Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disorders

Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359

Neurotoxic reactive astrocytes are induced by activated microglia

Liddelow, S. A., Guttenplan, K. A., Clarke, L. E., Bennett, F. C., Bohlen, C. J., Schirmer, L., Bennett, M. L., Münch, A. E., Chung, W.-S., Peterson, T. C., et al. (2017) · Nature · doi:10.1038/nature21029 · Cited by 7,971

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Iliff, J. J., Wang, M., Liao, Y., Plogg, B. A., Peng, W., Gundersen, G. A., Benveniste, H., Vates, G. E., Deane, R., Goldman, S. A., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003748 · Cited by 5,824

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., DeTeresa, R., Hill, R., Hansen, L. A., & Katzman, R. (1991) · Annals of Neurology · doi:10.1002/ana.410300410 · Cited by 4,397

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

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Glutamate uptake

Danbolt, N. C. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00067-8 · Cited by 4,227

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

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The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313

Single-cell transcriptomic analysis of Alzheimer’s disease

Mathys, H., Davila-Velderrain, J., Peng, Z., Gao, F., Mohammadi, S., Young, J. Z., Menon, M., He, L., Abdurrob, F., Jiang, X., et al. (2019) · Nature · doi:10.1038/s41586-019-1195-2 · Cited by 2,568

Reactive astrocyte nomenclature, definitions, and future directions

Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-020-00783-4 · Cited by 2,513

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

Loh, J. S., Mak, W. Q., Tan, L. K. S., Ng, C. X., Chan, H. H., Yeow, S. H., Foo, J. B., Ong, Y. S., How, C. W., & Khaw, K. Y. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01743-1 · Cited by 1,193

Alzheimer’s disease: insights into pathology, molecular mechanisms, and therapy

Zheng, Q., & Wang, X. (2024) · Protein & Cell · doi:10.1093/procel/pwae026 · Cited by 483

Current understanding of the Alzheimer’s disease-associated microbiome and therapeutic strategies

Seo, D.-O., & Holtzman, D. M. (2024) · Experimental & Molecular Medicine · doi:10.1038/s12276-023-01146-2 · Cited by 259

Mitochondrial diseases: from molecular mechanisms to therapeutic advances

Wen, H., Deng, H., Li, B., Chen, J., Zhu, J., Zhang, X., Yoshida, S., & Zhou, Y. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02044-3 · Cited by 284

Astrocyte morphology

Baldwin, K. T., Murai, K. K., & Khakh, B. S. (2023) · Trends in Cell Biology · doi:10.1016/j.tcb.2023.09.006 · Cited by 237

Targeting synapse function and loss for treatment of neurodegenerative diseases

Dejanovic, B., Sheng, M., & Hanson, J. E. (2023) · Nature Reviews Drug Discovery · doi:10.1038/s41573-023-00823-1 · Cited by 177

Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum

Mätlik, K., Baffuto, M., Kus, L., Deshmukh, A. L., Davis, D. A., Paul, M. R., Carroll, T. S., Caron, M., Masson, J., Pearson, C. E., et al. (2024) · Nature Genetics · doi:10.1038/s41588-024-01653-6 · Cited by 151

The Glutamate/ GABA ‐Glutamine Cycle: Insights, Updates, and Advances

Andersen, J. V. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70029 · Cited by 170

Metabolic Syndrome as a Risk Factor for Alzheimer’s Disease: A Focus on Insulin Resistance

Ezkurdia, A., Ramírez, M. J., & Solas, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054354 · Cited by 160

Astrocyte metabolism and signaling pathways in the CNS

Zhang, Y.-M., Qi, Y., Gao, Y.-N., Chen, W.-G., Zhou, T., Zang, Y., & Li, J. X. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1217451 · Cited by 152

Huntington’s Disease: Complex Pathogenesis and Therapeutic Strategies

Tong, H., Yang, T., Xu, S., Li, X., Liu, L., Zhou, G., Yang, S., Yin, S., Li, X., & Li, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073845 · Cited by 142

The immunological perspective of major depressive disorder: unveiling the interactions between central and peripheral immune mechanisms

Jiao, W., Lin, J., Deng, Y., Ji, Y., Liang, C., Wei, S., Xi, J., & Yan, F. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03312-3 · Cited by 132

Alpha Synuclein: Neurodegeneration and Inflammation

Forloni, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065914 · Cited by 116

Blood–Brain Barrier Breakdown in Neuroinflammation: Current In Vitro Models

Brandl, S., & Reindl, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612699 · Cited by 97

Amyloid-β and Tau in Alzheimer’s disease: pathogenesis, mechanisms, and interplay

Abdulkhaliq, A. A., Kim, B., Almoghrabi, Y. M., Khan, J., Ajoolabady, A., Ren, J., Bahijri, S., Tuomilehto, J., Borai, A., & Pratico, D. (2026) · Cell Death & Disease · doi:10.1038/s41419-025-08186-8 · Cited by 87

Large-Scale Integration of Single-Cell RNA-Seq Data Reveals Astrocyte Diversity and Transcriptomic Modules across Six Central Nervous System Disorders

Qian, Z., Qin, J., Lai, Y., Zhang, C., & Zhang, X. (2023) · Biomolecules · doi:10.3390/biom13040692 · Cited by 81

The cGAS-STING pathway drives neuroinflammation and neurodegeneration via cellular and molecular mechanisms in neurodegenerative diseases

Zhang, Y., Zou, M., Wu, H., Zhu, J., & Jin, T. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106710 · Cited by 75

Tackling the glial scar in spinal cord regeneration: new discoveries and future directions

Shafqat, A., Albalkhi, I., Magableh, H. M., Saleh, T., AlKattan, K. M., & Yaqinuddin, A. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1180825 · Cited by 71

α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis

Wang, P., Lan, G., Xu, B., Yu, Z., Tian, C., Lei, X., Meissner, W. G., Feng, T., Yang, Y., & Zhang, J. (2023) · Translational Neurodegeneration · doi:10.1186/s40035-023-00372-y · Cited by 66

The Amyloid-Beta Clearance: From Molecular Targets to Glial and Neural Cells

Cai, W., Wu, T., & Chen, N. (2023) · Biomolecules · doi:10.3390/biom13020313 · Cited by 69

Extracellular Vesicles in the Central Nervous System: A Novel Mechanism of Neuronal Cell Communication

Filannino, F. M., Panaro, M. A., Benameur, T., Pizzolorusso, I., & Porro, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031629 · Cited by 60

NRF2 Deficiency Promotes Ferroptosis of Astrocytes Mediated by Oxidative Stress in Alzheimer’s Disease

Tang, Z., Chen, Z., Guo, M., Peng, Y., Xiao, Y. C., Guan, Z.-Z., Ni, R., & Qi, X. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04023-9 · Cited by 60

Gut microbiota changes in patients with Alzheimer’s disease spectrum based on 16S rRNA sequencing: a systematic review and meta-analysis

Li, H., Cui, X., Lin, Y., Huang, F., Tian, A., & Zhang, R. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1422350 · Cited by 65

Astrocytes in aging

Labarta-Bajo, L., & Allen, N. J. (2025) · Neuron · doi:10.1016/j.neuron.2024.12.010 · Cited by 62

Advancements in Human Embryonic Stem Cell Research: Clinical Applications and Ethical Issues

Park, S. J., Kim, Y. Y., Han, J. Y., Kim, S. W., Kim, H., & Ku, S. (2024) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-024-00627-3 · Cited by 53

The Niemann-Pick type diseases – A synopsis of inborn errors in sphingolipid and cholesterol metabolism

Pfrieger, F. W. (2023) · Progress in Lipid Research · doi:10.1016/j.plipres.2023.101225 · Cited by 54

Microglia and Astrocytes in Amyotrophic Lateral Sclerosis: Disease-Associated States, Pathological Roles, and Therapeutic Potential

You, J., Youssef, M., Santos, J. R., Lee, J., & Park, J. (2023) · Biology · doi:10.3390/biology12101307 · Cited by 60

Cytosolic calcium: Judge, jury and executioner of neurodegeneration in Alzheimer's disease and beyond

Webber, E. K., Fivaz, M., Stutzmann, G. E., & Griffioen, G. (2023) · Alzheimer's & Dementia · doi:10.1002/alz.13065 · Cited by 50

Current Anti-Amyloid-β Therapy for Alzheimer’s Disease Treatment: From Clinical Research to Nanomedicine

Zhao, Z., Liu, Y., Ruan, S., & Hu, Y. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s444115 · Cited by 49

Crosstalk between Oxidative Stress and Inflammation Caused by Noise and Air Pollution—Implications for Neurodegenerative Diseases

Kuntić, M., Hahad, O., Münzel, T. F., & Daiber, A. (2024) · Antioxidants · doi:10.3390/antiox13030266 · Cited by 53

Astrocytes in selective vulnerability to neurodegenerative disease

Zimmer, T. S., Orr, A. L., & Orr, A. G. (2024) · Trends in Neurosciences · doi:10.1016/j.tins.2024.02.008 · Cited by 57

Different pieces of the same puzzle: a multifaceted perspective on the complex biological basis of Parkinson’s disease

Müller-Nedebock, A. C., Dekker, M. C. J., Farrer, M. J., Hattori, N., Lim, S., Mellick, G. D., Rektorová, I., Salama, M., Schuh, A. F. S., Stoessl, A. J., et al. (2023) · npj Parkinson s Disease · doi:10.1038/s41531-023-00535-8 · Cited by 49

Research progress in the molecular mechanism of ferroptosis in Parkinson's disease and regulation by natural plant products

Yang, K., Zeng, L., Zeng, J., Deng, Y., Wang, S., Xu, H., He, Q., Yuan, M., Luo, Y., Ge, A., et al. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102063 · Cited by 46

Neurological disorders after severe pneumonia are associated with translocation of endogenous bacteria from the lung to the brain

Ma, Q., Yao, C., Wu, Y., Wang, H., Fan, Q., Yang, Q., Xu, J., Dai, H., Zhang, Y., Xu, F., et al. (2023) · Science Advances · doi:10.1126/sciadv.adi0699 · Cited by 45

Astrocyte and oligodendrocyte pathology in Alzheimer's disease

Ziar, R., Tesar, P. J., & Clayton, B. L. L. (2025) · Neurotherapeutics · doi:10.1016/j.neurot.2025.e00540 · Cited by 47

Astrocytes: integrators of arousal state and sensory context

Rasmussen, R. N., Asiminas, A., Carlsen, E. M., Kjærby, C., & Smith, N. (2023) · Trends in Neurosciences · doi:10.1016/j.tins.2023.03.003 · Cited by 47

The neuron–astrocyte metabolic unit as a cornerstone of brain energy metabolism in health and disease

Bolaños, J. P., & Magistretti, P. J. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01404-9 · Cited by 46

Inflammasomes in neurodegenerative diseases

Wang, Q., Yang, S., Zhang, X., Zhang, S., Chen, L., Wang, W., Chen, N., & Yan, J. (2024) · Translational Neurodegeneration · doi:10.1186/s40035-024-00459-0 · Cited by 47

Microglia regulate neuronal activity via structural remodeling of astrocytes

Gu, N., Makashova, O. E., Laporte, C., Chen, C. Q., Li, B., Chevillard, P., Lean, G., Yang, J., Wong, C., Fan, J., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.07.024 · Cited by 46

The Inflammatory Puzzle: Piecing together the Links between Neuroinflammation and Amyotrophic Lateral Sclerosis

He, D., Xu, Y. C., Liu, M., & Cui, L. (2023) · Aging and Disease · doi:10.14336/ad.2023.0519 · Cited by 44

Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation

Andrade, M. F., Comin, C. H., Dyken, P. C. V., Ouellette, J., Raman‐Nair, J., Blakeley, N., Liu, Q. Y., Leclerc, S., Pan, Y., Liu, Z., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-40682-3 · Cited by 42

Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine

Summers, R. A., Fagiani, F., Rowitch, D. H., Absinta, M., & Reich, D. S. (2024) · Trends in Immunology · doi:10.1016/j.it.2024.08.004 · Cited by 39

DNA Damage-Mediated Neurotoxicity in Parkinson’s Disease

Wang, Z., Li, Y., Pu, J., & Zhang, B. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076313 · Cited by 43

Astrocytes: The Stars in Neurodegeneration?

Dittlau, K. S., & Freude, K. (2024) · Biomolecules · doi:10.3390/biom14030289 · Cited by 39

The toxic metal hypothesis for neurological disorders

Pamphlett, R., & Bishop, D. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1173779 · Cited by 44

Parthenolide ameliorates 3-nitropropionic acid-induced Huntington’s disease-like aberrations via modulating NLRP3 inflammasome, reducing microglial activation and inducing astrocyte shifting

Noureldeen, M. E., Shahin, N. N., Amin, H. A. A., El‐Sawalhi, M. M., & Ghaiad, H. R. (2024) · Molecular Medicine · doi:10.1186/s10020-024-00917-5 · Cited by 37

Astrocytes release ATP/ADP and glutamate in flashes via vesicular exocytosis

Li, H., Zhao, Y., Dai, R., Geng, P., Weng, D., Wu, W., Yu, F., Lin, R., Wu, Z., Li, Y., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02851-8 · Cited by 41

NADPH oxidase 4 (NOX4) as a biomarker and therapeutic target in neurodegenerative diseases

Boonpraman, N., & Yi, S. S. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.390973 · Cited by 37

Modulating Neuroinflammation as a Prospective Therapeutic Target in Alzheimer’s Disease

Lee, E., & Chang, Y. (2025) · Cells · doi:10.3390/cells14030168 · Cited by 39

Lysosomal acidification impairment in astrocyte-mediated neuroinflammation

Zeng, J., Indajang, J., Pitt, D., & Lo, C. H. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03410-w · Cited by 44

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

Barnett, D., Zimmer, T. S., Booraem, C., Palaguachi, F., Meadows, S. M., Xiao, H., Wong, M. Y., Luo, W., Gan, L., Chouchani, E. T., et al. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01390-y · Cited by 41

Lactylation: A Novel Post-Translational Modification with Clinical Implications in CNS Diseases

Liu, J., Zhao, F., & Qu, Y. (2024) · Biomolecules · doi:10.3390/biom14091175 · Cited by 37

Amyotrophic Lateral Sclerosis Pathoetiology and Pathophysiology: Roles of Astrocytes, Gut Microbiome, and Muscle Interactions via the Mitochondrial Melatonergic Pathway, with Disruption by Glyphosate-Based Herbicides

Anderson, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010587 · Cited by 36

Neuroprotective effects of gemfibrozil in neurological disorders: Focus on inflammation and molecular mechanisms

Ivraghi, M. S., Zamanian, M. Y., Gupta, R., Achmad, H., Alsaab, H. O., Hjazi, A. M., Romero‐Parra, R. M., Alwaily, E. R., Hussien, B. M., & Hakimizadeh, E. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14473 · Cited by 34

Neural Metabolic Networks: Key Elements of Healthy Brain Function

Madrer, N., Perera, N. D., Uccelli, N. A., Abbondanza, A., Andersen, J. V., Carsana, E. V., Demmings, M. D., Fernandez, R. F., de Fragas, M. G., Gbadamosi, I., et al. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70084 · Cited by 37

Disease-relevant upregulation of P2Y1 receptor in astrocytes enhances neuronal excitability via IGFBP2

Shigetomi, E., Suzuki, H., Hirayama, Y. J., Sano, F., Nagai, Y., Yoshihara, K., Koga, K., Tateoka, T., Yoshioka, H., Shinozaki, Y., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50190-7 · Cited by 33

Single-atom nanozyme liposome-integrated microneedles for in situ drug delivery and anti-inflammatory therapy in Parkinson’s disease

Liu, Y., Liu, Y., Shi, P., Hu, X., Fan, X., Wu, Y., Pan, J., Bai, Q., & Li, Q. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02924-4 · Cited by 36

Activating astrocytic α2A adrenoceptors in hippocampus reduces glutamate toxicity to attenuate sepsis-associated encephalopathy in mice

Mei, B., Xu, X., Weng, J., Yang, Y., Wang, P., Qiu, G., Zhang, C., Zhang, Q., Lu, Y., & Liu, X. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.02.005 · Cited by 35

Interaction of high-fat diet and brain trauma alters adipose tissue macrophages and brain microglia associated with exacerbated cognitive dysfunction

Henry, R. J., Barrett, J. P., Vaida, M. L., Khan, N., Makarevich, O. D., Ritzel, R. M., Faden, A. I., & Stoica, B. A. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03107-6 · Cited by 35

The “molecular soldiers” of the CNS: astrocytes, a comprehensive review on their roles and molecular signatures

Rupareliya, V. P., Singh, A. A., Butt, A. M., A, H., & Kumar, H. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176048 · Cited by 29

Navigating the metabolic maze: anomalies in fatty acid and cholesterol processes in Alzheimer’s astrocytes

Zhang, X., Chen, C., & Liu, Y. (2024) · Alzheimer's Research & Therapy · doi:10.1186/s13195-024-01430-x · Cited by 34

Astrocyte-derived clusterin disrupts glial physiology to obstruct remyelination in mouse models of demyelinating diseases

Chen, C., Shu, Y., Yan, C., Li, H., Huang, Z., Shen, S., Liu, C., Jiang, Y., Huang, S., Wang, Z., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-52142-7 · Cited by 33

Preserving cognitive function in patients with Alzheimer's disease: The Alzheimer's disease neuroprotection research initiative (ADNRI)

Liu, J., van Beusekom, H. M. M., Bu, X., Chen, G., Rosado-de-Castro, P. H., Chen, X., Chen, X., Clarkson, A. N., Farr, T. D., Fu, Y., et al. (2023) · Neuroprotection/Neuroprotection (Chichester, England. Print) · doi:10.1002/nep3.23 · Cited by 32

Neuroinflammatory Proteins in Huntington’s Disease: Insights into Mechanisms, Diagnosis, and Therapeutic Implications

Li, X., Tong, H., Xu, S., Zhou, G., Yang, T., Yin, S., Yang, S., Li, X., & Li, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111787 · Cited by 35

Astrocyte and L-lactate in the anterior cingulate cortex modulate schema memory and neuronal mitochondrial biogenesis

Akter, M., Hasan, M., Ramkrishnan, A. S., Zheng, X., Iqbal, Z., Fu, Z., Lei, Z., Karim, A., & Li, Y. (2023) · eLife · doi:10.7554/elife.85751 · Cited by 28

Neuronal DAMPs exacerbate neurodegeneration via astrocytic RIPK3 signaling

Chang, N. P., DaPrano, E. M., Lindman, M., Estevez, I., Chou, T.-W., Evans, W. R., Nissenbaum, M., McCourt, M., Alzate, D., Atkins, C., et al. (2024) · JCI Insight · doi:10.1172/jci.insight.177002 · Cited by 28

The role of adenosine A2A receptors in Alzheimer's disease and tauopathies

Launay, A., Nebie, O., Shankara, J. V., Lebouvier, T., Buée, L., Faivre, É., & Blum, D. L. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109379 · Cited by 29

Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting

Barnett, D., Bohmbach, K., Grelot, V., Charlet, A., Dallérac, G. M., Ju, Y. H., Nagai, J., & Orr, A. G. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.1376-23.2023 · Cited by 27

The Role of Atypical Chemokine Receptors in Neuroinflammation and Neurodegenerative Disorders

Lindsay, H. G., Hendrix, C. J., Murcia, J. D. G., Haynie, C., & Weber, K. S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216493 · Cited by 29

Role of Glial Cells in Neuronal Function, Mood Disorders, and Drug Addiction

Tizabi, Y., Getachew, B., Hauser, S. R., Tsytsarev, V., Manhães, A. C., & da Silva, V. D. A. (2024) · Brain Sciences · doi:10.3390/brainsci14060558 · Cited by 27

Astrocytes in Post-Stroke Depression: Roles in Inflammation, Neurotransmission, and Neurotrophin Signaling

Jing, D., Hou, X., Guo, X., Zhao, X., Zhang, K., Zhang, J., Kan, C., Han, F., Liu, J., & Sun, X. (2023) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-023-01386-w · Cited by 27

Novel Insights into Parkin–Mediated Mitochondrial Dysfunction and “Mito-Inflammation” in α-Synuclein Toxicity. The Role of the cGAS–STING Signalling Pathway

Gąssowska-Dobrowolska, M., Olech-Kochańczyk, G., Culmsee, C., & Adamczyk, A. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s468609 · Cited by 29

Clusterin is a Potential Therapeutic Target in Alzheimer’s Disease

Palihati, N., Tang, Y., Yin, Y., Yu, D., Liu, G., Quan, Z., Ni, J., Yan, Y., & Qing, H. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03801-1 · Cited by 25

Making tracks: microglia and the extracellular matrix

Wareham, L. K., & Calkins, D. J. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00898-x · Cited by 37

Human Glial Cells as Innovative Targets for the Therapy of Central Nervous System Pathologies

Magni, G., Riboldi, B., & Ceruti, S. (2024) · Cells · doi:10.3390/cells13070606 · Cited by 30

Neuroprotective effect of Withania somnifera leaves extract nanoemulsion against penconazole-induced neurotoxicity in albino rats via modulating TGF-β1/Smad2 signaling pathway

Abomosallam, M., Hendam, B. M., Abdallah, A. A., Refaat, R., & El-Hak, H. N. G. (2024) · Inflammopharmacology · doi:10.1007/s10787-024-01461-8 · Cited by 28

Intercellular Adhesion Molecule 1 (ICAM-1): An Inflammatory Regulator with Potential Implications in Ferroptosis and Parkinson’s Disease

Miller, M. R., Landis, H. E., Miller, R. E., & Tizabi, Y. (2024) · Cells · doi:10.3390/cells13181554 · Cited by 26

Calcium signaling hypothesis: A non-negligible pathogenesis in Alzheimer’s disease

Wang, M., Zhang, H., Liang, J., Huang, J., Wu, T., & Chen, N. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.01.007 · Cited by 29

Semaglutide improves cognitive function and neuroinflammation in APP/PS1 transgenic mice by activating AMPK and inhibiting TLR4/NF-κB pathway

Zhai, Y., Lu, K., Yuan, Y., Zhang, Z., Xue, L., Zhao, F., Xu, X., & Wang, H. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251329439 · Cited by 24

Striatal astrocytic A2A-D2 receptor-receptor interactions and their role in neuropsychiatric disorders

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The role of astrocytes from synaptic to non-synaptic plasticity

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