Sex differences in anxiety and depression: circuits and mechanisms

Diagnostic and Statistical Manual of Mental Disorders

American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works

Twelve‐month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States

Kessler, R. C., Petukhova, M., Sampson, N. A., Zaslavsky, A. M., & Wittchen, H. (2012) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.1359 · Cited by 2,947 · see citing works

Explaining the gender difference in depressive symptoms.

Nolen-Hoeksema, S., Larson, J., & Grayson, C. (1999) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.77.5.1061 · Cited by 1,543 · see citing works

Sex differences in anxiety and depression clinical perspectives

Altemus, M., Sarvaiya, N., & Neill Epperson, C. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.05.004 · Cited by 1,413 · see citing works

Learned helplessness at fifty: Insights from neuroscience.

Maier, S. F., & Seligman, M. E. P. (2016) · Psychological Review · doi:10.1037/rev0000033 · Cited by 919 · see citing works

The Social Salience Hypothesis of Oxytocin

Shamay-Tsoory, S. G., & Abu-Akel, A. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.07.020 · Cited by 904 · see citing works

Sex-specific transcriptional signatures in human depression

Labonté, B., Engmann, O., Purushothaman, I., Menard, C., Wang, J., Tan, C., Scarpa, J. R., Moy, G., Loh, Y.-H. E., Cahill, M., et al. (2017) · Nature Medicine · doi:10.1038/nm.4386 · Cited by 748 · see citing works

Sex Differences in Animal Models: Focus on Addiction

Becker, J. B., & Koob, G. F. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.011163 · Cited by 725 · see citing works

Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder

(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.5.624 · Cited by 721 · see citing works

Work stress precipitates depression and anxiety in young, working women and men

MELCHIOR, M., CASPI, A., MILNE, B. J., DANESE, A., POULTON, R., & MOFFITT, T. E. (2007) · Psychological Medicine · doi:10.1017/s0033291707000414 · Cited by 691 · see citing works

De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder.

Orr, S. P., Metzger, L. J., Lasko, N. B., Macklin, M. L., Peri, T., & Pitman, R. K. (2000) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.109.2.290 · Cited by 653 · see citing works

Back to the future: The organizational-activational hypothesis adapted to puberty and adolescence

Schulz, K. M., Molenda-Figueira, H. A., & Sisk, C. L. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.03.010 · Cited by 587 · see citing works

Attention and executive functions in remitted major depression patients

Paelecke-Habermann, Y., Pohl, J., & Leplow, B. (2005) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.09.006 · Cited by 487 · see citing works

Avoidance and depression: the construction of the Cognitive–Behavioral Avoidance Scale

Ottenbreit, N. D., & Dobson, K. S. (2004) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(03)00140-2 · Cited by 457 · see citing works

Gender differences in social anxiety disorder: A review

Asher, M., Asnaani, A., & Aderka, I. M. (2017) · Clinical Psychology Review · doi:10.1016/j.cpr.2017.05.004 · Cited by 457 · see citing works

Estrous cycle phase and gonadal hormones influence conditioned fear extinction

Milad, M. R., Igoe, S. A., Lebron-Milad, K., & Novales, J. E. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.09.011 · Cited by 417 · see citing works

The role of the nucleus accumbens and rostral anterior cingulate cortex in anhedonia: integration of resting EEG, fMRI, and volumetric techniques

Wacker, J., Dillon, D. G., & Pizzagalli, D. A. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.01.058 · Cited by 405 · see citing works

The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice

Lukas, M., Toth, I., Reber, S. O., Slattery, D. A., Veenema, A. H., & Neumann, I. D. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.95 · Cited by 403 · see citing works

Cognitive processes during fear acquisition and extinction in animals and humans: Implications for exposure therapy of anxiety disorders

Hofmann, S. G. (2008) · Clinical Psychology Review · doi:10.1016/j.cpr.2007.04.009 · Cited by 397 · see citing works

Sex differences in anxiety and emotional behavior

Donner, N. C., & Lowry, C. A. (2013) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1271-7 · Cited by 379 · see citing works

Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons

Nakajima, M., Görlich, A., & Heintz, N. (2014) · Cell · doi:10.1016/j.cell.2014.09.020 · Cited by 262 · see citing works

A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors

Li, K., Nakajima, M., Ibañez-Tallon, I., & Heintz, N. (2016) · Cell · doi:10.1016/j.cell.2016.08.067 · Cited by 234 · see citing works

Oxytocin receptors in the anteromedial bed nucleus of the stria terminalis promote stress-induced social avoidance in female California mice

Duque-Wilckens, N., Steinman, M. Q., Busnelli, M., Chini, B., Yokoyama, S., Pham, M., Laredo, S. A., Hao, R., Perkeybile, A. M., Minie, V. A., et al. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.08.024 · Cited by 181 · see citing works

Females do not express learned helplessness like males do

Dalla, C., Edgecomb, C., Whetstone, A. S., & Shors, T. J. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301533 · Cited by 174 · see citing works

Controllable versus uncontrollable stressors bi-directionally modulate conditioned but not innate fear

Baratta, M. V., Christianson, J. P., Gomez, D. M., Zarza, C. M., Amat, J., Masini, C. V., Watkins, L. R., & Maier, S. F. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.03.042 · Cited by 156 · see citing works

Behavioral control blunts reactions to contemporaneous and future adverse events: Medial prefrontal cortex plasticity and a corticostriatal network

Maier, S. F. (2015) · Neurobiology of Stress · doi:10.1016/j.ynstr.2014.09.003 · Cited by 143 · see citing works

Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance

Duque-Wilckens, N., Torres, L. Y., Yokoyama, S., Minie, V. A., Tran, A. M., Petkova, S. P., Hao, R., Ramos-Maciel, S., Rios, R. A., Jackson, K., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2011890117 · Cited by 139 · see citing works

Sex Differences in Anxiety Disorders: A Review

University of Texas Health Science Center at Houston, & Jalnapurkar, I. (2018) · Psychiatry, Depression & Anxiety · doi:10.24966/pda-0150/100011 · Cited by 139 · see citing works

Higher Levels of Basal Serial CSF Cortisol in Combat Veterans With Posttraumatic Stress Disorder

Baker, D. G., Ekhator, N. N., Kasckow, J. W., Dashevsky, B., Horn, P. S., Bednarik, L., & Geracioti, T. D. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.5.992 · Cited by 135 · see citing works

Sex differences in stress regulation of arousal and cognition

Bangasser, D. A., Eck, S. R., Telenson, A. M., & Salvatore, M. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2017.09.025 · Cited by 133 · see citing works

Sex-specific effects of stress on oxytocin neurons correspond with responses to intranasal oxytocin

Steinman, M. Q., Duque-Wilckens, N., Greenberg, G. D., Hao, R., Campi, K. L., Laredo, S. A., Laman-Maharg, A., Manning, C. E., Doig, I. E., Lopez, E. M., et al. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.10.007 · Cited by 131 · see citing works

Neural changes in extinction recall following prolonged exposure treatment for PTSD: A longitudinal fMRI study

Helpman, L., Marin, M.-F., Papini, S., Zhu, X., Sullivan, G. M., Schneier, F., Neria, M., Shvil, E., Malaga Aragon, M. J., Markowitz, J. C., et al. (2016) · NeuroImage: Clinical · doi:10.1016/j.nicl.2016.10.007 · Cited by 121 · see citing works

Sex differences in stress-induced social withdrawal: Independence from adult gonadal hormones and inhibition of female phenotype by corncob bedding

Trainor, B. C., Takahashi, E. Y., Campi, K. L., Florez, S. A., Greenberg, G. D., Laman-Maharg, A., Laredo, S. A., Orr, V. N., Silva, A. L., & Steinman, M. Q. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.01.011 · Cited by 86 · see citing works

Effects of photoperiod and experience on aggressive behavior in female California mice

Silva, A. L., Fry, W. H. D., Sweeney, C., & Trainor, B. C. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.12.038 · Cited by 76 · see citing works

Meeting report: can we make animal models of human mental illness?

Monteggia, L. M., Heimer, H., & Nestler, E. J. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.02.010 · Cited by 60 · see citing works

Gender Differences in Sleep During the Aftermath of Trauma and the Development of Posttraumatic Stress Disorder

Kobayashi, I., & Mellman, T. A. (2012) · Behavioral Sleep Medicine · doi:10.1080/15402002.2011.654296 · Cited by 49 · see citing works

The menace of obesity to depression and anxiety prevalence

Fulton, S., Décarie-Spain, L., Fioramonti, X., Guiard, B., & Nakajima, S. (2022) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2021.10.005 · Cited by 441 · see citing works

Factors associated with gender and sex differences in anxiety prevalence and comorbidity: A systematic review

Farhane-Medina, N. Z., Luque, B., Tabernero, C., & Castillo-Mayén, R. (2022) · Science Progress · doi:10.1177/00368504221135469 · Cited by 409 · see citing works

Social media as an incubator of personality and behavioral psychopathology: Symptom and disorder authenticity or psychosomatic social contagion?

Haltigan, J. D., Pringsheim, T. M., & Rajkumar, G. (2023) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2022.152362 · Cited by 92 · see citing works

Sexual differentiation of neural mechanisms of stress sensitivity during puberty

Wright, E. C., Luo, P. X., Zakharenkov, H. C., Serna Godoy, A., Lake, A. A., Prince, Z. D., Sekar, S., Culkin, H. I., Ramirez, A. V., Dwyer, T., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2306475120 · Cited by 34 · see citing works

Anxiety and Depression Symptoms among Youth Survivors of Childhood Sexual Abuse: A Network Analysis

Li, J., Jin, Y., Xu, S., Luo, X., Wilson, A., Li, H., Wang, X., Sun, X., & Wang, Y. (2023) · BMC Psychology · doi:10.1186/s40359-023-01275-3 · Cited by 29 · see citing works

An allostatic epigenetic memory on chromatin footprints after double-hit acute stress

Caradonna, S. G., Paul, M. R., & Marrocco, J. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100475 · Cited by 13 · see citing works

Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression

Corvo, C., Mendez-David, I., Goutal, S., Saba, W., Bottlaender, M., Caillé, F., Hen, R., Colle, R., Corruble, E., Tournier, N., et al. (2025) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.4c00621 · Cited by 7 · see citing works