Quintana, Francisco J.

Reactive astrocyte nomenclature, definitions, and future directions

Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 2,513

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

Quintana, F. J., Basso, A. S., Iglesias, A. H., Korn, T., Farez, M. F., Bettelli, E., Caccamo, M., Oukka, M., & Weiner, H. L. (2008) · Nature

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 1,865

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

Rothhammer, V., Mascanfroni, I. D., Bunse, L., Takenaka, M. C., Kenison, J. E., Mayo, L., Chao, C.-C., Patel, B., Yan, R., Blain, M., et al. (2016) · Nature Medicine

Tryptophan and brain disordersinterferon and immune responses

Cited by 1,559

Alterations of the human gut microbiome in multiple sclerosis

Jangi, S., Gandhi, R., Cox, L. M., Li, N., von Glehn, F., Yan, R., Patel, B., Mazzola, M. A., Liu, S., Glanz, B. L., et al. (2016) · Nature Communications

Gut microbiota and healthMultiple Sclerosis Research Studies

Cited by 1,307

The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease

Rothhammer, V., & Quintana, F. J. (2019) · Nature Reviews Immunology

Toxic Organic Pollutants ImpactNuclear Receptors and Signaling

Cited by 1,197

Induction and molecular signature of pathogenic TH17 cells

Lee, Y., Awasthi, A., Yosef, N., Quintana, F. J., Xiao, S., Peters, A., Wu, C., Kleinewietfeld, M., Kunder, S., Hafler, D. A., et al. (2012) · Nature Immunology

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 1,174

Microglial control of astrocytes in response to microbial metabolites

Rothhammer, V., Borucki, D. M., Tjon, E. C., Takenaka, M. C., Chao, C.-C., Ardura-Fabregat, A., de Lima, K. A., Gutiérrez-Vázquez, C., Hewson, P., Staszewski, O., et al. (2018) · Nature

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 1,051

Astrocyte Crosstalk in CNS Inflammation

Linnerbauer, M., Wheeler, M. A., & Quintana, F. J. (2020) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 989

Regulation of the immune response by the aryl hydrocarbon receptor

Gutiérrez-Vázquez, C., & Quintana, F. J. (2018) · Immunity

Toxic Organic Pollutants ImpactImmune Response and Inflammation

Cited by 985

Negative feedback control of neuronal activity by microglia

Badimon, A., Strasburger, H. J., Ayata, P., Chen, X., Nair, A., Ikegami, A., Hwang, P., Chan, A. T., Graves, S. M., Uweru, J. O., et al. (2020) · Nature

Neuroinflammation and Neurodegeneration MechanismsAdenosine and Purinergic Signaling

Cited by 979

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

Apetoh, L., Quintana, F. J., Pot, C., Joller, N., Xiao, S., Kumar, D., Burns, E. J., Sherr, D. H., Weiner, H. L., & Kuchroo, V. K. (2010) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 725

Function and therapeutic value of astrocytes in neurological diseases

Lee, H.-G., Wheeler, M. A., & Quintana, F. J. (2022) · Nature Reviews Drug Discovery

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 662

Microglia and Central Nervous System–Associated Macrophages—From Origin to Disease Modulation

Prinz, M., Masuda, T., Wheeler, M. A., & Quintana, F. J. (2021) · Annual Review of Immunology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 584

Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

Takenaka, M. C., Gabriely, G., Rothhammer, V., Mascanfroni, I. D., Wheeler, M. A., Chao, C.-C., Gutiérrez-Vázquez, C., Kenison, J., Tjon, E. C., Barroso, A., et al. (2019) · Nature Neuroscience

Immune cells in cancerGlioma Diagnosis and Treatment

Cited by 517

MAFG-driven astrocytes promote CNS inflammation

Wheeler, M. A., Clark, I. C., Tjon, E. C., Li, Z., Zandee, S. E. J., Couturier, C. P., Watson, B. R., Scalisi, G., Alkwai, S., Rothhammer, V., et al. (2020) · Nature

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 501

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

Sanmarco, L. M., Wheeler, M. A., Gutiérrez-Vázquez, C., Polonio, C. M., Linnerbauer, M., Pinho-Ribeiro, F. A., Li, Z., Giovannoni, F., Batterman, K. V., Scalisi, G., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration Mechanismsinterferon and immune responses

Cited by 331

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

Farez, M. F., Mascanfroni, I. D., Méndez-Huergo, S. P., Yeste, A., Murugaiyan, G., Garo, L. P., Balbuena Aguirre, M. E., Patel, B., Ysrraelit, M. C., Zhu, C., et al. (2015) · Cell

Multiple Sclerosis Research StudiesCircadian rhythm and melatonin

Cited by 318

Barcoded viral tracing of single-cell interactions in central nervous system inflammation

Clark, I. C., Gutiérrez-Vázquez, C., Wheeler, M. A., Li, Z., Rothhammer, V., Linnerbauer, M., Sanmarco, L. M., Guo, L., Blain, M., Zandee, S. E. J., et al. (2021) · Science

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 285

Heat Shock Proteins as Endogenous Adjuvants in Sterile and Septic Inflammation

Quintana, F. J., & Cohen, I. R. (2005) · The Journal of Immunology

Heat shock proteins researchImmune Response and Inflammation

Cited by 219

Control of autoimmune CNS inflammation by astrocytes

Rothhammer, V., & Quintana, F. J. (2015) · Seminars in Immunopathology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 214

Repositioning TH cell polarization from single cytokines to complex help

Tuzlak, S., Dejean, A. S., Iannacone, M., Quintana, F. J., Waisman, A., Ginhoux, F., Korn, T., & Becher, B. (2021) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 171

The aryl hydrocarbon receptor and the gut–brain axis

Barroso, A., Mahler, J. V., Fonseca-Castro, P. H., & Quintana, F. J. (2021) · Cellular & Molecular Immunology

Toxic Organic Pollutants ImpactGut microbiota and health

Cited by 152

Role of Sphingolipid Metabolism in Neurodegeneration

Alaamery, M., Albesher, N., Aljawini, N., Alsuwailm, M., Massadeh, S., Wheeler, M. A., Chao, C., & Quintana, F. J. (2021) · Journal of Neurochemistry

Sphingolipid Metabolism and SignalingLysosomal Storage Disorders Research

Cited by 129

Environmental control of autoimmune inflammation in the central nervous system

Rothhammer, V., & Quintana, F. J. (2016) · Current Opinion in Immunology

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 52