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Somatic genetic rescue in Mendelian haematopoietic diseases
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“Subsequent studies have shown that they remove the negative fitness constraint induced by the sustained activation of p53 (Fig. 5). This allows enough hematopoietic cells to survive to avoid any lethal phenotypes [159].”
From The TP53 tumor suppressor gene: From molecular biology to clinical investigations (2025) · cites this paper as [159]
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Cited by
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Metadata
- Authors
- Revy, P., Kannengiesser, C., & Fischer, A.
- ORCID
- Revy, Patrick
- Venue
- Nature Reviews Genetics
- Published
- 2019-06-11
- Volume
- 20
- Issue
- 10
- Pages
- 582-598
- ISSN
- 1471-0056
- 1471-0064
- Cited by
- 134
- References
- 15
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
- www.springer.com/tdm (vor)
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