The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease

Neurotoxic reactive astrocytes are induced by activated microglia

Liddelow, S. A., Guttenplan, K. A., Clarke, L. E., Bennett, F. C., Bohlen, C. J., Schirmer, L., Bennett, M. L., Münch, A. E., Chung, W.-S., Peterson, T. C., et al. (2017) · Nature · doi:10.1038/nature21029 · Cited by 7,971

Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease

Sampson, T. R., Debelius, J. W., Thron, T., Janssen, S., Shastri, G. G., Ilhan, Z. E., Challis, C., Schretter, C. E., Rocha, S., Gradinaru, V., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.018 · Cited by 3,622

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006) · Immunity · doi:10.1016/j.immuni.2006.01.001 · Cited by 3,605

Host microbiota constantly control maturation and function of microglia in the CNS

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Microglia Function in the Central Nervous System During Health and Neurodegeneration

Colonna, M., & Butovsky, O. (2017) · Annual Review of Immunology · doi:10.1146/annurev-immunol-051116-052358 · Cited by 2,894

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

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Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22

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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Opitz, C. A., Litzenburger, U. M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., et al. (2011) · Nature · doi:10.1038/nature10491 · Cited by 1,898

IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells

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Activation of the Aryl Hydrocarbon Receptor by Structurally Diverse Exogenous and Endogenous Chemicals

Denison, M. S., & Nagy, S. R. (2003) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.43.100901.135828 · Cited by 1,895

A molecular cell atlas of endocrine signaling in human neural organoids

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Microbiome‐Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease

Mahdiabadi, M., Moghaddam, A., & Erfanian, N. (2026) · MicrobiologyOpen · doi:10.1002/mbo3.70386 · Cited by 2

Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells

Huang, J., Wang, Y., & Zhou, Y. (2023) · World Journal of Stem Cells · doi:10.4252/wjsc.v15.i8.807 · Cited by 2

Aryl hydrocarbon receptor gene expression in ankylosing spondylitis and its correlation with interleukin-17, RAR-related orphan receptor gamma t expression, and disease activity indices

Ahmadi, M., Soleimanifar, N., Rostamian, A., Sadr, M., Mojtahedi, H., Mazari, A., Nicknam, M. H., & Assadiasl, S. (2024) · Archives of Rheumatology · doi:10.46497/archrheumatol.2023.10203 · Cited by 2

Dioxin-Induced PAI-1 Expression: A Novel Pathway to Pancreatic β-Cell Failure in Type 2 Diabetes

Im, S., Kang, S., Son, W. J., Son, M., Oh, S. J., Yoon, H. J., & Pak, Y. K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252211974 · Cited by 2

How exercise shapes the anti-inflammatory environment in multiple sclerosis – a conceptual framework focusing on tryptophan-derived molecules in T cell differentiation

Chirino, T. Y. W., Joisten, N., Zimmer, P., & Proschinger, S. (2024) · Translational Exercise Biomedicine · doi:10.1515/teb-2024-0037 · Cited by 2

Exposomal determinants of non-genetic plasticity in tumor initiation

Carra, D., Maas, S. C. E., Seoane, J. A., & Alonso‐Curbelo, D. (2025) · Trends in cancer · doi:10.1016/j.trecan.2025.01.010 · Cited by 2

The differential role of aryl hydrocarbon receptor in skin cancers induced by environmental carcinogens, including ultraviolet irradiation, arsenic exposure, and HPV infection

Tseng, H., Lai, P., & Lee, C. (2025) · Dermatologica Sinica · doi:10.4103/ds.ds-d-24-00092 · Cited by 2

Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity

Anderson, S. J., Scott, E. N., Raack, E. J., Chang, W., Córdova‐Delgado, M., Trueman, J. N., Loucks, C. M., Rassekh, S. R., Ross, C. J., & Carleton, B. (2025) · Pediatric Blood & Cancer · doi:10.1002/pbc.31668 · Cited by 2

Effect of omega-3 and omega-6 fatty acids on tumor suppressor pathways in mice tongue oral epithelial dysplasia

Don, J. A., Ferrero, V., Mazo, T., Bernárdez, S., Barotto, N. N., Brunotto, M. N., & Pasqualini, M. E. (2025) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2025.106283 · Cited by 2

Enhancement of 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity by lipopolysaccharide in developing zebrafish lacking canonical pattern recognition pathways

Kitamura, H., Tanaka, K., Wang, H., Nakamura, T., Kobayashi, M., & Teraoka, H. (2025) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2025.110261 · Cited by 2

Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells

Tabęcka-Łonczyńska, A., Skóra, B., Szlachcikowska, D., Jastrząb, R., Marć, M. A., Mytych, J., Koszła, O., Sołek, P., & Szychowski, K. A. (2025) · Pharmacological Reports · doi:10.1007/s43440-025-00767-w · Cited by 2

Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes

Cros, A., Rigamonti, A., de Juan, A., Coillard, A., Rieux-Laucat, M., Tabtim-On, D., Papillon, E., Goudot, C., Cepika, A., Banchereau, R., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci189937 · Cited by 2

Tryptophan metabolites and the microbiome-gut-brain axis in major gut disorders

Gașpar, B. S., Profir, M., & Creţoiu, S. M. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1004564 · Cited by 2

Next-generation microbial drugs developed from microbiome's natural products

Bhattarai, K., Bhattarai, K., & Baral, B. (2021) · Advances in genetics · doi:10.1016/bs.adgen.2021.08.007 · Cited by 2

Pelargonidin and its glycosides as dietary chemopreventives attenuating inflammatory bowel disease symptoms through the aryl hydrocarbon receptor

Dvořák, Z. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02316-y · Cited by 2

Genomics-based deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid AHR signaling dynamicsPreprint

Gupta, A. A., Sasse, S. K., Gruca, M. A., Sanford, L., Dowell, R. D., & Gerber, A. N. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.02.23.432311 · Cited by 2

Aryl Hydrocarbon Receptor

Safe, S. H. (2021) · Springer eBooks · doi:10.1007/978-3-030-57401-7_10046 · Cited by 3

Amino acids: Specific functions

Wu, G. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821848-8.00049-4 · Cited by 2

Metadichol® a nano lipid emulsion that expresses all 48 nuclear receptors in stem and somatic cellsPreprint

Raghavan, P. R. (2022) · Research Square · doi:10.21203/rs.3.rs-1797646/v1 · Cited by 2

Molecular Evolution of Aryl Hydrocarbon Receptor Signaling Pathway GenesPreprint

Bhalla, D., & van Noort, V. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.13.499904 · Cited by 2

Tryptophan catabolism by gut microbiota : A bridge connecting food science and human nutrition

Huang, Z. (2023) · doi:10.18174/583090 · Cited by 2

Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cellsPreprint

Sanmarco, L., Rone, J. M., Polonio, C., Giovannoni, F., Lahore, G. F., Ferrara, K., Gutiérrez-Vázquez, C., Li, N., Sokolovska, A., Plasencia, A., et al. (2023) · bioRxiv · doi:10.1101/2023.03.17.532101

Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in ESRDPreprint

Kim, H. Y., Kim, D. H., Lee, S. J., Kang, Y. J., Kim, G., Koh, H. B., Ko, Y. E., Shin, H. M., Lee, H., Yoo, T., et al. (2023) · eLife · doi:10.7554/elife.87316.1 · Cited by 2

Dynamic oncogene activity metabolically reprograms the tryptophan– kynurenine–AHR axis driving immune evasion and tumor progression in Ewing sarcomaPreprint

Carreño-Gonzalez, M. J., Hanssen, K. M., Sadik, A., Henneberg, A., Knott, M. M. L., Ehlers, A. C., Ceranski, A. K., Kolodynska, Z., Zimmermann, M., Imle, R., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.16.654502 · Cited by 2

A step towards animal models with self-sustained fungal bioluminescencePreprint

Gleneadie, H. J., Veland, N., Warren, E. C., Sardini, A., Barroso, C., Fadeeva, A. A., Webster, Z., Dormann, D., Gao, F., Martínez-Pérez, E., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.04.668132 · Cited by 2

A molecular cell atlas of endocrine signalling in human neural organoidsPreprint

Matassa, G., Rigoli, M. T., Castaldi, D., Valenti, A., Lessi, M., Caporale, N., Stucchi, S., Muda, B., Nagni, R., Mainardi, L. T., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.14.669814 · Cited by 2

Role of astrocytes in neuroinflammation (review)

Mordovina, A. I., Rudenko, Е. Е., & Демура, Т. А. (2023) · Saratov Journal of Medical Scientific Research · doi:10.15275/ssmj1901089 · Cited by 1

2D materials and the microbiome: More than a gut feeling

Peng, G., & Fadeel, B. (2023) · Current Opinion in Toxicology · doi:10.1016/j.cotox.2023.100427 · Cited by 1

Intestinal Lactobacillus johnsonii protects against neuroangiostrongyliasis in BALB/c mice through modulation of immune response

Lam, L. Y., Liang, T.-R., Wu, W.-J., & Lam, H. Y. P. (2025) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0012977 · Cited by 1

Single-cell analysis of pig lung leukocytes and their response to influenza infection and oseltamivir therapy

Madrid, D. M. D. C., Gu, W., Karim, S. J. I., Lowke, M. T., Kelleher, A. M., Warren, W. C., & Driver, J. P. (2025) · The Journal of Immunology · doi:10.1093/jimmun/vkaf032 · Cited by 3

KYNA Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via FTO ‐Dependent m6A Demethylation of LATS1

Zheng, W., Wang, X., Chen, H., He, K., Yan, X., Zhang, Y., Yang, Y., Zhang, P., Zhu, W., Zhu, S., et al. (2025) · Cell Proliferation · doi:10.1111/cpr.70048 · Cited by 1

Gut Microbial Metabolites as Diagnostic Biomarkers

Taleuzzaman, M., Anupam, Verma, M., Chaudhary, K., & Choudhary, R. (2025) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815324549125010012 · Cited by 2

Design and conduct of a full diet-controlled, parallel, 2-week residential trial for diabetes prevention without weight loss in Asian Chinese and European Caucasian adults with prediabetes: the New Zealand SYNERGY study

Sequeira, I. R., Fraser, K., Leiu, K. H., Penhaligan, J., Joblin-Mills, A., Plank, L. D., Murphy, R., Taylor, M. W., Gasser, O., Conroy, D. M., et al. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1590579 · Cited by 1

Ligand- and tissue-specific differences in the activation of the aryl hydrocarbon receptor by flavonoids: A focus on baicalein and scutellarein

Xu, T., Liu, Y., Han, F., Xie, H. Q., Wang, R., Wang, R., & Xu, S. L. (2025) · Food and Chemical Toxicology · doi:10.1016/j.fct.2025.115713 · Cited by 1

Hypoxia-Inducible Factor Signaling Compensates for Aryl Hydrocarbon Receptor in Maintaining Gut Barrier Integrity

Gwak, M.-G., Kim, M.-S., Park, S., Oh, S., Kim, Y., Kim, J., & Chang, S. (2025) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaf155 · Cited by 2

The role of aryl hydrocarbon receptor signalling in COVID-19 pathology and its therapeutic potential

Mbambara, S., Modipane, N. R., Serite, T., Sathekge, M. M., & Kgatle, M. (2025) · Frontiers in Molecular Medicine · doi:10.3389/fmmed.2025.1599785 · Cited by 1

Infectious Bronchitis Virus Activates the Aryl Hydrocarbon Receptor During In Vitro Infection

Zhang, M., Cai, Z., An, H., He, R., Zhang, S., & Fang, S. (2025) · Veterinary Sciences · doi:10.3390/vetsci12100932 · Cited by 1

Potential mechanisms of natural metabolites and botanical drugs foumulae for the treatment of non-alcoholic fatty liver disease: targeting the gut microbiota to modulate the immune system

Zhang, Y., Liu, L., Song, R., Qu, Z., Wang, T., Liang, L., Wang, S., Zhang, S., Li, H., & Wang, H. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1653372 · Cited by 1

Particulate matter extracted from human anthracotic tissues induces inflammatory markers in co-culture of lung cells and macrophages

Frias, D. P., Vieira, G. L., Smelan, J., de Lacerda, J. P. A., da Silva, P. S. C., Sussa, F. V., Carvalho-Oliveira, R., Saldiva, P. H. N., Mauad, T., & Macchione, M. (2025) · Toxicology · doi:10.1016/j.tox.2025.154299 · Cited by 1

Indole-3-carboxamide alleviates LPS-induced endometritis through suppressing ferroptosis and inflammation via regulating Aryl hydrocarbon receptor

Chen, F., Cheng, R., Chen, X., & Guo, Z. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1649801 · Cited by 1

Microbiome and Metabolic Immune Mechanisms in Sepsis-Associated Encephalopathy

Nan, Z. (2025) · Journal of Intensive Care Medicine · doi:10.1177/08850666251385540 · Cited by 2

Altered milk tryptophan and tryptophan metabolites in women living with HIV

Tobin, N. H., Li, F., Zhu, W., Ferbas, K. G., Sleasman, J. W., Raftery, D., Kuhn, L., & Aldrovandi, G. M. (2025) · Nature Communications · doi:10.1038/s41467-025-64566-w · Cited by 1

FTO-ACKR3 Axis Regulates Polycyclic Aromatic Hydrocarbons-Induced Asthma Attacks via AhR-Mediated m 6 A RNA Methylation

Liu, S., Chu, J., Xin, J., Yin, X., He, Z., Qin, S., & Song, X. (2025) · Environment & Health · doi:10.1021/envhealth.5c00261 · Cited by 1

Drug-Induced Glucose Metabolism Disorders: Role of Aryl Hydrocarbon Receptor

Grishanova, A. Y., & Perepechaeva, M. L. (2025) · Journal of Xenobiotics · doi:10.3390/jox15060206 · Cited by 1

The role of bHLH-PAS transcription factors in endoplasmic reticulum stress

Krauze, I., Krzystek‐Korpacka, M., Maciejewska, K., & Greb‐Markiewicz, B. (2025) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2025.1730502 · Cited by 1

MiR-124-3p inhibits stomach adenocarcinoma progression by targeting AHR to induce autophagy

Wan, Q., Wang, S., Dong, W., Liu, X., Li, X., Liu, C., & Xu, S. (2025) · Cell Division · doi:10.1186/s13008-025-00175-9 · Cited by 1

AHR: The Overlooked Mediator in Skincare─Bridging Environmental Sensing and Skin Physiology

Hu, X., Zhu, R., Zhen, Y., Li, Q., Liu, Y., Xu, T., Yang, G., Chen, Y., Xie, H. Q., Xu, S. L., et al. (2026) · Environment & Health · doi:10.1021/envhealth.5c00424 · Cited by 1

Piecing together the puzzles: Aryl hydrocarbon receptor-mediated genetic and epigenetic signatures in dioxin-induced carcinogenicity- A systematic review and meta-analysis

Hefnawy Ahmad, A., Mohamed, S., Alkhaldi, M. Y., Asiri, H., Ali, A. M., Shaher, F. A., Al-Shahrani, M. S., Al-qarni, M. A., & El-Hawary, H. M. (2026) · Toxicology Letters · doi:10.1016/j.toxlet.2026.111827 · Cited by 1

Proinsulin-Loaded Nanoparticles Suppress Insulitis and Induce Temporary Diabetes Remission

Agapoff, M., Dubreil, C., Waeckel-Énée, E., Geinguenaud, F., Manceau, V., Diana, J., Bertocci, B., Motte, L., & van Endert, P. (2026) · Cells · doi:10.3390/cells15020174 · Cited by 1

A shared metabolic-immune axis links local and systemic inflammation in chronic rhinosinusitis with comorbid asthma

Peng, X. X., Li, Z., Liang, Y., & Zhang, G. (2026) · Frontiers in Allergy · doi:10.3389/falgy.2025.1700350 · Cited by 1

Gut Microbiota as Neuroimmune Modulators in Myasthenia Gravis: Mechanistic Insights from the Gut-Brain Axis to Therapeutic Innovations

Lv, J., Liu, R., Sun, Z., Zhang, J., Zhang, Y., Zhao, X., Liu, J., Zhou, X., Zhang, M., Liu, Q., et al. (2026) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x26500023 · Cited by 1

eIF6 deficiency alleviates colorectal cancer by modulating the gut microbiota and related metabolites

Yang, S., Song, J., Zhenzhen, W. A. N. G., Peng, G., Tong, L., Li, X., Yang, K., Chen, Y., Zhang, H., Zhang, Q., et al. (2026) · Cell Death and Differentiation · doi:10.1038/s41418-026-01674-0 · Cited by 1

Emerging roles of IL4I1 in regulating tumor immunity and ferroptosis

Hu, Y., Jiang, Y., Du, Y., Zheng, Y., & Xia, X. (2026) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2026.189553 · Cited by 1

Exploration of Agonist and Antagonist Binding Sites within the Cytosolic AHR Complex Using Molecular Modeling

Karabogdan, I., Yanqui-Rivera, F., Sayeeram, D., Sadik, A., Miller, A. K., Trump, S., Röhrig, U. F., & Opitz, C. A. (2026) · ACS Omega · doi:10.1021/acsomega.5c10598 · Cited by 1

Potential Activity of 6-Pentyl-α-pyrone as an Antiviral for Bovine Coronavirus

Sorbo, L. D., Giugliano, R., Acconcia, C., Salvatore, M. M., Staropoli, A., Vasinioti, V. I., Lucente, M. S., Capozza, P., Vinale, F., Pratelli, A., et al. (2026) · Pathogens · doi:10.3390/pathogens15030332 · Cited by 1

Interferon-β and FTY720 ameliorate progressive CNS inflammation via SOCS1-associated astrocyte signaling

Tsaktanis, T., Beyer, T., Nirschl, L., Rotaru, A.-I., Engleitner, T., Öllinger, R., Zuber, F., Peter, A., Zißler, J., Tschurl, V., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-45303-9 · Cited by 1

Leptomeningeal metastatic cancer cells induce a permissive choroid plexus vasculature through extracellular-vesicle-derived 5-HIAA signaling

Huang, Y., Hou, Y., Yang, J., Yang, W., Liu, H., Peng, H., Li, X., Zhao, J., Zhang, Y., Zeng, R., et al. (2026) · Nature Cancer · doi:10.1038/s43018-026-01145-y · Cited by 2

Fecal tryptophan metabolism predicts the development of infant eczema: a prospective longitudinal study

Wieser, N. V., Admiraal, I., Weiss, R., Ghiboub, M., Davids, M., Lefèvre, A., Emond, P., Powell, E. A., Sim, K., Kroll, J. S., et al. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2655171 · Cited by 1

Microbiota and Guillain-Barré syndrome: role of microbial metabolites, biomarkers, and emerging therapeutic strategies

Zurdo-López, M. M., del Rio, M. S., Rudilla, M. C., Ibarra, A., & Doncel‐Pérez, E. (2026) · Frontiers in Neurology · doi:10.3389/fneur.2026.1815899 · Cited by 1

A Review of Aryl Hydrocarbon Receptor–Mediated Immune Regulation in Cutaneous Squamous Cell Carcinoma Progression

Han, H., Dong, Q., Zhang, Z., Li, S., Zhang, H., Wang, X., Bai, J., Shi, L., Fu, X., Zheng, K., et al. (2026) · ImmunoTargets and Therapy · doi:10.2147/itt.s601152 · Cited by 1

Aryl hydrocarbon receptor pharmacology—mechanisms, ligands, and therapeutic potential

Bobrovs, R., Olafsen, N. E., Åhrling, S. S., & Matthews, J. B. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100146 · Cited by 2

Gut–bone axis in rheumatoid arthritis: microbiota-driven barrier dysfunction, immune crosstalk, and therapeutic strategies

Hu, Z., Yan, J., Wang, X., & Liu, Z. (2026) · Antonie van Leeuwenhoek · doi:10.1007/s10482-026-02353-3 · Cited by 1

Hospital-treated infection associated with Alzheimer’s disease pathology: underlying mechanisms

Barichello, T., Scaini, G., Tayyab, M., Dal-Pizzol, H. R., Petronilho, F. C., & Dal‐Pizzol, F. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03690-5 · Cited by 1

The regulatory mechanisms of Indole-3-carboxaldehyde in immune cells and its role in autoimmune diseases

Xin, Y., Cen, Q., He, J., Lu, W., Yu, Y., Jing, F., Zhao, Y., Jin, J., Cui, Y., Feng, J., et al. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108303 · Cited by 1

The hepato-exposome axis: How endocrine disruptors hijack liver receptors to drive MASLD

Martín-Grau, M., Kamstra, J. H., Hyötyläinen, T., Orešič, M., Song, Y., Veličković, N. A., Djordjevic, A. D., Milutinović, D. V., Jackson, R. F., van Vorstenbosch, R., et al. (2026) · Journal of Hepatology · doi:10.1016/j.jhep.2026.06.021 · Cited by 1

Intestinal neutral ceramidase exacerbates MASH pathogenesis

Wang, T., Chen, L., Lei, C., Song, X., Tuohongerbieke, A., Feng, J., Gasparetto, R. L., Zhang, X., McClain, C. J., Tan, Y., et al. (2026) · eGastroenterology · doi:10.1136/egastro-2026-100417 · Cited by 1

Deficiency of the aryl hydrocarbon receptor in intestinal epithelial cells, but not hepatocytes, ameliorates atherosclerosis development by sex-dependently targeting the lipid metabolism

Huchzermeier, R., Rakateli, L., Corcini-Berndt, M., Maas, S. L., Abschlag, K., Pöttgens, C. C. H., Moellmann, J., Pirker, T., Kremer, S., Steitz, J., et al. (2026) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2026.121857 · Cited by 1

The exposome-autoimmunity axis: environmental xenobiotics, gut dysbiosis, and potential pathways to immunosenescence

Daşdemir, F. O., Sari, M. F., Aktaş, B., & Kocazeybek, B. S. (2026) · Food and Chemical Toxicology · doi:10.1016/j.fct.2026.116331 · Cited by 1

Nobiletin restores colonic epithelial homeostasis in DSS-induced colitis with involvement of the aryl hydrocarbon receptor

Li, X., Wu, H., Yang, Y., Tan, B., Zhang, J., Ma, J., Zhang, J., An, K., & Ge, F. (2026) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2026.179219 · Cited by 1

Gut microbiota‐derived tryptophan metabolite attenuates calcium oxalate nephropathy by suppressing renal tubular cell apoptosis through the AhR – SOCS3 – STAT1 axis

Li, Y., Chen, J., 林, 乐., Jian, Z., Liu, L., Wang, M., Wei, J., Chen, X., Yang, M., Li, T., et al. (2026) · The Journal of Pathology · doi:10.1002/path.70135 · Cited by 1

Sex-dependent compensatory mechanisms preserve blood pressure homeostasis in prostacyclin receptor–deficient mice

Tang, S. Y., Meng, H., Anderson, S. T., Sarantopoulou, D., Ghosh, S., Lahens, N. F., Theken, K. N., Ricciotti, E., Hennessy, E. J., Tu, V., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci136310 · Cited by 1

Neuroinflamación mediada por los astrocitos en el envejecimiento y la neurodegeneración a través del factor nuclear ϰβ y el receptor de hidrocarburos de arilo

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