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Multipotent mesenchymal stromal cell therapy in renal disease and kidney transplantation

Reinders, M. E. J., Fibbe, W. E., & Rabelink, T. J. (2009) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfp552 · Cited by 94 · see citing works

Chemokine, vascular and therapeutic effects of combination Simvastatin and BMSC treatment of stroke

Cui, X., Chopp, M., Zacharek, A., Roberts, C. J., Lü, M., Savant‐Bhonsale, S., & Chen, J. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.06.012 · Cited by 93 · see citing works

Nitric Oxide Donor Upregulation of Stromal Cell-Derived Factor-1/Chemokine (CXC Motif) Receptor 4 Enhances Bone Marrow Stromal Cell Migration into Ischemic Brain After Stroke

Cui, X., Chen, J., Zacharek, A., Li, Y., Roberts, C. J., Kapke, A., Savant‐Bhonsale, S., & Chopp, M. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0169 · Cited by 87 · see citing works

Blood–spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast‐enhanced MRI

Cohen, D. M., Patel, C. B., Ahobila‐Vajjula, P., Sundberg, L. M., Chacko, T., Liu, S., & Narayana, P. A. (2009) · NMR in Biomedicine · doi:10.1002/nbm.1343 · Cited by 96 · see citing works

Review of Mesenchymal Stem Cells and Tumors: Executioner or Coconspirator?

Feng, B., & Chen, L. (2009) · Cancer Biotherapy and Radiopharmaceuticals · doi:10.1089/cbr.2009.0652 · Cited by 83 · see citing works

Coexpression of Angiopoietin-1 with VEGF Increases the Structural Integrity of the Blood–Brain Barrier and Reduces Atrophy Volume

Shen, F., Walker, E. J., Jiang, L., Degos, V., Li, J., Sun, B., Heriyanto, F., Young, W. L., & Su, H. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2011.97 · Cited by 82 · see citing works

The contribution of β-amyloid, Tau and α-synuclein to blood–brain barrier damage in neurodegenerative disorders

Wu, Y., Bogale, T. A., Koıstınaho, J., Pizzi, M., Rõlova, T., & Bellucci, A. (2024) · Acta Neuropathologica · doi:10.1007/s00401-024-02696-z · Cited by 81 · see citing works

Regeneration of the ischemic brain by engineered stem cells: Fuelling endogenous repair processes

van Velthoven, C. T. J., Kavelaars, A., van Bel, F., & Heijnen, C. J. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.03.003 · Cited by 75 · see citing works

The role of astrocytes in mediating exogenous cell‐based restorative therapy for stroke

Li, Y., Liu, Z., Xin, H., & Chopp, M. (2013) · Glia · doi:10.1002/glia.22585 · Cited by 76 · see citing works

Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites

Pischiutta, F., Brunelli, L., Romele, P., Silini, A. R., Sammali, E., Paracchini, L., Marchini, S., Talamini, L., Bigini, P., Boncoraglio, G. B., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001864 · Cited by 77 · see citing works

Exosomes derived from bone marrow mesenchymal stem cells harvested from type two diabetes rats promotes neurorestorative effects after stroke in type two diabetes rats

Venkat, P., Zacharek, A., Landschoot‐Ward, J., Wang, F., Culmone, L., Chen, Z., Chopp, M., & Chen, J. (2020) · Experimental Neurology · doi:10.1016/j.expneurol.2020.113456 · Cited by 75 · see citing works

MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy

Marofi, F., Alexandrovna, K. I., Margiana, R., Bahramali, M., Suksatan, W., Abdelbasset, W. K., Chupradit, S., Nasimi, M., & Maashi, M. S. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02662-6 · Cited by 78 · see citing works

Single-Cell RNA-Seq of Bone Marrow-Derived Mesenchymal Stem Cells Reveals Unique Profiles of Lineage Priming

Freeman, B. T., Jung, J. P., & Ogle, B. M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136199 · Cited by 73 · see citing works

Mesenchymal stem cell-conditioned media ameliorate diabetic endothelial dysfunction by improving mitochondrial bioenergetics via the Sirt1/AMPK/PGC-1α pathway

Yuan, Y., Shi, M., Li, L., Liu, J., Chen, B., Chen, Y., An, X., Liu, S., Luo, R., Long, D., et al. (2016) · Clinical Science · doi:10.1042/cs20160235 · Cited by 70 · see citing works

Panaxatriol saponins promotes angiogenesis and enhances cerebral perfusion after ischemic stroke in rats

Hui, Z., Sha, D., Wang, S., Li, C.-S., Qian, J., Wang, J.-Q., Zhao, Y., Zhang, J., Cheng, H., Yang, H., et al. (2017) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-017-1579-5 · Cited by 71 · see citing works

Exosome-mediated amplification of endogenous brain repair mechanisms and brain and systemic organ interaction in modulating neurological outcome after stroke

Venkat, P., Chen, J., & Chopp, M. (2018) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x18782789 · Cited by 71 · see citing works

Characterization of a Novel Diarrheagenic Strain of Proteus mirabilis Associated With Food Poisoning in China

Gong, Z., Shi, X., Bai, F., He, X., Zhang, H., Li, Y., Wan, Y., Lin, Y., Qiu, Y., Chen, Q., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02810 · Cited by 70 · see citing works

Juxtacrine and Paracrine Interactions of Rat Marrow-Derived Mesenchymal Stem Cells, Muscle-Derived Satellite Cells, and Neonatal Cardiomyocytes with Endothelial Cells in Angiogenesis Dynamics

Rahbarghazi‬, R., Nassiri, S. M., Khazraiinia, P., Kajbafzadeh, A. M., Ahmadi, S. H., Mohammadi, E., Molazem, M., & Zamani‐Ahmadmahmudi, M. (2012) · Stem Cells and Development · doi:10.1089/scd.2012.0377 · Cited by 68 · see citing works

CXCR4/CXCR7 Molecular Involvement in Neuronal and Neural Progenitor Migration: Focus in CNS Repair

Merino, J. J., Bellver‐Landete, V., Oset‐Gasque, M. J., & Cubelos, B. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24695 · Cited by 65 · see citing works

Mesenchymal stromal cells pretreated with pro-inflammatory cytokines promote skin wound healing through VEGFC-mediated angiogenesis

Zhu, M., Chu, Y., Shang, Q., Zheng, Z., Li, Y., Cao, L., Chen, Y., Cao, J., Lee, O. K., Wang, Y., et al. (2020) · Stem Cells Translational Medicine · doi:10.1002/sctm.19-0241 · Cited by 67 · see citing works

MiR-126 Contributes to Human Umbilical Cord Blood Cell-Induced Neurorestorative Effects After Stroke in Type-2 Diabetic Mice

Chen, J., Ning, R., Zacharek, A., Cui, C., Cui, X., Yan, T., Venkat, P., Zhang, Y., & Chopp, M. (2015) · Stem Cells · doi:10.1002/stem.2193 · Cited by 67 · see citing works

Comparison of Bone Marrow Stromal Cells Derived From Stroke and Normal Rats for Stroke Treatment

Zacharek, A., Shehadah, A., Chen, J., Cui, X., Roberts, C. J., Lü, M., & Chopp, M. (2010) · Stroke · doi:10.1161/strokeaha.109.568881 · Cited by 67 · see citing works

What Choline Metabolism Can Tell Us About the Underlying Mechanisms of Fetal Alcohol Spectrum Disorders

Zeisel, S. H. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8165-5 · Cited by 66 · see citing works

Low-Dose Candesartan Enhances Molecular Mediators of Neuroplasticity and Subsequent Functional Recovery After Ischemic Stroke in Rats

Ishrat, T., Pillai, B. A., Soliman, S. M., Fouda, A. Y., Kozak, A., Johnson, M. H., Ergul, A., & Fagan, S. C. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8830-6 · Cited by 67 · see citing works

miR-145 Regulates Diabetes-Bone Marrow Stromal Cell-Induced Neurorestorative Effects in Diabetes Stroke Rats

Cui, C., Ye, X., Chopp, M., Venkat, P., Zacharek, A., Yan, T., Ning, R., Yu, P., Cui, G., & Chen, J. (2016) · Stem Cells Translational Medicine · doi:10.5966/sctm.2015-0349 · Cited by 66 · see citing works

Transplantation of Flk-1+ human bone marrow-derived mesenchymal stem cells promotes angiogenesis and neurogenesis after cerebral ischemia in rats

Bao, X., Feng, M., Wei, J., Han, Q., Zhao, H., Li, G., Zhu, Z., Xing, H., An, Y., Qin, C., et al. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07733.x · Cited by 64 · see citing works

Increasing Ang1/Tie2 expression by simvastatin treatment induces vascular stabilization and neuroblast migration after stroke

Chen, J., Cui, X., Zacharek, A., & Chopp, M. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00380.x · Cited by 65 · see citing works

Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury

Kumar, H., Choi, H., Jo, M., Joshi, H. P., Muttigi, M. S., Bonanomi, D., Kim, S. B., Ban, E., Kim, A., Lee, S.-H., et al. (2018) · Acta Neuropathologica Communications · doi:10.1186/s40478-018-0576-3 · Cited by 63 · see citing works

PKM2 regulates angiogenesis of VR‐EPCs through modulating glycolysis, mitochondrial fission, and fusion

Ren, R., Guo, J., Shi, J. Y., Tian, Y., Li, M., & Kang, H. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29549 · Cited by 62 · see citing works

Mesenchymal Stromal Cell Therapy for Solid Organ Transplantation

Reinders, M. E. J., van Kooten, C., Rabelink, T. J., & de Fijter, J. W. (2017) · Transplantation · doi:10.1097/tp.0000000000001879 · Cited by 61 · see citing works

Modulating Astrocyte Transition after Stroke to Promote Brain Rescue and Functional Recovery: Emerging Targets Include Rho Kinase

Abeysinghe, H. C. S., Phillips, E., Chin-Cheng, H., Beart, P. M., & Roulston, C. L. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17030288 · Cited by 59 · see citing works

Dexmedetomidine Attenuates Blood-Spinal Cord Barrier Disruption Induced by Spinal Cord Ischemia Reperfusion Injury in Rats

Fang, B., Li, X., Bi, B., Tan, W., Liu, G., Zhang, Y., & Ma, H. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000430107 · Cited by 55 · see citing works

Dietary supplementation with omega-3 polyunsaturated fatty acids robustly promotes neurovascular restorative dynamics and improves neurological functions after stroke

Zhang, W., Wang, H., Zhang, H., Leak, R. K., Shi, Y., Hu, X., Gao, Y., & Chen, J. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.03.005 · Cited by 57 · see citing works

Cell-Based and Exosome Therapy in Diabetic Stroke

Venkat, P., Chopp, M., & Chen, J. (2018) · Stem Cells Translational Medicine · doi:10.1002/sctm.18-0014 · Cited by 56 · see citing works

The three-phase enriched environment paradigm promotes neurovascular restorative and prevents learning impairment after ischemic stroke in rats

Zhan, Y., Li, M.-Z., Yang, L. J., Feng, X.-F., Lei, J., Zhang, N., Zhao, Y., & Zhao, H. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105091 · Cited by 55 · see citing works

Mesenchymal Stem Cells: Therapeutic Mechanisms for Stroke

Zhang, Y., Dong, N., Hong, H., Qi, J., Zhang, S., & Wang, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052550 · Cited by 55 · see citing works

Stem cell therapy for acute cerebral injury

Lemmens, R., & Steinberg, G. K. (2013) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000023 · Cited by 55 · see citing works

Therapeutic Benefit of Intravenous Transplantation of Mesenchymal Stem Cells After Experimental Subarachnoid Hemorrhage in Rats

Khalili, M. A., Anvari, M., Hekmatimoghaddam, S., Sadeghian‐Nodoushan, F., Fesahat, F., & Miresmaeili, S. M. (2011) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2010.10.005 · Cited by 53 · see citing works

Mesenchymal Stem/Stromal Cell Therapy in Blood–Brain Barrier Preservation Following Ischemia: Molecular Mechanisms and Prospects

Do, P. T., Wu, C.-C., Chiang, Y. H., Hu, C., & Chen, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221810045 · Cited by 53 · see citing works

Research developments in the neurovascular unit and the blood‑brain barrier (Review)

Gong, Y., Wu, M., Huang, Y., He, X., Yuan, J., & Dang, B. (2025) · Biomedical Reports · doi:10.3892/br.2025.1966 · Cited by 53 · see citing works

Transplantation of an adipose stem cell cluster in a spinal cord injury

Oh, J. S., Park, I., Kim, K. N., Yoon, D. H., Kim, S.-H., & Ha, Y. (2012) · Neuroreport · doi:10.1097/wnr.0b013e3283505ae2 · Cited by 51 · see citing works

The role of angiogenic and wound-healing factors after spinal cord injury in mammals

Kundi, S., Bicknell, R., & Ahmed, Z. (2013) · Neuroscience Research · doi:10.1016/j.neures.2013.03.013 · Cited by 52 · see citing works

Nitric oxide donor up‐regulation of SDF1/CXCR4 and Ang1/Tie2 promotes neuroblast cell migration after stroke

Cui, X., Chen, J., Zacharek, A., Roberts, C. J., Yang, Y., & Chopp, M. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21836 · Cited by 53 · see citing works

Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery

Nam, H. S., Kwon, I. W., Lee, B. H., Kim, H. J., Kim, J., An, S., Lee, O.-H., Lee, P. H., Kim, H. O., Namgoong, H., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144218 · Cited by 52 · see citing works

Intravenous Administration of Human Bone Marrow Stromal Cells Induces Angiogenesis in the Ischemic Boundary Zone After Stroke in Rats

Chen, J., Zhang, Z. G., Li, Y., Wang, L., Xu, Y. X., Gautam, S. C., Lü, M., Zhu, Z., & Chopp, M. (2003) · Circulation Research · doi:10.1161/01.res.0000063425.51108.8d · Cited by 652 · see citing works

Bone marrow stromal cells enhance the angiogenesis in ischaemic cortex after stroke: involvement of notch signalling

Guo, F., Lv, S., Lou, Y., Tu, W., Liao, W., Wang, Y., & Deng, Z. (2012) · Cell Biology International · doi:10.1042/cbi20110596 · Cited by 62 · see citing works

Over-expression of VEGF in Marrow Stromal Cells Promotes Angiogenesis in Rats with Cerebral Infarction via the Synergistic Effects of VEGF and Ang-2

赖天宝, 李嫚, 郑丽芳, 宋艳玲, 徐小丽, 郭远瑾, 张远, 张宗胜, & 梅元武 (2012) · 华中科技大学学报：医学英德文版

Increasing Ang1/Tie2 expression by simvastatin treatment induces vascular stabilization and neuroblast migration after stroke

Chen, J., Cui, X., Zacharek, A., & Chopp, M. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00380.x · Cited by 65 · see citing works

Intravenous Injection of Clinical Grade Human MSCs after Experimental Stroke: Functional Benefit and Microvascular Effect

Moisan, A., Favre, I., Rome, C., de Fraipont, F., Grillon, E., Coquery, N., Mathieu, H., Mayan, V., Naëgelé, B., Hommel, M., et al. (2016) · Cell Transplantation · doi:10.3727/096368916x691132 · Cited by 33 · see citing works