse
Schroeder, F. A., Lin, C. L., Crusio, W. E., & Akbarian, S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.06.036 · Cited by 541 · see citing works
Sinha, R., Garcia, M., Paliwal, P., Kreek, M. J., & Rounsaville, B. J. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.3.324 · Cited by 528 · see citing works
Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome
Tsurusaki, Y., Okamoto, N., Ohashi, H., Kosho, T., Imai, Y., Hibi‐Ko, Y., Kaname, T., Naritomi, K., Kawame, H., Wakui, K., et al. (2012) · Nature Genetics · doi:10.1038/ng.2219 · Cited by 518 · see citing works
Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex
Fryer, C. J., & Archer, T. K. (1998) · Nature · doi:10.1038/30032 · Cited by 511 · see citing works
Genome-wide epigenetic regulation by early-life trauma
Labonté, B., Suderman, M., Maussion, G., Navaro, L., Yerko, V., Mahar, I., Bureau, A., Mechawar, N., Szyf, M., Meaney, M. J., et al. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.2287 · Cited by 488 · see citing works
ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses
Vialou, V., Robison, A. J., LaPlant, Q. C., Covington, H. E., Dietz, D. M., Ohnishi, Y. N., Mouzon, E., Rush, A. J., Watts, E. L., Wallace, D. L., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2551 · Cited by 479 · see citing works
The human glucocorticoid receptor: molecular basis of biologic function
Nicolaides, N. C., Galata, Z., Kino, T., Chrousos, G. P., & Charmandari, E. (2010) · Steroids · doi:10.1016/j.steroids.2009.09.002 · Cited by 436 · see citing works
Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)
Reyes, J. C., Barra, J., Muchardt, C., Camus, A., Babinet, C., & Yaniv, M. (1998) · The EMBO Journal · doi:10.1093/emboj/17.23.6979 · Cited by 433 · see citing works
Self-citationInteraction between glucocorticoid hormones, stress and psychostimulant drugs*
Marinelli, M., & Piazza, P. V. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02089.x · Cited by 426 · see citing works
Rapid non-genomic effects of corticosteroids and their role in the central stress response
Groeneweg, F. L., Karst, H., de Kloet, E. R., & Joëls, M. (2011) · Journal of Endocrinology · doi:10.1530/joe-10-0472 · Cited by 414 · see citing works
Ratman, D., Vanden Berghe, W., Dejager, L., Libert, C., Tavernier, J., Beck, I. M., & De Bosscher, K. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.12.014 · Cited by 411 · see citing works
Cao, J.-L., Covington, H. E., Friedman, A. K., Wilkinson, M. B., Walsh, J. J., Cooper, D. C., Nestler, E. J., & Han, M.-H. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.3177-10.2010 · Cited by 402 · see citing works
Inhibition of mediodorsal thalamus disrupts thalamofrontal connectivity and cognition
Parnaudeau, S., O’Neill, P.-K., Bolkan, S. S., Ward, R. D., Abbas, A. I., Roth, B. L., Balsam, P. D., Gordon, J. A., & Kellendonk, C. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.038 · Cited by 387 · see citing works
Self-citationRegulation of Dendritic Development by Neuron-Specific Chromatin Remodeling Complexes
Wu, J. I., Lessard, J. A., Olave, I. A., Qiu, Z., Ghosh, A., Graef, I. A., & Crabtree, G. R. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.021 · Cited by 384 · see citing works
Melia, K. R., Ryabinin, A. E., Schroeder, R., Bloom, F. E., & Wilson, M. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-10-05929.1994 · Cited by 359 · see citing works
Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome
Santen, G. W. E., Aten, E., Sun, Y., Almomani, R., Gilissen, C., Nielsen, M., Kant, S. G., Snoeck, I. N., Peeters, E. A. J., Hilhorst-Hofstee, Y., et al. (2012) · Nature Genetics · doi:10.1038/ng.2217 · Cited by 347 · see citing works
Epigenetic basis of mental illness
Nestler, E. J., Peña, C. J., Kundakovic, M., Mitchell, A., & Akbarian, S. (2016) · The Neuroscientist · doi:10.1177/1073858415608147 · Cited by 342 · see citing works
Interaction of the Glucocorticoid Receptor with the Chromatin Landscape
John, S., Sabo, P. J., Johnson, T. A., Sung, M., Biddie, S. C., Lightman, S. L., Voss, T. C., Davis, S. R., Meltzer, P. S., Stamatoyannopoulos, J. A., et al. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.02.010 · Cited by 311 · see citing works
A Specificity and Targeting Subunit of a Human SWI/SNF Family-Related Chromatin-Remodeling Complex
Nie, Z., Xue, Y., Yang, D., Zhou, S., Deroo, B. J., Archer, T., & Wang, W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.23.8879-8888.2000 · Cited by 298 · see citing works
Brami‐Cherrier, K., Valjent, E., Hervé, D., Darragh, J., Corvol, J., Pagès, C., Simon, A. J., Girault, J., & Caboche, J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1711-05.2005 · Cited by 294 · see citing works
A Role for Repressive Histone Methylation in Cocaine-Induced Vulnerability to Stress
Covington, H. E., Maze, I., Sun, H., Bomze, H. M., DeMaio, K. D., Wu, E. Y., Dietz, D. M., Lobo, M. K., Ghose, S., Mouzon, E., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.007 · Cited by 289 · see citing works
Cosma, M. P. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00604-4 · Cited by 261 · see citing works
Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome
Houdt, J. K. J. V., Nowakowska, B., de Sousa, S. B., van Schaik, B. D. C., Seuntjens, E., Avonce, N., Sifrim, A., Abdul-Rahman, O. A., van den Boogaard, M. H., Bottani, A., et al. (2012) · Nature Genetics · doi:10.1038/ng.1105 · Cited by 239 · see citing works
Ciernia, A. V., Matheos, D. P., Barrett, R. M., Kramár, E. A., Azzawi, S., Chen, Y., Magnan, C. N., Zeller, M. D., Sylvain, A. S., Häettig, J., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3359 · Cited by 234 · see citing works
Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
Zhang, H., Pandey, S., Travers, M. E., Sun, H., Morton, G. C., Madžo, J., Chung, W., Khowsathit, J., Pérez, Ó. C., Barrero, C. A., et al. (2018) · Cell · doi:10.1016/j.cell.2018.09.051 · Cited by 218 · see citing works
Chronic stress triggers social aversion via glucocorticoid receptor in dopaminoceptive neurons
Barik, J., Marti, F., Morel, C., Fernandez, S. P., Lanteri, C., Godeheu, G., Tassin, J.-P., Mombereau, C., Faure, P., & Tronche, F. (2013) · Science · doi:10.1126/science.1226767 · Cited by 214 · see citing works
Self-citationGenome-Wide Methylation Changes in the Brains of Suicide Completers
Labonté, B., Suderman, M., Maussion, G., Lopez, J. P., Navarro-Sánchez, L., Yerko, V., Mechawar, N., Szyf, M., Meaney, M. J., & Turecki, G. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12050627 · Cited by 212 · see citing works
Inducible site-specific recombination in the brain 1 1Edited by M. Yaniv
Kellendonk, C., Tronche, F., Casanova, E., Anlag, K., Opherk, C., & Schütz, G. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.2307 · Cited by 206 · see citing works
Self-citationHsiao, P., Fryer, C. J., Trotter, K. W., Wang, W., & Archer, T. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.17.6210-6220.2003 · Cited by 202 · see citing works
Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking
Ambroggi, F., Turiault, M., Milet, A., Deroche‐Gamonet, V., Parnaudeau, S., Balado, É., Barik, J., van der Veen, R., Maroteaux, G., Lemberger, T., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2282 · Cited by 182 · see citing works
Self-citationKundaković, M., Lim, S. C., Gudsnuk, K. M., & Champagne, F. A. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00078 · Cited by 172 · see citing works
Nmezi, B., Xu, J., Fu, R., Armiger, T. J., Bey, G. R., Powell, J. S., Ma, H., Sullivan, M. L. G., Tu, Y., Chen, N. Y., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1810070116 · Cited by 166 · see citing works
Activation of Erk and JNK MAPK pathways by acute swim stress in rat brain regions
Shen, C., Tsimberg, Y., Salvadore, C., & Meller, E. (2004) · BMC Neuroscience · doi:10.1186/1471-2202-5-36 · Cited by 161 · see citing works
Drobic, B., Pérez-Cadahía, B., Yu, J., Kung, S. K. P., & Davie, J. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq030 · Cited by 149 · see citing works
c-Fos Facilitates the Acquisition and Extinction of Cocaine-Induced Persistent Changes
Zhang, J., Zhang, L., Jiao, H., Zhang, Q., Zhang, D., Lou, D., Katz, J. L., & Xu, M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3795-06.2006 · Cited by 146 · see citing works
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Strom, A. R., Biggs, R. J., Banigan, E. J., Wang, X., Chiu, K., Herman, C., Collado, J., Yue, F., Politz, J. C. R., Tait, L. J., et al. (2021) · eLife · doi:10.7554/elife.63972 · Cited by 144 · see citing works
Levine, A. A., Worrell, T. R., Zimnisky, R. M., & Schmauss, C. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.09.005 · Cited by 128 · see citing works
Pascoli, V., Besnard, A., Hervé, D., Pagès, C., Heck, N., Girault, J., Caboche, J., & Vanhoutte, P. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.08.031 · Cited by 126 · see citing works
Self-citationRbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly
Jacko, M., Weyn‐Vanhentenryck, S. M., Smerdon, J. W., Yan, R., Feng, H., Williams, D. J., Pai, J. A., Xu, K., Wichterle, H., & Zhang, C. (2018) · Neuron · doi:10.1016/j.neuron.2018.01.020 · Cited by 126 · see citing works
A Calcium-Dependent Switch in a CREST-BRG1 Complex Regulates Activity-Dependent Gene Expression
Qiu, Z., & Ghosh, A. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.040 · Cited by 125 · see citing works
Opposing Role for Egr3 in Nucleus Accumbens Cell Subtypes in Cocaine Action
Chandra, R., Francis, T. C., Konkalmatt, P. R., Amgalan, A., Gancarz, A. M., Dietz, D., & Lobo, M. K. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0548-15.2015 · Cited by 124 · see citing works
Plasticity-Associated GeneKrox24/Zif268Is Required for Long-Lasting Behavioral Effects of Cocaine
Valjent, E., Aubier, B., Corbillé, A.-G., Brami‐Cherrier, K., Caboche, J., Topilko, P., Girault, J., & Hervé, D. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4601-05.2006 · Cited by 121 · see citing works
Indra, A. K., Dupé, V., Bornert, J., Messaddeq, N., Yaniv, M., Mark, M. P., Chambon, P., & METZGER, D. (2005) · Development · doi:10.1242/dev.02019 · Cited by 116 · see citing works
Self-citationInvolvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia
Koga, M., Ishiguro, H., Yazaki, S., Horiuchi, Y., Arai, M., Niizato, K., Iritani, S., Itokawa, M., Inada, T., Iwata, N., et al. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp166 · Cited by 112 · see citing works
Self-citationAntidepressant action of HDAC inhibition in the prefrontal cortex
Covington, H. E., Maze, I., Vialou, V., & Nestler, E. J. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.04.030 · Cited by 97 · see citing works
Cahill, E., Pascoli, V., Trifilieff, P., Savoldi, D., Kappès, V., Lüscher, C., Caboche, J., & Vanhoutte, P. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.73 · Cited by 92 · see citing works
Self-citationACF chromatin-remodeling complex mediates stress-induced depressive-like behavior
Sun, H., Damez-Werno, D. M., Scobie, K. N., Shao, N.-Y., Dias, C., Rabkin, J., Koo, J. W., Korb, E., Bagot, R. C., Ahn, F. H., et al. (2015) · Nature Medicine · doi:10.1038/nm.3939 · Cited by 91 · see citing works
Johnson, T. A., Elbi, C., Parekh, B. S., Hager, G. L., & John, S. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-02-0123 · Cited by 90 · see citing works
Molecular basis of dendritic atrophy and activity in stress susceptibility
Francis, T. C., Chandra, R., Gaynor, A., Konkalmatt, P., Metzbower, S. R., Evans, B., Engeln, M., Blanpied, T. A., & Lobo, M. K. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.178 · Cited by 89 · see citing works
Anti-inflammatory functions of the glucocorticoid receptor require DNA binding
Escoter-Torres, L., Greulich, F., Quagliarini, F., Wierer, M., & Uhlenhaut, N. H. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa565 · Cited by 83 · see citing works
Expression of Cre recombinase in dopaminoceptive neurons
Lemberger, T., Parlato, R., Dassesse, D., Westphal, M., Casanova, E., Turiault, M., Tronche, F., Schiffmann, S. N., & Schütz, G. (2007) · BMC Neuroscience · doi:10.1186/1471-2202-8-4 · Cited by 76 · see citing works
Self-citationBramswig, N. C., Lüdecke, H., Alanay, Y., Albrecht, B., Barthelmie, A., Boduroğlu, K., Braunholz, D., Caliebe, A., Chrzańowska, K., Czeschik, J. C., et al. (2015) · Human Genetics · doi:10.1007/s00439-015-1535-8 · Cited by 65 · see citing works
Trotter, K. W., Fan, H.-Y., Ivey, M. L., Kingston, R. E., & Archer, T. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01301-07 · Cited by 65 · see citing works
Pascoli, V., Cahill, E., Bellivier, F., Caboche, J., & Vanhoutte, P. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.04.005 · Cited by 63 · see citing works
Self-citationSalery, M., Santos, M. D., Saint‐Jour, E., Moumné, L., Pagès, C., Kappès, V., Parnaudeau, S., Caboche, J., & Vanhoutte, P. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.05.025 · Cited by 62 · see citing works
Self-citationWhite, A. O., Kramár, E. A., López, A. J., Kwapis, J. L., Doan, J., Saldana, D., Davatolhagh, M. F., Alaghband, Y., Blurton-Jones, M. M., Matheos, D. P., et al. (2016) · Nature Communications · doi:10.1038/ncomms11725 · Cited by 56 · see citing works
Imbalzano, K. M., Cohet, N., Wu, Q., Underwood, J. M., Imbalzano, A. N., & Nickerson, J. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055628 · Cited by 54 · see citing works
Tuoc, T., Dere, E., Radyushkin, K., Pham, L., Nguyen, H., Tonchev, A. B., Sun, G., Ronnenberg, A., Shi, Y., Staiger, J. F., et al. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9948-5 · Cited by 52 · see citing works
Barik, J., Parnaudeau, S., Lampin-Saint-Amaux, A., Guiard, B. P., Dzib, J. F. G., Bocquet, O., Bailly, A., Benecke, A., & Tronche, F. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.03.037 · Cited by 49 · see citing works
Self-citationAntidepressive effects of targeting ELK-1 signal transduction
Apazoglou, K., Farley, S., Gorgievski, V., Belzeaux-R, R., López, J. P., Grenier, J., Ibrahim, E. C., Khoury, M. E., Tse, Y. C., Mongrédien, R., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0011-0 · Cited by 45 · see citing works
Self-citationLiu, L., Xuan, C., Shen, P., He, T., Chang, Y., Shi, L., Tao, S., Yu, Z., Brown, R. E., & Wang, J. (2018) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2018.00035 · Cited by 45 · see citing works
Nixon, K. C. J., Rousseau, J., Stone, M. H., Sarikahya, M. H., Ehresmann, S., Mizuno, S., Matsumoto, N., Miyake, N., Baralle, D., McKee, S. A., et al. (2019) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2019.02.001 · Cited by 45 · see citing works
BRG1 in the Nucleus Accumbens Regulates Cocaine-Seeking Behavior
Wang, Z.-J., Martin, J. A., Mueller, L. E., Caccamise, A. J., Werner, C. T., Neve, R. L., Gancarz, A. M., Li, J., & Dietz, D. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.04.020 · Cited by 41 · see citing works
Sun, H., Martin, J. A., Werner, C. T., Wang, Z.-J., Damez-Werno, D. M., Scobie, K. N., Shao, N., Dias, C., Rabkin, J., Koo, J. W., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3254-15.2016 · Cited by 40 · see citing works
Engel, K. B., & Yamamoto, K. R. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05351-11 · Cited by 37 · see citing works
Monitoring Histone Methylation (H3K9me3) Changes in Live Cells
Sánchez, O. F., Mendonca, A., Min, A., Liu, J., & Yuan, C. (2019) · ACS Omega · doi:10.1021/acsomega.9b01413 · Cited by 37 · see citing works
Parnaudeau, S., Dongelmans, M. L., Turiault, M., Ambroggi, F., Delbès, A.-S., Cansell, C., Luquet, S. H., Piazza, P., Tronche, F., & Barik, J. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00035 · Cited by 34 · see citing works
Self-citationYoo, M., Choi, K., Kim, J., Kim, M., Shim, J., Choi, J., Cho, H.-Y., Oh, J.-P., Kim, H.-S., Kaang, B., et al. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3220-16.2017 · Cited by 24 · see citing works
Chubak, M. C., Nixon, K. C. J., Stone, M. H., Raun, N., Rice, S. L., Sarikahya, M. H., Jones, S. G., Lyons, T. A., Jakub, T. E., Mainland, R. L., et al. (2019) · Disease Models & Mechanisms · doi:10.1242/dmm.037325 · Cited by 19 · see citing works
Wang, X., Geng, X., Li, M., Xie, J., Chen, D., Han, H., Meng, X., Yao, X., Zhang, H., Gao, Y., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01034 · Cited by 13 · see citing works
Dopamine and glutamate receptors control social stress-induced striatal ERK1/2 activation
Contesse, T., Broussot, L., Fofo, H., Vanhoutte, P., Fernández, S. P., & Barik, J. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108534 · Cited by 9 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 1
- [74]Paxinos, G. & Watson, C. The mouse brain in stereotaxic coordinates. 5 (Elsevier, 2004).
Cited by
Sorted by citations
Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246 · see citing works
“379 Other studies reported altered levels of selective ATP-dependent chromatin remodeling factors in mice with high anxiety-related behavior, including SNF2H in the amygdala and CHD3 and CHD5 in the ventral hippocampus.”
Background
- Authors
- Zayed, A., Baranowski, C., Compagnion, A.-C., Vernochet, C., Karaki, S., Cuttoli, R. D.-D., Saint-Jour, E., Bhattacharya, S., Marti, F., Vanhoutte, P., Yaniv, M., Faure, P., Barik, J., Amar, L., Tronche, F., & Parnaudeau, S.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Tronche, François
- ORCID
- Venue
- Nature Communications
- Published
- 2022-04-04
- Volume
- 13
- Issue
- 1
- Pages
- 1807-1807
- ISSN
- 2041-1723 (ISSN-L)
- PMC
- PMC8980038
- OpenAlex
- W4225846741
- Cited by
- 17
- References
- 85
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 3 · 2023: 5 · 2022: 1
- FWCI
- 1.06
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Nature Communications (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- HAL (submittedVersion, cc-by)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Agence Nationale de la Recherche (ANR3053NEUR3143830)
- Institut National Du Cancer (TABAC)
- Fondation pour la Recherche Médicale (DEQ20140329552)
- Labex BioPsy Grant Social status, social behavior and psychiatric disorders Sorbonne Université, Emergence Program Stress, Transcription and Behavior
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Chromatin Remodeling and Cancer
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Keywords
- SWI/SNF chromatin remodeling, SMARCA4, BRM, social defeat, stress resilience, striatal medium spiny neurons, heterochromatin, chromatin accessibility, immediate early genes, midbrain dopaminergic neurons, epigenetic adaptation
- MeSH terms
- Adenosine Triphosphatases, Animals, Chromatin, Reward, Chromatin Assembly and Disassembly, Cell Line, Tumor, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
