Tidal and diel orchestration of behaviour and gene expression in an intertidal mollusc
Open accessAbstract
Intertidal inhabitants are exposed to the 24-hour solar day, and the 12.4 hour rising and falling of the tides. One or both of these cycles govern intertidal organisms' behaviour and physiology, yet little is known about the molecular clockworks of tidal rhythmicity. Here, we show that the limpet Cellana rota exhibits robust tidally rhythmic behaviour and gene expression. We assembled a de-novo transcriptome, identifying novel tidal, along with known circadian clock genes. Surprisingly, most of the putative circadian clock genes, lack a typical rhythmicity. We identified numerous tidally rhythmic genes and pathways commonly associated with the circadian clock. We show that not only is the behaviour of an intertidal organism in tune with the tides, but so too are many of its genes and pathways. These findings highlight the plasticity of biological timekeeping in nature, strengthening the growing notion that the role of 'canonical' circadian clock genes may be more fluid than previously thought, as exhibited in an organism which has evolved in an environment where tidal oscillations are the dominant driving force.
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Taking all above findings together might start to indicate that the circadian clockwork could be more plastic than previously thought and capable to adjust to the environmental cycle(s) most relevant for a given species.
“Taking all above findings together might start to indicate that the circadian clockwork could be more plastic than previously thought and capable to adjust to the environmental cycle(s) most relevant for a given species [53,54,57].”
From The Still Dark Side of the Moon: Molecular Mechanisms of Lunar-Controlled Rhythms and Clocks (2020) · cites this paper as [57]
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- Authors
- Schnytzer, Y., Simon-Blecher, N., Li, J., Waldman Ben-Asher, H., Salmon-Divon, M., Achituv, Y., Hughes, M. E., & Levy, O.
- Affiliations
- Marine Biological Laboratory (US)
- Washington University in St. Louis (US)
- Bar-Ilan University (IL)
- Corresponding author
- Schnytzer, Y.
- Levy, O.
- Venue
- Scientific Reports
- Published
- 2018-03-20
- Volume
- 8
- Issue
- 1
- Pages
- 4917-4917
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC5861051
- OpenAlex
- W2796000522
- Cited by
- 58
- References
- 70
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 5 · 2023: 8 · 2022: 14 · 2021: 7 · 2020: 7 · 2019: 7 · 2018: 2
- FWCI
- 3.23
- Type
- journal article
- Language
- en
- Update notices
- correction (2019-07-17)
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Digital Commons@Becker (Washington University School of Medicine) (submittedVersion, cc-by)
- Open Access Server of the Woods Hole Scientific Community (Woods Hole Scientific Community) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Bar-Ilan University
- Israeli Centers for Research Excellence (41/11)
- Planning and Budgeting Committee of the Council for Higher Education of Israel (41/11)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Physical Sciences › Environmental Science › Ecology › Physiological and biochemical adaptations
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Marine Invertebrate Physiology and Ecology
- Keywords
- tidal rhythms, clock genes, limpets, gene expression rhythms, de novo transcriptome, biological timekeeping, diel rhythm
- MeSH terms
- Adaptation, Biological, Animals, Biological Clocks, Circadian Rhythm, Biological Evolution, Signal Transduction, Gastropoda, Tidal Waves, Transcriptome
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